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CO_(2)BOLD assessment of moyamoya syndrome:Validation with single photon emission computed tomography and positron emission tomography imaging

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World Journal of Radiology 2016年第11期8卷 887-894页

作者： Alain Pellaton philippe bijlenga Laurie Bouchez Victor Cuvinciuc Isabelle Barnaure Valentina Garibotto Karl-Olof Lovblad Sven Haller Diagnostic and Interventional Neuroradiology Geneva University Hospitals Neurosurgery Geneva University Hospitals Nuclear Medicine Geneva University Hospitals

AIM To compare the assessment of cerebrovascular reserve(CVR) using CO_2 BOLD magnetic resonance imaging(MRI) vs positron emission tomography(PET) and single photon emission computed tomography(SPECT) as reference *** Ten consecutive patients(8 women, mean age of 41 ± 26 years) with moyamoya syndrome underwent 14 presurgical evaluations for external-internal carotid artery bypass surgery. CVR was assessed using CO_2 BOLD and PET(4)/SPECT(11) with a maximum interval of 36 d, andevaluated by two experienced *** The inter-rater agreement was 0.81 for SPECT(excellent), 0.43 for PET(fair) and 0.7 for CO_2 BOLD(good). In 9/14 cases, there was a correspondence between CO_2 BOLD and PET/SPECT. In 4/14 cases, CVR was over-estimated in CO_2 BOLD, while in 1/14 case, CVR was underestimated in CO_2 BOLD. The sensitivity of CO_2 BOLD was 86% and a specificity of 43%. CONCLUSION CO_2 BOLD can be used for pre-surgical assessment of CVR in patients with moyamoya syndrome and combines the advantages of absent irradiation, high availability of MRI and assessment of brain parenchyma, cerebral vessels and surrogate CVR in one stop.

关键词： Moyamoya Vascular reserve CO_(2)BOLD Cerebrovascular reserve

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Diagnostic neuroradiology for the interventional neuroradiologist

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World Journal of Radiology 2013年第11期5卷 386-397页

作者： Vitor Mendes Pereira Maria Isabel Vargas Ana Marcos philippe bijlenga Ana Paula Narata Sven Haller Karl-Olof Lvblad Service Neuro-diagnostique et Neuro-interventionnel Geneva University Hospitals Service de Neurochirurgie HUG Geneva University Hospitals

In order to further improve the impact of the continuously evolving neurointerventional techniques, the interventional neuroradiologist needs to have at his disposal more powerful techniques to image the central nervous system. With the recent development of diagnostics techniques that are computed tomography and magnetic resonance based we are now able to assess not just morphology, but also physiology, physiopathology and function. This review discusses the place of diagnostic techniques in the evaluation that the interventional neuroradiologist hast to make when confronted with patients. We provide an overview of current techniques for the brain and spine.

关键词： Neuroradiology Brain Imaging Magnetic resonance Interventional radiology

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