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International guideline on natural orifice specimen extraction surgery(NOSES)for colorectal cancer(2023 version)

Holistic Integrative Oncology 2023年第1期2卷 93-100页

作者： Zheng Liu Xu Guan Mingguang Zhang Xiyue Hu Ming Yang Junge Bai Jun Li Shaojun Yu Kefeng Ding Qingsi He Liang Kang Dan Ma Chuangang Fu Junhong Hu Ye Wei Donghui Sun Gang Yu Songbing He Changyou Wang Yanwei Gao Guiyu Wang Hongliang Yao Jian Peng Yangchun Zheng Bo Jiang Taiyuan Li Zhiguo Xiong Xuejun Sun Zhenning Wang William Meng William Tzu-Liang Chen Ming-Yin Shen John H.Marks Charles A.Ternent Darcy DShaw Jim SKhan petr Tsarkov Inna Tulina Sergey Efetov Joaquim Manuel da Costa Pereira Fernanda Nogueira Ricardo Escalante Joel Leroy Avanish Saklani Audrius Dulskas Cuneyt Kayaalp Atsushi Nishimura Kay Uehara Woo-Yong Lee Sang-Hoo Kim Suk-Hwan Lee Xishan Wang Committee of Colorectal Cancer Society Chinese Anti-Cancer Association International NOSES Alliance Department of Colorectal Surgery National Cancer CenterNational Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100021China Department of Colorectal Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of General Surgery Shandong University Qilu HospitalJinanShandongChina Department of Colorectal Surgery The Sixth Affiliated HospitalSun Yat-Sen UniversityGuangzhouChina Department of General Surgery Xinqiao HospitalThird Military Medical UniversityChongqingChina Department of Gastrointestinal Surgery Shanghai East HospitalTongji University School of MedicineShanghaiChina Department of Anorectal Surgery First Affiliated HospitalZhengzhou UniversityZhengzhouHenanChina Department of General Surgery Zhongshan HospitalFudan UniversityShanghaiChina Department of Gastric and Colorectal Surgery Jilin University First HospitalChangchunChina Department of General Surgery Qilu Hospital(Qingdao)Cheeloo College of MedicineShandong UniversityJinanChina Department of General Surgery the First Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina Affiliated Hospital of North China University of Science and Technology TangshanHebeiChina Inner Mongolia Autonomous Region People’s Hospital HuhhotInner Mongolia Autonomous RegionChina Department of Colorectal Cancer Surgery the Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangChina Department of General Surgery The Second Xiangya HospitalCentral South UniversityChangshaHunanChina Department of General Surgery Xiangya HospitalCentral South UniversityChangshaChina Department of Gastrointestinal Surgery Sichuan Cancer HospitalChengduChina Department of Colorectal and Anal Surgery Shanxi Cancer HospitalTaiyuanShanxiChina Department of General Surgery The First Affiliated Hospital of Nanchang UniversityNanchangChina Department of Gastrointestinal Surgery Hubei Provincial Cancer Hosp

Purpose In recent years,natural orifice specimen extraction surgery(NOSES)has gained widespread attention as an alternative *** the safety and feasibility of NOSES have been well documented,many questions remain open for *** aim of this guideline is to provide more evidence for the promotion of *** This guideline has been prepared by the CACA Committee of Colorectal Cancer Society and the International NOSES Alliance,based on the latest *** The guideline on NOSES for colorectal cancer include the definition,classification,technology requirement,indications,technical difficulties and clinical *** The guideline provides a full introduction of the theoretical and technical aspects of NOSES for colorectal cancer which will beneficial to development of NOSES.

关键词： Colorectal cancer Guideline Treatment Surgery Holistic integrative medicine Natural orifice specimen extraction surgery

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人源大麻素受体CB2的晶体结构

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科学新闻 2020年第2期 33-33页

作者：刘志杰 Xiaoting Li Tian Hua Kiran Vemuri Jo-Hao Ho Yiran Wu Lijie Wu petr Popov Othman Benchama Nikolai Zvonok K'ara Locke Lu Qu Gye Won Han Malliga R.Iyer Resat Cinar Nathan J.Coffey Jingjing Wang Meng Wu sevolod Katritch Suwen Zhao George Kunos Laura M.Bohn Alexandros Makriyannis Raymond C.Stevens 上海科技大学

文章简介大麻素受体CB2主要分布在人体的免疫系统,选择性调控大麻素受体CB2对炎症、纤维化及神经退行性疾病等具有较好的治疗潜力,同时可避免由大麻素受体CB1引起的精神活性。本研究报道了大麻素受体CB2与新型拮抗剂AM0257复合物2.8埃... 详细信息

文章简介大麻素受体CB2主要分布在人体的免疫系统,选择性调控大麻素受体CB2对炎症、纤维化及神经退行性疾病等具有较好的治疗潜力,同时可避免由大麻素受体CB1引起的精神活性。本研究报道了大麻素受体CB2与新型拮抗剂AM0257复合物2.8埃分辨率的晶体结构。经结构对比分析,发现同处于拮抗状态的CB2与CB1不但结构差别极大,拮抗状态的CB2-AM0257复合物结构

关键词：大麻素受体 CB2 晶体结构

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五羟色胺2C受体结构揭示GPCR多重药理学特性的结构基础

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科学新闻 2019年第2期 48-48页

作者：彭瑶 John D.McCorvy Kasper Harps?e Katherine Lansu Shuguang Yuan petr Popov Lu Qu Mengchen Pu Tao Che Louise F.Nikolajsen Xi-Ping Huang Yiran Wu Ling Shen Walden E.Bj?rn-Yoshimoto Kang Ding Daniel Wacker Gye Won Han Jianjun Cheng Vsevolod Katritch Anders A.Jensen Michael A.Hanson Suwen Zhao David E.Gloriam Bryan L.Roth Raymond C.Stevens 刘志杰上海科技大学iHuman研究所中国科学院生物物理研究所上海科技大学

文章简介有些药物往往需要作用于多个靶点,即多重药理学作用发挥其疗效。目前,针对多种血清素受体的药物,包括5-HT2C受体,对治疗肥胖、药物滥用和精神分裂症意义重大。开发具有针对5-HT2C受体选择性的配体或设计具有明确的多重药理学特... 详细信息

文章简介有些药物往往需要作用于多个靶点,即多重药理学作用发挥其疗效。目前,针对多种血清素受体的药物,包括5-HT2C受体,对治疗肥胖、药物滥用和精神分裂症意义重大。开发具有针对5-HT2C受体选择性的配体或设计具有明确的多重药理学特征的药物仍然是极其困

关键词：五羟色胺

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