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Evidence of abnormal hot carrier thermalization at van Hove singularity of twisted bilayer graphene

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Science Bulletin 2024年第16期69卷 2522-2528页

作者： Nianze Shang chen Huang Qing chen chang Liu Guangjie Yao Zhipei Sun Sheng Meng Kaihui Liu Hao Hong State Key Laboratory for Mesoscopic Physics Frontiers Science Center for Nano-optoelectronicsSchool of PhysicsPeking UniversityBeijing 100871China QtF centre of Excellence Department of Electronics and NanoengineeringAalto UniversityEspoo 02150Finland Institute of Physics Chinese Academy of SciencesBeijing 100190China Songshan Lake Materials Lab Institute of PhysicsChinese Academy of SciencesDongguan 523808China Interdisciplinary Institute of Light-Element Quantum Materials and Research centre for Light-Element Advanced Materials Peking UniversityBeijing 100871China

Interlayer twist evokes revolutionary changes to the optical and electronic properties of twisted bilayer graphene(tBG)for electronics,photonics and *** the ground state responses in tBG have been vastly and clearly studied,the dynamic process of its photoexcited carrier states mainly remains ***,we unveil the photoexcited hot carrier dynamics in tBG by time-resolved ultrafast photoluminescence(PL)autocorrelation *** demonstrate the unconventional ultrafast PL emission between the van Hove singularities(VHSs)with a~4 times prolonged relaxation *** intriguing photoexcited carrier behavior is ascribed to the abnormal hot carrier thermalization brought by bottleneck effects at VHSs and interlayer charge distribution *** study on hot carrier dynamics in tBG offers new insights into the excited states and correlated physics of graphene twistronics systems.

关键词： twisted bilayer graphene van Hove singularity Ultrafast photoluminescence Hot carrier dynamics

An unhappy triad:Hemochromatosis, porphyria cutanea tarda and hepatocellular carcinoma-A case report

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World Journal of Gastroenterology 2007年第13期13卷 1998-2001页

作者： Martina t Mogl Andreas Pascher Sabine J Presser Michael Schwabe peter Neuhaus Natascha c Nuessler Department of Surgery Charité Campus Virchow-Klinikum Augustenburger Platz 1 Berlin 13353 Germany

Liver fibrosis and cirrhosis are predisposing factors for the development of hepatocellular carcinoma （Hcc）. Hemosiderosis has also been described to trigger carcinogenesis. A significant iron overload, as found in hereditary hemochromatosis （HHc）, is a risk factor for Hcc and may also promote the symptoms of porphyria cutanea tarda （Pct）. A 68-year old male patient presented to our clinic with a suspected Hcc, elevated alpha-fetoprotein but normal liver function tests. He reported a 25 year-old history of vitiligo upon exposure to sunlight. the patient underwent an extended left hemihepatectomy, and the recovery was uneventful, with the exception of a persistent hyperbilirubinemia. Perfusion problems and extrahepatic cholestasis were ruled out by ct-scan with angiography and MR-cholangiopancreatography. However, MR1 showed an iron overload. Histology confirmed the Hcc （pt3, pN0, G3, R0） and revealed a portal fibrosis and hemosiderosis. Based on the skin lesions we suspected a Pct that was confirmed by laboratory tests showing elevated porphyrin, uroporphyrin, coproporphyrin and porphobilinogen. concurrently, molecular diagnostics revealed homozygosity for the c282Y mutation within the hemochromatosis HFE gene. After phlebotomy and normalization of liver function tests the patient was discharged. this is the first case ever showing the unusual combination of Hcc in a fibrotic liver with HHc and Pct. this diagnosis not only warrants oncological follow-up but also symptomatic therapy to normalize iron metabolism and thereby improve liver function and alleviate the symptoms of HHc and Pct. thus progression of fibrosis may be prevented and liver regeneration supported.

关键词： Hepatocellular carcinoma Hemochromatosis Porphyria cutanea tarda

A new localization theory of adaptive machining of near-net-shape blades

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chinese Journal of Aeronautics 2021年第6期34卷 18-32页

作者： Neng WAN Xiaogang SHEN Zhiyong chang Zezhong c.cHEN Department of Mechanical Engineering Northwestern Polytechnical UniversityXi'an 710072China Department of Mechanical Industrial and Aerospace EngineeringConcordia UniversityMontrealQuebec H3G IMSCanada

In the fabrication of aero-engine blades,a great deal is gained when massive material removal is avoided at the end of the process,and as little as possible material is left on the blade *** to the uncertainty of pre-process,the billet shapes are ***,the near-net-shape billet doesn’t cover the blade design surface to be ***,blade localization is necessary for these billets before the *** conventional localization methods,the design surface’s location focused on guaranteeing enough material to be ***,because the to-becut surface is in near-net and free-form shape,it is difficult to find a valid localized surface model to generate the tool *** from the localized surface is taken as rigid in previous investigation,it is allowed to deviate from the design surface no more than the tolerance *** term of this principle,the tolerance band is utilized to promote localization ability.A series of optimization models with different priorities is established to avoid the abandonment expensive blade ***,with the experiments performed on the near-net-shape blades,the blade localization theory and the promotion of localization ability are verified.

关键词： Blade localization curvature constraint Machining surface Near-net-shape blade tolerance constraint

StcF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.c.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.cai H.cai J.J.cao Q.H.cao X.cao Z.cao Q.chang K.t.chao D.Y.chen H.chen H.X.chen J.F.chen K.chen L.L.chen P.chen S.L.chen S.M.chen S.chen S.P.chen W.chen X.chen X.F.chen X.R.chen Y.chen Y.Q.chen H.Y.cheng J.cheng S.cheng t.G.cheng J.P.Dai L.Y.Dai X.c.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich c.Q.Feng X.Feng Y.t.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge c.Q.Geng L.S.Geng A.Gilman L.Gong t.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.c.Gui A.Q.Guo F.K.Guo J.c.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou t.J.Hou Y.R.Hou c.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.c.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.t.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang B.c.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev c.H.Li c.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li t.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.t.Liang G.R.Liao L.Z.Liao Y.Liao c.X.Lin D.X.Lin X.S.Lin B.J.Liu c.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu t.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long c.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo t.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian c.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin t.L.Qiu J.Rademacker c.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia cAS Key Laboratory of theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom central china Normal University Wuhan 430079China central South University Changsha 410083China china University of Geosciences Wuhan 430074China china University of Mining and technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

the superτ-charm facility(StcF)is an electron–positron collider proposed by the chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** StcF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPcII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** StcF project in china is under development with an extensive R&D *** document presents the physics opportunities at the StcF,describes conceptual designs of the StcF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity StcF detector conceptual design

Analysis of data for γp → f1(1285)p photoproduction

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chinese Physics c 2024年第2期48卷 141-152页

作者：王爱超韦能昌黄飞 college of Science China University of Petroleum(East China)Qingdao 266580China School of Physics Henan Normal UniversityXinxiang 453007China School of Nuclear Science and technology University of Chinese Academy of SciencesBeijing 101408China

the photoproduction of the f1(1285)meson off the proton target is investigated within an effective Lagrangian *** t-channelρ-andω-exchange diagrams,u-channel nucleon-exchange diagram,generalized contact term,and s-channel pole diagrams of the nucleon and a minimal number of nucleon resonances are taken into account in constructing the reaction amplitudes to describe the experimental *** different models,that is,the Feynman,Regge,and interpolated Regge models,are employed,where the t-channel reaction amplitudes are constructed in Feynman,Regge,and interpolated Regge types,*** results show that neither the Feynman model with two nucleon resonances nor the interpolated Regge model with one nucleon resonance can satisfactorily reproduce the available data forγp→f1(1285)***,in the Regge model,when any one of the N(1990)7/2^(+),N(2000)5/2^(+),N(2040)3/2^(+),N(2060)5/2^(-),N(2100)1/2^(+),N(2120)3/2^(-),N(2190)7/2^(-),N(2300)1/2^(+),and N(2570)5/2^(-)resonances is considered,the data can be well *** resulting resonance parameters are consistent with those advocated in the Particle Data Group(PDG)*** analysis shows that,in the high-energy region,the peaks of γp→f1(1285)p differential cross sections at forward angles are dominated by the contributions from t-channelρ-andω-exchange diagrams,while in low-energy region,the s-channel pole diagrams of resonances also provide significant contributions to theγp→f1(1285)p cross sections.

关键词： photoproduction reactions effective Lagrangian approach nucleon resonances

Prevention of metabolic decompensation in an infant with mutase deficient methylmalonic aciduria undergoing cardiopulmonary bypass

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World Journal of Pediatrics 2014年第1期10卷 83-85页

作者： Raymond Y Wang Richard c chang Mary E Sowa Anthony c chang Jose E Abdenur Division of Metabolic Disorders CHOC Children's FoundationDepartment of PediatricsUniversity of California Irvine School of MedicineOrangeCAUSA Department of clinical Nutrition and Lactation CHOC Children'sOrangeCAUSA Division of cardiology Pediatric Subspecialty FacultyHeart InstituteCHOC Children'sOrangeCAUSA

Background:Effects of circulatory arrest upon an inborn error of metabolism patient are ***:A retrospective chart review was performed of outcome and biochemical parameters obtained during palliative cardiac surgery for a mutase-deficient methylmalonic aciduria patient with Ebstein’s cardiac anomaly was ***:the levels of ammonia,methylmalonic acid,free carnitine,and propionylcarnitine of the patient were *** patient survived surgery following institution of four metabolic treatment principles:1)restriction of toxic substrate;2)promotion of anabolism via administration of carbohydrate and lipid calories;3)administration of detoxifying levocarnitine and sodium benzoate;and 4)cobalamin enzymatic co-factor *** patient died from post-operative dysrhythmia and was posthumously determined to have compound heterozygosity for mutations predicting severe,cobalamin non-responsive disease:c.322c>t/c.1233del3(p.R108c/p.ΔI412).conclusion:Metabolic decompensation is preventable during cardiopulmonary bypass and cardioplegia using four principles of metabolic treatment.

关键词： bypass management methylmalonic aciduria

Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKt signaling via PHLPP1 in colorectal cancer

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cancer Biology & Medicine 2020年第2期17卷 343-356页

作者： Yijye chern peter Zhang Hyelim Ju Isabella t.tai Division of Gastroenterology Department of MedicineUniversity of British ColumbiaVancouver V6T 1Z4Canada Michael Smith Genome Sciences center British Columbia Cancer AgencyVancouver V5Z 4S6Canada

Objective:Heat shock protein 47(HSP47)is a collagen-specific molecular chaperone that facilitates collagen *** role in cancer remains largely *** this study,we investigated the roles o f HSP47 in colorectal cancer(cRc)and therapy ***:Expression o f HSP47 in cRc tissues was examined(1)in paired human cRc/adjacent normal tissues,using real time quantitative reverse transcription polymerase chain reaction(qRt-PcR),the cancer Genome Atlas(tcGA)database,and 22 independent m icroarray databases(curated cRc).In vitro studies on several cRc cell lines(H c t 116,RKO and c c L228)with modulated HSP47 expression were conducted to assess cell viability and apoptosis(tU N EL assay and caspase-3/-7)during exposure to *** signaling and co-imm unoprecipitation studies were performed to examine HSP47 and PHLPP1 *** vivo studies using tumor xenografts were conducted to assess the effects of HSP47 modulation on tum or growth and therapy ***:HSP47 was upregulated in cRc and was associated with poor prognosis in individuals with *** vitro,HSP47 overexpression supported the survival of cRc cells,whereas its knockdown sensitized cells to 5-fluorouracil(5-FU).HSP47 promoted survival by inhibiting apoptosis,enhancing AKt phosphorylation,and decreasing expression of the AKt-specific phosphatase PHLPP1 when cells were exposed to *** effects were partly results of the interaction between HSP47 and PHLPP1,which decreased PHLPP1 stability and led to more persistent AKt *** vivoy HSP47 supported tumor growth despite 5-FU ***:HSP47 supports the growth of cRc tumors and suppresses the efficacy of chemotherapy via modulation of AKt signaling.

关键词： HSP47 AKt PHLPP1 colorectal cancer resistance

Evaluation of Haney-type Surface thermalBoundary conditions Using a coupledAtmosphere and Ocean Model

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Advances in Atmospheric Sciences 2001年第3期18卷 355-375页

作者： peter c. chu 陈玉春吕世华 Department of Oceanography Naval Postgraduate School

A coupled atmosphere-ocean model developed at the Institute for Space Studies at NASA Goddard Space Flight center (Russell et al., 1995) was used to verify the validity of Haney-type surface thermal boundary condition, which linearly connects net downward surface heat fluxQ to air/sea temperature difference Δt by a relaxation coefficientk. the model was initiated from the National centers for Environmental Prediction (NcEP) atmospheric observations for 1 December 1977, and from the National Ocean Data center (NODc) global climatological mean December temperature and salinity fields at 1°x 1° resolution. the time step is 7.5 minutes. We integrated the model for 450 days and obtained a complete model-generated global data set of daily mean downward net surface fluxQ, surface air temperaturet A, and sea surface temperaturet O. then, we calculated the cross-correlation coefficients (ccc) betweenQ and Δt. the ensemble mean ccc fields show (a) no correlation betweenQ and Δt in the equatiorial regions, and (b) evident correlation (ccc≥0.7) betweenQ and Δt in the middle and high latitudes. Additionally, we did the variance analysis and found that whenk=120 W m?2K?1, the two standard deviations, σQ and σκδt , are quite close in the middle and high latitudes. these results agree quite well with a previous research (chu et al., 1998) on analyzing the NcEP re-analyzed surface data, except that a smaller value ofk (80 W m?2K?1) was found in the previous study. Key words Air-sea coupled system - Ocean surface fluxes - Surface thermal boundary condition

关键词： Air-sea coupled system Ocean surface fluxes Surface thermal boundary condition

多元ti-cu基合金非晶形成过程的分子动力学模拟与落管实验研究

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中国科学：技术科学 2024年第3期54卷 477-489页

作者：徐山森常健翟斌燕鹏旭林茂杰魏炳波西北工业大学物理科学与技术学院西安710072

采用DeePMD计算方法和落管快速凝固实验技术,研究了液态ti_(41.5)cu_(37.5)Ni_(7.5)Hf_(5)Sn_(5)Zr_(2.5)Si合金的非晶凝固机制.分子动力学计算结果显示,液态合金原子的总第一近邻配位数随系统温度的降低而增加,而ti原子的第一近邻原子... 详细信息

采用DeePMD计算方法和落管快速凝固实验技术,研究了液态ti_(41.5)cu_(37.5)Ni_(7.5)Hf_(5)Sn_(5)Zr_(2.5)Si合金的非晶凝固机制.分子动力学计算结果显示,液态合金原子的总第一近邻配位数随系统温度的降低而增加,而ti原子的第一近邻原子数则随着温度的降低而减少.同时,随着系统温度的降低,液态合金中二十面体和类二十面体团簇的数量显著增多,但中心ti原子的比例却发生了衰减.在非晶凝固过程中,ti原子表现出与大尺寸原子的弱亲和性和对二十面体团簇的弱构建性.在自由落体实验中,合金液滴所能达到的过冷度随液滴直径的减小而增大,其凝固组织主要由少量的富cu相、极细的非规则(ti_(2)cu+ticu)共晶和非晶相组成.当合金液滴直径减小至566μm时,合金凝固组织中开始出现非晶相,相应的临界过冷度Δt_(c)为312 K(0.27t_(L)).非晶相体积分数随着液滴尺寸的减小而增大.如果合金液滴直径小于317μm,晶体相的形核与生长被完全抑制,凝固组织由全部非晶相组成.

关键词：非晶合金分子动力学液态结构自由落体深过冷