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Windtunnel studies of surface shear stress vector distribution measurement using shear sensitive liquid crystal coatings

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Science China(Technological Sciences) 2011年第10期54卷 2730-2734页

作者： ZHAO JiSong scholz peter GU LiangXian School of Astronautics Northwestern Polytechnical University Xi'an 710072 China Institute of Fluid Mechanics TU Braunschweig Braunschweig 38106 Germany

Shear sensitive liquid crystal coating (SSLCC) can measure surface shear stress vector distribution efficiently with a high spa-tial resolution. The purpose of the present paper is to modify and extend the surface shear stress measurement technique de-termined by Reda et al. to wind tunnel studies. All the facilities employed in the technique are very common and simple. The measurement technique is applied to surface flow beneath a tangential jet and surface flow in a turbulence wedge generated by a small cylinder in windtunnel flow. Spatially resolved shear stresses over planar surface are obtained, although the magnitude is not fully calibrated.

关键词： shear sensitive liquid crystal surface shear stress measurement tangential jet flow turbulence wedge

Color change characteristics of two shear-sensitive liquid crystal mixtures (BCN/192, BN/R50C) and their application in surface shear stress measurements

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Chinese Science Bulletin 2011年第27期56卷 2897-2905页

作者： ZHAO JiSong scholz peter GU LiangXian School of Astronautics Northwestern Polytechnical University Xi'an 710072 China Institute of Fluid Mechanics TU Braunschweig Braunschweig 38106 Germany

A previously determined surface shear stress measurement technique using shear-sensitive liquid crystal (SSLC) coating is extended for use in wind tunnel-like conditions. Simple and common everyday equipment is used in the measurement; in particular a tungsten halogen light bulb provides illumination. The color change characteristics of two SSLC mixtures, BCN192 and BN/ R50C, are investigated. BCN/192 is found sensitive to both magnitude and direction of the shear stress at different shear stress levels with little noise, and is suitable for surface shear stress distribution measurements. The spatial shear stress vector distribution beneath a tangential jet is obtained using BCN/192, although the magnitude is not fully calibrated. BN/R50C is found to be sensitive to shear stress magnitude, but only slightly sensitive to shear stress direction at both low and high levels. Moreover, jumps in the reflected hue are found when the viewing orientation is perpendicular to the shear stress direction. These characteristics render the use of BN/R50C for surface shear stress measurement difficult.

关键词：应力敏感应力测量剪切应力颜色变化混合物表面液晶特征

Process Design for Hybrid Sheet Metal Components

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Acta Metallurgica Sinica(English Letters) 2015年第12期28卷 1518-1524页

作者： Rico Haase Roland Müller Dirk Landgrebe peter scholz Matthias Riemer Fraunhofer Institute for Machine Tools and Forming Technology IWU

The global trends towards improving fuel efficiency and reducing CO;emissions are the key drivers for lightweight solutions. In sheet metal processing, this can be achieved by the use of materials with a supreme strength-toweight and stiffness-to-weight ratio. Besides monolithic materials such as high-strength or light metals, in particular metal–plastic composite sheets are able to provide outstanding mechanical properties. Thus, the adaption of conventional, wellestablished forming methods for the processing of hybrid sheet metals is a current challenge for the sheet metal working industry. In this work, the planning phase for a conventional sheet metal forming process is studied aiming at the forming of metal–plastic composite sheets. The single process steps like material characterization, FE analysis, tool design and development of robust process parameters are studied in detail and adapted to the specific properties of metal–plastic composites. In material characterization, the model of the hybrid laminate needs to represent not only the mechanical properties of the individual combined materials, but also needs to reflect the behaviour of the interface zone between *** on experience, there is a strong dependency on temperature as well as strain rate. While monolithic materials show a moderate anisotropic behaviour, loads on laminates in different directions generate different strain states and completely different failure modes. During the FE analysis, thermo-mechanic and thermo-dynamic effects influence the temperature distribution within tool and work pieces and subsequently the forming behaviour. During try out and production phase,those additional influencing factors are limiting the process window even more and therefore need to be considered for the design of a robust forming process. A roadmap for sheet metal forming adjusted to metal–plastic composites is presented in this paper.

关键词： Characterization Hybrids Interface Layered structures Processing Sheet forming

First genome-wide association study of 99 body measures derived from 3-dimensional body scans

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Genes & Diseases 2022年第3期9卷 777-788页

作者： Andreas Kuhnapfel peter Ahnert Katrin Horn Holger Kirsten Markus Loeffler Markus scholz Institute for Medical Informatics Statistics and Epidemiology(IMISE)Medical FacultyLeipzig UniversityHartelstrafte 16-18Leipzig 04107Germany LIFE Research Center for Civilization Diseases Medical FacultyLeipzig UniversityPhilipp-Rosenthal-Strafie 27Leipzig 04103Germany Integrated Research and Treatment Center(IFB) Adiposity DiseasesUniversity Medical CenterLeipzig UniversityPhilipp-Rosenthal-Strafle 27Leipzig 04103Germany

Body height,body mass index,hip and waist circumference are important risk factors or outcome variables in clinical and epidemiological research with complex underlying ***,these classical anthropometric traits represent only a very limited view on the human body and other traits with potentially higher functional specificity are not yet studied to a larger *** of LIFE-Adult were assessed by three-dimensional body scanner VITUS XXL determining 99 high-quality anthropometric traits in *** was performed by Axiom Genome-Wide CEU 1 Array Plate microarray technology and imputation was done using 1000 Genomes phase 3 reference *** phenotype and genetic information are available for a total of 7,562 *** heritabilities were estimated for height traits(maximum heritability with h2=44%for neck height)and 61 traits achieved values larger than 20%.By genome-wide analyses,we identified 16 loci associated with at least one of the 99 *** of these loci were not described for association with classical anthropometric traits so *** strongest novel association was observed for 7p14.3(rs11979006,P=2.12×10^(-9))for the trait Back Width with ZNRF2 as the most plausible candidate *** established for association with classical anthropometric traits were subjected to anthropometric phenome-wide association *** the reported 709 loci,211 *** with body scanner traits(enrichment:OR=1.96,P=1.08×10^(-61)).We conclude that genetics of 3D laser-based anthropometry is promising to identify novel loci and to improve the functional understanding of established ones.

关键词： 3D-anthropometry Genetic correlation GWAS Heritability PheWAS

Classification of different sustainable flood retention basin types

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Journal of Environmental Sciences 2010年第6期22卷 898-903页

作者： Michelle Robinson Miklas scholz Nicolas Bastien Jennifer Carfrae Scottish Agricultural College Peter Wilson Building Institute for Infrastructure and Environment School of EngineeringThe University of EdinburghWilliam Rankine Building School of Built Environment Heriot-Watt University

Using a revised version of a previously published expert classification system, a database of potential Sustainable Flood Retention Basins has been developed for Scotland. The research shows that the majority of small and former （often old） drinking water reservoirs are kept full and their spillways are continuously in operation. Utilising some of the available capacity to contribute to flood control could significantly reduce the costs of complying with the European Union Flood Directive. Furthermore, the application of a previously developed classification model for Baden in Germany for the Scottish data set showed a lower diversity for basins in Scotland due to less developed infrastructure. The classification system appears to be robust and has the potential, with minor modifications, to be applied across Europe. The principle value of this approach is a clear and unambiguous categorisation, based on standard variables, which can help to promote communication and understanding between stakeholders.

关键词： classification system diffuse pollution control principal component analysis runoff control sustainable flood retention basin

The GYF domain protein CD2BP2 is critical for embryogenesis and podocyte function

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分子细胞生物学报:英文版 2015年第5期7卷 402-414页

作者： Gesa I.Albert Christoph Schell Karin M.Kirschner Sebastian Schafer Ronald Naumann Alexandra Muller Oliver Kretz Benno Kuropka Mathias Girbig Norbert Hubner Eberhard Krause Holger scholz Tobias B.Huber Klaus-peter Knobeloch Christian Freund Institute for Chemistry and Biochemistry Freie Universitat Berlin14195 BerlinGermany Leibniz-Institut fuer Molekulare Pharmakologie 13125 BerlinGermany Renal Division University Hospital Freiburg79106 FreiburgGermany Speman Graduate School for Medicine and Biology University of Freiburg79106 FreiburgGermany Faculty of Biology University Freiburg79106 FreiburgGermany Institute fuer Vegetative Physiologie Charité-Universitatsmedizin Berlin10117 BerlinGermany Experimental Genetics and Cardiovascular Diseases MDC13125 BerlinGermany Transgenic Core Facility Max-Planck-Institute of Molecular Cell Biology and GeneticsDresdenGermany Institute of Neuropathology University of Freiburg79106 FreiburgGermany Institute of Cell Biology&Anatomy University of Freiburg79106 FreiburgGermany BIOSS Centre for Biological Signaling Studies Albert-Ludwigs-University79106 FreiburgGermany

Scaffolding proteins play pivotal roles in the assembly of macromolecular machines such as the *** adaptor protein CD2BP2,originally identified as a binding partner of the adhesion molecule CD2,is a pre-spliceosomal assembly factor that utilizes its glycine-tyrosine-phenylalanine(GYF)domain to co-localize with spliceosomal *** far,its function in vertebrates is *** conditional gene targeting in mice,we show that CD2BP2 is crucial for embryogenesis,leading to growth retardation,defects in vascularization,and premature death at embryonic day 10.5 when *** of the protein in bone marrow-derived macrophages indicates that CD2BP2 is involved in the alternative splicing of mRNA transcripts from diverse *** the molecular level,we identified the phosphatase PP1 to be recruited to the spliceosome via the N-terminus of *** the strong expression of CD2BP2 in podocytes of the kidney,we use selective depletion of CD2BP2,in combination with next-generation sequencing,to monitor changes in exon usage of genes critical for podocyte functions,including VEGF and actin ***2BP2-depleted podocytes display foot process effacement,and cause proteinuria and ultimately lethal kidney failure in ***,our study defines CD2BP2 as a non-redundant splicing factor essential for embryonic development and podocyte integrity.

关键词： GYF domain CD2BP2 alternative splicing PP1 podocytes VEGF

Bonfils纤维气管镜用于难以预料的困难气管插管的研究(英文)

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中华急诊医学杂志 2004年第3期13卷 149-152页

作者：严敏 peter H Tonner Jens scholz Berthold Bein 浙江大学医学院附属第二医院麻醉科德国基尔大学医学院麻醉科

目的　难以预料和失败的困难气管插管是引起麻醉并发症和麻醉病死率的重要因素。本研究探讨Bon fils纤维气管镜用于处理难以预料的困难气管插管的价值。方法　 2 1例行体外循环下冠状动脉搭桥术的患者 ,经一名高年资的麻醉医生使用普通... 详细信息

目的　难以预料和失败的困难气管插管是引起麻醉并发症和麻醉病死率的重要因素。本研究探讨Bon fils纤维气管镜用于处理难以预料的困难气管插管的价值。方法　 2 1例行体外循环下冠状动脉搭桥术的患者 ,经一名高年资的麻醉医生使用普通咽喉镜两次插管失败后作为研究对象。测定Bonfils纤维气管镜插管的成功率和插管时间 ,同时测定判断困难气管插管的临床指标 :甲颏距离、Mal lampti分类、张口度、寰枕关节的活动度等。结果　除外一个患者第二次插管成功外 ,第一次插管的成功率是 95 %。平均插管时间 (5 0± 2 5 )秒。

关键词： Bonfils纤维气管镜气管插管气道病死率

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工业管道系统的导波监测(英文)

无损检测 2010年第9期32卷 691-699,703页

作者： Henry scholz CGNPC Inspection Technology Company, China(CITEC) Jinhong Liu peter Bieder Fraunhofer Institute for Nondestructive Testing Dresden Germany(IZFP-D) arXes Information Design Berlin GmbH Germany(arXes) CGNPC Inspection Technology Company China(CITEC)

许多管道和管道系统从外部仅为部分可达甚至完全不可达,如独立管道、水下管道或埋地管道。因此,如果不解决独立问题或去除管道覆盖物,就无法实现管道裂纹或腐蚀的检测,然而解决可达问题或去除覆盖物时需要花费不菲的费用甚至根本不能实... 详细信息

许多管道和管道系统从外部仅为部分可达甚至完全不可达,如独立管道、水下管道或埋地管道。因此,如果不解决独立问题或去除管道覆盖物,就无法实现管道裂纹或腐蚀的检测,然而解决可达问题或去除覆盖物时需要花费不菲的费用甚至根本不能实现。由此对长距离检测系统产生了需求。对于光杆和管的局部腐蚀检测,业界已经研制成功了基于超声的检测系统[1-3]。然而,目前由于外形尺寸以及费用等,这些系统并不适用于以SHM为目的的检测。为了完成用大量探头单元涵盖一个完整的产业厂房的检测,有必要研发新型的检测硬件、探头技术以及数据评估技术。

关键词：导波检测工业管道监测

体外循环下冠状动脉搭桥术中经颅多谱勒高强度短信号与术后神经心理学功能变化的关系(英文)

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中华急诊医学杂志 2005年第5期14卷 357-361页

作者：严敏戴安卢 Andreas Boning Sven Carstensen Jorg Kampen peter H.Tonner Jens scholz Berthold Bein 浙江大学医学院附属第二医院麻醉科杭州310009 德国基尔大学医学院麻醉科德国基尔大学医学院心胸外科

目的　评估经颅多谱勒超声(TCD) 监测术中高强度短信号(HITS) 数目能否预测术后神经心理功能变化的程度。方法　20例体外循环下行冠状动脉搭桥术的患者, 术中采用TCD监测HITS的数值, 神经心理学成套测验用于评定术后神经心理学功能的变... 详细信息

目的　评估经颅多谱勒超声(TCD) 监测术中高强度短信号(HITS) 数目能否预测术后神经心理功能变化的程度。方法　20例体外循环下行冠状动脉搭桥术的患者, 术中采用TCD监测HITS的数值, 神经心理学成套测验用于评定术后神经心理学功能的变化。结果　术中HITS的数值与术后神经心理学功能的是否有变化无关。成套测验与HITS的数值的多因素相关分析中发现RW Dg1 DG5 与HITS的数值有微弱相关。结论　体外循环过程中HITS数值的变化与术后神经心理学功能变化无关。

关键词：功能变化体外循环术后术中信号强度神经心理学功能经颅多谱勒超声冠状动脉搭桥术多因素相关分析 HITS TCD监测成套测验数值