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人类生命早期暴露组(HELIX)：项目理念与设计(续完)

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环境与职业医学 2015年第2期32卷 186-190页

作者： Martine Vrijheid Rémy Slama Oliver Robinson Leda Chatzi Muireann Coen peter van den Hazel Cathrine Thomsen John Wright Toby J.Athersuch narcis Avellana Xavier Basagana Celine Brochot Luca Bucchini Mariona Bustamante Angel Carracedo Maribel Casas Xavier Estivill Lesley Fairley Diana van Gent Juan R.Gonzalez Berit Granum Regina Grazuleviiene Kristine B.Gutzkow Jordi Julvez Hector C.Keun Manolis Kogevinas Rosemary R.C.McEachan Helle Margrete Meltzer Eduard Sabidó Per E.Schwarze Valérie Siroux Jordi Sunyer Elizabeth J.Want Florence Zeman Mark J.nieuwenhuijsen 何蓉操仪汪源金泰廙 Centre for Research in Environmental Epidemiology(CREAL) Universitat Pompeu Fabra(UPF) CIBER Epidemiologíay Salud Pública(CIBERESP) Institut national de la Santé et de la Recherche Médicale(InSERM) Institut Albert Bonniot(U823) University of Crete(UOC) HeraklionCreteGreece Imperial College London(ICL) Veiligheids-en Gezondheidsregio Gelderland Midden(VGGM) norwegian Institute of Public Health(nIPH) Bradford Institute for Health Research Sensing & Control Systems S.L.(S&C) Institut national de l’Environnement Industriel et des Risques(InERIS) Unit of Models for Ecotoxicology and Toxicology Hylobates Consulting S.R.L.(HYLO) RomeItaly Centre for Genomic Regulation(CRG) IMIM Hospital del Mar Research Insititute Grupo de Medicina Xenomica Fundación Pública Galega de Medicina Xeómica(SERGAS)CIBERERCEGENUniversidade de Santiago de CompostelaSantiago de CompostelaSpain Center of Excellence in Genomic Medicine Research King Abdulaziz UniversityJeddahKingdom of Saudi Arabia Vytauto Didziojo Universitetas(VDU) KaunusLithuania Bradford Institute for Health Research Bradford Teaching Hospitals NHS Foundation Trust(BTHFT)

3．2研究2：室外暴露传统h基于居住区评估的暴露，如室外空气污染、噪声、建筑环境，可以通过收集时间一空间活动以及（就空气污染而言）个人吸入空气量的信息，改善暴露评估和减小测量误差。例如，可替代吸入率（Kawahara等，2011）的... 详细信息

3．2研究2：室外暴露传统h基于居住区评估的暴露，如室外空气污染、噪声、建筑环境，可以通过收集时间一空间活动以及（就空气污染而言）个人吸入空气量的信息，改善暴露评估和减小测量误差。例如，可替代吸入率（Kawahara等，2011）的体力活动方面的信息与个人空气污染测量结合来评估吸入剂量。基于暴露评估的新一代地理信息系统（GIS）（Beelen等，2013;Eeflens等，2012）、遥感（Dadvand等，2012）和智能手机技术（denazelle等，2013）使评估室外暴露和整合个人活动范围及体力活动数据变得更容易。

关键词：早期暴露人类生命地理信息系统设计空气污染测量误差体力活动建筑环境

系统综述与网状Meta分析的PRISMA扩展声明

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中国循证心血管医学杂志 2016年第6期8卷 656-660,665页

作者：李志霞杨俊叶欣周凌波杨智荣孙凤詹思延 Brian Hutton Georgia Salanti Deborah M.Caldwell Anna Chaimani Christopher H.Schmid Chris Cameron John P.A.Ioannidis Sharon Straus Kristian Thorlund Jeroen P.Jansen Cynthia Mulrow Ferrán Catalá-López peter C.Gozsche Kay Dickersin Isabelle Boutron Douglas G.Altman David Moher 北京大学公共卫生学院北京100191 剑桥大学初级医疗中心

PRISMA声明旨在提高系统综述和META分析报告的完整性,该声明已经广泛用于指导系统综述和META分析的报告和发表。原始的PRISMA声明是针对两种干预措施比较的传统的系统综述与META分析而制定的,然而,随着多种干预措施比较的系统综述的发展... 详细信息

PRISMA声明旨在提高系统综述和META分析报告的完整性,该声明已经广泛用于指导系统综述和META分析的报告和发表。原始的PRISMA声明是针对两种干预措施比较的传统的系统综述与META分析而制定的,然而,随着多种干预措施比较的系统综述的发展,实施和报告这一类系统综述面临较大挑战。此时,针对网状META分析的PRISMA扩展声明应运而生,旨在提高网状META分析系统综述的报告质量。PRISMA扩展声明是由专家们通过DELPHI调查、面对面讨论和共识大会而最终确立的。PRISMA扩展声明是在原始PRISMA声明的报告清单的基础上经过修改,最终确定了32个条目,每个条目均与网状META分析报告的内容直接相关。本文对网状META分析的PRISMA扩展声明进行了阐述,对报告清单各条目进行了举例说明,并详细说明了在原始PRISMA声明的基础上新增和修改各条目的理由。此外,PRISMA扩展声明强调了在网状META分析的实际操作中需要重点关注的信息。本文的目标读者包括网状META分析的作者与读者,以及期刊杂志的编辑与同行评审。

关键词：系统综述 Meta分析网状 META分析 DELPHI 报告质量期刊杂志条目

One stop shop:backbones trees for important phytopathogenic genera:Ⅰ(2014)

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Fungal Diversity 2014年第4期 21-125页

作者： Kevin D.Hyde R.Henrik nilsson S.Aisyah Alias Hiran A.Ariyawansa Jaime E.Blair Lei Cai Arthur W.A.M.de Cock Asha J.Dissanayake Sally L.Glockling Ishani D.Goonasekara Michal Gorczak Matthias Hahn Ruvishika S.Jayawardena Jan A.L.van Kan Matthew H.Laurence C.AndréLévesque Xinghong Li Jian-Kui Liu Sajeewa S.n.Maharachchikumbura Dimuthu S.Manamgoda Frank n.Martin Eric H.C.McKenzie Alistair R.McTaggart peter E.Mortimer Prakash V.R.nair Julia Pawlowska Tara L.Rintoul Roger G.Shivas Christoffel F.J.Spies Brett A.Summerell Paul W.J.Taylor Razak B.Terhem Dhanushka Udayanga niloofar Vaghefi Grit Walther Mateusz Wilk Marta Wrzosek Jian-Chu Xu JiYe Yan nan Zhou Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China World Agroforestry Centre East Asia NodeHeilongtanKunming 650201People’s Republic of China Institute of Excellence in Fungal Research and School of ScienceMae Fah Luang UniversityChiang Rai 57100Thailand Botany and Microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Department of Biological and Environmental Sciences University of GothenburgBox 46140530 GöteborgSweden Institute of Ocean and Earth Sciences(IOES) C308Institute of Postgraduate Studies BuildingUniversity of Malaya50603 Kuala LumpurMalaysia Department of Biology Franklin&Marshall CollegeLancasterPAUSA State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101 People’s Republic of China CBS-KnAW Fungal Biodiversity Centre Uppsalalaan 83584CT UtrechtThe Netherlands Beijing Academy of Agriculture and Forestry Sciences Institute of Plant and Environment ProtectionNo.9 of ShuguanghuayuanzhongluHaidian DistrictBeijing 100097People’s Republic of China 135 Brodrick Road Eastbourne BN229RAEast SussexUK Department of Plant Systematics and Geography Faculty of BiologyUniversity of WarsawAl.Ujazdowskie 400-478WarsawPoland Department of Biology TU KaiserslauternErwin-Schrodinger-StraBe67663 KaiserslauternGermany Laboratory of Phytopathology Wageningen UniversityDroevendaalsesteeg 16708 PB WageningenThe Netherlands Royal Botanic Gardens and Domain Trust Mrs Macquaries RdSydneyNew South Wales 2000Australia Agriculture and Agri-Food Canada Central Experimental FarmOttawaONCanada United States Department of Agriculture Agriculture Research ServiceSalinasCAUSA Landcare Research Private Bag92170 AucklandNew Zealand Department of Agriculture Fisheries and ForestryEcosciences PrecinctDutton ParkQueensland 4102Australia Faculty of Veterinary and Agricultural Sciences The University of

Many fungi are pathogenic on plants and cause significant damage in agriculture and *** are also part of the natural ecosystem and may play a role in regulating plant numbers/*** identification and analysis of plant pathogenic fungi,while important,is often hampered by the scarcity of discriminatory taxonomic characters and the endophytic or inconspicuous nature of these ***(DnA sequence)data for plant pathogenic fungi have emerged as key information for diagnostic and classification studies,although hampered in part by non-standard laboratory practices and analytical *** facilitate current and future research,this study provides phylogenetic synopses for 25 groups of plant pathogenic fungi in the Ascomycota,Basidiomycota,Mucormycotina(Fungi),and Oomycota,using recent molecular data,up-to-date names,and the latest taxonomic *** laboratory protocols together with advice on their application,as well as general observations,are also *** hope to maintain updated backbone trees of these fungal lineages over time and to publish them jointly as new data *** of plant pathogenic fungi not covered by the present study are invited to join this future ***,Botryosphaeriaceae,Botryosphaeria,Botrytis,Choanephora,Colletotrichum,Curvularia,Diaporthe,Diplodia,Dothiorella,Fusarium,Gilbertella,Lasiodiplodia,Mucor,neofusicoccum,Pestalotiopsis,Phyllosticta,Phytophthora,Puccinia,Pyrenophora,Pythium,Rhizopus,Stagonosporopsis,Ustilago and Verticillium are dealt with in this paper.

关键词： Ascomycota Basidiomycota Endophytes Mucormycotina Molecular identification Oomycota Plant pathogens Protozoa

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原发性神经炎性麻风患者随访过程中出现皮损

世界核心医学期刊文摘（皮肤病学分册） 2005年第7期1卷 54-54页

作者： Suneetha S. Sigamoni A. Kurian n. Chacko C.J.G. 牛新武 LEPRA India Blue Peter Research Center Near TEC Building Cherlapally Hyderabad 501 301 India Dr.

Background: Primary neuritic leprosy (PnL) is a rare form of leprosy where the characteristic skin lesions are absent. Investigations of apparently normal skin from the areas of sensory change have revealed microscopic evidence of nerve involvement. Clinical studies have found that a proportion of patients develop visible skin lesions during follow- up. The aim of the study was to perform a clinical and histological analysis of PnL patients who developed visible skin lesions during treatment and follow- up, to gain insight into the pathogenesis of the disease. Methods: Twenty- nine individuals in a series of 182 PnL patients developed visible skin lesions during follow- up. Analysis of the number, location, histology and time of onset of the new skin lesions in relation to the type and regularity of the treatment regimen were noted. A biopsy from the new skin lesion when available was compared with the nerve biopsy findings at the time of initial diagnosis. Results: Thirty- eight per cent of patients developed a single patch and 28% developed two patches. Over three- quarters of these were on the lower limb (47% ) or the upper limb (29% ). Sixty- two per cent of patients developed the lesions within 2 years of the onset of symptoms. Patients on regular treatment developed patches earlier than those on irregular treatment or no treatment. A skin biopsy from the new patch revealed borderline tuberculoid leprosy histology in 47% of the patients. Conclusions: The findings suggest that leprosy primarily affects the nerve and that a neuritic phase precedes the development of visible cutaneous lesions.

关键词：麻风患者随访过程神经活检皮损数目组织学特征治疗规律活检标本规律治疗感觉异常治疗者

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通用分组网络寻址路由与标识演进方法及系统

中国科学：信息科学 2023年第8期53卷 1629-1644页

作者：李挥邬江兴韦国华孟详帧白鹤林立宏杨昕伊鹏宗泽斌魏进武朱伏生陆以勤缪伟豪杨伟豪郑泽峰马军锋张明龙张汉裕褚晓理何品翰王泽华北京大学深圳研究生院深圳518055 国家数字交换系统工程技术研究中心郑州450002 鹏城实验室深圳518055 中国电信股份有限公司北京100033 中国联合网络通信有限公司北京100032 广东省新一代通信与网络创新研究院广州510289 华南理工大学电子与信息学院广州510006 香港科技大学电子与计算机工程系中国香港香港中文大学信息工程系中国香港澳门科技大学资讯科技学院中国澳门中国信息通信研究院北京100191 Department of Electrical and Electronic Engineering Auckland University of TechnologyAuckland 1142NewZealand Department of Electronic and Electrical Engineering The University of SheffieldSheffield S102TNUK Department of Electrical and Computer Engineering University of WaterlooWaterloo N2L 3G1Canada Department of Electrical and Computer Engineering The University of British ColumbiaVancouver V6T 1Z2Canada

未来的网络通信需求动态多样,网络层功能也应适时而变,因此对网络可演进性的研究具有重要意义.多标识网络作为一种兼容性极强的网络架构,网络层功能十分丰富,但仍缺少网络演进性设计.本文为多标识网络设计了一种通过标识扩展来支持网络... 详细信息

未来的网络通信需求动态多样,网络层功能也应适时而变,因此对网络可演进性的研究具有重要意义.多标识网络作为一种兼容性极强的网络架构,网络层功能十分丰富,但仍缺少网络演进性设计.本文为多标识网络设计了一种通过标识扩展来支持网络体系不断演进的方案,包括对标识空间进行形式化定义,设计标识回退候选标识的优先级排序算法以及设计支持标识扩展的路由转发协议;并且在ndnSIM网络仿真环境和多标识网络测试床中实现了上述方案,评估了标识扩展方案的可行性和性能.实验结果表明相比于标识扩展机制给网络架构带来的益处,其性能损失在可接受的范围内.

关键词：多标识网络标识扩展网络演进原型系统 ndnSIM仿真

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急性卒中影像学研究路径图Ⅱ

国际脑血管病杂志 2014年第2期22卷 81-92页

作者： Max Wintermark Gregory W. Albers Joseph P. Broderick Andrew M. Demchuk Jochen B. Fiebach Jens Fiehler James C. Grotta Gary Houser Tudor G. Jovin Kennedy R. Lees Michael H. Lev David S. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Richard I. Aviv Roland Bammer Jean-Claude Baron Fernando Calamante Bruce C.V. Campbell Trevor C. Carpenter Sφren Christensen William A. Copen Colin P. Derdeyn E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrence L. Latour Ting-Yim Lee Richard Leigh Weili Lin Patrick Lyden Grant Mair Bijoy IC Menon Patrik Michel Robert Mikulik Raul G. nogueira Left φstergaard Salvador Pedraza Christian H. Riedel Howard A. Rowley Pina C. Sanelli Makoto Sasaki Jeffrey L. Saver Pamela W. Schaefer peter D. Schellinger Georgios Tsivgoulis Lawrence R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat Stephen M. Davis Geoffrey A. Donnan Anthony J. Furlan Werner Hacke Dong-Wha Kang Chelsea Kidw ell Vincent n. Thijs Gotz Thomalla Steven J. Warach 严晓铭刘牧张晶晶柯开富不详南通大学附属医院神经内科 226001

卒中影像学研究组（StrokeImagingResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stro... 详细信息

卒中影像学研究组（StrokeImagingResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stroke Treatment Academy Industry Roundtable，STAIR）期间举行。

关键词：急性卒中影像学神经放射学路径会议基金会学会美国

新斯的明降低分娩期患者A控硬膜外镇痛（PCEA）的布比卡因用量：一项随机对照研究

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麻醉与镇痛 2011年第5期7卷 22-29页

作者： Vernon H. Ross, MD peter H. Pan, MD Medge D. Owen, MD Melvin H. Seid, MD Lynne Harris, Rn Brittany Clyne, MD Misa Voltaire, MD James C. Eisenach, MD 房丽丽（译） Departments of Anesthesiology Wake Forest University School of Medidne North Carolina Obstetrics and Gynecology Wake Forest University School of Medidne North Carolina 不详

背景鞘内注射新斯的明产生镇痛作用的同时可能导致重度恶心。相反，硬膜外注射新斯的明可以增强阿片类药物和局部麻醉药的镇痛作用而不产生恶心呕吐。以往的研究只针对单次硬膜外注射新斯的明，而对连续硬膜外注射新斯的明和母婴安全性... 详细信息

背景鞘内注射新斯的明产生镇痛作用的同时可能导致重度恶心。相反，硬膜外注射新斯的明可以增强阿片类药物和局部麻醉药的镇痛作用而不产生恶心呕吐。以往的研究只针对单次硬膜外注射新斯的明，而对连续硬膜外注射新斯的明和母婴安全性未进行评估。因此，本研究拟验证在分娩期患者中新斯的明复合布比卡因硬膜外注射是否减少布比卡因用量。方法12例择期剖宫产的健康产妇随机分组，分别接受40μg（n=6）和80μg（n=6）新斯的明单次注射，监测20分钟胎心率（fetalheartrate，FHR）和宫缩。然后，另外40例健康的分娩期产妇随机分组，分别接受布比卡因1．25mg／ml或联合新斯的明4μg／ml产妇自控硬膜外镇痛（patient—controlledepiduralanalgesia，PCEA）。主要观察指标为每小时布比卡因用量。结果硬膜外新斯的明单次注射未导致FHR基础值改变，未诱导宫缩或产生恶心。硬膜外新斯的明的使用可使全部产妇的布比卡因用量减少19％，P〈0．05（使用4小时以上产妇用量减少达25％，P〈0．05），但可能导致轻度镇静。两组产妇的分娩方式、恶心发生率和FHR异常情况均相似。结论以上数据显示硬膜外使用新斯的明可降低PCEA中布比卡因每小时需要量的19％-25％。单次给药和连续注射新斯的明均不会诱发恶心、诱导宫缩或FHR异常，但可能导致轻度镇静。

关键词：自控硬膜外镇痛新斯的明布比卡因随机对照研究分娩期用量患者硬膜外注射

notes,outline and divergence times of Basidiomycota

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Fungal Diversity 2019年第6期99卷 105-367页

作者： Mao-Qiang He Rui-Lin Zhao Kevin D.Hyde Dominik Begerow Martin Kemler Andrey Yurkov Eric H.C.McKenzie Olivier Raspe Makoto Kakishima Santiago Sanchez-Ramırez Else C.Vellinga Roy Halling Viktor Papp Ivan V.Zmitrovich Bart Buyck Damien Ertz nalin n.Wijayawardene Bao-Kai Cui nathan Schoutteten Xin-Zhan Liu Tai-Hui Li Yi-Jian Yao Xin-Yu Zhu An-Qi Liu Guo-Jie Li Ming-Zhe Zhang Zhi-Lin Ling Bin Cao Vladimir Antonin Teun Boekhout Bianca Denise Barbosa da Silva Eske De Crop Cony Decock Balint Dima Arun Kumar Dutta Jack W.Fell Jozsef Geml Masoomeh Ghobad-nejhad Admir J.Giachini Tatiana B.Gibertoni Sergio P.Gorjon Danny Haelewaters Shuang-Hui He Brendan P.Hodkinson Egon Horak Tamotsu Hoshino Alfredo Justo Young Woon Lim nelson Menolli Jr Armin Mesic Jean-Marc Moncalvo Gregory M.Mueller La szlo G.nagy RHenrik nilsson Machiel noordeloos Jorinde nuytinck Takamichi Orihara Cheewangkoon Ratchadawan Mario Rajchenberg Alexandre G.S.Silva-Filho Marcelo Aloisio Sulzbacher Zdenko Tkalcec Ricardo Valenzuela Annemieke Verbeken Alfredo Vizzini Felipe Wartchow Tie-Zheng Wei Michael WeiB Chang-Lin Zhao Paul M.Kirk State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand College of Life Sciences University of Chinese Academy of SciencesHuairou DistrictBeijing 100408People’s Republic of China Ruhr-Universitat Bochum AG GeobotanikND03UniversitatsstraBe 15044801 BochumGermany Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures InhoffenstraBe 7B38124 BrunswickGermany Manaaki Whenua-Landcare Research Private Bag 92170AucklandNew Zealand Research Department Meise Botanic GardenNieuwelaan 381860 MeiseBelgium Service General de l'Enseignement superieur et de la Recherche scientifique Federation Wallonie-BruxellesLavallee 11080 BrusselsBelgium University of Tsukuba TsukubaIbaraki 305-8572Japan Department of Ecology and Evolutionary Biology University of Toronto25 Willcocks St.TorontoON M5S 3B2Canada Berkeley USA Institute of Systematic Botany The New York Botanical GardenBronxNY 10458-5126USA Department of Botany Szent Istvan University1518 BudapestHungary Komarov Botanical Institute Russian Academy of SciencesProfessor Popov st.2Saint PetersburgRussia 197376 Institut pour Systematique Ecologie Biodiversite(ISYEB UMR 7205) Sorbonne universiteMuseum National d’Histoire Naturelle CP 39CNRSDepartement Origines et Evolution12 Rue Buffon75005 ParisFrance Institute of Microbiology Beijing Forestry UniversityBeijing 100083People’s Republic of China Department of Biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Institute of MicrobiologyGuangzhou 510070People’s Republic of China Department of Botany Moravian Mu

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the *** present work provides an overview of all validly published,currently used basidiomycete genera to date in a single *** outline of all genera of Basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four *** provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence ***,three phylogenetic analyses with combined LSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,*** time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 *** study indicates that the divergence times of the subphyla in Basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous *** this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 *** times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.

关键词： Classification Molecular clock Fungi Systematics Taxonomy

Abstracts from the 15th International Myopia Conference

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Eye and Vision 2016年第1期3卷 211-221页

作者： Alexandra Benavente-Perez Ann nour Tobin Ansel Kathleen Abarr Luying Yan Keisha Roden David Troilo Chanyi Lu Miaozhen Pan Min Zheng Jia Qu Xiangtian Zhou Christine F. Wildsoet Fan Lu Jie Chen Jinhua Bao Liang Hu Qinmei Wang Zibing Jin Frances Rucker Stephanie Britton Stephan Hanowsky Molly Spatcher Hui-Ying Kuo Ching-Hsiu Ke I-Hsin Kuo Chien-Chun Peng Han-Yin Sun Ian G. Morgan Jeremy A. Guggenheim Rupal L. Shah Cathy Williams Jinglei Yang peter S. Reinach Sen Zhang Wenfeng Sun Bo Liu Fen Li Xiaoqing Li Aihua Zhao Tianlu Chen Wei Jia Jun Jiang Haoran Wu Kazuo Tsubota Hiroko Ozawa Hidemasa Torii Shigemasa Takamizawa Toshihide Kurihara Kazuno negishi Klaus Graef Daniel Rathbun Frank Schaeffel Ladan Ghodsi William K. Stell Machelle T. Pardue Ranjay Chakraborty Han na Park Curran S. Sidhu P. Michael Iuvone Michael J Collins nethrajeith Srinvasalu Sally A. McFadden Paul n. Baird Pablo Artal Pauline Cho SW Cheung Pei-Chang Wu Quan V. Hoang Duk C. Lee Erica G. Landis Michael A. Bergen Curran Sidhu Samer Hattar Richard A. Stone Ravi Metlapally Ruiqin Li Qinglin Xu Hong Zhong Chenglin Pan Weizhong Lan Xiaoning Li Ling Chen Zhikuan Yang Scott A. Read Seang-Mei Saw Shi-Jun Weng Xiao-Hua Wu Kang-Wei Qian Yun-Yun Li Guo-Zhong Xu Furong Huang Xiong-Li Yang Yong-Mei Zhong Earl L Smith, III Baskar Arumugam Li-Fang Hung Lisa A. Ostrin Klaus Trier Monica Jong Brien A. Holden Thomas Chuen Lam Samantha Shan Bing Zuo Dennis Yan-yin Tse Jingfang Bian King-Kit Li Quan Liu Chi-ho To Timothy J. Gawne John T. Siegwart, Jr. Alexander H. Ward Thomas T. norton Yan Zhang Yue Liu Carol Ho Eileen Phan Abraham Hang Emily Eng Christine Wildsoet Department of Biological Sciences SUNY College of Optometry New York NY 10036 USA School of Optometry and Ophthalmology and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China Center for Eye Disease & Development School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA Wenzhou Medical University Wenzhou Zhejiang 325027 China Biomedical Science and Disease New England College of Optom Boston MA USA School of Optometry Chung Shan Medical University Taichung City 402 Taiwan Institute of Medicine Chung Shan Medical University Taichung City 402 Taiwan Division of Biochemistry and Molecular Biology Research School of Biology Australian National University Canberra Australia State Key Laboratory of Ophthalmology and Division of Preventive Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China School of Optometry & Vision Sciences Cardiff University Cardiff UK School of Social and Community Medicine University of Bristol Bristol UK School of and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China State Key Laboratory Cultivation Base and Key Laboratory of Vision Science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China Shanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China Eye Hospital of Wenzhou Medical University Wenzhou Zhejiang 325027 China Department of Ophthalmology Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan General Medicine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalmic Research Institute University of Tuebingen 72076 Tuebingen Germany Bernstein Center for Computational neuroscience Tuebingen 72076 Tuebingen Germany Werner Reichardt Centre for Integrative neuroscience Otfried-Mueller-Straße 25 Tueb

To assess the peripheral refractive changes that occur when eye growth decelerates in *** We measured peripheral refraction and on-axis vitreous chamber depth on a total of 53 marmosets;36 treated monocularly for 12 weeks 9 hrs/day(26 with-5 D contact lenses,10 with+5 D)and 17 untreated *** the 26 marmosets treated with-5 D,10 wore contact lenses 9 hrs/day without interruptions and were mea-sured at the end of 10 weeks of treatment(T10)and after 4 weeks of recovery(R14).Eight had both contact lenses removed for 30 mins twice/day(mid-morning and mid-afternoon)during the first four weeks of treatment(early interruption group)and eight had the lenses removed during the second four weeks of treatment(late interruption group).The two interruption groups were measured after 4,8 and 12 weeks of treatment only(T4,T8,T12).

关键词： removed treatment untreated