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Virologica Sinica 2017年第1期32卷 89-96页

作者： Yanfang Zhang Shu Shen Junming Shi Zhengyuan Su Mingyue Li Wenjing Zhang Mengmeng Li Zhihong Hu Cheng peng Xin Zheng fei Deng State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Department of Infectious Diseases Institute of Infection and Immunology Union Hospital Tongji Medical CollegeHua Zhong University of Science and Technology

Hubei Province is a major epidemic area of severe fever with thrombocytopenia syndrome bunyavirus(SFTSV) in China. However, to date, a few SFTSV strains have been isolated from Hubei Province, preventing effective studies of epidemic outbreaks. Here, we report three confirmed patients(2015–2016) with typical symptoms of severe fever with thrombocytopenia syndrome disease(SFTS) who were farmers resident in different regions in Hubei Province. Three new SFTSV strains were isolated from the serum samples of each patient. Characterization of viral growth properties showed that there were no significant differences in virus production. All strains were completely sequenced, and phylogenetic analysis showed that unlike the other strains from Hubei province, which belonged to the SFTSV C3 genotype, one of the three strains belonged to the SFTSV C2 genotype. These results suggested that multiple SFTSV genotypes have been circulating in Hubei Province, providing insights into SFTSV evolution and improving our understanding of SFTSV prevalence in Hubei Province.

关键词： bunyavirus severe fever with thrombocytopenia syndrome bunyavirus (SFTSV) isolation phylogenetic analysis genotype

Significance of Lateral Pillar in Osteonecrosis of Femoral Head:A Finite Element Analysis

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Chinese Medical Journal 2017年第21期130卷 2569-2574页

作者： peng-fei Wen Wan-Shou Guo Qi-Dong Zhang Fu-Qiang Gao Ju-An Yue Zhao-Hui Liu Li-Ming Cheng Zi-Rong Li Department of Orthopaedic Surgery Peking University China-Japan Friendship School of Clinical MedicineBeijing 100029China Department of Orthopaedic Surgery Center for Osteonecrosis and Joint Preserving and ReconstructionBeijing Key Laboratory of Arthritic and Rheumatic DiseasesChina-Japan Friendship HospitalBeijing 100029China Beijing University of Chinese Medicine Beijing 100029China

Background： The lateral pillar of the femoral head is an important site for disease development such as osteonecrosis of the femoral head. The femoral head consists of medial, central, and lateral pillars. This study aimed to determine the biomechanical effects of early osteonecrosis in pillars of the femoral head via a finite element （FE） analysis. Methods： A three-dimensional FE model of the intact hip joint was constructed from the image data of a healthy control. Further, a set of six early osteonecrosis models was developed based on the three-pillar classification. The von Mises stress and surface displacements were calculated for all models. Results： The peak values of von Mises stress in the cortical and cancellous bones of normal model were 6.41 MPa and 0.49 MPa, respectively. In models with necrotic lesions in the cortical and cancellous bones, the von Mises stress and displacement of lateral pillar showed significant variability： the stress of cortical bone decreased from 6.41 MPa to 1.51 MPa （76.0% reduction）, while cancellous bone showed an increase from 0.49 MPa to 1.28 MPa （159.0% increase）; surface displacements of cortical and cancellous bones increased from 52.4 μm and 52.1 μm to 67.9 μm （29.5%） and 61.9 μm （18.8%）, respectively. In addition, osteonecrosis affected not only pillars but also adjacent structures in terms of the von Mises stress and surface displacement levels. Conclusions： This study suggested that the early-stage necrosis in the femoral head could increase the risk of collapse, especially in lateral pillar. On the other hand, the cortical part of lateral pillar was found to be the main biomechanical support of femoral head.

关键词： Displacement Finite Element Analysis Osteonecrosis of the Femoral Head Stress Structure Collapse

A retrospective monocenter review of simultaneous pancreaskidney transplantation with bladder drainage in China

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Chinese Medical Journal 2011年第2期124卷 205-209页

作者： BI Hai HOU Xiao-fei ma Lu-lin LUO Kang-ping WANG Guo-liang ZHAO Lei LIU Ya-li Department of Urology Third Hospital of Peking University Beijing 100191 China

Background Simultaneous pancreas-kidney transplantation （SPKT） frees the diabetic patient with end-stage nephropathy from dialysis and daily insulin ***,we review consecutive cases of SPKT with bladder drainage performed at our institution over an 8-year *** The study population included 21 patients （16 males and 5 females） who underwent SPKT between September 2001 and September *** patients had type-1 diabetes and 14 had type-2 *** patients were on dialysis at the time of *** after cardiac death donors were selected for *** mean human leukocyte antigen match was 2 （range 0-4）.SPKT was always performed using bladder drainage and vascular anastomoses to the systemic *** treatment consisted of anti-lymphocyte globulin induction followed by tacrolimus,mycophenolate mofetil,and *** The mean hospital stay was 45.43 *** a mean follow-up of 39.4 months,survival rates for patient,kidney,and pancreas were 76.2%,76.2%,and 66.7% at 1 year;76.2%,59.3%,and 55.6% at 5 years;and 57.1%,39.5%,and 41.7% at 8 years,*** complications included anastomotic leaks,reflux pancreatitis,and *** patients died from septic shock （n=3）,duodenal stump leak （1）,cardiac arrest （1）,or renal failure （1）.Eight kidney grafts were lost due to acute rejection （n=2）,chronic rejection （3）,and death with a functioning graft （3）.Pancreatic graft failure （9） was caused by thrombosis （n=1）,rejection （2）,duodenal stump leak （1）,and death with a functioning graft （5）.Concluslons SPKT is a valid therapeutic option for uremic diabetics although few hospitals in China can undertake SPKT.

关键词： pancreas transplantation kidney transplantation survival rate postoperative complications

11份饲用甜高粱品种在凉山州的生产性能及营养价值评价

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草地学报 2024年第9期32卷 2934-2942页

作者：董志晓熊毅熊艳丽赵俊茗张建波彭靖涵陈书明敏伟余青青马啸四川农业大学草业科技学院四川成都611130 四川省草原科学研究院四川阿坝624669 阿坝县科学技术和农业畜牧水务局四川阿坝624600

为筛选出适宜在凉山州中低海拔地区种植的饲用甜高粱品种,本研究采用随机区组设计,对11份甜高粱(Sorghum saccharatum Moench)的农艺性状、生产性能和营养成分相关指标进行测定,通过隶属函数法和Topsis(Technique for order preference ... 详细信息

为筛选出适宜在凉山州中低海拔地区种植的饲用甜高粱品种,本研究采用随机区组设计,对11份甜高粱(Sorghum saccharatum Moench)的农艺性状、生产性能和营养成分相关指标进行测定,通过隶属函数法和Topsis(Technique for order preference by similarity to an ideal solution)法进行综合分析。参试品种中‘大力士’的鲜草和干物质产量最高,分别为80850.91 kg·hm^(-2)和22234.02 kg·hm^(-2),显著高于其他品种(P<0.05)。干鲜比最大的为‘丰甜’(0.38),茎叶比最小的为‘F10’(2.07)。‘BMR 3631’的粗蛋白(Crude protein,CP)含量和相对牧草质量(Relative forage quality,RFQ)显著高于其他品种(P<0.05),中性洗涤纤维(Neutral detergent fiber,NDF)和酸性洗涤纤维(Acid detergent fiber,ADF)含量均最低。相关性分析表明鲜草产量与株高呈显著正相关关系(P<0.05),CP含量与鲜干物质产量呈显著负相关关系(P<0.05),ADF和NDF含量与株高呈极显著正相关关系(P<0.01)。隶属函数与Topsis综合分析表明‘德胜’和‘大力士’两个品种具有较高的饲草产量和营养品质,适宜在当地种植。

关键词：甜高粱品种比较生产性能营养品质隶属函数 Topsis

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在远程三方之间建立高保真的量子通信信道

长春师范大学学报 2024年第6期43卷 33-39页

作者：韩菲朱孟正淮北师范大学物理与电子信息学院

量子通信是利用量子力学原理，把微观的物质特性运用到通信技术上，在高速传输和高可靠保密通信等方面具有显著优势，成为当今通信技术领域的研究热点之一。量子通信系统的中心环节就是远程各方之间建立稳定、可靠、安全的量子信道。本... 详细信息

量子通信是利用量子力学原理，把微观的物质特性运用到通信技术上，在高速传输和高可靠保密通信等方面具有显著优势，成为当今通信技术领域的研究热点之一。量子通信系统的中心环节就是远程各方之间建立稳定、可靠、安全的量子信道。本方案基于弱交叉克尔非线性的量子非破坏(QND)光子数解析检测、交叉相位调制(XPM)技术和线性光学元件以及单比特旋转操作可高保真地制备出远程三粒子纠缠Greenberger-Horne-Zeilinger(GHZ)态，从而作为实现远程三方之间量子通信的信道。当前方案远程制备出来的GHZ态总成功率理论上是确定性的，而保真度原则上近似接近单位1。然而，在实际远距离量子通信过程中，难免会受到环境噪声的影响，从而导致保真度的降低。本方案通过以牺牲成功概率为代价，实现远程三方之间直接建立高保真度的GHZ态的纠缠共享。使用基本线性光学元件，在仅引入弱的交叉克尔非线性，且不需要额外添加辅助光子的情况下，就可以获取高保真度的GHZ纯态，证实了本方案在实际应用中具有简便性、可实现性以及资源利用率高的显著优势。

关键词：量子通信纠缠态交叉相位调制 GHZ态

Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy

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Asian Journal of Pharmaceutical Sciences 2022年第6期17卷 880-891页

作者： Shi Wang Yining Song Jingge ma Xinyang Chen Yuanhui Guan Hui peng Guoqing Yan Rupei Tang Engineering Research Center for Biomedical materials Anhui Key Laboratory of Modern BiomanufacturingSchool of Life SciencesAnhui UniversityHefei 230601China Anhui Engineering Technology Research Center of Biochemical Pharmaceutical Bengbu Medical CollegeBengbu 233030China

To achieve highly selective synergistic chemotherapy attractive for clinical translation,the precise polymeric nano-prodrugs(PPD-NPs)were successfully constructed via the facile crosslinking reaction between p H-sensitive poly(ortho ester)s and reduction-sensitive small molecule synergistic prodrug(Pt(IV)-1).PPD-NPs endowed the defined structure and high drug loading of cisplatin and demethylcantharidin(DMC).Moreover,PPD-NPs exhibited steady long-term storage and circulation via the crosslinked structure,suitable negative potentials and low critical micelle concentration(CMC),improved selective tumour accumulation and cellular internalization via dynamic size transition and surficial amino protonation at tumoural extracellular p H,promoted efficient disintegration and drug release at tumoural intracellular p H/glutathione,and enhanced cytotoxicity via the synergistic effect between cisplatin and DMC with the feed ratio of 1:2,achieving significant tumour suppression while decreasing the side ***,the dynamic crosslinked polymeric nano-prodrugs exhibit tremendous potential for clinically targeted synergistic cancer therapy.

关键词： Nano-prodrugs Precise structure Size transition Amino protonation Synergistic chemotherapy

A novel onlay urethroplasty for hypospadias with mild chordee after degloving:modified for complete removal of scar tissue underlying the urethral plate and for long-term outcomes

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Asian Journal of Andrology 2022年第6期24卷 639-642页

作者： Li-Qu Huang Zheng Ge Li-Xia Wang Xiao-Yu Li Yong-Ji Deng Yun-fei Guo Geng ma Department of Urology Children's Hospital of Nanjing Medical UniversityJiangsu Provincial Children's Medical CenterNanjing 210008China

Urethral plate(UP)-preserving urethroplasty is simple and has few complications,but it may affect the development of penis in the long term and lead to recurrent *** this study,we used obliquely cut UP to repair hypospadias with mild chordee after degloving(15°-30°)and compared the results with onlay urethroplasty to explore its rationality and *** April 2018 and October 2020,108 hypospadias patients underwent onlay urethroplasty or modified onlay *** data were prospectively collected,and medium-term outcomes were assessed at *** complications were compared between the two ***-four patients underwent the modified onlay procedure(GroupⅠ),with follow-up time(mean±standard deviation[s.d.])of 23.2±4.5(range:17-31)***-four patients underwent a standard onlay procedure(GroupⅡ),with follow-up time(mean±s.d.)of 39.7±3.9(range:32-46)*** was no difference in age at *** urethral defect length and operative time were longer in GroupⅠ.Six cases of fistula and one case each of stricture and diverticulum were reported in GroupⅠ.In GroupⅡ,11 cases of fistula and one case each of stricture and diverticulum were *** complication rates were 18.2%and 20.3%in GroupⅠand GroupⅡ,respectively(P>0.05).These medium-term follow-up results demonstrate that the modified onlay procedure(oblique cut UP urethroplasty)is a safe and feasible technique for hypospadias with mild chordee after *** with standard onlay urethroplasty,this modified procedure is conducive to the complete removal of scar tissue underlying the UP without increasing the risk of surgical complications.

关键词： complications hypospadias penile curvature urethral plate

氮化钴电催化还原二氧化碳为一氧化碳（英文）

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电化学 2019年第4期25卷 467-476页

作者：马晨侯朋飞康鹏中国科学院理化技术研究所中国科学院光化学转换与功能材料重点实验室北京100190 中国科学院大学北京100190 天津大学化工学院天津300072

电催化还原二氧化碳是一种潜在的解决全球变暖的途径,但是仍有许多挑战.本文报道了使用氮化钴在水溶液中电催化还原二氧化碳为一氧化碳.通过对比不同煅烧温度及气氛合成的催化剂表明氮掺杂对催化活性的提高至关重要.其中700-Co5.47N/C... 详细信息

电催化还原二氧化碳是一种潜在的解决全球变暖的途径,但是仍有许多挑战.本文报道了使用氮化钴在水溶液中电催化还原二氧化碳为一氧化碳.通过对比不同煅烧温度及气氛合成的催化剂表明氮掺杂对催化活性的提高至关重要.其中700-Co5.47N/C展现了最高的催化活性,在较低的电势-0.7 V(vs. RHE)下,一氧化碳的电流密度达到9.78 ma·cm-2.另外,通过改变电解电压,CO/H2的比例能在1:3到3:2之间调节. 91 mV·dec-1的Tafel斜率表明形成表面吸附的CO2·-中间体是CO2表面还原的决速步骤,而氮化策略可以增加表面碱性位点的数量,从而稳定还原的中间体,提高反应效率和产物选择性.

关键词：氮化钴二氧化碳电还原一氧化碳合成气

2020 Roadmap on two-dimensional nanomaterials for environmental catalysis

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Chinese Chemical Letters 2019年第12期30卷 2065-2088页

作者： Yulu Yang Mingguang Wu Xingwang Zhu Hui Xu Si ma Yongfeng Zhi Hong Xia Xiaoming Liu Jun Pan Jie-Yinn Tang Siang-Piao Chai Leonardo Palmisano Francesco Parrino Junli Liu Jianzhong ma Ze-Lin Wang Ling Tan Yu-fei Zhao Yu-fei Song Pardeep Singh Pankaj Raizada Deli Jiang Di Li R.A.Geioushy Jizhen ma Jintao Zhang Song Hu Rongjuan Feng Gang Liu Minghua Liu Zhenhua Li Mingfei Shao Neng Li Jiahe peng Wee-Jun Ong Nikolay Kornienko Zhenyu Xing Xiujun Fan Jianmin ma School of Physics and Electronics Hunan UniversityChangsha 410082China School of the Environment and Safety Engineering Institute for Energy ResearchJiangsu UniversityZhenjiang 212013China College of Chemistry Jilin UniversityChangchun 130012China State Key Laboratory on Integrated Optoelectronics College of Electronic Science and TechnologyJilin UniversityChangchun 130012China Key Laboratory for Powder Metallurgy Central South UniversityChangsha 410083China Multidisciplinary Platform of Advanced Engineering Chemical Engineering DisciplineSchool of EngineeringMonash UniversityJalan Lagoon SelatanBandar SunwaySelangor 47500Malaysia University of Palermo Department of EngineeringPalermo 90128Italy University of Trento Department of Industrial EngineeringTrento 38123Italy School of materials Science and Engineering Shaanxi University of Science&TechnologyXi'an 710021China College of Bioresources Chemistry and materials Engineering Shaanxi University of Science&TechnologyXi'an 710021China State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China School of Chemistry Faculty of Basic SciencesShoolini UniversitySolanHP 173229India Himalayan Centre for Excellence in Nanotechnology Shoolini UniversitySolanmHP 173229India School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China Institute for Energy Research Jiangsu UniversityZhenjiang 212013China Nanomaterials and Nanotechnology Department Advanced Materials DivisionCentral Metallurgical R&D Institute(CMRDI)Cairo 11421Egypt Key Laboratory for Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical Engineering Shandong UniversityJi'nan 250100China National Laboratory for Molecular Science(BNLMS) CAS Laboratory of ColloidInterface and Chemical ThermodynamicsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence i

Environmental catalysis has drawn a great deal ofattention due to its clean ways to produce useful chemicals or carry out some chemical *** and electrocatalysis play important roles in these *** can decompose and remove organic pollutants from the aqueous environment,and prepare some fine ***,they also can carry out some important reactions,such as 02 reduction reaction(ORR),O2 evolution reaction(OER),H2 evolution reaction(HER),CO2 reduction reaction(C02 RR),and N2 fixation(NRR).For catalytic reactions,it is the key to develop high-performance catalysts to meet the demand fortargeted *** recentyears,two-dimensional(2 D) materials have attracted great interest in environmental catalysis due to their unique layered structures,which offer us to make use of their electronic and structural *** progress has been made so far,including graphene,black phosphorus,oxides,layered double hydroxides(LDHs),chalcogenides,bismuth-based layered compounds,MXenes,metal organic frameworks(MOFs),covalent organic frameworks(COFs),and *** content drives us to invite many famous groups in these fields to write the roadmap on two-dimensional nanomaterials for environmental *** hope that this roadmap can give the useful guidance to researchers in future researches,and provide the research directions.

关键词： Two-dimensional materials Graphene Black phosphorus C3N4 Metal organic frameworks MXenes

TaARPC5 is required for wheat defense signaling in response to infection by the stripe rust fungus

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The Crop Journal 2022年第1期10卷 88-97页

作者： Jia Guo Huan peng Tuo Qi Sanding Xu Md Ashraful Islam Brad Day Qing ma Zhensheng Kang Jun Guo State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection Northwest A&F UniversityYangling 712100ShaanxiChina Department of Plant Soil and Microbial SciencesMichigan State UniversityEast LansingMI 48824USA

Numerous studies using a combination of confocal microscopic-and pharmacological-based approaches have demonstrated that the actin cytoskeleton dynamically responds to pathogen ***,we observed that phalloidin treatment induced actin nucleation,resulting in enhanced resistance of wheat against the stripe rust pathogen Puccinia striiformis ***(Pst).To define the mechanism underpinning this process,we characterized a family of conserved actin-binding proteins,the actin related protein(ARP)family,which controls actin ***,we identified and characterized a wheat ARPC gene(Ta ARPC5),which encodes a 136-amino acid protein containing a P16-Arc domain,the smallest subunit of the ARP2/3 *** ARPC5 m RNA accumulation was induced following the infection of plants with the avirulent Pst strain,and following the elicitation with flagellin(e.g.,flg22)as *** localization analysis revealed that Ta ARPC5 is primarily localized to the cortical actin cytoskeleton,and its precise cellular localizations suggest the proximity to processes correlated with the actin-organelle *** treatment with virulent Pst,Ta ARPC5-knockdown plants exhibited a significant reduction in the expression of PTI-specific m ***,we observed enhanced induction of reactive oxygen species(ROS)accumulation and a decrease in Ta CAT1 expression following infection with an incompatible Pst *** with yeast complementation assays,the current study demonstrates a role for Ta ARPC5 in resistance signaling in wheat against Pst infection by regulating the host actin cytoskeleton.

关键词： ARPC5 Cytoskeleton Wheat Puccinia striiformis f.sp.tritici Virus-induced gene silencing(VIGS)