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Microplastics in municipal wastewater treatment plants: a case study of Denizli/Turkey

环境科学与工程前沿(英文) 2023年第8期17卷 95-105页

作者： pelin koyuncuoğlu Gülbin Erden Environmental Engineering Department Engineering FacultyPamukkale UniversityKınıklıCampusDenizli 20160Turkey

Plastic particles smaller than 5 mm are *** are among the significant pollutants that recently attracted *** quantities of microplastics enter the sewage system daily and reach wastewater treatment plants(WWTPs).As a result,WWTPs are potential microplastic ***,they create a pathway for microplastics to reach aquatic environments with treated wastewater *** on microplastic characterization in WWTPs have gained momentum in *** study investigates the abundance,size,shape,color,polymer type,and removal efficiencies of microplastics in a municipal wastewater treatment plant(WWTP)in Denizli/*** results showed that the dominant microplastic shape in wastewater samples was fibers(41.78%–60.77%)in the 100–500μm(58.57%–80.07%)size *** of the microplastics were transparent-white(32.86%–58.93%).The dominant polymer types were polyethylene(54.05%)and polyethylene vinyl acetate(37.84%)in raw ***,the microplastic removal efficiencies of the Denizli Central WWTP as a whole and for individual treatment units were *** the microplastic pollution removal efficiency of the Denizli Central WWTP was over 95%,the microplastic concentration discharged daily into the receiving environment was considerably high(1.28×1010 MP/d).Thus,Denizli Central WWTP effluents result in a high volume of emissions in terms of microplastic pollution with a significant daily discharge to theÇürüksu Stream.

关键词： Microplastics Wastewater treatment plant Removal efficiency Daily discharge

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Microplastics in municipal wastewater treatment plants:a case study of Denizli/Turkey

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Frontiers of Environmental Science & Engineering 2023年第8期 98-108页

作者： pelin koyuncuo?lu Gulbin Erden Environmental Engineering Department Engineering FacultyPamukkale University

Plastic particles smaller than 5 mm are *** are among the significant pollutants that recently attracted *** quantities of microplastics enter the sewage system daily and reach wastewater treatment plants （WWTPs）.As a result,WWTPs are potential microplastic ***,they create a pathway for microplastics to reach aquatic environments with treated wastewater *** on microplastic characterization in WWTPs have gained momentum in *** study investigates the abundance,size,shape,color,polymer type,and removal efficiencies of microplastics in a municipal wastewater treatment plant （WWTP） in Denizli/*** results showed that the dominant microplastic shape in wastewater samples was fibers （41.78%-60.77%） in the 100-500μm （58.57%-80.07%） size *** of the microplastics were transparent-white（32.86%-58.93%）.The dominant polymer types were polyethylene （54.05%） and polyethylene vinyl acetate （37.84%） in raw ***,the microplastic removal efficiencies of the Denizli Central WWTP as a whole and for individual treatment units were *** the microplastic pollution removal efficiency of the Denizli Central WWTP was over 95%,the microplastic concentration discharged daily into the receiving environment was considerably high(1.28×1010MP/d).Thus,Denizli Central WWTP effluents result in a high volume of emissions in terms of microplastic pollution with a significant daily discharge to the?ürüksu Stream.

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Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3176-3241页

作者： pelin lu Dongxue Ruan Meiqi Huang Mi Tian Kangshun Zhu Ziqi Gan Zecong Xiao Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630PR China Department of Minimally Invasive Interventional Radiology and Laboratory of Interventional RadiologyThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260PR China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseNational Center for Respiratory MedicineDepartment of Respiratory and Critical Care MedicineGuangzhou Institute for Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120PR China Department of Stomatology Chengdu Second People's HospitalChengdu 610021PR China Hospital of Stomatology Guangdong Provincial Key Laboratory of StomatologyGuanghua School of StomatologySun Yat-sen UniversityGuangzhou 510055PR China

The applications of hydrogels have expanded significantly due to their versatile,highly tunable properties and breakthroughs in biomaterial *** this review,we cover the major achievements and the potential of hydrogels in therapeutic applications,focusing primarily on two areas:emerging cell-based therapies and promising non-cell therapeutic *** the context of cell therapy,we discuss the capacity of hydrogels to overcome the existing translational challenges faced by mainstream cell therapy paradigms,provide a detailed discussion on the advantages and principal design considerations of hydrogels for boosting the efficacy of cell therapy,as well as list specific examples of their applications in different disease *** then explore the potential of hydrogels in drug delivery,physical intervention therapies,and other non-cell therapeutic areas(e.g.,bioadhesives,artificial tissues,and biosensors),emphasizing their utility beyond mere delivery ***,we complement our discussion on the latest progress and challenges in the clinical application of hydrogels and outline future research directions,particularly in terms of integration with advanced biomanufacturing *** review aims to present a comprehensive view and critical insights into the design and selection of hydrogels for both cell therapy and noncell therapies,tailored to meet the therapeutic requirements of diverse diseases and situations.

关键词： directions overcome breakthrough

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Management of granulomatous lobular mastitis: an international multidisciplinary consensus(2021 edition)

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Military Medical Research 2022年第4期9卷 389-403页

作者： Qian-Qian Yuan Shu-Yuan Xiao Omar Farouk Yu-Tang Du Fereshte Sheybani Qing Ting Tan Sami Akbulut Kenan Cetin Afsaneh Alikhassi Rami Jalal Yaghan Irmak Durur-Subasi Fatih Altintoprak Tae Ik Eom Fatih Alper Mustafa Hasbahceci David Martínez-Ramos pelin Seher Oztekin Ava Kwong Cedric W.Pluguez-Turul Kirstyn EBrownson Shirish Chandanwale Mehran Habib Liu-Yi Lan Rui Zhou Xian-Tao Zeng Jiao Bai Jun-Wen Bai Qiong-Rong Chen Xing Chen Xiao-Ming Zha Wen-Jie Dai Zhi-Jun Dai Qin-Yu Feng Qing-Jun Gao Run-Fang Gao Bao-San Han Jin-Xuan Hou Wei Hou Hai-Ying Liao Hong luo Zheng-Ren Liu Jing-Hua lu Bin luo Xiao-Peng Ma Jun Qian Jian-Yong Qin Wei Wei Gang Wei Li-Ying Xu Hui-Chao Xue Hua-Wei Yang Wei-Ge Yang Chao-Jie Zhang Fan Zhang Guan-Xin Zhang Shao-Kun Zhang Shu-Qun Zhang Ye-Qiang Zhang Yue-Peng Zhang Sheng-Chu Zhang Dai-Wei Zhao Xiang-Min Zheng Le-Wei Zheng Gao-Ran Xu Wen-Bo Zhou Gao-Song Wu Department of Thyroid and Breast Surgery Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Pathology University of Chicago Pritzker School of MedicineChicagoIL60637USA Department of Surgical Oncology and Breast Surgery Oncology CenterFaculty of MedicineMansoura UniversityMansoura35516Egypt Department of Breast Surgery Beijing University of Chinese MedicineBeijing100700China Department of Infectious Diseases and Tropical Medicine Faculty of MedicineMashhad University of Medical SciencesMashhad***Iran Breast Department KK Women’s and Children’s Hospital100 Bukit Timah RoadSingapore229899Singapore Department of Surgery Department of Public HealthDepartment of BiostatisticsBioinformatics and Medical InformaticsInonu University Faculty of Medicine44280MalatyaTurkey Department of General Surgery Faculty of MedicineÇanakkale Onsekiz Mart University17020ÇanakkaleTurkey Department of Radiology Cancer InstituteImam Khomeini HospitalTehran University of Medical SciencesTehran***Iran Department of Surgery College of Medicine and Medical SciencesArabian Gulf University-BahrainManama26671Bahrain Department of Radiology International Faculty of MedicineIstanbul Medipol University34810IstanbulTurkey Department of General Surgery Faculty of MedicineSakarya University54050SakaryaTurkey Department of Surgery HiU Clinic170Gwongwang-roPaldal-guSuwon16488Korea Department of Radiology Faculty of MedicineAtaturk University25240ErzurumTurkey Academic Support and Education Center Hırkai Serif DistrictKececi Cesmesi StrDoktorlar BuildingB/734091IstanbulTurkey Department of General and Digestive Surgery Hospital General CastellonAvda Benicassim S/N12812004CastellónSpain Radiology Department Ankara Training and Research Hospital305018AnkaraTurkey Department of Surgery The University of Hong KongChina The University of Hong Kong-Shenzhen Hospital Shenzhen518053China University of Miami Health System and Miller School of Medicine 1475 NW 12th AvenueM

Granulomatous lobular mastitis(GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM. Literature was reviewed using PubMed from January 1, 1971 to July 31, 2020. Sixty-six international experienced multidisciplinary experts from 11 countries or regions were invited to review the *** of evidence were determined using the American College of Physicians grading system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions,etiology and predisposing factors, diagnosis criteria, treatment, clinical stages, relapse and recurrence of GLM. GLM was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stages and management algorithm for GLM to provide individual treatment strategies. In conclusion, diagnosis of GLM depends on a combination of history, clinical manifestations, imaging examinations, laboratory examinations and *** approach to treatment of GLM should be applied according to the different clinical stage of GLM. This evidencebased consensus would be valuable to assist front-line surgeons and medical specialists in the optimal management of GLM.

关键词： Granulomatous mastitis Granulomatous lobular mastitis Idiopathic granulomatous mastitis Diagnosis Treatment

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BAF和PRC2复合物亚基Dpf2和Eed拮抗调控Tbx3控制胚胎干细胞分化

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科学新闻 2020年第2期 62-62页

作者：张文胜 Constantinos Chronis 陈曦 Heyao Zhang Rapolas Spalinskas Mercedes Pardo Liangliang Chen 吴光明朱哲鑫余勇 lu Yu Jyoti Choudhary Jennifer Nichols Mana M.Parast Boris Greber pelin Sahle'n Kathrin Plath 苏州大学医学部剑桥苏大基因组资源中心 Sanger研究所马谱生物分子医学研究所伦敦癌症研究所剑桥大学干细胞研究所加州大学圣迭戈分校瑞典皇家理工学院加州大学洛杉矶分校

文章简介BAF(Brg or Brahma-associated factors)染色质重塑复合物利用其ATP酶亚基水解ATP产生的能量改变组蛋白和DNA的作用,调控转录因子同DNA的结合而调节基因的表达,参与多种生物学过程。BAF复合物由多至15个不同的亚基组成,但对这... 详细信息

文章简介BAF(Brg or Brahma-associated factors)染色质重塑复合物利用其ATP酶亚基水解ATP产生的能量改变组蛋白和DNA的作用,调控转录因子同DNA的结合而调节基因的表达,参与多种生物学过程。BAF复合物由多至15个不同的亚基组成,但对这些亚基功能的研究多局限于显示失活特定亚基而导致的表型缺陷,缺乏深入的作用机制的研究。

关键词：干细胞分化 Eed 复合物 BAF

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