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Traditional Chinese medicines for non-small cell lung cancer: Therapies and mechanisms

第25届中国控制与决策会议

作者： yang peiying TANG Jiafu YU yang State Key Laboratory of Synthetical Automation for Process Industries Northeastern University College of Information Science and Engineering Northeastern University

ISBN: (纸本)9781467355339

The model and algorithm for Vehicle Routing and Scheduling Problem （VRSP） in picking up and delivering customers to airport service were presented in this paper. VRSP is an extension of the class Vehicle Routing Problem （VRP） with more resource constraints. Mathematical models are described for the VRSP with minimizing the cost based on low carbon emissions. The Bi-directional Optimization Heuristic Algorithm （BOHA） is developed for this model. The results verified the effectiveness of the model and Algorithm. The proposed model and algorithm can provide quantitative support and help the air ticket company decision-maker develop economical, punctual shuttle service with high satisfaction.

关键词： Vehicle routing and scheduling Carbon emissions Picking up and delivering to airport service Heuristic algorithm

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Chinese Herbal Medicines 2023年第4期15卷 509-515页

作者： Fanming Kong Chaoran Wang Linlin Zhao Dongying Liao Xiaoqun Wang Binxu Sun peiying yang Yingjie Jia Department of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300381China National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin 300381China Graduate School Tianjin University of Traditional Chinese MedicineTianjin 301617China

The most common subtype of lung cancer is non-small cell lung cancer(NSCLC), which has a poor prognosis and seriously threatens the health of human beings. The multidisciplinary comprehensive treatment model has gradually become the mainstream of NSCLC treatment. Traditional Chinese medicine(TCM) can be used effectively either as an adjunctive therapy or alone throughout the NSCLC therapy,which has a significant impact on survival, quality of life, and reduction of toxicity. Therefore, this paper reviewed the theoretical basis, the latest clinical application, and combined treatment mechanisms in order to explore the advantage stage of TCM treatment and the synergistic therapeutic mechanisms.

关键词： advantage stage clinical application mechanisms non-small cell lung cancer synergistic therapeutic theoretical basis traditional Chinese medicines treatment model

The Contribution of BMI,Body Image Inflexibility,and Generalized Anxiety to Symptoms of Eating Disorders and Exercise Dependence in Exercisers

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International Journal of Mental Health Promotion 2022年第6期24卷 811-823页

作者： Liye Zou peiying yang Fabian Herold Weina Liu Attila Szabo Alyx Taylor Jing Sun Liu Ji Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education East China Normal UniversityShanghai200241China Body-Brain-Mind Laboratory School of PsychologyShenzhen UniversityShenzhen518060China Research Group Degenerative and Chronic Diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam14469Germany Institute of Health Promotion and Sports Sciences ELTE Eötvös Loránd UniversityBudapest1053Hungary School of Rehabilitation Sport and PsychologyAECC University CollegeBournemouthBH52DFUK School of Medicine and Dentistry Menzies Health Institute QueenslandGriffith UniversityParklandGold CoastQLD4222Australia

1)Background:The common factors which potentially contribute to the development of eating disorders and exercise dependence during early adulthood are still relatively *** present study aimed to examine the role of BMI,body image inflexibility,and generalized anxiety in these two behavioral problems in a sample of college students.2)Methods:In total,878 habitual exercisers(58.1%male with BMI=22.12±2.39;41.9%female with BMI=20.55±2.21)with age of 20.09±1.76 years participated in this *** main outcomes of interest are exercise dependence symptoms,eating disorders symptoms,body image inflexibility,and symptoms of generalized anxiety(as measured by Exercise Dependence Scale-Revised,Eating Disorder Examination-Questionnaire-Short Form,Body Image Acceptance and Action Questionnaire,and Generalized Anxiety Disorder-7,respectively).Pearson correlation,path analysis,and model fit information were tested.3)Results:After controlling for age,gender,and field of study,lower BMI was linked to more exercise dependence symptoms but this association was not statistically significant,while a greater BMI was significantly associated with a higher risk of developing eating disorders(β=−0.08,p<0.001).Moreover,higher body image inflexibility significantly and positively contributed to severe exercise dependence(β=0.26,p<0.001)as well as abnormal eating attitudes and behaviors(β=0.74,p<0.001).Furthermore,generalized anxiety is a significant contributor to exercise dependence symptoms(β=0.14,p<0.001)but not eating disorders symptoms.4)Conclusion:Based on our finding that body image inflexibility is a common risk factor for the development of exercise dependence and eating disorders,the prevention and treatment of these two disorders should involve the improvement of psychological *** addition,the individual with a higher BMI is more vulnerable to developing eating disorders,while those who have severer generalized anxiety symptoms should be given more attention whe

关键词： Anxiety body image BMI exercise addiction eating disorders

Clinical research linking Traditional Chinese Medicine constitution types with diseases:a literature review of 1639 observational studies

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Journal of Traditional Chinese Medicine 2020年第4期40卷 690-702页

作者： Liang Xue Wang Qi Jiang Zeqiang Li Zhuqing Zhang Mengxing yang peiying Wang Xin Wang Yanqiu Qin Yuehua Li Tianxing Zhang Tianyi Wang Yi Sun Jianxiang Li Yusi Luo Hui Li Lingru Center for Studies in Constitution Research and Reproductive Sciences of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China Institute for Tibetan Medicine China Tibetology Research CenterBeijing 100101China

OBJECTIVE:To analyze clinical studies on correlations between Traditional Chinese Medicine(TCM)body constitution types and diseases published in the past 10 years,and to provide an evidence base to support the use of such correlations for health maintenance and disease ***:We searched five databases for the period April 2009 to December 2019:China National Knowledge Infrastructure Database,Wanfang Database,China Science and Technology Journal Database,PubMed and *** types of observational studies on correlation between constitution types and diseases were included:cross-sectional,case-control and cohort *** statistical methods were employed for data ***:A total of 1639 clinical studies were identified:1452(88.59%)cross-sectional studies,115(7.02%)case-control studies and 72(4.39%)cohort studies covering 30 regions of China and five other countries(Malaysia,South Korea,Singapore,Thailand and France).The collection of studies comprised 19 disease categories and 333 different *** 10 most commonly studied diseases were hypertension,diabetes,stroke,coronary atherosclerotic heart disease(CAHD),sleep disorders,neoplasm of the breast,dysmenorrhea,fatty liver disease,chronic viral hepatitis B and *** found high distributions for each biased constitution type in different patient populations as follows:Qi-deficiency constitution in stroke,diabetes,chronic obstructive pulmonary disease,acquired immunodeficiency syndrome and hypertension;yang-deficiency constitution in female infertility,osteoporosis,irritable bowel syndrome,gonarthrosis and dysmenorrhea;Yin-deficiency constitution in hypertension,diabetes,constipation,female climacteric states and osteoporosis;phlegm-dampness constitution in hypertension,stroke,fatty liver disease,diabetes and metabolic syndrome;damp-heat constitution in acne,chronic gastritis,chronic viral hepatitis B,human papillomavirus infection and hyperuricemia;blood-stasis constit

关键词： Body constitution Medicine,Chinese traditional Clinical study Review

接送机场服务中车辆路径与调度模型的比较分析

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系统工程学报 2013年第4期28卷 529-542页

作者：杨培颖唐加福于洋东北大学流程工业综合自动化国家重点实验室信息学院系统工程研究所辽宁沈阳110819 美国西北大学工业工程与管理科学系美国芝加哥60201

针对接送机场服务中的最小碳排放量和最小成本的0-1混合整数规划模型提出了基于标签与集划分的精确算法.从顾客点地理位置分布、顾客点规模、绕行系数、车辆容量和顾客满意度五个方面对两种模型进行了比较分析.实验结果表明:两类模型的... 详细信息

针对接送机场服务中的最小碳排放量和最小成本的0-1混合整数规划模型提出了基于标签与集划分的精确算法.从顾客点地理位置分布、顾客点规模、绕行系数、车辆容量和顾客满意度五个方面对两种模型进行了比较分析.实验结果表明:两类模型的人均成本和人均耗油量都明显的体现了各自的优越性.

关键词：接送机场服务车辆路径与调度碳排放量标签算法集划分算法

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2型登革病毒04株基因组结构特点的研究

中华实验和临床病毒学杂志 1994年第1期8卷 1-6页

作者：杨佩英 Lan,SK 北京军事医学科学院微生物流行病研究所

报告了２型登革病毒０４株结构蛋白Ｃ，ＰｒＭ（Ｍ）、Ｅ和非结构蛋白ＮＳ１基因的核苷酸及氨基酸序列，并与国际参考株新几内亚Ｃ株、牙买加株和候选疫苗Ｓ１株进行了比较。结果表明，从壳体蛋白Ｃ到主要非结构蛋白ＮＳ１，这一开放读... 详细信息

报告了２型登革病毒０４株结构蛋白Ｃ，ＰｒＭ（Ｍ）、Ｅ和非结构蛋白ＮＳ１基因的核苷酸及氨基酸序列，并与国际参考株新几内亚Ｃ株、牙买加株和候选疫苗Ｓ１株进行了比较。结果表明，从壳体蛋白Ｃ到主要非结构蛋白ＮＳ１，这一开放读码框架核苷酸总数为３３８１，编码１１２７个氨基酸；在Ｅ蛋白区有３个保守的氨基酸序列，分别位于Ｅ区的９８－１１１、３７１－３７８、４１６－４２２；有２个潜在的糖基化位点，分别位于Ｅ区的Ａｓｎ－６７和Ａｓｎ－１５３位；有１２个保守的半胱氨酸残基。非结构蛋白ＮＳ１有两个糖基化位点，位于ＮＳ１区的１３０和２０７位，有１０个保守的半胱氨酸残基。在结构蛋白Ｃ、ＰｒＭ（Ｍ）、Ｅ和非结构蛋白ＮＳ１中，Ｅ蛋白表现最为保守，其次是Ｃ蛋白。Ｄ２－０４株病毒在核苷酸水平与氨基酸水平上与其他２型病毒株比较，我国０４株较类似于牙买加株，其次是ＮＧＣ株，与Ｓ１株类似性最小。说明我国病毒株与牙买加株相关性较大，与Ｓ１株相关性较小。

关键词：基因组结构登革热病毒 2型 04株

A Case Study of Global Supply Chain Risk Management

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A Case Study of Global Supply Chain Risk Management

第24届中国控制与决策会议

作者： yang peiying'' , TANG Jiafa, YAN Chongjun Department of Systems Engineering, Northeastern University, Shenyang 110004, China

Today due to the social, political and environmental pressures a lot of companies have outsourced production to oversea manufacturers, and the complexities of the chains have been mounting especially quickly. Managing risk in the supply chain has never been as challenging as it is today. In this paper a comprehensive quantitative risk evaluation and mitigation model in global supply chains is developed which from several disciplines - supply chain management, logistics, economics and international business. A case study is provided which in view of a company whose products are manufactured in China and sold in U.S. The paper identified four risks including supply risk, operational risk, demand risk and financial risk and modeled as probabilistic distributions of the outcome. Moreover, the paper implemented and integrated some risk mitigation strategies such as hedging and speculation in the simulation model for further investigation.

关键词： Supply chain management Risk management Modeling and simulation Risk mitigationn

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论农民专业合作社与农村基层组织互动发展

古今农业 2011年第1期 44-50页

作者：杨沛英陕西省社会科学院农村发展所陕西西安710065

农民专业合作社是在农村家庭承包经营基础上,适应市场经济环境下生产与流通需要的同类农产品的生产者经营者自愿联合、民主管理的互助性经济组织。但农民专业合作社发展过程中存在一些自身难以解决的问题,大多数专业性合作经济组织职能... 详细信息

农民专业合作社是在农村家庭承包经营基础上,适应市场经济环境下生产与流通需要的同类农产品的生产者经营者自愿联合、民主管理的互助性经济组织。但农民专业合作社发展过程中存在一些自身难以解决的问题,大多数专业性合作经济组织职能单一,不能适应农业生产流通服务面广、量大、综合性强、利益关系复杂的需要。因而农民专业合作社应该与地区性合作经济组织协调配合、互动发展。

关键词：专业合作社地区性合作组织互动发展

北京市西城区居民高尿酸血症患病率及其与代谢综合征关系的研究

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天津医药 2014年第7期42卷 722-724页

作者：马萍陈莉杨培颖北京市椿树社区卫生服务中心 100052

目的了解北京市西城区居民高尿酸血症(HUA)的患病情况及其与代谢综合征(MS)的关系。方法分层随机抽取834名常住居民作为调查对象,对其身高、体质量、收缩压(SBP)、舒张压(DBP)、血尿酸(UA)、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)... 详细信息

目的了解北京市西城区居民高尿酸血症(HUA)的患病情况及其与代谢综合征(MS)的关系。方法分层随机抽取834名常住居民作为调查对象,对其身高、体质量、收缩压(SBP)、舒张压(DBP)、血尿酸(UA)、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)等。根据是否患HUA分为HUA组和非HUA组。根据MS的4个组分,将调查对象分为:(1)MS0组。不具备MS组分中的任一项。(2)MS1组。具备MS组分中的一项。(3)MS2组。具备MS组分中的两项。(4)MS3组。具备MS组分的三项。(5)MS4组。具备MS组分的四项。分析HUA与MS及其组分的关系。结果调查人群HUA的患病率为12.0%,男性高于女性[21.8%(83/381)vs 3.8%(17/453),χ2=63.765,P<0.01],且各年龄段男性HUA患病率均高于女性(均P<0.05);HUA组BMI、SBP、DBP、TC、TG均高于非HUA组(均P<0.01),2组间HDL-C和FPG差异无统计学意义。HUA组分别合并超重和(或)肥胖、高血压、高血糖、血脂紊乱的患病率均高于非HUA组(均P<0.01)。HUA患病率随MS组分的增加逐渐升高(χ2=46.347,P<0.01)。结论 HUA与MS关系密切,应注重对UA水平的监测。

关键词：尿酸高尿酸血症代谢综合征患病率

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带导药系统的快速扩张器的临床研究

中华整形外科杂志 2001年第6期17卷 350-352页

作者：刘文阁杨佩瑛满中亚李素娟北京黄寺美容外科医院 100011 中国医学科学院中国协和医科大学整形外科医院滕州市中心人民医院

目的　探索快速组织扩张和提高皮瓣扩张质量的方法。方法　对 15例不同部位应用带导药 (罂粟碱 )系统的扩张器进行皮肤软组织扩张。结果　新型扩张法 (下简称NEM)和普通扩张法 (下简称GEM)扩张至额定容量所需要的平均时间分别为 2 6d和 ... 详细信息

目的　探索快速组织扩张和提高皮瓣扩张质量的方法。方法　对 15例不同部位应用带导药 (罂粟碱 )系统的扩张器进行皮肤软组织扩张。结果　新型扩张法 (下简称NEM)和普通扩张法 (下简称GEM)扩张至额定容量所需要的平均时间分别为 2 6d和 5 1d ;全部扩张完成后两种扩张法扩张器的实际注水量超过额定容量的百分比分别为 92 41%和 2 7 12 %。扩张区皮肤血流量的比较(V) ,NEM :1 2 7± 0 2 8;GEM :0 6 4± 0 11。扩张表面积即时回缩率的比较 (% ) ,NEM :2 0 17± 1 74;GEM :38 2 6± 2 0 1。结论　采用此种方法 ,扩张速度快 ,皮瓣的即时回缩率低。

关键词：皮肤软组织扩张术扩张器罂粟碱临床研究整形外科