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Developments of Cr-Si and Ni-Cr Single-Layer Thin-Film Resistors and a Bi-Layer Thin-Film Resistor with Adjustable Temperature Coefficient of Resistor

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Materials Sciences and Applications 2016年第12期7卷 895-907页

作者： Huan-Yi Cheng Ying-Chung Chen Chi-Lun li pei-jou li Mau-Phon Houng Cheng-Fu Yang Department of Electrical Engineering National Sun Yat-sen University Taiwan Institute of Microelectronics National Cheng-Kung University Taiwan Department of Chemical and Materials National University of Kaohsiung Taiwan

At first, Cr-Si (28 wt% Cr, 72 wt% Si) and Ni-Cr (80 wt% Ni, 20 wt% Cr) thin-film materials were deposited by using sputtering method at the same parameters, and their physical and electrical properties were investigated. The resistances of Cr-Si and Ni-Cr thin-film resistors decreased with the increase of deposition time (thickness) and their resistivity had no apparent variations as the deposition time increased. The temperature coefficient of resistance (TCR) of single-layer Cr-Si thin-film resistors was negative and the TCR value of single-layer Ni-Cr thin-film resistors was positive. For that, we used Cr-Si thin films as upper (or lower) layer and Ni-Cr thin films as lower (upper) layer to investigate a bi-layer thin-film structure. The deposition time of Ni-Cr thin films was fixed at 10 min and the deposition time of Cr-Si thin films was changed from 10 min to 60 min. We had found that as Cr-Si thin films were used as upper or lower layers they had similar deposition rates. We had also found that the thickness and stack method of Cr-Si thin films had large effects on the resistance and TCR values of the bi-layer thin-film resistors.

关键词： Cr-Si Ni-Cr Sputtering Method Sheet Resistance Bi-Layer Structure

Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies

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Genes & Diseases 2024年第5期11卷 315-323页

作者： Jiankun Fan Zhigang li li pei Yu Hou Institute of life Sciences Chongqing Medical UniversityChongqing 400016China Department of Hematology Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China

Hematopoiesis represents a meticulously regulated and dynamic biological *** aberrations affecting blood cells,induced by various factors,frequently give rise to hematological *** instances are often accompanied by a multitude of abnormal post-transcriptional regulatory events,including RNA alternative splicing,RNA localization,RNA degradation,and ***,post-transcriptional regulation plays a pivotal role in preserving hematopoietic *** DEAD-Box RNA helicase genes emerge as crucial post-transcriptional regulatory factors,intricately involved in sustaining normal hematopoiesis through diverse mechanisms such as RNA alternative splicing,RNA modification,and ribosome *** review consolidates the existing knowledge on the role of DEAD-box RNA helicases in regulating normal hematopoiesis and underscores the pathogenicity of mutant DEADBox RNA helicases in malignant *** is placed on elucidating both the positive and negative contributions of DEAD-box RNA helicases within the hematopoietic system.

关键词： DEAD-box RNA helicase Hemopoietic system Post-transcriptional regulation Ribosomes assembly RNA alternative splicing

Nano metal-photosensitizer based on Aza-BODIPY-Cu complex for CDT-enhanced dual phototherapy

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Chinese Chemical Letters 2024年第7期35卷 296-300页

作者： Wenjuan Jin Zelong Chen Yi Wang Jiaxuan li Jiahui li Yuxin pei Zhichao pei College of Chemistry&Pharmacy Northwest A&F UniversityYangling 712100China

Chemodynamic therapy(CDT)combined with dual phototherapy(photothermal therapy(PTT)and photodynamic therapy(PDT))is an efficient way to synergistically improve anti-tumor ***,the combination of multiple modes often makes the composition of the system more complex,which is not conducive to clinical *** this study,a dual phototherapy ligand carboxyl-modified Aza-BODIPY(BOD-COOH)and metal active center Cu^(2+)were used to construct multiple-modes metalphotosensitizer nanoparticles(BOD-Cu NPs)via one-step coordination self-assembly for combination therapy of CDT/PDT/*** order to improve delivery efficiency,the targeted hydrophilic molecule pyridinemodified glucose derivative(G-Py)was synthesized and coated onto the BOD-Cu NPs to form a glycosylated nano metal-photosensitizer BOD-Cu@G by electrostatic *** Cu^(2+)in BOD-Cu@G could not only be used as a coordination node for metal-driven self-assembly but also consume intracellular glutathione(GSH),and then catalyze Fenton-like reaction to generate hydroxyl radical(·OH)for *** vitro and in vivo studies revealed that BOD-Cu@G could achieve excellent anti-tumor efficiency by CDTenhanced dual phototherapy.

关键词： Nano metal-photosensitizer Aza-BODIPY-Cu Coordination self-assembly Chemodynamic therapy Dual phototherapy

mRNA vaccine technology for infectious diseases and beyond

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Science China life Sciences 2024年第10期67卷 2267-2270页

作者： pei Hao Xiao li Xuan li Wu Zhong Key Laboratory of Molecular Virology and Immunology Shanghai Institute of Immunity and InfectionChinese Academy of Sciences University of Chinese Academy of Sciences Changchun Veterinary Research Institute Chinese Academy of Agricultural Sciences Key Laboratory of Synthetic Biology CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy of Sciences National Engineering Research Center for the Emergency Drug Beijing Institute of Pharmacology and Toxicology

The rise of mRNA vaccine technology Vaccines stand as one of the most significant medical advancements, playing a crucial role in the prevention of infectious diseases and the improvement of global health. The triumph of smallpox vaccination stands as a towering achievement in the annals of healthcare, leading to the complete elimination of a oncedevastating disease and showcasing the efficacy of vaccination methods.

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Spacelike Framed Curves with lightlike Components and Singularities of Their Evolutes and Focal Surfaces in Minkowski 3-space

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1521-1532页

作者： Peng Cheng li Dong He pei Xin ZHAO School of Mathematics and Statistics Northeast Normal UniversityChangchun 130024P.R.China Department of Mathematics Harbin Institute of TechnologyWeihai 264209P.R.China School of Mathematics and Statistics Qingdao UniversityQingdao 266071P.R.China

In this paper,we define the evolute and focal surface of a spacelike framed curve with lightlike components in Minkowski *** is a generalization of the previous results of regular spacelike curves,since singularities are allowed in the original spacelike curves studied by spacelike framed curves with lightlike ***,we show a new geometric invariant to characterise singularities of the focal ***,the classification theorem and recognition theorem for the singularities of the focal surface in generic are also given.

关键词： Evolutes focal surfaces spacelike framed curves singularities

Long way up:rethink diseases in light of phase separation and phase transition

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Protein & Cell 2024年第7期15卷 475-492页

作者： Mingrui Ding Weifan Xu Gaofeng pei Pilong li State Key Laboratory of Membrane Biology&Frontier Research Center for Biological Structure School of Life SciencesTsinghua UniversityBeijing 100084China Tsinghua-Peking Center for life Sciences Beijing 100084China NuPhase Therapeutics Beijing 100083China

Biomolecular condensation, driven by multivalency, serves as a fundamental mechanism within cells, facilitating the formation of distinct compartments, including membraneless organelles that play essential roles in various cellular processes. Perturbations in the delicate equilibrium of condensation, whether resulting in gain or loss of phase separation, have robustly been associated with cellular dysfunction and physiological disorders. As ongoing research endeavors wholeheartedly embrace this newly acknowledged principle, a transformative shift is occurring in our comprehension of disease. Consequently, significant strides have been made in unraveling the profound relevance and potential causal connections between abnormal phase separation and various diseases. This comprehensive review presents compelling recent evidence that highlight the intricate associations between aberrant phase separation and neurodegenerative diseases, cancers, and infectious diseases. Additionally, we provide a succinct summary of current efforts and propose innovative solutions for the development of potential therapeutics to combat the pathological consequences attributed to aberrant phase separation.

关键词： multivalency compartments aberant phase separation therapeutics gain or loss of phase separation diseases

High-performance sodium storage for cobalt phosphide composite array electrodes

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Rare Metals 2024年第8期43卷 3724-3734页

作者： Man Zhang Xiao-Xu liu Tian-Yi Ji Yang li Da-Wei Sheng Shao-Dong li pei-pei Ren Ze-Xiang Shen School of Material Science and Engineering Shaanxi University of Science and TechnologyXi'an 710021China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore

Transition metal phosphides hold great potential as sodium-ion batteries anode materials owing to their high theoretical capacity and modest ***,volume changes and low intrinsic conductivity seriously largely hinder the further development of metal phosphide *** design of phosphide anode materials with reasonable structure is conducive to solving the problems of volume expansion and slow reaction kinetics during the *** this work,a composite material integrating zeolite imidazolate backbone(ZIF) and carbon materials was synthesized by the original growth ***,by the oxidation-phosphating process,CoP nanoarray composites riveted to carbon fiber(CoP@CF) were *** the CoP@CF,CoP nanoparticles are uniformly distributed on ZIF-derived carbon,reducing agglomeration and volume change during *** also provides a highly conductive network for the active material,improving the electrode ***,when evaluated as an anode for sodium-ion batteries,CoP@CF electrode displays enhanced reversible capacity(262 mAh·g^(-1) at 0.1 A·g^(-1)after 100 cycles),which is much better than that of pure CF electrode(57 mAh·g^(-1) at 0.1 A·g^(-1) after 100 cycles)prepared without the addition of *** rate performance of CoP@CF electrode is also superior to that of pure CF electrode at various current densities from 0.05 to1 A·g^(-1).The sodium storage behavior of CoP@CF was revealed by ex-situ X-ray photoelectron spectroscopy,X-ray diffraction,and synchrotron radiation absorption *** method provides a reference for the design and synthesis of anode materials in sodium-ion batteries.

关键词： Cobalt phosphide Array structure Freestanding anodes Sodium-ion batteries

Effective Ultra-High-Speed Identification Scheme of lightning Strikes Suitable for VSC-Based DC Grids

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CSEE journal of Power and Energy Systems 2024年第2期10卷 548-561页

作者： Longlong Chen Xiangyu pei Xiaoguang Wei Pengzhi li Guangfu Tang North China Electric Power University(NCEPU) Beijing 102206China Changsha University of Science and Technology Changsha 410114China State Key Laboratory of Advanced Power Transmission Technology State Grid Smart Grid Research Institute Co.Ltd.Beijing 102209China

To ensure their sound and continuous operation to the greatest extent,VSC-based DC girds have extremely stringent requirements for transmission line relay *** terms of guaranteeing their reliability,accurate identification of lightning strikes on DC transmission lines is one of the urgent key problems to be *** effective ultra-high-speed identification scheme of lightning strikes suitable for the VSC-based DC grid is proposed in this ***,an 1-mode reverse voltage traveling wave(RVTW)is constructed applying the pole-mode transformation ***,fault traveling wave propagation characteristics along the DC transmission line are analyzed in depth utilizing Peterson's ***,differences of time-frequency electromagnetic transient characteristics of 1-mode RVTWs between disturbances and faults caused by lightning strikes are distinguished in detail by means of the classical wavelet transformation multi-resolution analysis ***,extensive simulations are carried out to evaluate the performance of the proposed identification scheme,and by which its excellent rapidity,reliability and robustness are *** Terms-lightning-strike identification,Multi-resolution analysis,Relay protection,Traveling-wave protection,VsC-based DC grid,Wavelet transformation.

关键词： lightning-strike identification Multi-resolution analysis Relay protection Traveling-wave protection VsC-based DC grid Wavelet transformation

Privacy Preserving Algorithm for Spectrum Sensing in Cognitive Vehicle Networks

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Chinese journal of Electronics 2024年第1期33卷 30-42页

作者： Hongning li Tonghui HU Jiexiong CHEN Xiuqiang WU Qingqi pei Guangzhou Institute of Technology Xidian University Guangzhou CEPREI Shaanxi Key Laboratory of Blockchain and Secure Computing

The scarcity of spectrum resources fails to meet the increasing throughput demands of vehicular networks. There is an urgent need to maximize the utilization of spectrum bands in mobile networks. To ascertain the availability of spectrum bands, users should engage in wireless channel sensing and collaboration. However, spectrum sensing data always involves users’ privacy, such as their location. This paper first introduces sensing trajectory inference attack in cognitive vehicular networks and then proposes a data confusion-based privacy-preserving algorithm and a cryptonym array-based privacy-preserving aggregation scheme for spectrum sensing in cognitive vehicular networks. Unlike existing methods, the proposed schemes transmit confused data during the aggregation process. This deliberate obfuscation makes it almost impossible to infer users’ location from the transmitted data. The analysis demonstrates the resilience of the proposed schemes against sensing trajectory inference attack.

关键词： Privacy Data privacy Wireless sensor networks Authentication Data aggregation Throughput Inference algorithms