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CT灌注成像联合CT血管成像对发病12h内的急性缺血性脑卒中临床应用价值的研究

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中国血液流变学杂志 2016年第3期26卷 293-297页

作者：卢曼周赟汲晓沛王辉蔡秀英方琪苏州大学附属第一医院神经内科江苏苏州215006

目的评价CT灌注成像（CT perfusion imaging，CTP）联合CT血管成像（CT angiography,CTA）对发病12h内缺血性脑卒中的临床价值。方法对15例发病时间在12h内的脑卒中患者同时行CT平扫、CTP、CTA检查，将CTP图像通过图像工作站（***）经过... 详细信息

目的评价CT灌注成像（CT perfusion imaging，CTP）联合CT血管成像（CT angiography,CTA）对发病12h内缺血性脑卒中的临床价值。方法对15例发病时间在12h内的脑卒中患者同时行CT平扫、CTP、CTA检查，将CTP图像通过图像工作站（***）经过VPCT Neuro-STROKE进行处理，测量缺血区的脑灌注参数值并分析缺血半暗带（ischemic penumbra，IP）；通过CT血管减影（CT-DSA）模式获取头颅及颈部脑血管图像，并分析CTA结果。结果15例患者中7例患者头颅CT出现早期低密度病灶，其余8例未见明显异常；发病在4．5h之内的患者有6例，其中有5例患者经CTP显示存在缺血半暗带，另外1例患者CTP显示未见缺血半暗带，经随访证实为短暂性脑缺血发作（TIA）；发病在4．5～6h的患者有2例，其中有1例患者经CTP显示存在缺血半暗带，另外1例不存在；发病在6～12h的患者有7例，其中仅有1例经CTP显示存在缺血半暗带，其余不存在缺血半暗带。在经CTP显示存在缺血半暗带的7例患者中，梗死区的脑血流量（CBF）、脑血容量（CBV）、平均通过时间（MTT）较对侧差异均有统计学意义（P〈0．05）；缺血半暗带区的CBF、MTT较对侧差异有统计学意义（P〈0．05），CBV较对侧差异无统计学意义（P〉0．05）；缺血半暗带区的CBF、CBV及MTT较梗死区差异有统计学意义（P〈0．05）。CTA显示有14例患者存在颈内动脉（ICA）或大脑中动脉（MCA）不同程度的狭窄或完全闭塞。结论CTP联合CTA对急性缺血性脑梗死患者的诊断和治疗具有指导意义，并通过CTP判定是否存在缺血半暗带可以指导急性缺血性脑卒中的个体化治疗。

关键词： CTP CTA 急性缺血性脑卒中缺血半暗带

Evolutionary genetics of wheat mitochondrial genomes

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The Crop Journal 2023年第6期11卷 1774-1781页

作者： hui-Lin Hu Fan Zhang pei wang Fu-Hao Lu State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004HenanChina Henan Key Laboratory of Big Data Analysis and Processing School of Computer and Information EngineeringHenan UniversityKaifeng 475004HenanChina School of Mathematics and Statistics Henan UniversityKaifeng 475004HenanChina

The Triticum-Aegilops complex provides ideal models for the study of polyploidization,and mitochondrial genomes(mtDNA)can be used to trace cytoplasmic inheritance and energy production following *** this study,gapless mitochondrial genomes for 19 accessions of five Triticum or Aegilops species were *** genomics confirmed that the BB-genome progenitor donated mtDNA to tetraploid ***(genome formula AABB),and that this mtDNA was then passed on to the hexaploid ***(AABBDD).T urartu(AA)was the paternal parent of ***(AAGG),and an earlier ***(DD)was the maternal parent of ***(CCDD).Genic sequences were highly conserved within species,but frequent rearrangements and nuclear or chloroplast DNA insertions occurred during *** highly variable mitochondrial genes(atp6,cob,nad6,and nad9)were established as marker genes for Triticum and Aegilops species *** BB/GG-specific atp6 and cob genes,which were imported from the nuclear genome,could facilitate identification of their diploid *** haplotypes and repeat-sequence patterns indicated that BB was much closer to GG than to ***(SS).These findings provide novel insights into the polyploid evolution of the Triticum/Aegilops complex from the perspective of mtDNA,advancing understanding of energy supply and adaptation in wheat species。

关键词： Wheat Mitochondrion mtDNA Comparative genomics Polyploidization

Anti-follower jamming wide gap multi-pattern frequency hopping communication method

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Defence Technology（防务技术） 2020年第2期16卷 453-459页

作者： Yao-bei wang Hou-de Quan hui-xian Sun pei-zhang Cui Department of Electronic and Optical Engineering Army Engineering UniversityShijiazhuang 050003China National Key Laboratory of Science and Technology on Communications University of Electronic Science and Technology of ChinaChengdu 611731China

This paper deals with the follower jamming(FJ)resistance for the frequency hopping(FH)communication system over additive white Gaussian noise(AWGN)*** FH systems are susceptible to be jammed by FJ,and multi-pattern frequency hopping(MPFH)has good resistance to *** further improve the FJ rejection capability of MPFH,we propose a wide gap multi-pattern frequency hopping(WGMPFH)*** uses channels to represent messages,and the data channel and complementary channel are hopping on orthogonal frequency slots according to wide gap FH *** transmitted signal lures FJ to aim at the data channel and the complementary channel is away from FJ by adopting wide gap frequency *** does not affect the complementary channel but increases the signal energy in the data channel,thus the effect of FJ is *** bit error rate(BER)is derived under FJ and the effects of three FJ parameters(tracking success probability,jamming duration ratio and jamming bandwidth ratio)on the BER performance of WGMPFH are investigated versus the co nventional FH/BFSK and MPFH *** and simulation results show that when under the worst-case FJ,the proposed WGMPFH outperforms the MPFH by about 1-3 dB and outperforms the conventional FH/BFSK by more than 4 *** proposed WGMPFH shows superior jamming rejection performance under FJ especially in severe signal-to-jamming ratio(SJR).

关键词： Frequency hopping communication Multi-pattern frequency hopping Follower jamming AWGN channel

Graph Partitioning Method to Determine Servers Placement in CDN

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Journal of Harbin Institute of Technology(New Series) 2013年第2期20卷 61-68页

作者： An-Yu Zhou hui-Qiang wang pei-You Song College of Computer Science and Technology Harbin Engineering University Network and Education Technology Center Harbin University of Commerce Dept. of Computer Science University of New Mexico

To determine CDN cache servers'placement reasonably,an idea that using graph partitioning to solve the problem was put forward through theoretical analysis and the specific algorithm of partitioning was researched. The concept of graph partitioning for CDN was defined. The conditions of graph partitioning for CDN were demonstrated: the sum of the weights of the nodes in each subarea is as close as possible; edge cut between the subareas is as large as possible; internal nodes in each subarea are connected as far as possible. By reference to light vertex matching algorithm of graph partitioning for network simulation,a multilevel k-way algorithm of graph partitioning for CDN was proposed. The maximized edge cut k-way KL refinement algorithm was discussed. Graph partitioning is a feasible way to solve the problem of CDN servers'placement. Multilevel k-way algorithm is a feasible algorithm for CDN graph partitioning.

关键词： graph partitioning CDN servers placement matching algorithm

Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer’s disease

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Cellular & Molecular Immunology 2019年第11期16卷 892-894页

作者： pei-pei Guan Xin Yu Yan-hui Zou Pu wang College of Life and Health Sciences Northeastern University110819 ShenyangPR China Institute of Health Science China Medical University110122 ShengyangPR China

Alzheimer’s disease(AD)is generally believed to be caused by the production ofβ-amyloid protein(Aβ),and hyperphosphorylation of tau,which are deposited inβ-amyloid plaques(APs)and neurofibrillary tangles(NFTs),***,the inherent reasons for their propagation and deposition remain *** light of our prior works,magnesium(Mg2+)deficiency is critical for the onset of AD.1 In addition,the restoration of Mg2+in the brain reduces neuroinflammation by suppressing the expression of interleukin(IL)-1β,1 which decreases Aβoverload in an APH-1α/1β-dependent mechanism.2 In this regard,inflammation is the target of Mg2+in the treatment of *** addition to IL-1β,a powerful inflammatory inducer,cyclooxygenase-2(COX-2),has also been reported to be inhibited by the addition of Mg2+.3 We thereby extended our prior works to *** of the underlying mechanisms elucidated the role of COX-2 in spreading Aβdeposits in APs to the *** was probably caused by the formation of hetero-oligomers between COX-2 and Aβ,which have been shown to accelerate the aggregation and deposition of Aβin APs.4 Moreover,the induction of COX-2 decreased the glycosylation of tau,which has been shown to result in the phosphorylation of tau in different animal *** this scenario,the status of tau phosphorylation is critical for the development and progression of AD.5 Therefore,COX-2 appears to be a potential therapeutic target for AD.

关键词： amyloid inflammation inhibited

Control of Equiaxed Crystal Ratio of High Carbon Steel Billets by Circular Seam Cooling Nozzle

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Journal of Iron and Steel Research International 2011年第2期18卷 24-30页

作者： LI pei-song LU Jun-hui QIU Sheng-tao wang Zhong-ying ZHAO pei Northeastern University Shenyang 110004 Liaoning China State Key Laboratory of Advanced Steel Processing and Products Central Iron and Steel Research Institute Beijing 100081 China

A circular seam cooling nozzle and its online control system have been developed to reduce the center segregation in high carbon steel billets by decreasing the superheat of the molten steel and improving the equiaxed crystal ratio based on the numerical results. An industrial experiment has been carried out on a 150 mm× 150 mm caster to investigate the effect of the circular seam cooling nozzle on the superheat removal of the molten steel. The results show that the circular seam cooling nozzle can be used to control the casting temperature in a closed loop control system. The online control system can be effectively adapted to the variation of operating parameters. The casting lasts about 4 h and about 400 t steel is successfully produced in a continuous operation. The removal of about 14 ℃ superheat and the improvement of approximate 10% equiaxed crystal ratio can be achieved by the newly developed circular seam cooling nozzle.

关键词： circular seam cooling nozzle high equiaxed crystal ratio billet low superheat

A New Caffeoylquiniclactone, Neochlorgeniclatone from the Leaves of Betula platyphylla Suk.

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Chinese Chemical Letters 2001年第6期12卷 509-510页

作者： Su Juan wang Yue Hu pei hui Ming HUA Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110015

A new caffeoylquiniclactone, named neochlorgeniclatone, was isolated from the leaves of Betula platyphylla Suk. The Structure was established by spectroscopic data.

关键词： Neochlorgeniclatone Betula platyphylla Suk. leaves

A New Monoterpene Glucoside from the Leaves of Betula platyphylla Suk.

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Chinese Chemical Letters 2001年第4期12卷 343-344页

作者： Su Juan wang Yue Hu pei hui Ming HUA Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110015

A new monoterpene glucoside. (2E,67.)-2.6-dimethyl-8-beta -D-glucosyloxy-2,6-octadienoic acid, was isolated from the leaves of Betula platyphylla Suk. The structure was established by spectroscopic data.

关键词： Betula platyphylla Suk. monoterpene glucoside leaves.

Effects of UV-B radiation intensity and timing on epidemiological components of wheat stripe rust

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Journal of Integrative Agriculture 2018年第12期17卷 2704-2713页

作者： wang hui QIN Feng CHENG pei MA Zhan-hong wang Hai-guang Department of Plant Pathology China Agricultural UniversityBeijing 100193P.R.China Rizhao Agricultural Bureau of Shandong Province Rizhao 276800P.R.China

Stripe rust caused by Puccinia striiformis f. sp. tritici is an important wheat disease worldwide that is greatly influenced by environmental conditions. Ultraviolet B(UV-B) radiation is one important environmental factor affecting the occurrence and epidemiology of wheat stripe rust. Investigating UV-B radiation effects on the epidemiology of stripe rust may be conducive to monitoring and predicting this disease. In this study, wheat seedlings were exposed to UV-B radiation during different periods under laboratory conditions and radiation effects on epidemiological components of wheat stripe rust were investigated. Results showed that incubation period was shortened, and the infection efficiency, sporulation quantity and disease index increased when UV-B radiation was performed only pre-inoculation. When the UV-B radiation was performed only postinoculation or both pre-and post-inoculation, the incubation period was prolonged, and the infection efficiency, sporulation quantity and disease index were reduced. When healthy wheat seedlings were inoculated using urediospores collected from wheat leaves irradiated by UV-B only post-inoculation or both pre-and post-inoculation, infection efficiency, sporulation quantity and disease index were also reduced. However, in the latter, the disease incubation period did not differ under varying UV-B radiation intensities compared to that when wheat leaves were not treated with UV-B radiation. Overall, the effects of direct exposure of wheat plants to UV-B radiation with different intensities in different periods on epidemiological components of wheat stripe rust were systematically explored, and the results suggest that the effects of UV-B radiation increased gradually with the increase of UV-B radiation intensity. This information provides a basis for monitoring and predicting this disease as well as for conducting further studies on pathogen virulence variation.

关键词： wheat stripe rust UV-B radiation epidemiological component Puccinia striiformis f.sp.tritici