检索结果-南通市图书馆

Deep Learning Blockchain Integration Framework for Ureteropelvic Junction Obstruction Diagnosis Using Ultrasound Images

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tsinghua Science and Technology 2024年第1期29卷 1-12页

作者： Yu guan Pengceng wen Jianqiang Li Jinli Zhang Xianghui Xie Faculty of Information Technology Beijing University of TechnologyBeijing 100124China Beijing Children’s Hospital Affiliated to Capital Medical University Beijing 100020China

UreteroPelvic Junction Obstruction(UPJO)is a common hydronephrosis disease in children that can result in an even progressive loss of renal *** is an economical,radiationless,noninvasive,and high noise preliminary diagnostic step for *** intelligence has been widely applied to medical fields and can greatly assist doctors'diagnostic *** demand for a highly secure network environment in transferring electronic medical data online,therefore,has led to the development of blockchain *** this study,we built and tested a framework that integrates a deep learning diagnosis model with blockchain *** diagnosis model is a combination of an attention-based pyramid semantic segmentation network and a discrete wavelet transformation-processed residual classification *** also compared the performance between benchmark models and our *** diagnosis model outperformed benchmarks on the segmentation task and classification task with MloU=87.93,MPA=93.52,and accuracy=91.77%.For the blockchain system,we applied the InterPlanetary File System protocol to build a secure and private sharing *** framework can automatically grade the severity of UPJO using ultrasound images,guarantee secure medical data sharing,assist in doctors'diagnostic ability,relieve patients'burden,and provide technical support for future federated learning and linkage of the Internet of Medical Things(loMT).

关键词： data mining image processing and computer vision machine learning medical information systems

Mechanistic research:Selenium regulates virulence factors,reducing adhesion ability and inflammatory damage of Helicobacter pylori

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第1期30卷 91-107页

作者： Chun Qin Gan-Rong Huang Ai-Xing guan wen-Ting Zhou Hao Chen pei-pei Luo Xian-Ke Luo Yan-Qiang Huang Zan-Song Huang guangxi Technology Innovation Cooperation Base of Prevention and Control Pathogenic Microbes with Drug Resistance Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Digestive Diseases Affiliated Hospital of Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Key Laboratory of the Prevention and Treatment of Drug Resistant Microbial Infecting Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Pathology Wannan Medical CollegeWuhu 241002Anhui ProvinceChina Department of Gastroenterology Wujin People’s Hospital affiliated to Jiangsu UniversityChangzhou 213004Jiangsu ProvinceChina Department of Gastroenterology Guangzhou Liwan District People's HospitalGuangzhou 510370Guangdong ProvinceChina

BACKGROUND The pathogenicity of Helicobacter pylori is dependent on factors including the environment and the *** selenium is closely related to pathogenicity as an environmental factor,the specific correlation between them remains *** To investigate how selenium acts on virulence factors and reduces their *** *** strains were induced by sodium *** expression of cytotoxin-associated protein A(CagA)and vacuolating cytotoxin gene A(VacA)was determined by quantitative PCR and Western *** was used to analyze CagA,CagM,CagE,Cag1,Cag3,and CagT.C57BL/6A mice were infected with the attenuated strains subjected to sodium selenite induction,and *** colonization,inflammatory reactions,and the cell adhesion ability of *** were *** CagA and VacA expression was upregulated at first and then downregulated in the *** strains after sodium selenite *** expression was significantly and steadily downregulated after the 5th cycle(10 d).Transcriptome analysis revealed that sodium selenite altered the levels affect *** virulence factors such as CagA,CagM,CagE,Cag1,Cag3,and *** these factors,CagM and CagE expression was continuously downregulated and further downregulated after 2 h of induction with sodium ***,CagT expression was upregulated before the 3rd cycle(6 d)and significantly downregulated after the 5th ***1 and Cag3 expression was upregulated and downregulated,respectively,but no significant change was observed by the 5th cycle.C57BL/6A mice were infected with the attenuated strains subjected to sodium selenite *** extent of *** colonization in the stomach increased;however,sodium selenite also induced a mild inflammatory reaction in the gastric mucosa of ***-infected mice,and the cell adhesion ability of *** was significantly *** These results demonstrate that *** displayed virulence attenuation after

关键词： Helicobacter pylori Sodium selenite Virulence factors Adherence Inflammation

Realizing the excellent oxidation resistance of an environmental barrier coating through aluminum surface modification

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2024年第7期13卷 976-986页

作者： Lin Dong wen-Qi Yang Lin Chen guan-Jun Yang Chang-Jiu Li State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China Xi’an Aerospace Engine Company Limited in China Aerospace Science and Technology Corporation Xi’an 710065China

The lifetime of Si-based environmental barrier coatings(EBCs)is constrained by thermally grown SiO_(2)oxidelayer(SiO_(2)-TGO),which can cause premature cracking and *** address this issue,a new approach for surfacemodification using aluminum is *** oxidation performance was examined in a 50 vol%H_(2)O-50 vol%O_(2)environment at 1350℃for up to 300 *** results indicate that a dense ytterbium aluminum garnet(YbAG)layer wasformed after modification,decreasing the porosity by 80%.Due to the elimination of fast diffusion channels and the lowoxygen permeability of YbAG,aluminum modification significantly reduced the growth rate of SiO_(2)-TGO by nearly twoorders of ***,its thickness decreased by more than 70%after 300 h of exposure.A diffusioncontrolled oxidation mechanism indicates that the modified dense surface is equivalent to an initial SiO_(2)layer with a specificthickness,causing a shift in the oxidation time and increasing the oxidation *** research provides valuableinsights for designing Si-based EBC with improved lifetimes.

关键词： environmental barrier coating(EBC) oxidation modification diffusion cracking

Durable dual-state duplex Si-HfO_(2)with excellent oxidation and cracking resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2024年第3期13卷 388-401页

作者： Lin Chen Jing-Chuan Luo wen-Qi Yang Chang-Jiu Li guan-Jun Yang State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China Xi’an Aerospace Engine Company Limited in CASC Xi’an 710065China

The lifetime of Si bond coatings in environmental barrier coatings is constrained by phase-transition-induced cracking of the SiO_(2)*** this study,Si-HfO_(2)dual-state duplex composite materials are proposed to address this issue by partially forming HfSiO_(4)and minimizing the SiO_(2)*** as-prepared composite exhibited a structure comprising discrete HfO_(2)“bricks”embedded in a continuous Si“mortar”,while the oxidized state transformed into discrete HfSiO_(4)“bricks”within continuous thin SiO_(2)“mortars”.The results indicate that continuous thin SiO_(2)contributes to reducing the oxidation rate to a level comparable to that of pure Si,and discrete HfSiO_(4)particles aid in relieving phase transition-induced stress and inhibiting crack propagation,thereby enhancing oxidation and cracking resistance ***,the composite with 20 mol%HfO_(2)and a mean particle size of~500 nm at 1370℃exhibited a service lifetime 10 times greater than that of pure *** research provides valuable insights for designing Si-based bond coatings with improved service lifetime.

关键词： oxidation environmental barrier coatings(EBCs) phase transition cracking bond coatings

AIoT for Aircraft Final Assembly:An Intelligent and Collaborative Framework

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Communications and Information Networks 2024年第3期9卷 262-276页

作者： Cheng Ren Xiaojing wen Xinping guan Cailian Chen Yehan Ma Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of System Control and Information Processing Ministry of Education of ChinaShanghai 200240China Shanghai Engineering Research Center of Intelligent Control and Management Shanghai 200240China School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Aircraft final assembly line(AFAL)involves thousands of processes that must be completed before ***,the heavy reliance on manual labor in most assembly processes affects the quality and prolongs the delivery *** the advent of artificial intelligence of things(AIoT)technologies has introduced advancements in certain AFAL scenarios,systematically enhancing the intelligence level of the AFAL and promoting the widespread deployment of artificial intelligence(AI)technologies remain significant *** address these challenges,we propose the intelligent and collaborative aircraft assembly(ICAA)framework,which integrates AI technologies within a cloud-edge-terminal *** ICAA framework is designed to support AI-enabled applications in the AFAL,with the goal of improving assembly efficiency at both individual and multiple process *** analyze specific demands across various assembly scenarios and introduce corresponding AI technologies to meet these *** three-tier ICAA framework consists of the assembly field,edge data platform,and assembly cloud platform,facilitating the collection of heterogeneous terminal data and the deployment of AI *** framework enhances assembly efficiency by reducing reliance on manual labor for individual processes and fostering collaboration across multiple *** provide detailed descriptions of how AI functions at each level of the ***,we apply the ICAA framework to a real AFAL,focusing explicitly on the flight control system testing *** practical implementation demonstrates the effectiveness of the framework in improving assembly efficiency and promoting the adoption of AIoT technologies.

关键词： intelligent aircraft final assembly line AIoT cloud-edge-terminal framework design

Strong metal-support interaction between AuPd nanoparticles and oxygen-rich defect ZrO_(2) for enhanced catalytic 5-hydroxymethylfurfural oxidation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第2期35卷 507-511页

作者： Yunlei Zhang Yiran Liu wen guan Mengxue Cao Yao Chen Pengwei Huo Institute of Green Chemistry and Chemical Technology School of Chemistry and Chemical EngineeringJiangsu UniversityZhenjiang 212013China School of the Environment and Safety Jiangsu UniversityZhenjiang 212013China

The unique properties of metal oxide surfaces,crystal surfaces and defects play vital roles in biomass upgrading *** this work,hierarchical porous bowl-shaped ZrO_(2)(HB-ZrO_(2))with mixed crystal phase was designed and employed as the support for loading AuPd bimetal with different proportions to synthesize AuPd/HB-ZrO_(2) *** effects of surface chemistry,oxygen defects,bimetal interaction and metal-support interaction of AuPd/HB-ZrO_(2) on catalytic performance for the selective oxidation of 5-hydroxymethylfurfural(HMF)to 2,5-furandicarboxylic acid(FDCA)were systematically *** Au 2 Pd1/HB-ZrO_(2) catalyst afforded a satisfactory FDCA yield of 99.9%from HMF oxidation using O_(2) as the oxidant in water,accompanied with an excellent FDCA productivity at 97.6 mmol g^(−1) h^(−1).This work offers fresh insights into rationally designing efficient catalysts with oxygen-rich defects for the catalytic upgrading of biomass platform chemicals.

关键词： 5-Hydroxymethylfurfural oxidation 2,5-Furandicarboxylic acid Oxygen-rich defect ZrO_(2) AuPd bimetal Bowl-shaped structure

In-plane isotropic separator-induced highly efficient sodium plating for unlocking the fast-charging capability of anode-free sodium battery at practical conditions

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Materiomics 2024年第3期10卷 643-651页

作者： Haocheng Yuan Kaihua wen Shundong guan Ying Liang Yu-Hsien Wu Sijie Liu Dengfeng Yu Liangliang Li Ce-wen Nan State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China

Ether-based electrolytes with excellent reductive stability are compatible with sodium(Na)metal an-odes,which enables stable cycling for Na metal batteries even in an anode-free ***,the practical applications of anode-free sodium batteries(AFSBs)with a high theoretical energy density are restricted by the low-rate capability and limited cycle *** we demonstrate that the mechanical properties of the separators,which have been overlooked in previous studies,can significantly affect the cycling stability of AFSBs due to the intrinsic softness of Na and the large volume variation of AFSBs during Na plating/*** using various separators including polypropylene(PP),polyethylene(PE),PP/PE/PP tri-layer,and aluminum oxide-coated separators,we find that the balanced elastic moduli of the separator along the machine direction and transverse direction are crucial for enabling highly effi-cient Na plating and unlocking the 4 C fast-charging capability of the AFSBs at practical conditions including a high cathode active mass loading(13.5 mg/cm^(2)),lean electrolyte addition(8.8 mL/cm^(2)),and no pre-sodiation *** study provides an important separator design principle for the develop-ment of high-rate and long-cycle-life AFSBs.

关键词： Sodium metal Elastic modulus Ether electrolyte Sodium battery Short circuit

Removal of rubidium from brine by an integrated film of sulfonated polysulfone/graphene/potassium copper ferricyanide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第5期69卷 112-121页

作者： Huanxi Xu peihua Lin pei-Jun Liu Hai-Gang Liu Hui-Bin Guo Chao-Xiang Wu Ming Fang Xu Zhang guan-Ping Jin Anhui Province Engineering Research Center of Flexible and Intelligent Materials School of Chemistry and Chemical EngineeringHefei University of TechnologyHefei 230009China Chemical Design and Research Institute Co. LTD of Qinghai ProvinceQinghai Engineering and Technology Research Center of Fine ChemicalXining 810008China

A novel integrated film of sulfonated polysulfone/graphene/potassium copper ferricyanide(KCuFC/SPSG)was used for selectively extracting rubidium ion(Rb^(+))from *** form KCuFC/SPSG,the precursor film of sulfonated polysulfone/graphene(SPSG)was synthesized by phase conversion process,which was alternately immersed in 0.1 mol·L^(-1)CuSO_(4)/K_(4)[Fe(CN)_(6)]by in-situ adsorption coupled co-precipitation *** data such as nuclear magnetic resonance spectrometer,Fourier transform infrared spectroscope,X-ray photoelectron spectroscope,X-ray diffraction,scanning electron microscope,and energy dispersive spectroscopy all verified that abundant KCuFC were uniformly located on the *** resulting KCuFC/SPSG was used in film separation *** the solution was fed into the system,the Rb^(+)could be selectively adsorption by KCuFC/*** the saturation adsorption,0.5 mol·L^(-1)NH_(4)Cl/HCl was fed into the film cell,Rb^(+)could be quickly desorbed by ion-exchange between Rb^(+)and NH_(4)^(+)in the lattice of *** purpose of separating and recovering Rb^(+)from the brine can be achieved after the repeated *** effects of pH,adsorption time,and interferential ions on the adsorption capacity of Rb^(+)were investigated by batch *** adsorption behavior fits the pseudo-second order kinetic process,while KCuFC has a higher adsorption capacity(Langmuir maximum sorption 165.4 mg·g^(-1)).In addition,KCuFC/SPSG shows excellent selectivity for Rb^(+)even in complex brine ***/SPSG could maintain 93.5%extraction efficiency after five adsorption/desorption cycles.

关键词： Rubidium extraction Potassium copper ferricyanide Sulfonated polysulfone Graphene oxide Adsorption

Protein tyrosine phosphatases:emerging role in cancer therapy resistance

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cancer Communications 2024年第6期44卷 637-653页

作者： Min Zhao wen Shuai Zehao Su Ping Xu Aoxue Wang Qiu Sun guan Wang Innovation Center of Nursing Research Nursing Key Laboratory of Sichuan ProvinceDepartment of BiotherapyCancer Center and State Key Laboratory of BiotherapyNational Clinical Research Center for GeriatricsWest China HospitalWest China School of NursingSichuan UniversityChengduSichuanP.R.China West China Biomedical Big Data Center Med-X Center for InformaticsSichuan UniversityChengduSichuanP.R.China Emergency Department Zigong Fourth People’s HospitalChengduSichuanP.R.China

Background:Tyrosine phosphorylation of intracellular proteins is a posttranslational modification that plays a regulatory role in signal transduction during cellular *** of signal transduction proteins caused by protein tyrosine phosphatases(PTPs)contributed their role as a convergent node to mediate cross-talk between signaling *** the context of cancer,PTP-mediated pathways have been identified as signaling hubs that enabled cancer cells to mitigate stress induced by clinical *** is achieved by the promotion of constitutive activation of growth-stimulatory signaling pathways or modulation of the immune-suppressive tumor *** evidences suggested that anticancer drugs will release their greatest therapeutic potency when combined with PTP inhibitors,reversing drug resistance that was responsible for clinical failures during cancer *** covered:This review aimed to elaborate recent insights that supported the involvement of PTP-mediated pathways in the development of resistance to targeted therapy and immune-checkpoint *** opinion:This review proposed the notion of PTP inhibition in anticancer combination therapy as a potential strategy in clinic to achieve long-term tumor *** clinical trials are currently underway to assess the safety and efficacy of combination therapy in advanced-stage tumors.

关键词： cancer treatment combination therapy drug resistance protein tyrosine phosphatase