检索结果-南通市图书馆

Chinese, Pakistani media interview CPAFFC President on 20th CPC National Congress

在线全文

学校读者我要写书评

暂无评论

Voice of Friendship 2022年第4期 16-18页

作者： pei Xingchen 不详

On Nov 10,lin Songtian,president of the Chinese People’s Association for Friendship with Foreign Countries,held a news conference at the Chinese embassy in *** was interviewed by five Chinese media outlets—Xinhua News Agency,China Radio International,Economic Daily News,China Economic Net and Phoenix TV—along with 15Pakistani media outlets,including Pakistan Broadcasting Corp,Pakistan Television Corp,the Associated Press of Pakistan,Dawn,the Express Tribune and Pakistan Observer.

关键词： interview media Pakistan

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华多椎鰕虎鱼仔稚鱼的形态特征

动物学报 2006年第3期52卷 585-590页

作者：林昭进梁沛文中国水产科学研究院南海水产研究所广州510300

1999-2005年间,在珠江口收集到了189尾中华多椎虎鱼的仔稚鱼,获得了各个不同发育阶段的个体,采用动态追踪法进行鉴定。其鉴别特征为:仔鱼期鱼体细长,消化道长,肛前长占体长的三分之二强,腹腔上方有一椭圆形鳔泡,肌节数52-53(30-32+20-... 详细信息

1999-2005年间,在珠江口收集到了189尾中华多椎虎鱼的仔稚鱼,获得了各个不同发育阶段的个体,采用动态追踪法进行鉴定。其鉴别特征为:仔鱼期鱼体细长,消化道长,肛前长占体长的三分之二强,腹腔上方有一椭圆形鳔泡,肌节数52-53(30-32+20-22),全身仅在尾部下方有一黑色素斑。稚鱼期鳍条数已定,可根据背、臀鳍的位置和鳍条数以及肌节数鉴定。在发育过程中,仔鱼体长由5.0mm到10.0mm的阶段,体型发生了一定变化,肛前长与体长的比例由0.78倍缩小到0.68倍,第2背鳍与臀鳍基长的比例由2.60倍缩小到1.86倍,此后处于稳定的状态。稚鱼体长达21.0mm时头部开始变态,吻部及眼睑的皮质增厚,前鼻孔突出,至体长26.0mm时形成鼻管,眼睛出现一定程度的退化,眼径变小。中华多椎虎鱼仔稚鱼出现于5、8、9和11月份,分布于珠江口西侧河道的出海口。对该种形态特征与相似种的区别及产卵期进行了讨论。

关键词：中华多椎鰕虎鱼仔稚鱼形态特征生态习性珠江口

在线全文

学校读者我要写书评

暂无评论

基于小波变换与遗传算法的混合多用户检测

电路与系统学报 2006年第2期11卷 94-98,93页

作者：林丽莉仇佩亮浙江工商大学信息与电子工程学院浙江杭州310035 浙江大学信息与电子工程系浙江杭州310027

本文将遗传算法与作者先前提出的小波多用户检测器相结合,提出一种基于小波变换与遗传算法的混合多用户检测方案。采用遗传算法对小波多用户检测器的输出进行优化,降低误比特率,提高系统抗远近干扰的能力。仿真结果表明,只需进行3到5次... 详细信息

本文将遗传算法与作者先前提出的小波多用户检测器相结合,提出一种基于小波变换与遗传算法的混合多用户检测方案。采用遗传算法对小波多用户检测器的输出进行优化,降低误比特率,提高系统抗远近干扰的能力。仿真结果表明,只需进行3到5次遗传进化,该混合多用户检测器便能取得很好的检测性能,与其他将遗传算法用于多用户检测的方案相比,大大缩减了遗传算法的运行时间,更加有利于实时实现。

关键词：多用户检测遗传算法小波变换远近效应

高等级中心城市生产性服务输出空间特征——基于广州商务服务企业行为的探讨

在线全文

学校读者我要写书评

暂无评论

地理研究 2010年第12期29卷 2166-2178页

作者：钟韵闫小培林彰平暨南大学特区港澳经济研究所广州510632 中山大学城市与区域研究中心广州510275 广州大学发展研究院广州510405 广州大学地理科学学院广州510405

根据对企业的调查及访谈,从服务范围、服务流向以及服务强度三方面,以广州为例分析高等级中心地的生产性服务输出空间模式。总结出区别于传统服务业的生产性服务输出新特点:中心地的服务范围跳出了单个城市体系的区域,且并不完全遵循城... 详细信息

根据对企业的调查及访谈,从服务范围、服务流向以及服务强度三方面,以广州为例分析高等级中心地的生产性服务输出空间模式。总结出区别于传统服务业的生产性服务输出新特点:中心地的服务范围跳出了单个城市体系的区域,且并不完全遵循城市等级而扩散;服务流向不单从高等级城市流向低等级城市,更多的是在高等级城市之间流动;服务销量与客户量的空间分布不一致。基于企业行为的解释,提出服务经济时代下高等级中心城市生产性服务输出的几点启示:服务提供者与消费者之间的空间距离对生产性服务输出的影响较小,生产性服务输出的服务范围上限可以设定为服务提供者的影响力所能辐射的最远距离;高等级中心地的生产性服务的输出流向反映出城市参与全国乃至全球城市分工的职能与定位;在城市等级的分析中,服务强度应与服务范围同时作为判断中心地等级的指标;生产性服务输出的研究将有助于分析区域间的产业关联及区域联系。

关键词：生产性服务服务输出中心地企业行为

Artificial pulmonary surfactant as a carrier for intratracheally instilled insulin

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2007年第5期28卷 744-750页

作者： Ying JI,Chen LIU,Yuan-ying pei~2Department of Pharmaceuties,School of Pharmacy,Fudan University,Shanghai 200032,China Department of Pharmaceutics School of Pharmacy Fudan University Shanghai China

Aim:The relative bioavailabilities and effects on lung injury alleviation of 4 insu-lin-artificial pulmonary surfactant (INS-APS) preparations were studied in *** relationship between the minimal surface tension (γmin) of INS-APS andthe absorption of insulin was also ***:Four formulations ofAPS[1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)/lecithin/palmitic acid(PA),DPPC/1-hexadecanol (Hex)/tyloxapol (Tyl),DPPC/L-α-phosphatidyl-DL-glyc-erol sodium salt (PG),DPPC/Tyl]were prepared by thin-film sonication methodand direct *** γminof 4 APS dispersions was examined with andwithout INS by pulsating with a bubble surface *** vivo experimentswere performed in which serum glucose change and the insulin level were mea-sured by an enzymatic glucose reagent kit and a radioimmunology assay kit afterIT to *** reduction in lung injury by INS-APS following 7 d of consecutiveadministration was evaluated by the pulmonary edema index (the weight ratio ofwet lung to dry lung) and histopathology ***:The γminof allAPS dispersions were below 10 mN/*** was no significant difference (P>0.05) between the γ(min)of APS and the corresponding *** vivo experi-ments showed a significant glucose level decrease and insulin absorptionincrease (Plin solution *** the results,we found that the pulmonary edema index values of all the INS-APS groups were significant lower (Plin solution group,and there were no significant differences (P>0.05) between INS/DPPC/Tyl,INS/DPPC/PG,and the control *** pulmonary edema indices and histopatho-logical observation indicated that INS-APS could alleviate lung ***:The most potent hypoglycemic effect and insulin absorption increase in this studywere obtained with INS/DPPC/*** to the results,there was a linearcorrelation between the γminand relative bioavailability of INS-

关键词： pulmonary drug delivery system pharmacokinetics pharmacodynamics hypoglycemic effect minimal surface tension absorption pulmonary edema index histopathology examination

In vitro studies of polyethyleneimine coated miRNA microspheres as anticancer agents

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2016年第6期9卷 1609-1617页

作者： Irena Rytblat Ning Wu Huangli Xu Aharon Gedanken Xiukun lin Bar-Ilan Institute for Nanotechnology and Advanced Materials Department of Chemistry Bar-Ilan University Ramat-Gan 52900 Israel Key Laboratory of Experimental Marine Biology Institute of Oceanology Chinese Academy of Sciences Qingdao 26607 I China Department of Pharmacology Capital Medical University Beijing 100069 China

RNA plays important roles as a gene-silencing agent, a therapeutic agent for clinical treatment, and in the differentiation, proliferation, and development of cells. However, RNA is very difficult to work with due to its sensitivity and fragility. Another obstacle in using RNA for gene delivery/silencing is its negative charge, which causes its repulsion by cell membranes, which are also negatively charged. Our recent study showed that miR-125b is upregulated in glioblastoma （GMB） and plays an oncogenic role in GMB cells by promoting cell proliferation and inhibiting apoptosis. Endogenous miR-125b can be blocked by transfection of its antisense RNA molecule, miR-125b antisense （miR-125b-AS）. Thus, miR- 125b-AS can be developed as an RNA-based agent for cancer treatment. However, instability during storage and difficulty in delivery into cells has limited the use of RNA-based therapies thus far. In the current work, we demonstrate a short and simple one-step technique for the preparation of positively charged RNA nanospheres （miR-125b-RNS and miR-125b-AS-RNS） coated with a bioavailable polymer, polyethylenimine （pei）. These RNA nanospheres are able to penetrate the cell directly without the use of liposomes. Our study confirmed that converting miR-125b and miR-125b-AS into nanospheres is a viable approach for storing RNA. In addition, this study provides evidence that pei-coated RNA nanospheres have the potential to be used as a novel class of anticancer a^ents.

关键词： nanospheres gene silencing gene delivery polyethylenimine anticancer agents

Effect of miR-296 on the Apoptosis of Androgen-independent Prostate Cancer Cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Reproduction and Contraception 2009年第1期20卷 1-10页

作者： pei CHENG Run-sheng LI Biao-yang lin Wei-qun WANG Yu-hua LI Yan GUO Wei LI Institute for Systems Biomedicine Shanghai Jiao Tong University Shanghai 200240 China Shanghai Institute of Planned Parenthood Research Shanghai 200032 China Zhejiang California International NanoSystems Institute Hangzhou 310029 China

Objective To investigate the miR-296＇s function in prostate carcinoma（PCa） cells. Methods In order to profile the miRNA expression in LNCaP cells, the cultured cells were stimulated with androgen after 48-h starvation, miRNA microarray analysis and Q-RT-PCR assay were performed. To characterize the effects of miR296 on PCa cells, CL-1 and PC-3 cells were transfected with miR-296 and antisense-miR-296, cell growth and apoptosis were then analyzed. Results The miR-296-5p expression was up-regulated by 2.22 folds in the CL-1 cells, which do not express significantly androgen receptor, than in LNCaP cells. Knockdown of miR-296-5p induced apoptosis of CL-1 cells, but not LNCaP cells. However, knockdown of miR-296-5p inhibited the growth rate of LNCaP cells cultured in absence of androgen. Conclusion MiR-296-5p could be important for development of prostate cancer from androgen dependence to androgen independence.

关键词： prostate cancer cells miR-296-5p apoptosis

基于记忆细胞剪切和非线性资源分配的人工免疫识别系统

在线全文

学校读者我要写书评

暂无评论

模式识别与人工智能 2013年第4期26卷 374-381页

作者：邓泽林谭冠政何锫中南大学信息科学与工程学院长沙410083 长沙理工大学计算机与通信工程学院长沙410076

为减少人工免疫识别系统(AIRS)的记忆细胞数量并提高AIRS的分类准确率,提出一种基于记忆细胞剪切和非线性资源分配的人工免疫识别系统(PNAIRS).PNAIRS采用样本属性离散化来压缩训练空间,利用记忆细胞剪切来淘汰低适应度细胞,并使用非线... 详细信息

为减少人工免疫识别系统(AIRS)的记忆细胞数量并提高AIRS的分类准确率,提出一种基于记忆细胞剪切和非线性资源分配的人工免疫识别系统(PNAIRS).PNAIRS采用样本属性离散化来压缩训练空间,利用记忆细胞剪切来淘汰低适应度细胞,并使用非线性资源分配来优化分类器.PNAIRS对6个UCI数据集进行分类测试,测试结果与其它分类算法结果对比,显示PNAIRS具有较小规模的记忆细胞群体和较高的分类准确率,而且算法运行速度快.这表明PNAIRS算法是一个性能良好的分类算法,具有潜在的应用价值.

关键词：人工免疫识别系统(AIRS) 记忆细胞剪切非线性资源分配

Floating-gate photosensitive synaptic transistors with tunable functions for neuromorphic computing

在线全文

学校读者我要写书评

暂无评论

Science China Materials 2021年第5期64卷 1219-1229页

作者： lingkai Li Xiao-lin Wang Junxiang pei Wen-Jun Liu Xiaohan Wu David Wei Zhang Shi-Jin Ding State Key Laboratory of ASIC and System School of MicroelectronicsFudan UniversityShanghai 200433China

Synaptic devices that merge memory and processing functions into one unit have broad application potentials in neuromorphic computing, soft robots, and humanmachine interfaces. However, most previously reported synaptic devices exhibit fixed performance once been fabricated,which limits their application in diverse scenarios. Here, we report floating-gate photosensitive synaptic transistors with charge-trapping perovskite quantum dots(PQDs) and atomic layer deposited(ALD) Al_(2)O_(3) tunneling layers, which exhibit typical synaptic behaviors including excitatory postsynaptic current(EPSC), pair-pulse facilitation and dynamic filtering characteristics under both electrical or optical signal stimulation. Further, the combination of the high-quality Al2O3 tuning layer and highly photosensitive PQDs charge-trapping layer provides the devices with extensively tunable synaptic performance under optical and electrical co-modulation. Applying light during electrical modulation can significantly improve both the synaptic weight changes and the nonlinearity of weight updates, while the memory effect under light modulation can be obviously adjusted by the gate *** pattern learning and forgetting processes for "0" and "1"with different synaptic weights and memory times are further demonstrated in the device array. Overall, this work provides synaptic devices with tunable functions for building complex and robust artificial neural networks.

关键词： synaptic device floating-gate transistor perovskite quantum dot tunable synaptic function optical and electrical comodulation