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Ultrastructure and phylogeny of Ustilago coicis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第4期14卷 336-345页

作者： Jing-ze ZHANG pei-gang GUAN gang TAO Mohammad Reza OJAGHIAN Kevin David HYDE Institute of Biotechnology College of Agriculture and BiotechnologyZhejiang University Guizhou Institute of Plant Protection Key Laboratory of Systematic Mycology and Lichenology Institute of MicrobiologyChinese Academy of Sciences Institutue of Excellence in Fungal Research School of ScienceMae Fah Luang University

Ustilago coicis causes serious smut on Coix lacryma-jobi in Dayang Town,Jinyun County,Zhejiang Province of *** this paper,ultrastructural assessments on fungus-host interactions and teliospore development are presented,and molecular phylogenetic analyses have been done to elucidate the phylogenetic placement of the *** growth within infected tissues was both intracellular and intercellular and on the surface of fungus-host interaction,and the fungal cell wall and the invaginated host plasma membrane were separated by a sheath comprising two distinct layers between the fungal cell wall and the invaginated host plasma *** development of teliospore walls was unique as they appeared to be originated from the *** addition,internal transcribed spacer(ITS) and large subunit(LSU) sequence data showed that *** is closely related to Ustilago trichophora which infects grass species of the genus Echinochloa(Poaceae).

关键词： Fungus-host interaction Molecular phylogenetics Smut Teliospore wall development

Thermal performance evaluation of subcritical organic Rankine cycle for waste heat recovery from sinter annular cooler

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Journal of Iron and Steel Research International 2020年第3期27卷 248-258页

作者： Jun-sheng Feng Guang-tao Gao Yousef NDabwan gang pei Hui Dong School of Environment and Energy Engineering Anhui Jianzhu UniversityHefei 230026AnhuiChina School of Engineering and Science University of Science and Technology of ChinaHefei 230026AnhuiChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina

The sinter cooling flue gas expelled from the end of an annular cooler was taken as the heat source of an organic Rankine cycle(ORC)system,and R123,R245fa,R600,R601 and R601a were selected as the working fluids of the ORC *** effects of evaporation temperature and superheat degree of working fluid,as well as the pinch point temperature difference in the evaporator on the system thermal performance,were analyzed in *** results show that the system net output power and exergy efficiency for different working fluids first increase and then decrease with an increase in the evaporation temperature and decrease with an increase in the superheat degree and pinch point temperature *** change in pinch point temperature difference has no effect on the system thermal *** a given operational condition,the system thermal efficiency and exergy efficiency of R 123 are the maximum,while the system total irreversible loss of R245fa is the *** the evaporation temperature is greater than 110°C,the system net output power of R600 is the *** ORC system could obtain the maximum net output power and exergy efficiency through the adjustment of evaporation temperature of working fluid.

关键词： Sinter Waste heat recovery Organic Rankine cycle Fluid selection Performance evaluation

Single-cell RNA sequencing to understand host-virus interactions

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Virologica Sinica 2024年第1期39卷 1-8页

作者： Jia-Tong Chang Li-Bo Liu pei-gang Wang Jing An Department of Microbiology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China

Single-cell RNA sequencing(scRNA-seq)has allowed for the profiling of host and virus transcripts and host-virus interactions at single-cell *** review summarizes the existing scRNA-seq technologies together with their strengths and *** applications of scRNA-seq in various virological studies are discussed in depth,which broaden the understanding of the immune atlas,host-virus interactions,and immune ***-seq can be widely used for virology in the near future to better understand the pathogenic mechanisms and discover more effective therapeutic strategies.

关键词： Single-cell RNA sequencing(scRNA-seq) Host-virus interaction COVID-19 Flavivirus

Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer's tau pathology

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Signal Transduction and Targeted Therapy 2022年第7期7卷 2545-2554页

作者： Shichao Huang Zhen Zhang Junwei Cao Yongchun Yu gang pei State Key Laboratory of Cell Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of Sciences200031 ShanghaiChina Institutes of Brain Science State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain ScienceFudan University200032 ShanghaiChina Shanghai Key Laboratory of Signaling and Disease Research Laboratory of Receptor-based BiomedicineThe Collaborative Innovation Center for Brain ScienceSchool of Life Sciences and TechnologyTongji UniversityShanghaiChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina

The apolipoprotein E4(APOE4)genotype is one of the strongest genetic risk factors for Alzheimer’s disease(AD),and is generally believed to cause widespread pathological alterations in various types of brain ***,we developed a novel engineering method of creating the chimeric human cerebral organoids(chCOs)to assess the differential roles of APOE4 in neurons and ***,the astrogenic factors NFIB and SOX9 were introduced into induced pluripotent stem cells(iPSCs)to accelerate the induction of *** the above induced iPSCs were mixed and cocultured with noninfected iPSCs under the standard culturing condition of cerebral *** anticipated,the functional astrocytes were detected as early as 45 days,and it helped more neurons matured in chCOs in comparation of the control human cerebral organoids(hCOs).More interestingly,this method enabled us to generate chCOs containing neurons and astrocytes with different genotypes,namely APOE3 or ***,it was found in chCOs that astrocytic APOE4 already significantly promoted lipid droplet formation and cholesterol accumulation in neurons while both astrocytic and neuronal APOE4 contributed to the maximum *** notably,we observed that the cooccurrence of astrocytic and neuronal APOE4 were required to elevate neuronal phosphorylated tau levels in chCOs while Aβlevels were increased in chCOs with neuronal ***,our results not only revealed the essence of both neuronal and astrocytic APOE4 for tau pathology,but also suggested chCOs as a valuable pathological model for AD research and drug discovery.

关键词： cerebral alterations neuronal

Numerical simulation on recrystallization behavior and microstructure evolution during hot continuous rolling process of 38CrMoAl steel rod

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Journal of Iron and Steel Research International 2022年第10期29卷 1633-1645页

作者： Fei Li Li-wen Zhang Chi Zhang Kang-jie Song pei-gang Mao School of Materials Science and Engineering Dalian University of TechnologyDalian116024LiaoningChina

The control of microstructure during hot rolling process of steel is of great importance and will affect the properties of the steel *** to the production line,a three-dimensional multi-field coupled finite element model of 24-pass continuous hot rolling process of 38CrMoAl steel rod is established using the finite element software *** on the recrystallization kinetics model and the grain growth model,a subroutine written in Fortran is introduced to calculate the recrystallization behavior and microstructure evolution of 38CrMoAl steel during the entire rolling *** distribution and evolution of variables such as strain,temperature and recrystallization fractions during the rolling process are *** temperature variations and grain sizes at both the center and surface of the tested steel are compared with the experimental *** it is found that the simulation results are in good agreement with the experimental ones,confirming the reliability of the established model.

关键词： 38CrMoAl steel Recrystallization Microstructure evolution Hot rolling process Numerical simulation

NUMERICAL INVESTIGATION ON THE HYDRODYNAMIC PERFORMANCES OF A NEW SPAR CONCEPT

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Journal of Hydrodynamics 2007年第4期19卷 473-481页

作者： ZHANG Fan YANG Jian-min LI Run-pei CHEN gang State Key Laboratory of Ocean Engineering Shanghai Jiaotong University Shanghai 200030 China

Recently, the spar platform concept develops quickly in the offshore oil and gas exploitations, especially in deep and ultra-deep water, owing to its benign motion performance, excellent stability and adaptation to wide range of water depth. Many new spar concepts have been put forward with the purpose of reducing fabrication difficulty and cost, while meeting the requirements of exploitation in the meantime Based on the aims mentioned above, a new spar concept was presented in this article and its hydrodynamics both in operating and survival conditions was studied by means of numerical simulation. Basic model tests were also conducted to calibrate the numerical approach. Following aspects are highlighted：（1） new spar concept, （2） global performance of the spar concept and （3） mooring line analysis.

关键词： spar platform time-domain coupled analysis hydrodynamic performances

COUPLING EFFECTS FOR CELL-TRUSS SPAR PLATFORM: COMPARISON OF FREQUENCY-AND TIME-DOMAIN ANALYSES WITH MODEL TESTS

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Journal of Hydrodynamics 2008年第4期20卷 424-432页

作者： ZHANG Fan YANG Jian-min LI Run-pei CHEN gang State Key Laboratory of Ocean Engineering Shanghai Jiaotong University Shanghai 200030 China

For the floating structures in deepwater, the coupling effects of the mooring lines and risers on the motion responses of the structures become increasingly significant. Viscous damping, inertial mass, current loading and restoring, etc. from these slender structures should be carefully handled to accurately predict the motion responses and line tensions. For the spar platforms, coupling the mooring system and riser with the vessel motion typically results in a reduction in extreme motion responses. This article presents numerical simulations and model tests on a new cell-truss spar platform in the State Key Laboratory of Ocean Engineering in Shanghai Jiaotong University. Results from three calculation methods, including frequency-domain analysis, time-domain semi-coupled and fully-coupled analyses, were compared with the experimental data to find the applicability of different approaches. Proposals for the improvement of numerical calculations and experimental technique were tabled as well.

关键词： cell-truss spar time-domain coupled analysis model test coupling effects

Numerical study of PV/T-SAHP system

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第7期9卷 970-980页

作者： gang pei Jie JI Ke-liang LIU Han-feng HE Ai-guo JIANG Department of Thermal Science and Energy Engineering University of Science and Technology of China Hefei 230027 China

In order to utilize solar energy effectively and to achieve a higher electrical efficiency by limiting the operating temperature of the photovoltaic （PV） panel, a novel photovoltaic/thermal solar-assisted heat pump （PV/T-SAHP） system was proposed and constructed. The hybrid solar system generates electricity and thermal energy simultaneously. A distributed parameters model of the PWT-SAHP system was developed and applied to analyze the system dynamic performance in terms of PV action, photothermal action and Rankine cycle processes. The simulation results indicated that the coefficient of performance （COP） of the proposed PV/T-SAHP can be much better than that of the conventional heat pump. Both PV-efficiency and photothermic efficiency have been improved considerably. The results also showed that the performance of this PV/T-SAHP system was strongly influenced by the evaporator area, tube pitch and tilt angle of the PV/T evaporator, which are the key factors in PV/T-SAHP system optimization and PV/T evaporator design.

关键词： Photovoltaic (PV) Photothermic Heat pump Photovoltaic/thermal (PV/T) evaporator

New Hybrid CHP System Integrating Solar Energy and Exhaust Heat Thermochemical Synergistic Conversion with Dual-Source Energy Storage

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Journal of Thermal Science 2024年第3期33卷 970-984页

作者： QIN Yuanlong LIU Taixiu LI peijing ZHAO Kai JIAO Fan pei gang LIU Qibin Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230027China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China School of Energy Power and Mechanical EngineeringNorth China Electric Power UniversityBeijing102206China

For the efficient use of solar and fuels and to improve the supply-demand matching performance in combined heat and power(CHP)systems,this paper proposes a hybrid solar/methanol energy system integrating solar/exhaust thermochemical and thermal energy *** proposed system includes parabolic trough solar collectors(PTSC),a thermochemical reactor,an internal combustion engine(ICE),and hybrid storage of thermal and chemical energy,which uses solar energy and methanol fuel as input and outputs power and *** methanol thermochemical decomposition reaction,mid-and-low temperature solar heat and exhaust heat are upgraded to chemical energy for efficient power *** thermal energy storage(TES)stores surplus thermal energy,acting as a backup source to produce heat without emitting CO_(2).Due to the energy storage,time-varying solar energy can be used steadily and efficiently;considerable supply-demand mismatches can be avoided,and the operational flexibility is *** the design condition,the overall energy efficiency,exergy efficiency,and net solar-to-electric efficiency achieve 72.09%,37.65%,and 24.63%,*** fuel saving rate(FSR)and the CO_(2) emission reduction(ER_(CO_(2)))achieve 32.97%and 25.33%,*** research findings provide a promising approach for the efficient and flexible use of solar energy and fuels for combined heat and power.

关键词： hybrid energy system solar thermochemical exhaust heat energy storage operational flexibility