检索结果-南通市图书馆

Nutritional supplements use in high-performance athletes is related with lower nutritional inadequacy from food

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2016年第3期5卷 368-374页

作者： Mónica Sousa Maria J.Fernandes pedro Carvalho José Soares pedro moreira Vitor Hugo Teixeira Centre of Research Education Innovation and Intervention in Sport Faculty of Sport University of Porto Faculty of Nutrition and Food Sciences University of Porto Research Centre on Physical Activity Health and Leisure Faculty of Sport University of Porto

Background: The use of nutritional supplements(NS) among athletes is widespread. However, little is known about the relationship between nutritional adequacy and NS usage. The aims of this study were to evaluate the NS usage and to compare the nutritional intake from food and prevalence of micronutrient inadequacy(PMI) between NS users and ***: Portuguese athletes from 13 sports completed an NS usage questionnaire and a semi-quantitative food-frequency questionnaire assessing information over the previous 12 months. The estimated average requirement cut-point method was used to calculate PMI. General linear models were used to compare nutritional intake and NS usage. Chi-squared tests and logistic regression were performed to study, respectively,relationships and associations between PMI and NS ***: From the 244 athletes(66% males, 13–37 years), 64% reported NS usage. After adjustment, NS users showed a higher intake from food(p < 0.05), for at least 1 gender, for energy, and for 7 of the 17 studied nutrients. The highest PMI were seen for vitamins D and E, calcium, folate,and magnesium. After adjustment, NS users, irrespective of gender, reported lower PMI for calcium(OR = 0.28, 95%CI: 0.12–0.65), and female users for magnesium(OR = 0.06, 95%CI: 0.00–0.98).Conclusion: Athletes using NS reported a higher nutritional intake from food, and a lower PMI for several nutrients. Perhaps, those who were taking NS were probably the ones who would least benefit from it.

关键词： Carbohydrates Minerals Proteins Sport Vitamins

Influence of the Dissipative Contact Models on the Dynamic Response of Multibody Systems

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文B版） 2011年第6期1卷 828-837页

作者： pedro moreira Paulo Flores J.C. Pimenta Claro Hamid Lankarani CT2M/Department of Mechanical Engineering University of Minho Campus de Azur~m Guimar6es 4800-058 Portugal Department of Mechanical Engineering Wichita State University Wichita KS 67260-133 USA

Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第31期28卷 4310-4327页

作者： pedro Moutinho-Ribeiro Ines A Batista Sofia T Quintas Bárbara Adem Marco Silva Rui Morais Armando Peixoto Rosa Coelho pedro Costa-moreira Renato Medas Susana Lopes Filipe Vilas-Boas Manuela Baptista Diogo Dias-Silva Ana L Esteves Filipa Martins Joanne Lopes Helena Barroca Fátima Carneiro Guilherme Macedo Sonia A Melo Serviço de Gastrenterologia Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal Faculty of Medicine University of PortoPorto 4200Portugal Instituto de Investigacao e Inovacao em Saúde(i3S) Universidade do PortoPorto 4200Portugal IPATIMUP-Institute of Molecular Pathology and Immunology University of PortoPorto 4200Portugal Instituto de Ciencias Biomédicas Abel Salazar(ICBAS) University of PortoPorto 4050Portugal Servico de Cirurgia Geral Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal Unidade de Saúde Familiar Serpa Pinto ACeS Porto OcidentalPorto 4250Portugal Serviço de Anatomia Patológica Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal

BACKGROUND Individuals within specific risk groups for pancreatic ductal adenocarcinoma(PDAC)[mucinous cystic lesions(MCLs),hereditary risk(HR),and new-late onset diabetes mellitus(NLOD)]represent an opportunity for early cancer *** ultrasound(EUS)is a premium image modality for PDAC screening and precursor lesion *** no specific biomarker is currently clinically available for this purpose,glypican-1(GPC1)is overexpressed in the circulating exosomes(crExos)of patients with PDAC compared with healthy subjects or those harboring benign pancreatic *** To evaluate the capacity of GPC1+crExos to identify individuals at higher risk within these specific groups,all characterized by *** This cross-sectional study with a prospective unicentric cohort included 88 subjects:40 patients with MCL,20 individuals with HR,and 20 patients with NLOD.A control group(CG)was submitted to EUS for other reasons than pancreatic pathology,with normal pancreas and absence of hereditary risk factors(n=8).The inclusion period was between October 2016 and January 2019,and the study was approved by the Ethics Committee of Centro Hospitalar Universitário de São João,Porto,*** patients provided written informed *** and blood tests for quantification of GPC1+crExos by flow cytometry and carbohydrate antigen 19-9(CA 19-9)levels by ELISA were performed in all ***-guided tissue acquisition was done whenever *** statistical analysis,SPSS®27.0(IBM Corp.,Armonk,NY,United States)version was *** graphs were created using GraphPad Prism 7.00(GraphPad Software,San Diego,CA,United States).RESULTS Half of MCLs harbored worrisome features(WF)or high-risk stigmata(HRS).Pancreatic abnormalities were detected by EUS in 10.0%and 35.0%in HR and NLOD individuals,respectively,all considered non-malignant and“harmless.”Median levels of GPC1+crExos were statistically different:MCL[99.4%,interquartile range(IQR):94.9%-99.8%],HR(8

关键词： Glypican-1 Circulating exosomes Endoscopic ultrasound Pancreatic cancer risk groups Pancreatic cancer precursor lesions Genetic predisposition

Pathogenesis and clinical management of Helicobacter pylori gastric infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2019年第37期25卷 5578-5589页

作者： Breno Bittencourt de Brito Filipe Ant?nio Fran?a da Silva Aline Silva Soares Vinícius Afonso Pereira Maria Luísa Cordeiro Santos Mariana Miranda Sampaio pedro Henrique moreira Neves Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da Bahia

Helicobacter pylori(***)is a gram-negative bacterium that infects approximately 4.4 billion individuals ***,its prevalence varies among different geographic areas,and is influenced by several *** infection can be acquired by means of oral-oral or fecal-oral transmission,and the pathogen possesses various mechanisms that improve its capacity of mobility,adherence and manipulation of the gastric microenvironment,making possible the colonization of an organ with a highly acidic *** addition,*** presents a large variety of virulence factors that improve its pathogenicity,of which we highlight cytotoxin associated antigen A,vacuolating cytotoxin,duodenal ulcer promoting gene A protein,outer inflammatory protein and gamma-glutamyl *** host immune system,mainly by means of a Th1-polarized response,also plays a crucial role in the infection *** most ***-positive individuals remain asymptomatic,the infection predisposes the development of various clinical conditions as peptic ulcers,gastric adenocarcinomas and mucosa-associated lymphoid tissue *** and non-invasive diagnostic methods,each of them with their related advantages and limitations,have been applied in *** ***,bacterial resistance to antimicrobial therapy is a major challenge in the treatment of this infection,and new therapy alternatives are being tested to improve *** *** but not least,the development of effective vaccines against *** infection have been the aim of several research studies.

关键词： Helicobacter pylori Virulence factors Immune response Antibiotics Vaccines

Brain scarring in infants:immunological insights from a neonatal hypoxic-ischemic encephalopathy model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2909-2910页

作者： pedro Moreno Pimentel-Coelho Carlos Chagas Filho Biophysics Institute Federal University of Rio de JaneiroRio de JaneiroBrazil

Neonatal hypoxic-ischemic encephalopathy(HIE)is a significant cause of disability in *** brain function and accelerating neurological recovery may require a combination of neuroprotective and pro-regenerative treatments at different stages of *** the first hours after the neonatal insult are the most critical period for neuroprotection,the existence of secondary and tertiary mechanisms of brain injury offers the possibility of preventing delayed neurodegeneration in the subsequent days,weeks,or months(Levison et al.,2022).

关键词： neonatal protective hypoxic

Bubble Dynamics and Heat Transfer on Biphilic Surfaces:Experiments and Numerical Simulation

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2020年第4期17卷 809-821页

作者： pedro Pontes Ricardo Cautela Emanuele Teodori Ana Sofia Moita Anastasios Georgoulas António Luís Nobre moreira moreira IN+-Center for Innovation Technology and Policy ResearchDepartment of Mechanical EngineeringInstituto Superior TécnicoUniversidade de LisboaAv.Rovisco Pais1049-001 LisboaPortugal ASML Holding N.V. De Run 65015504 DRVeldhovenThe Netherlands Department of Exact Sciences and Engineering Portuguese Military AcademyR.Gomes Freire2031169-203 LisboaPortugal Advanced Engineering Centre School of ComputingEngineering and MathematicsCockcroft BuildingLewes RoadUniversity of Brighton BN24GJUK

Wettability is known to play a major role in enhancing pool boiling heat *** this context bioinspired surfaces can bring significant advantages in pool boiling *** work addresses a numerical investigation of bubble growth and detachment on a biphilic surface pattern,namely in a superhydrophobic region surrounded by a hydrophilic *** characteristics resemble bioinspired solutions explored in our research group,mainly considering the main topographical *** numerical approach is intended to provide additional information to an experimental approach,allowing to obtain temperature,pressure and velocity fields in and around the bubble,which help to describe bubble *** model was validated based on experimental data obtained with extensive image processing of synchronized high-speed video and high-speed thermographic *** results obtained here clearly evidence that combining enhanced direct numerical simulations with high-resolution transient experimental measurements is a promising tool to describe the complex and intricate hydrodynamic and heat transfer phenomena governing pool boiling on heated biphilic surfaces.

关键词： bioinspired biphilic surfaces bubble dynamics two-phase heat transfer time resolved infrared thermography CFD model

Idiopathic sudden sensorineural hearing loss:Effectiveness of salvage treatment with low-dose intratympanic dexamethasone

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Otology 2021年第1期16卷 6-11页

作者： pedro Salvador Francisco moreira da Silva Rui Fonseca Department of Otorhinolaryngology Hospital Senhora da OliveiraGuimaraesPortugal

Objectives:To evaluate hearing outcome of salvage treatment with intratympanic steroids(ITS)in idiopathic sudden sensorineural hearing loss(ISSNHL)refractory to initial systemic steroid(SS)*** and methods:A retrospective medical chart review was conducted on 54 consecutive patients with ISSNHL refractory to *** treatment with a low dose intratympanic dexamethasone(4 mg/ml)was offered after one week of primary *** were divided into two groups:25 patients accepted ITS(treatment group)and 29 patients did not undergo additional treatment(control group).A pure tone average(PTA)gain of at least 10 dB was considered hearing ***:Hearing improvement rate was higher in ITS group compared to control group(40%vs.13.8%,p=0.035).A mean PTA improvement of 8.6±9.8 dB was observed in the ITS group and,whereas the control group had an average hearing gain of 0.7±2 dB(p<0.001).Audiometric analysis revealed a significant hearing gain in ITS group at all tested frequencies compared to control group(p<0.05).Analysis of the selected variables,identified intratympanic steroid treatment as the only independent prognostic factor for hearing improvement(OR=4.2,95%CI:1.1e15.7;p=0.04).Conclusion:Intratympanic low dose dexamethasone is effective in patients with incomplete hearing recovery after primary systemic steroid treatment.

关键词： Intratympanic Steroids Salvage Sudden sensorineural hearing loss Idiopathic

Species composition and diversity of woody communities along an elevational gradient in tropical Dwarf Cloud Forest

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2021年第6期18卷 1489-1503页

作者： Breno moreira pedro Manuel VILLA Carlos Mariano ALVEZ-VALLES Fabricio Alvim CARVALHO Botanical Garden Federal University of Juiz de ForaJuiz de Fora36045-500Brazil Department of Forest Engineering Federal University of ViçosaViçosa36570-900Brazil Department of Veterinary Medicine National University Major of San MarcosPucallpa25001Peru Departament of Botany Federal University of Juiz de ForaJuiz de Fora36036-900 Brazil

Elucidating woody community diversity and structure change along environmental gradients is still a central issue of tropical forest ecology. We have evaluated changes in alpha and beta diversity, community composition and structure of woody communities along an elevational gradient in Dwarf Cloud Forests, Southeast Brazil. We selected five areas along an elevational gradient(1,300-1,600 m asl), and randomly allocated 10 plots(10 m × 20 m) in each area in the Ibitipoca State Park(ISP), Serra da Mantiqueira, southeastern Brazil. All woody species(diameter at breast height ≥ 5.0 cm) were collected for taxonomic identification. Thus, we analysed the woody communities based on a phytosociological approach. Overall, 147 species and 37 families were recorded, distributed in 2,303 individuals. No differences in the species richness pattern were observed between areas using the rarefaction and extrapolation curves. Significant differences in species composition and structure between areas were observed. The high beta diversity observed, corroborated by the Jaccard coefficient, increases with decreasing altitude. Our results showed that woody communities in the studied Dwarf Cloud Forests have a higher diversity and structural variability along elevational gradient.

关键词： Atlantic Forest Forest structure Ibitipoca State Park Serra da Mantiqueira

Application of Bioinspired Superhydrophobic Surfaces in Two-phase Heat Transfer Experiments

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2017年第3期14卷 506-519页

作者： Emanuele Teodori Ana Sofia Moita Miguel Moura pedro Pontes Antonio moreira Yuan Bai Xinlin Li Yan Liu IN+- Center for Innovation Technology and Policy Research Instituto Superior T~enico Universidade de Lisboa Av. Rovisco Pais 1049-001 Lisboa Portuga Key Laboratory of Bionic Engineering (Ministry of Education) Jilin University Changchun 130022 China

This paper addresses the potential to use Lotus leafbioinspired surfaces in applications involving heat transfer with phase change, namely pool boiling and spray impingement. Besides describing the role of bioinspired topographical features, using an innovative technique combining high-speed visualization and time-resolved infrared thermography, surface durability is also addressed. Water is used for pool boiling and for spray impingement systems （simplified as single droplet impact）, while HFE7000 is used in a pool boiling cooler for electronic components. Results show that surface durability is quickly compro- mised for water pool boiling applications, as the chemical treatment does not withstand high temperatures （T 〉 100 ℃） during long time intervals （3 h - 4 h）. For HFE7000 pool boiling （depicting lower saturation temperature - 34 ℃）, heat transfer en- hancement is governed by the topography. The regular hierarchical pattern of the bioinspired surfaces promotes the heat transfer coefficient to increase up to 22.2%, when compared to smooth surfaces, while allowing good control of the interaction mechanisms until a distance between micro-structures of 300 gm- 400 Ixm. Droplet impingement was studied for surface temperatures ranging between 60 ℃ - 100 ℃. The results do not support the use of superhydrophobic surfaces for cooling applications, but reveal great potential for other applications involving droplet impact on heated surfaces （e.g. metallurgy in- dustry）.

关键词： bioinspired surfaces surface micro-patterning two-phase heat transfer time resolved infrared thermography