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Clean Energy 2024年第3期8卷 34-47页

作者： Jhon Jairo Pérez Luis Hernando Correa Poul AlbergØstergaard pedro cabrera Universidad de La Salle-Engineering Faculty Electrical DepartmentCampus La CandelariaBogota D.C.Colombia Aalborg University Department of PlanningRendsburggade 149000 AalborgDenmark University of Las Palmas de Gran Canaria Department of Mechanical EngineeringCampus Universitario de TafiraLas Palmas de Gran CanariaSpain

Colombia aims to boost the utilization of mass transportation systems in its major cities while simultaneously reducing greenhouse gas emissions by 20%,in alignment with the commitments of the COP21 *** 2020,the transport sector in Colombia accounted for 34.4%of the country’s energy demand and was responsible for~49%of its total CO_(2) *** article presents an assessment of energy consumption,environmental effects and the fuel costs of Bogotá’s bus rapid transit system based on the Activity,Share,Intensity,Fuel methodology.A long-term analysis spanning from 2021 to 2040 was developed using the long-range energy alternatives planning *** conduct this assessment,the tool was calibrated using data from 2019 and *** distinct scenarios based on energy policies implemented in Bogotáwere examined:Business as Usual,Fast Transition,High Growth and Low *** energy consumption and environmental effects,the results underscore the pivotal role of diversifying energy sources and reducing reliance on fossil fuels such as ***,the analysis emphasizes the urgent need to accelerate the transition to alternative energy sources such as natural gas and electricity.

关键词： ASIF energy consumption environmental effects LEAP long-term energy model public transport

Interplay among cellular polarization,lipoprotein metabolism and hepatitis C virus entry

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World Journal of Gastroenterology 2011年第22期17卷 2683-2690页

作者： Ignacio Benedicto Francisca Molina-Jiménez Ricardo Moreno-Otero Manuel López-cabrera pedro L Majano Molecular Biology Unit Hospital Universitario de la Princesa Instituto de Investigación Sanitaria Princesa (IP) Madrid 28006 Spain CIBERehd Instituto de Salud Car- los Ⅲ Madrid 28029 Spain Liver Unit Hospital Universitario de la Princesa Instituto de Investigación Sanitaria Princesa (IP) Madrid 28006 Spain Centro de Biología Molecular Severo Ochoa CSIC-UAM Madrid 28049 Spain

Hepatitis C virus (HCV) infects more than three million new individuals worldwide each year. In a high percent age of patients, acute infections become chronic, eventually progressing to fibrosis, cirrhosis, and hepatocellular carcinoma. Given the lack of effective prophylactic or therapeutic vaccines, and the limited sustained virological response rates to current therapies, new approaches are needed to prevent, control, and clear HCV *** into the host cell, being the first step of the viral cycle, is a potential target for the design of new antiviral compounds. Despite the recent discovery of the tight junction-associated proteins claudin-1 and occludin as HCV co-receptors, which is an important step towards the understanding of HCV entry, the precise mechanisms are still largely unknown. In addition, increasing evidence indicates that tools that are broadly employed to study HCV infection do not accurately reflect the real process in terms of viral particle composition and host cell phenotype. Thus, systems that more closely mimic natural infection are urgently required to elucidate the mechanisms of HCV entry, which will in turn help to design antiviral strategies against this part of the infection process.

关键词： Cellular polarization Tight junctions Lipoprotein metabolism Hepatitis C virus

Pretreatment inflammatory indices predict Bevacizumab response in recurrent Glioma

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Cancer Drug Resistance 2020年第3期3卷 623-635页

作者： Alicia Martínez-González Raquel cabrera Marta Lloret pedro C.Lara Department de Matemáticas Universidad de Castilla-La ManchaETSI IndustrialesAvdaCiudad Real 13071Spain. Oncología Radioterápica Hospital Universitario de Gran Canaria Dr Negrin Barranco de la Ballena s/nLas Palmas de Gran CanariaLas Palmas 35010Spain. Facultad de Ciencias de la Salud Universidad de Las Palmas de Gran CanariaPaseo de Blas Cabrera Felipes/nLas Palmas de Gran CanariaLas Palmas 35016Spain. Fundación Canaria del Instituto Canario de Investigación del Cáncer Avda de la Trinidad 61 Torre Agustín Arevalo 7 planta La LagunaSanta Cruz de Tenerife 38204Spain. San Roque University Hospitals Dolores de la Rocha5Las Palmas de Gran CanariaLas Palmas 35001Spain. Fernando Pessoa Canarias University Dolores dela Rocha 14Las Palmas de Gran CanariaLas Palmas 35016Spain.

Aim:It remains unclear what the best therapeutic option for recurrent glioma patients after Stupp treatment ***(BVZ)is commonly administered in progression,but it appears that only some patients *** would be useful to find biomarkers that determine beforehand who these patients ***:The protocol included 31 high-risk progressing glioma patients after Stupp treatment who received BVZ 5-10 mg/kg every 14 days and temozolomide(3-19 cycles,150-200 mg five days each 28-day cycle)during a mean of eight cycles of BVZ or until tumor progression or unacceptable *** analyzed the clinical outcome values of inflammatory indices measured before BVZ ***:Lymphocyte level before BVZ administration was the best independent predictor of overall survival(HR=0.34;95%CI:0.145-0.81;P=0.015).The area under the receiver operating characteristic(ROC)curve was 0.823,with 1.645 being the optimal cut-off value,and 0.80 and 0.85 the sensitivity and specificity values,*** and non-responder survival curves were also significantly different,considering the first and second tertiles as cut-off *** number of BVZ cycles was not related to *** neutrophil platelet levels,platelet-to-lymphocyte ratio(PLR),and neutrophil-to-lymphocyte ratio(NLR)did not have independent predictive *** variables were not correlated with each ***,patients with high NLR and PLR simultaneously(double positive PLR-NLR)showed a worse clinical outcome than the rest(P=0.043).Conclusion:Pretreatment lymphocyte levels and double positive PLR-NLR could be used as non-invasive hematological prognostic markers for recurrent gliomas treated with bevacizumab.A close relationship emerged between inflammation and angiogenesis.

关键词： Recurrent glioma bevacizumab predictive biomarker inflammatory indices lymphocytes

Recombinant streptokinase vs phenylephrine-based suppositories in acute hemorrhoids, randomized, controlled trial(THERESA-3)

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World Journal of Gastroenterology 2014年第6期20卷 1594-1601页

作者： Francisco Hernández-Bernal Georgina Castellanos-Sierra Carmen M Valenzuela-Silva Karem M Catasús-lvarez Roselin Valle-cabrera Ana Aguilera-Barreto pedro A López-Saura Center for Genetic Engineering and Biotechnology "Juan B. Zayas" Hospital National Center for the Coordination of Clinical Trials

AIM: To compare the efficacy and safety of recombinant streptokinase (rSK) and phenylephrine-based suppositories in acute hemorrhoidal disease.

关键词： Streptokinase Suppository Phenylephrine Thrombolysis Hemorrhoids Randomized clinical trial

Chronic hepatitis C in hemodialysis patients:Prevalence and liver fibrosis impact in the National Center for Renal Health in Peru

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iLIVER 2022年第3期1卷 141-144页

作者： P.Martin Padilla-Machaca Eduardo Luna-Victoria Ada cabrera Juan-Carlos Gómez-De la Torre Rocio Galloso pedro Montes Guillermo Almenara National Hospital EsSaludLimaPerú National University of San Marcos LimaPerú National Renal Health Center EsSaludLimaPerú Laboratorio Clínico Roe LimaPerú Asociacion Peruana para el Estudio del Hígado(APEH) LimaPerú

Background:Hepatitis C(HCV)remains a serious public health problem in high-risk persons such as patients on chronic *** aimed to estimate the serological prevalence of HCV,the HCV viral load and genotype,and liver fibrosis stage among patients on chronic hemodialysis at the National Renal Health Center in Lima,***:From June 2019 to March 2021,all patients who received chronic hemodialysis were invited to *** who provided written informed consent were *** with HCV-positive serology underwent determination of HCV viral *** from subjects with detectable viral load,underwent determination of HCV ***,HCV infected subjects underwent determination of liver fibrosis using transitional elastography(Fibroscan 402):Metavir score:F0-F1:2.5-7.5 kPa,F2:7.6-9.5 Kpa,F3:9.6-12 Kpa,F4(Cirrhosis):12.1-75 ***:Of the 303 subjects invited to participate,174(57.4%)subjects gave their written *** age was 52 years(range 22-91)and 116(66.6%)were *** serology was positive in 35.1%of patients(61/174);however,the prevalence of positive serology with detectable viral load was 20.11%(35/174).Genotype 1a was the most prevalent(85%).The majority(83.6%)of subjects with detectable viral load had values lower than 800.000 IU/***-nine of those 35 subjects underwent elastography evaluation,and 13(44.8%)of them were found to have stage F2-F4 ***:The prevalence of HCV at the largest reference center for hemodialysis in Lima remains high,with GT1a predominance,viral load usually below 800,000 IU/mL and significant liver fibrosis.

关键词： Hepatitis C Hemodialysis Liver fibrosis HCV genotype

Dominant Macroalgae in Bahía de Cochinos, Matanzas, Cuba

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American Journal of Plant Sciences 2022年第6期13卷 797-814页

作者： Yusimí Alfonso Patricia González Sánchez Hansel Caballero Aragón pedro Chevalier Jhoana Díaz-Larrea Ruben cabrera Acuario Nacional de Cuba La Habana Cuba Unidad Iztapalapa Departamento de Hidrobiología Universidad Autónoma Metropolitana Cd de México México Gabinete de Arqueología Oficina del Historiador de la Ciudad Habana Vieja Cuba

Spatial-temporal variations of macroalgae were analyzed in a study conducted in Cueva de Los Peces (CP) and Punta Perdiz (PP), two dive sites located on the eastern coast of Bahía de Cochinos. The most conspicuous species found from 3 to 20 m depths were present in the biotopes of ridges and shallow and deep terraces. Sampling was carried out in September 2014, and March and October 2016 by autonomous diving and direct methods. Qualitative visual censuses and quantitative analyzes were used to estimate the coverage (%) of the genera according to the AGRRA methodology with the use of the 10 m linear transect and quadrats as the sampling unit. The first list of macroalgae for the area is offered that includes 49 taxa of which 10 were Rhodophyta, 10 Ochrophyta (Phaeophyceae), and 29 Chlorophyta. The dominant genera during the study period were Halimeda, Dictyota, Lobophora, and Udotea. Spatial differences were found regarding the specific composition. Temporal variations were evidenced in terms of the relative abundance of the genera present, which reveals temporal changes in the qualitative structure, where some species replace others. The information obtained is pioneering and can serve as a comparative baseline for future monitoring of the area.

关键词： Cuba Macroalgae Spatial-Temporal Variations Species List

Microbial Community with Potential for Metal Release Isolated from Palca Mine Tailings Pond in Peru

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Journal of Geoscience and Environment Protection 2024年第7期12卷 109-121页

作者： César Wilber Guzmán Moreno Bruno Karolski Solange Kazue Utimura Roberto Castellanos cabrera Jhon Albert Centeno Torres Daladier Miguel Castillo Cotrina Elisabete de Santis Braga Dayana Sarai Gamonal Fermandez Denise Crocce Romano Espinosa Joel Barbujiani Sigolo Department of Sedimentary and Environmental Geology Institute of Geoscience USP So Paulo Brazil Department of Chemical Engineering LAREX USP So Paulo Brazil CEPEMA Environment Training and Research Center USP So Paulo Brazil Facultad de Ciencias Universidad Nacional Jorge Basadre Grohmann UNJBG Tacna Per Department of Physical Chemical and Geological Oceanography USP So Paulo Brazil Facultad de Ciencias Biolgicas Universidad Nacional Pedro Ruiz Gallo UNPRG Lambayeque Per

The improvement of microbial characterization has increased the comprehension of microbial population and their ability in the microbiological metal dissolution. Bioleaching processes have been expanded to use microorganisms for the recovery of metals from ores and wastes. This study introduces Palca mine tailings pond in Peru which turned into acid mine drainage (AMD). AMD is a source of microbial communities whose microorganisms may support the aqueous extractive metallurgy for metal recovery. Four samples of AMD were collected from different locations and the elemental characterization showed concentrations of metals, such as Cu, Zn, Al, Mn, and Fe. The pH of the samples showed variation between 1.9 - 6.8. Twenty-one microorganisms were isolated and selected according the cell morphology. 16s rRNA gene sequences identified five species of which three belong to the bacterial kingdom and two to the Fungi kingdom. Two of the bacterial species were ferrous ion oxidizing bacteria, identified as Acidithiobacillus ferriphilus and Acidithiobacillus ferridurans;and the other one a ferric ion reducing bacteria identified as Acidiphilium acidophilum. The fungi species identified were Rhodotorula sinensis and Exophiala xenobiotica, a filamentous fungus isolated for the first time from an AMD.

关键词： Acidophilic Microorganisms Acid Mine Drainage—AMD Bioleaching Process Metals Recovery Acidithiobacillus

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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Cellular & Molecular Immunology 2021年第9期18卷 2128-2139页

作者： Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-cabrera pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez E Clinical Unit of Infectious Diseases Microbiology and Preventive MedicineInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Medical Biochemistry Molecular Biologyand ImmunologySchool of MedicineUniversity of SevilleSevilleSpain Pneumology Service Galicia Sur Health Research Instituto(IIS Galicia Sur)SERGAS-UVigoVigoSpain Infectious Diseases Unit Department of Internal MedicineComplexo HospitalarioUniversitario de VigoIIS Galicia SurSERGAS-UVigoVigoSpain Group of Virology and Pathogenesis Galicia Sur Health Research Institute(IIS Galicia Sur)-Complexo Hospitalario Universitario de VigoSERGAS-UVigoVigoSpain Unit of Infectious Diseases Microbiologyand Preventive MedicineVirgen del Rocío University HospitalSevilleSpain Institute of Biomedicine of Seville(IBiS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain Medico-Surgical Unit of Respiratory Diseases Virgen del Rocío University HospitalSevilleSpain Unit of Emergencies Virgen del Rocío University HospitalSevilleSpain Intensive Care Unit Virgen del Rocío University HospitalSevilleSpain Department of Medicine University of SevilleSevilleSpain Cardiology and Cardiovascular Surgery Unit Virgen del Rocío University HospitalSevilleSpain Rheumatology Unit Virgen del Rocío University HospitalSevilleSpain Internal Medicine Unit Virgen del Rocío University HospitalSevilleSpain Digestive and Hepatobiliary Unit Virgen del Rocío University HospitalSevilleSpain Neurology and Clinical Neurophysiology Unit Virgen del Rocío University HospitalSevilleSpain Endocrinology and Nutrition Unit Virgen del Rocío University HospitalSevilleSpain Urology and Nephrology Unit Virgen del Rocío University HospitalSevilleSpain Unit of Clinical Investigation and Clinical Trials Virgen del Rocío University HospitalSevilleSpain

Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity *** cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease *** this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory ***,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 ***,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were *** findings contribute to a better understanding of the immunological sequelae of COVID-19.

关键词： SARS-CoV-2 COVID-19 Dendritic cell Long-COVID

Research and development of the back-end electronics for the two-dimensional improved resistive plate chambers in CMS upgrade

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Radiation Detection Technology and Methods 2021年第2期5卷 181-191页

作者： P.Cao Z-A.Liu J.Zhao H.Kou J.Tao J.Song W.Gong N.Wang A.Samalan M.Tytgat N.Zaganidis G.A.Alves F.Marujo F.Torres.Da.S.ilva.De.Araujo E.M.Da Costa D.De Jesus Damiao H.Nogima A.Santoro S.Fonseca De Souza A.Aleksandrov R.Hadjiiska P.Iaydjiev M.Rodozov M.Shopova G.Sultanov M.Bonchev A.Dimitrov L.Litov B.Pavlov P.Petkov A.Petrov S.J.Qian C.Bernal A.cabrera J.Fraga A.Sarkar S.Elsayed Y.Assran M.El Sawy M.A.Mahmoud Y.Mohammed X.Chen C.Combaret M.Gouzevitch G.Grenier I.Laktineh L.Mirabito K.Shchablo I.Bagaturia D.Lomidze I.Lomidze V.Bhatnagar R.Gupta P.Kumari J.Singh V.Amoozegar B.Boghrati M.Ebraimi R.Ghasemi M.Mohammadi Najafabadi E.Zareian M.Abbrescia R.Aly W.Elmetenawee N.De Filippis A.Gelmi G.Iaselli S.Leszki F.Loddo I.Margjeka G.Pugliese D.Ramos L.Benussi S.Bianco D.Piccolo S.Buontempo A.Di Crescenzo F.Fienga G.De Lellis L.Lista S.Meola P.Paolucci A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo B.Francois T.J.Kim J.Park S.Y.Choi B.Hong K.S.Lee J.Goh H.Lee J.Eysermans C.Uribe Estrada I.Pedraza H.Castilla-Valdez A.Sanchez-Hernandez C.A.Mondragon Herrera D.A.Perez Navarro G.A.Ayala Sanchez S.Carrillo E.Vazquez A.Radi A.Ahmad I.Asghar H.Hoorani S.Muhammad M.A.Shah I.Crotty Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium Centro Brasileiro Pesquisas Fisicas R.Dr.Xavier Sigaud150-UrcaRio de JaneiroRJ 22290-180Brazil Dep.de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524BR-Rio de Janeiro 20559-900RJBrazil Bulgarian Academy of Sciences Inst.for Nucl.Res.and Nucl.EnergyTzarigradsko shaussee Boulevard 721784 SofiaBulgaria Faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of Physics Peking UniversityBeijing 100871China Institute of High Energy Physics UCAS/CAS19(B)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Apartado Aereo 4976Carrera 1Eno.18A 10BogotaCOColombia Egyptian Network for High Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt The British University in Egypt(BUE) P.O.Box 43Elsherouk CitySuez Desert RoadCairo 11837Egypt Suez University Elsalam CitySuez-Cairo RoadSuez 43522Egypt Department of Physics Faculty of ScienceBeni-Suef UniversityBeni-SuefEgypt Center for High Energy Physics Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian Technical University 77 Kostava Str.Tbilisi 0175Georgia Department of Physics Panjab UniversityChandigarh 160014India School of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531TehranIran School of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso Univ.Monte S.AngeloVia Cintia80126 NaplesItaly INFN Sezione di PaviaVia Bassi 6PaviaItaly INFN Sezione di Pavia and University of PaviaVia Bassi 6PaviaItaly Hanyang University 222 Wangsimni-roSageun-dongSeongdong

Purpose To complement and ensure redundancy in the endcap muon system of the Compact Muon Solenoid(CMS)detector and to extend the Resistive Plate Chamber(RPC)system coverage,improved RPCs(iRPCs)with either orthogonal layer strips with one-end electronics or single layer strips with two-end electronics providing more precise time measurement will be installed in the very forward pseudorapidity region of|η|<*** iRPC readout system needs to support twodimensional(2D)or two-end *** addition,it must combine detector data with Timing,Trigger and fast Control(TTC)and Slow Control(SC)into one data stream over a bi-directional optical link with a line rate of 4.8 Gb/s between the Front-End Electronics(FEE)and the Back-End Electronics(BEE).To fulfill these requirements,a prototype BEE for the iRPC 2D chamber has been researched and *** A Micro-Telecommunication and Computing Architecture(μTCA)-based processing card was designed in this study to establish a prototype system together with aμTCA *** Giga-Bit Transceiver(GBT)protocol is integrated to provide bi-directional communication between the FEE and BEE.A server is connected with the BEE by a Gigabit Ethernet(GbE)link for SC and a 10-GbE link for Data AcQuisition(DAQ).Results The Bit Error Rate(BER)test of the back-end board and a joint test with the iRPC 2D prototype chamber were *** less than 1.331×10−16 was *** timemeasurement with a resolution of 3.05 nswas successfully realized,and detector efficiencies of 97.7%for longitudinal strips and 96.0%for orthogonal strips were *** results demonstrate the correctness and reliability of the prototype *** The BEE prototype satisfies the requirements for the iRPC 2D chamber,and it worked stably and reliably during a long-term joint test run.

关键词： CMS iRPC TTC SC BEE μTCA GBT DAQ

R&D of back-end electronics for improved resistive plate chambers for the phase 2 upgrade of the CMS end-capmuon system

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Radiation Detection Technology and Methods 2022年第3期6卷 306-316页

作者： H.Kou Z.-A.Liu J.Zhao J.Song Q.Hou W.Diao P.Cao W.Gong N.Wang A.Samalan M.Tytgat M.El Sawy G.A.Alves F.Marujo E.A.Coelho F.Torres Da Silva De Araujo E.M.Da Costa H.Nogima A.Santoro S.Fonseca De Souza D.De Jesus Damiao M.Thiel M.Barroso Ferreira Filho K.Mota Amarilo A.Aleksandrov R.Hadjiiska P.Iaydjiev M.Rodozov M.Shopova G.Sultanov A.Dimitrov L.Litov B.Pavlov P.Petkov A.Petrov E.Shumka S.J.Qian C.Avila D.Barbosa A.cabrera A.Florez J.Fraga J.Reyes Y.Assran M.A.Mahmoud Y.Mohammed I.Laktineh G.Grenier M.Gouzevitch L.Mirabito K.Shchablo C.Combaret W.Tromeur G.Galbit A.Luciol X.Chen I.Bagaturia I.Lomidze Z.Tsamalaidze V.Amoozegar B.Boghrati M.Ebraimi E.Zareian M.Mohammadi Najafabadi M.Abbrescia G.Iaselli G.Pugliese F.Loddo N.De Filippis R.Aly D.Ramos W.Elmetenawee S.Leszki I.Margjeka D.Paesani L.Benussi S.Bianco D.Piccolo S.Meola S.Buontempo F.Carnevali L.Lista P.Paolucci F.Fienga A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo E.Asilar J.Choi T.J.Kim S.Y.Choi B.Hong K.S.Lee H.Y.Oh J.Goh I.Yu C.Uribe Estrada I.Pedraza H.Castilla-Valdez R.L.Fernandez A.Sanchez-Hernandez E.Vazquez M.Ramirez-Garcia N.Zaganidis A.Radi H.Hoorani S.Muhammad A.Ahmad I.Asghar M.A.Shah W.A.Khan J.Eysermans I.Crotty on behalf of the CMS Muon Group Department of Physics and Astronomy Ghent UniversityProeftuinstraat 869000 GhentBelgium UniversitéLibre de Bruxelles Avenue Franklin Roosevelt50-1050 BruxellesBelgium Centro Brasileiro Pesquisas Fisicas R.Dr.Xavier Sigaud150UrcaRio de JaneiroRio de Janeiro 22290-180Brazil Department de Fisica Nuclear e Altas Energias Instituto de FisicaUniversidade do Estado do Rio de JaneiroRua Sao Francisco Xavier524Rio de JaneiroRio de Janeiro 20559-900Brazil Bulgarian Academy of Sciences Institute for Nuclear Researches and Nuclear EnergyTzarigradsko Shaussee Boulevard 721784 SofiaBulgaria Faculty of Physics University of Sofia5 James Bourchier Boulevard1164 SofiaBulgaria School of Physics Peking UniversityBeijing 100871China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences B325Main BuildingNo.19(A)Yuquan RoadShijingshan DistrictBeijing 100049China Universidad de Los Andes Carrera 1No.18A-12BogotáColombia Egyptian Network for High Energy Physics Academy of Scientific Research and Technology101 Kasr El-Einy St.CairoEgypt Suez University SuezCairo RoadElsalam CitySuez 43522Egypt Center for High Energy Physics(CHEP-FU) Faculty of ScienceFayoum UniversityEl-Fayoum 63514Egypt Univ Lyon Univ Claude Bernard Lyon 1CNRS/IN2P3IP2I LyonUMR 582269622 VilleurbanneFrance Georgian Technical University 77 Kostava Str.0175 TbilisiGeorgia School of Particles and Accelerators Institute for Research in Fundamental Sciences(IPM)P.O.Box 19395-5531 TehranIran School of Engineering Damghan UniversityDamghan ***Iran INFN Sezione di BariVia Orabona 470126 BariItaly INFN Laboratori Nazionali di Frascati(LNF)Via Enrico Fermi 4000044 FrascatiItaly INFN Sezione di NapoliComplesso University Monte S.AngeloVia Cintia80126 NapoliItaly Dipartimento di Ingegneria Elettrica e delle Tecnologie dell’Informazione UniversitàDegli Studi di Napoli Federico II80126 NapoliI

Purpose The Large Hadron Collider(LHC)at European Organization for Nuclear Research is planned to be upgraded to the high luminosity *** the luminosity makes muon triggering reliable and ofﬂine reconstruction very *** enhance the redundancy of the Compact Muon Solenoid(CMS)Muon system and resolve the ambiguity of track reconstruction in the forward region,an improved Resistive Plate Chamber(iRPC)with excellent time resolution will be installed in the Phase-2 CMS *** iRPC will be equipped with Front-End Electronics(FEE),which can perform high-precision time measurements of signals from both ends of the *** Back-End Electronics(BEE)need to be researched and developed to provide sophisticated functionalities such as interacting with FEE with shared links for fast,slow control(SC)and data,in addition to trigger primitives(TPs)generation and data acquisition(DAQ).Method The BEE prototype uses a homemade hardware board compatible with the MTCA standard,the back-end board(BEB).BEE interacts with FEE via a bidirectional 4.8 Gbps optical paired-link that integrates clock,data,and control *** clock and fast/slow control commands are distributed from BEB to the FEE via the *** uplink is used for BEB to receive the time information of the iRPC’sﬁred strips and the responses to the fast/slow control *** have a pipelined detector data for clusterﬁnding operation,recover(DeMux)the time relationship of which is changed due to the transmission protocol for the continuous incoming MUXed data from *** at each bunch crossing(BX),clusteringﬁred strips that satisfy time and spatial constraints to generate *** incoming raw MUXed detector data and TPs in a time window and latency based on the trigger signal are read out to the DAQ *** Ethernet(GbE)of SiTCP and commercial 10-GbE are used as link standards for SC and DAQ,respectively,for the BEB to interact with the *** The joint test results of

关键词： CMS iRPC BEE TP DAQ SC