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China's Refractories 2022年第2期31卷 1-6页

作者： Valeriy V.MARTYNENKo Vladimir V.PRIMACHENKo pavlo o.kushchenko Iri na G.SHULIK Ludmyla K.SAVINA The Ukrainian Research Institute of Refractories named after A.S.Berezhnoy Kharkiv 61024Ukraine

The use of a combined additive consisting of silica-containing additives“F”(thinning)and“S”(accelerating castable hardening)instead of the previously used silica-containing additive“A”and a mixture of dispersing additives based on polyethylene glycol in low-cement silicon carbide castable allows to improve the castable workability by increasing(in 5.4 times)the flowability of a freshly prepared castable,and increase by 1.2 and 1.1 times the cold crushing strength of heat-treated at temperatures of 110 and 1580°C,respectively,castable samples from low-cement silicon carbide castable with practically equal values of open porosity(15.8%and 16.0%).The petrographic studies of the castable sample microstructure after firing at a temperature of 1580°C showed that the investigated silica-containing additives“F”and“S”contribute to the denser and more uniform structure *** a result of the carried out research,the manufacturing technology of a low-cement silicon carbide castable was improved,of which the production was mastered at JSC“URIR named after ***”.

关键词： low-cement silicon carbide castable additives flowability structure strength

Blood biomarkers of Alzheimer’s disease:important considerations for use in clinical practice

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Neural Regeneration Research 2025年第1期20卷 205-206页

作者： Sarah Fullam Sean o’Dowd Antoinette o’Connor Department of Neurology Tallaght University HospitalDublinIreland Academic Unit of Neurology Trinity College DublinIreland

Introduction:Fluid and positron emission tomography(PET)biomarkers that enable the detection of the hallmark proteins of Alzheimer’s disease(AD)(amyloid and tau)have revolutionized our approach to the diagnosis of *** evolution of AD diagnostic criteria to include biological characterization(Alzheimer’s Association Working Group,2023)provides an appropriate framework to reduce levels of clinico-pathologic mismatch and improve in-vivo diagnostic *** the therapeutic landscape for neurodegenerative disease evolves,it is increasingly incumbent on clinicians to provide timely,and pathologically precise diagnoses for ***,the expensive and invasive nature of these tests limits their scalability.

关键词： Blood Alzheimer diagnosis

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João B.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell Biology(IBMC) University of PortoPortoPortugal Department of Biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Contribution of mechanical forces to structural synaptic plasticity:insights from 3D cellular motility mechanisms

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Neural Regeneration Research 2025年第7期20卷 1995-1996页

作者： Rita o.Teodoro Mafalda Ribeiro Ramos Lara Carvalho iNoVA4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no ***-intrinsic properties such as membrane lipid composition,abundance of mechanosensors,and cytoskeletal dynamics make cells more or less likely to sense these *** and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction(Yamada and Sixt,2019).Cell protrusions are extensions of the plasma membrane that play crucial roles in diverse contexts such as cell migration and neuronal synapse *** the nervous system,neurons are highly dynamic cells that can change the size and number of their pre-and postsynaptic elements(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called *** plasticity is a hallmark of the nervous system and is present throughout our lives,being required for functions like memory formation or the learning of new motor skills(Minegishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural mechanisms

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher J.o’Connell Matthew J.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA James L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

Effect of Ceo_2 and Al_2o_3 on the activity of Pd/Co_3o_4/cordierite catalyst in the three-way catalysis reactions(Co/No/C_nH_m)

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Journal of Environmental Sciences 2012年第7期24卷 1327-1333页

作者： Sergiy o.Soloviev pavlo I.Kyriienko Nataliia o.Popovych L.V.Pisarzhevsk Institute of Physical Chemistry National Academy of Sciences of Ukraine

The present article studies the effect of Ceo2 and A1203 on the activity of Pd/Co304/cordierite catalyst in conversion of No, Co, CnHm. The catalysts were characterized by temperature programmed reduction with hydrogen, X-ray diffraction, X-ray photoelectron spectroscopy and transmission electron microscopy. It is shown that the effect of Ceo2 on the properties of Pd/C03 o4/cordierite catalyst depends on preparation method. The catalyst obtained by co-deposition of cerium and cobalt oxides has higher activity in Co oxidation （Co ＋ 02 and Co ＋ No） and total hexane oxidation （C6H14 ＋ 02）. Such phenomenon is probably caused by more than stoichiometric amount of formed oxygen vacancies, an increase in both mobility of surface oxygen and dispersity of components in the catalytic composition. It is demonstrated that Ceo2 addition promotes the So2 resistance of Pd/C03 o4/cordierite. The second support decreases the activity of Pd/Co3oa/cordierite catalyst in the reactions of Co and C6H14 with oxygen because of CoA1204 formation.

关键词： metal-oxide catalysts structured catalysts effect of Ceo2 and A1203 Co No CnH,. conversion

Coarse to Fine: The Role of Severe Plastic Deformation in Advancing Titanium-Based Medical Implants - A Comprehensive Review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 295-306页

作者： Dragana R Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko R Djokić Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear Sci-ences-National Institute of the Republic of Serbia University of Belgrade11001BeogradSerbia Innovation Centre of the Faculty of Technology and Metallurgy Karnegijeva 411120 BelgradeSerbia

This paper describes severe plastic deformation(SPD)procedures,which are utilized to form an ultrafine-grained structure in metallic *** the SPD process,a solid material sample is subjected to very high loads without a significant change in sample *** the present work,the high-pressure torsion(HPT)process,as one of the SPD techniques,which achieves a high degree of deformation and ensures refinement of the microstructure,will be discussed in more *** that grain size control is accepted as a method to obtain materials with desired characteristics,an overview of the properties of ultrafine-grained titanium-based biomaterials to be used in medicine is ***,particular attention is dedicated to the influences of HPT process parameters,primarily hydrostatic pressure,and number of revolutions during torsion,on the grain size and physical and mechanical characteristics(modulus of elasticity,microhardness,and tensile properties),corrosion resistance,and biocompatibility of the titanium-based biomaterials.A review of the literature indicates that titanium-based materials obtained by the SPD process show improved mechanical and physical properties without losing biocompatibility and corrosion resistance,which suggests that these methods of obtaining implants are something that should be further developed in the future.

关键词： high-pressure torsion process ultrafine-grained titanium-based materials electrochemical anodization physical properties mechanical properties

Selective catalytic reduction of NoX with ethanol and other C1-4 oxygenates over Ag/Al2o3 catalysts: A review

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Frontiers of Chemical Science and Engineering 2020年第4期14卷 471-491页

作者： pavlo I.Kyriienko L.V.Pisarzhevskii Institute of Physical Chemistry of the NAS of Ukraine Kyiv 03028Ukraine

Research results regarding selective catalytic reduction(SCR)of Nox with ethanol and other C1-4 oxygenates as reductants over silver-alumina catalysts are *** aspects of the process mechanism,nature of active sites,role of alumina and silver(especially in the formation of bifunctional active sites),effects of reductants and reaction conditions are *** has been determined that key stages of the process include formation of reactive enolic species,their interaction with Nox and formation of nitroorganic compounds which transform to NCoads species and further to *** results obtained over various silver-alumina catalysts demonstrate the perspectives of their application for reducing the level of nitrogen oxides in engine emissions,including in the presence of water vapor and sulfur *** to improve the catalysts for the SCR of Nox with C1-4 oxygenates are outined.

关键词： SCR nitrogen oxides silver-alumina catalyst silver species ethanol oxygenates

Dynamic stress concentration in an infinitely long cylindrical cavity due to a point spherical source embedded within a fluid-saturated poroelastic formation of infinite extent

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 139-156页

作者： H.HoSSEINI o.BALILASHAKI Department of Mechanical Engineering Faculty of EngineeringGolestan University

The effects of a harmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely within a fluid-saturated poroelastic formation of infinite extent are examined theoretically. It is assumed that the source is located outside the cavity at a specified distance from the borehole axis. The magnitudes of the hoop and radial stresses beside the pore pressures exerted on the interface and inside the porous medium surrounding the borehole are calculated and discussed. Biot's poroelastic modeling along with three types of boundary conditions for the cylindrical interface including the ideal fluid, empty borehole, and rigid inclusion with a hard boundary is employed for the analysis. Utilizing a proper translational addition theorem for expressing the incident spherical wave in terms of cylindrical wave expansions, the proposed boundary conditions at the interface are satisfied. Stresses are formulated by means of wave potential functions in a three-dimensional(3D) manner. The effects of the frequency and the radial distance between the source and borehole on the induced stresses are examined for the first cylindrical modes over frequency spectra. Two permeability conditions for the interface and three types of soils for the porous formation are considered throughout the analysis. To give an overall outline of the study, a numerical example is presented. The results clearly indicate that the distance is a key parameter and has considerable effects on the induced stress values. In addition, the interface permeability condition and soil characteristics play an important role in determining the dynamic response of the borehole. Finally,the obtained results are compared with the relevant analyses existing in the literature for some limit cases, and good agreement is achieved.

关键词： point source cylindrical cavity porous medium wave-field transformation stress concentration o353.4

Metal alginates for polyphenol delivery systems: Studies on crosslinking ions and easy-to-use patches for release of protective flavonoids in skin

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Bioactive Materials 2020年第3期5卷 447-457页

作者： João Silva pavlo Vanat Dorinda Marques-da-Silva Joaquim Rui Rodrigues Ricardo Lagoa School of Technology and Management Polytechnic Institute of LeiriaPortugal Laboratório Associado LSRE-LCM School of Technology and ManagementPolytechnic Institute of LeiriaPortugal UCIBIo-Faculty of Science and Technology NOVA University of LisbonPortugal

Incorporation of bioactive natural compounds like polyphenols is an attractive approach for enhanced functionalities of *** particular flavonoids have important pharmacological activities,and controlled release systems may be instrumental to realize the full potential of these *** presents interesting attributes for dermal and other biomaterial applications,and studies were carried here to support the development of polyphenol-loaded alginate *** of capillary viscosity indicated that ionic medium is an effective strategy to modulate the polyelectrolyte effect and viscosity properties of *** gelation,considerable differences were observed between alginate gels produced with Ca^2+,Ba^2+,Cu^2+,Fe^2+,Fe^3+and Zn^2+as crosslinkers,especially concerning shrinkage and morphological *** assays with different polyphenols in the presence of alginate-gelling cations pointed to the choice of calcium,barium and zinc as safer ***-based films loaded with epicatechin were prepared and the kinetics of release of the flavonoid *** results with calcium,barium and zinc alginate matrices indicated that the release dynamics is dependent on film thicknesses,but also on the crosslinking metal *** these grounds,an alginate-based system of convenient use was devised,so that flavonoids can be easily loaded at simple point-of-care conditions before dermal *** epicatechin-loaded patch was tested on an ex-vivo skin model and demonstrated capacity to deliver therapeutically relevant concentrations on skin ***,the flavonoid released was not modified and retained full antioxidant *** alginate-based system proposed offers a multifunctional approach for flavonoid controllable delivery and protection of skin injured or under risk.

关键词： Topical drug delivery Intrinsic viscosity Biopolymer Epigallocatechin-gallate Antioxidant dressing