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Pyoderma gangrenosum affecting the mouth

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Open Journal of Stomatology 2013年第2期3卷 142-145页

作者： Marcos Martins Curi Camila Lopes Cardoso Daniel Henrique Koga Cristina Zardetto sergio Rocha Araujo Department of Stomatology Hospital Santa CatarinaSao PauloBrazil Department of Stomatology Bauru School of DentistryUniversity of Sao PauloBauruSao PauloBrazil

Pyoderma gangrenosum is a rare ulcerative cutaneous disorder commonly associated with systemic diseases such as inflammatory bowel diseases. This paper reports a case of pyoderma gangrenosum affecting the mouth and the skin associated with ulcerative colitis. A Medline search in English literature from 1961 to 2012 revealed only 11 documented cases of pyoderma gangrenosum with oral involvement. Previous reported cases of oral cavity involvement have shown that the most common sites of manifestation are the tongue, palate, and tonsillar fauces. This case emphasizes the importance of including inflammatory bowel diseases and their manifestations in the differential diagnosis of ulcerative lesions in the oral cavity.

关键词： Pyoderma Gangrenosum Oral Manifestation Inflammatory Bowel Disease Ulcerative Colitis

Short-term outcomes after laparoscopic colorectal surgery in patients with previous abdominal surgery: A systematic review

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World Journal of Gastrointestinal Surgery 2016年第7期8卷 533-540页

作者： Marleny Novaes Figueiredo Fabio Guilherme Campos Luiz Augusto D'Albuquerque sergio Carlos Nahas Ivan Cecconello Yves Panis Department of Gastroenterology University of S?o Paulo Medical School Division of Colorectal Surgery Department of Gastroenterology Hospital das Clínicas University of S?o Paulo Medical School Department of Gastroenterology Hospital das Clínicas University of S?o Paulo Medical School Department of Colorectal Surgery P?le des Maladies de l’Appareil Digestif (PMAD)

AIM: To perform a systematic review focusing on shortterm outcomes after colorectal surgery in patients with previous abdominal open surgery(PAOS).METHODS: A broad literature search was performed with the terms "colorectal", "colectomy", "PAOS", "previous surgery" and "PAOS". Studies were included if their topic was laparoscopic colorectal surgery in patients with PAOS, whether descriptive or comparative. Endpoints of interest were conversion rates, inadvertent enterotomy and morbidity. Analysis of articles was made according to Preferred Reporting Items for Systematic Reviews and ***: From a total of 394 citations, 13 full-texts achieved selection criteria to be included in the study. Twelve of them compared patients with and without PAOS. All studies were retrospective and comparative and two were case-matched. The selected studies comprised a total of 5005 patients, 1865 with PAOS. Among the later, only 294(16%) had history of a midline incision for previous gastrointestinal surgery. Conversion rates were significantly higher in 3 of 12 studies and inadvertent enterotomy during laparoscopywas more prevalent in 3 of 5 studies that disclosed this event. Morbidity was similar in the majority of studies. A quantitative analysis(meta-analysis) could not be performed due to heterogeneity of the studies. CONCLUSION: Conversion rates were slightly higher in PAOS groups, although not statistical significant in most studies. History of PAOS did not implicate in higher morbidity rates.

关键词： Previous abdominal surgery Laparoscopic surgery Colorectal surgery Previous abdominal surgery Laparoscopy

Update on the use of portable monitoring system for the diagnosis of sleep apnea in specific population

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World Journal of Respirology 2015年第1期5卷 17-27页

作者： Erika Treptow Marcia Goncalves Oliveira Gustavo Antonio Moreira Sonia Togeiro Luiz Eduardo Nery sergio Tufik Lia Bittencourt Departamento Psicobiologia Departamento de PsicobiologiaUniversidade Federal de Sao Paulo (UNIFESP) Disciplina de Pneumologia Departamento de MedicinaUniversidade Federal de Sao Paulo (UNIFESP)

The prevalence and severity of obstructive sleep apnea(OSA) is higher in specific population: children, elderly,obese and patients with pulmonary and cardiovascular diseases, compared to the general population. OSA is associated with greater morbidity and mortality in these patients. Although full-night polysomnography is still the gold standard diagnostic sleep study for OSA, it is a time consuming, expensive and technically demanding exam. Over the last few years, there is growing evidence on the use of portable monitors(PM) as an alternative for the diagnosis of OSA. These devices were developed specially for sleep evaluation at home, at a familiar environment, with easy selfapplication of monitoring, unattended. The use of PM is stablished for populations with high pre-test probability of OSA. However, there is a lack of studies on the use of PM in age extremes and patients with comorbidities. The purpose of this review is to present the studies that evaluated the use of PM in specific population, as well as to describe the advantages, limitations and applications of these devices in this particular group of patients. Although the total loss rate of recordings is variable in different studies, the agreement with fullnight polysomnography justifies the use of PM in this population.

关键词： Out-of-center sleep testing Obesity Home unattended portable monitoring Elderly Children Portable monitoring Cardiovascular diseases Chronic obstructive pulmonary disease Polysomnography

Euborellia annulipes Mortality and Predation on Diatraea saccharalis Eggs after Application of Chemical and Biological Insecticides

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Agricultural Sciences 2023年第1期14卷 11-22页

作者： Rodrigo Marin Arroyo Joice Mendonça De Souza Gilmar Da Silva Nunes Dagmara Gomes Ramalho sergio Antonio De Bortoli UNESP S&#227 o paulo State University Jaboticabal SP Brazil Manserv Porto Nacional Tocantins Brazil

Chemical and biological insecticides have been frequently used in sugarcane fields to control insects-pests, including the sugarcane borer, Diatraea saccharalis. Among the products used, those based on chlorantraniliprole and Metarhizium anisopliae entomopathogenic fungus, stand out. Euborellia annulipes is an insect of the order Dermaptera considered a potential predator of sugarcane borer eggs. This study aimed to evaluate the direct and indirect effects of the bioinsecticide based on M. anisopliae (Metarril®) and the chemical insecticide chlorantraniliprole (Altacor®) on the mortality of E. annulipes nymphs and adults, the predation and feeding preference of earwigs in eggs treated with the formulated products. Predator mortality was evaluated for seven days after treatment, while the effect on predation was analyzed by preference tests with and without choice, using prey eggs. The products tested were selective to the predator, causing ≤ 2% mortality and not affecting predation. The application of M. anisopliae on sugarcane borer eggs favored the food preference of fourth-instar nymphs, males, and females of the predator. Our results show that Metarril® and Altacor® can be used to control D. saccharalis when associated with the predator E. annulipes.

关键词： Sugarcane Borer Biological Control Food Preference Earwigs

Oral Manifestations, Gingival Index and Dental State of Vesiculobullous Diseases

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International Journal of Clinical Medicine 2018年第5期9卷 408-422页

作者： sergio Eduardo Migliorini Vanessa Gallego Arias Pecorari Marcio Zaffalon Casati Claudia Giuli Santi Cyro Festa Neto Luciano Lauria Dib Paulista University (UNIP) S&atilde o paulo Brazil Department of Bioestatistic Paulist University (UNIP) S&atilde o paulo Brazil Department of Peridontal Campinas State University S&atilde o paulo Brazil Department of Dermatology University of S&atilde o paulo S&atilde o paulo Brazil Department of Stomatology Paulist University (UNIP) S&atilde o paulo Brazil

Objective: To determine the occurrence of oral manifestations, gingival index, dental state and associated therapeutic aspects in patients with vesiculobullous diseases. Study design: Prospective and observational study conducted with 69 patients from May 2013 to May 2014 at the Dermatology Outpatient Clinic of the Clinical Hospital, University of São paulo Medical School, Brazil. Data were analyzed for frequency in absolute values, percentage and correlation using the Chi-square test. Results: 84.1% of the patients had oral manifestations of vesiculobullous diseases (p = 0.001);25% had gingival lesions;18.2% had lesions in the buccal mucosa, and 17.6% in the lips, with no correlation between the location and the type of disease (p = 0.990). Among all patients with bullous pemphigoid, linear IgA dermatosis, and mucous membrane pemphigoid, 59 (93.6%) patients had gingival inflammation of dental origin but without significant correlation (p = 0.42). There was correlation between pemphigus vulgaris and periodontal disease (p = 0.05). Conclusion: Gingival inflammation seems to interfere negatively with the clinical course of these diseases. Further studies should be conducted to better clarify the interrelations between dental and gingival state, and between vesiculobullous diseases and oral involvement.

关键词： Oral Medicine Autoimmune Diseases Pemphigus Periodontal Diseases Bullous Pemphigoid

Microbial enzymatic stoichiometry and the acquisition of C, N,and P in soils under different land-use types in Braziliansemiarid

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Soil Ecology Letters 2023年第3期5卷 101-108页

作者： Erika Valente de Medeiros Érica de Oliveira Silva Gustavo Pereira Duda Mario Andrade Lira Junior Uemeson Josédos Santos Claude Hammecker Diogo Paes da Costa Fabio Fernando Araujo Arthur Prudêncio de Araujo Pereira Lucas William Mendes Ademir sergio Ferreira Araujo Laboratory of Microbiology and Enzymology-LEMA Federal University of Agreste PernambucoGaranhuns 55292-270Brazil Federal Rural University of Pernambuco Rua Dom Manuel de Medeiross/nDois Irmãos52171-900RecifeBrazil Soil-Agrosystem-Hydrosystem Interaction Lab-LISAH Place Pierre Viala234060 MontpellierFrance Universidade do Oeste Paulista Presidente PrudenteSPBrazil Departamento de Ciência Do Solo Universidade Federal Do CearáFortalezaCEBrazil Center for Nuclear Energy in Agriculture University of Sao PauloPiracicabaSPBrazil Soil Quality Lab Agricultural Science CenterFederal University of PiauíTeresinaPI 60049-550Brazil

This study hypothesized that different land-use affect the microbial enzymatic stoichiometry and C-,N-,and P-acquisition in Brazilian semiarid ***,the enzymesβ-glucosidase(C-acquiring enzyme),urease(N-acquiring enzyme),and acid phosphatase(P-acquiring enzyme)were assessed in soil samples collected at 0−5 and 5−10 cm depth from a tropical dry forest,a protected area with Angico,a protected area with Ipê,scrub area,and an agricultural area with *** values of C-,N-,and P-acquiring enzymes were used to calculate the enzymatic C:N,C:P,and N:P *** values of C:P and N:P ratios were higher at 0−5 cm depth,while no significant variation,between soil depth,was observed for C:N *** values of C-and N-acquiring enzymes were higher at 0−5 cm in tropical dry forest areas and Angico forest,*** all land use types,the values of vectors L and A were higher than 1°and 45°,*** study showed that both land-use and soil depth influence the enzymatic stoichiometry,showing higher values of C-and N-acquiring enzymes in native and protected forests at soil surface.

关键词： C:N:P stoichiometry tropical forests soil depth Luvisols

Pancreatitis after endoscopic retrograde cholangiopancreatography:A narrative review

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World Journal of Gastroenterology 2021年第20期27卷 2495-2506页

作者： Igor Braga Ribeiro Epifanio Silvino do Monte Junior Antonio Afonso Miranda Neto Igor Mendonça Proença Diogo Turiani Hourneaux de Moura Mauricio Kazuyoshi Minata Edson Ide Marcos Eduardo Lera dos Santos Gustavo de Oliveira Luz sergio Eiji Matuguma Spencer Cheng Renato Baracat Eduardo Guimarães Hourneaux de Moura Department of Gastrointestinal Endoscopy Unit University of São Paulo School of MedicineSão Paulo 05403-010Brazil

Acute post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP)is a feared and potentially fatal complication that can be as high as up to 30%in high-risk ***-examination measures,during the examination and after the examination are the key to technical and clinical success with a decrease in adverse *** studies have debated on the subject,however,numerous topics remain controversial,such as the effectiveness of prophylactic medications and the amylase dosage *** review was designed to provide an update on the current scientific evidence regarding PEP available in the literature.

关键词： Endoscopic retrograde cholangiopancreatography Pan-creatitis Postendoscopic retrograde cholangiopancreatography pancreatitis Adverse events Pancreatitis Prevention

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拉丁与创意

中国广告 2015年第9期 41-42页

作者：林朗 sergio Alcocer Andrezza Valentin Alex Pallete 美国LatinWork广告公司巴西BOSSA NYC/S?o paulo 西班牙马德里PICNIC

喜力啤酒在今年的创意节上收获颇丰。在说到喜力为何会成为戛纳的宠儿时,Hagh回答道,啤酒制造者坚信创意就是产业的基石,而这一观念早已渗透入公司的各个阶层。“我们始终坚信我们在酿造最纯正的啤酒,我们从未妥协,我们也从不抄近路。... 详细信息

喜力啤酒在今年的创意节上收获颇丰。在说到喜力为何会成为戛纳的宠儿时,Hagh回答道,啤酒制造者坚信创意就是产业的基石,而这一观念早已渗透入公司的各个阶层。“我们始终坚信我们在酿造最纯正的啤酒,我们从未妥协,我们也从不抄近路。所以我们的价格绝对不会是最便宜的。但是如果你热衷于伟大的产品,那么你就需要找到伟大的说故事的方法,以此来证明这一伟大的产品是非常值得购买的。＂

关键词：戛纳啤酒制造广告作品喜力啤酒广告内容广告活动常胜将军通用语言品牌精神核心品牌

Evaluation of immunogenicity elicited from two DNA vaccine candidates that expresses the prM and E genes of the dengue-3 virus

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Health 2010年第11期2卷 1298-1307页

作者： sergio Ode Paula Rafael FOFranca Danielle MLima Nina RDutra Marilia Bde Paula Michelle Dde Oliveira Leandro Lde Oliveira Benedito ALda Fonseca Department of General Biology Federal University of VicosaVicosa-MGBrazil Department of Internal Medicine School of Medicine of Ribeirao Preto-USPRibeirao PretoBrazil

In this work, we report the evaluation of two DNA vaccines against dengue-3 virus (DENV-3). The first construction, called pVAC3DEN3, was engineered inserting the pre-membrane (prM) and envelope (E) gene of DENV-3 truncated with a restriction site between them, as previously described. The second construction was developed cloning the full gene sequence of prM and E from DENV-3 virus in pCI plasmid for mammalian expression and was denominated pVAC1WDEN3. The results showed that both constructions were capable of expressing the prM and E proteins, as demonstrated by ELISA and immunoblotting detection in cell culture transfected with the plasmids. After positive “in vitro” results, the vaccine candidates were used to immunize BALB/c mice and the elicited response was investigated. After immunization by intramuscular inoculation with three doses of each vaccinal clone the animals were sacrificed, the cytokine levels and T cell response were analyzed in the spleens, after three days of culture with stimulus, our analysis showed that the two constructions elicited T cell responses mea- sured by BrdU incorporation assay and high levels of IFN-γ, detected in the supernatant of the cultures. Moreover, both constructions induced detectable titers of neutralizing antibodies in mice. And finally the survival rate of the immunized animals after intracerebral challenge was analyzed, showing a better result in the pVAC3DEN3 group with an 80% survival compared with a 50% survival of the pVAC1 WDEN3. Thus, these data showed that our two constructions were able to induce specific immune response and protects mice against a lethal challenge with DENV-3, and these vaccine candidates can be employed to develop a viable dengue vaccine.

关键词： Dengue DNA Vaccine E Protein