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Comparative Study on Cerebral Processing among Elderly People with Either Intellectual or Mechanical Work Activities, by Means of Electroencephalographic Techniques

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Journal of Behavioral and Brain Science 2020年第8期10卷 311-322页

作者： Arisson Euclides da Silva Leonardo Coelho de Mendonça Silva Lousane Leonoura Alves Santos Diêgo Lucas Ramos e Silva paulo josé medeiros de souza costa Milton Vieira costa josé Claudio da Silva Euclides Mauricio Trindade Filho State University of Health Sciences of Alagoas Biological Science Nucleus Maceió Brasil State University of Health Sciences of Alagoas Nucleus of Maternal Child and Adolescent Health Maceió Brasil

Background: The cognitive capacity is one of the determinants of quality of life in old age. In EEG, gamma rhythm represented electrical correlates of execution of cognitive activities. Objective: To compare the cortical areas activated during executive activities through the gamma rhythm (25 - 45 Hz) and the performance in the Frontal Assessment Battery (FAB) among older people who exercised intellectual and mechanical work during their lifetime. Methods: We compared the electroencephalographic record of the gamma rhythm potential (25 - 45 Hz) in the cortical quadrants during the execution of the FAB among 13 elderly people who exercised intellectual activity and 12 elderly people who performed mechanical work. Results: In the FAB, the intellectual group obtained a better performance with a mean score of 16.2/18, while the mechanical group obtained an average score of 14.9/18. Only a significant difference between groups was observed in the similarity test, with intellectual group leadership. There was no significant difference between groups in the overall analysis of gamma rhythm potential in the brain quadrants during the tests. Conclusion: Elderly people who performed intellectual activity performed better than the elderly who exercised mechanical work in the execution of the Frontal Evaluation Battery (FAB). There was a greater quantification of gamma rhythm in the group of elderly individuals who exercised intellectual activity, compared to those who exercised mechanical activity.

关键词： Electroencephalography Aged Gamma Rhythm

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The effect of abiotic stresses on plant C:N:P homeostasis and their mitigation by silicon

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The Crop Journal 2024年第2期12卷 340-353页

作者： Milton Garcia costa Renato de Mello Prado Luiz Fabiano Palaretti Jonas Pereira de souza Júnior department of Agricultural Production Science School of Agricultural and Veterinarian SciencesSão Paulo State UniversityJaboticabalBrazil

In crop plants, various environmental stresses affect the balance of carbon, nitrogen, and phosphorus(C:N:P), leading to biochemical and physiological alterations and reductions in yield. Silicon(Si) is a beneficial element that alleviates plant stress. Most studies involving silicon have focused on physiological responses, such as improvements in photosynthetic processes, water use efficiency, and antioxidant defense systems. But recent research suggests that stressed plants facing either limited or excessive resources(water, light, nutrients, and toxic elements), strategically employ Si to maintain C:N:P homeostasis, thereby minimizing biomass losses. Understanding the role of Si in mitigating the impact of abiotic stresses on plants by regulating C:N:P homeostasis holds great potential for advancing sustainable agricultural practices in crop production. This review presents recent advances in characterizing the influence of environmental stresses on C:N:P homeostasis, as well as the role of Si in preserving C:N:P equilibrium and attenuating biological damage associated with abiotic stress. It underscores the beneficial effects of Si in sustaining C:N:P homeostasis and increasing yield via improved nutritional efficiency and stress mitigation.

关键词： Nutritional stoichiometry Elemental stoichiometry Beneficial element Environmental stresses Nutritional efficiency Carbon use efficiency Agricultural sustainability

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Starch Orodispersible Film Loaded with Melatonin for Human Supplementation

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Journal of Renewable Materials 2024年第7期12卷 1343-1354页

作者： Fabio Tamanini Tatiane Zucchini de souza Creusa Sayuri Tahara Amaral Antônio joséFelix Carvalho Eliane Trovatti department of Health and Biological Sciences University of Araraquara(UNIARA)São Paulo14801-340Brazil department of Materials Engineering São Carlos School of EngineeringUniversity of São PauloSão Paulo13563-120Brazil

An innovative pharmaceutical form for administering melatonin,based on starch orodispersibleﬁlm(ODF),was designed and *** composition of the ODF included starch as the polymer matrix,the active drug melatonin,and a ***,a natural hormone produced by the pineal gland in the brain,can be absorbed by passive diffusion across the mucous membrane,resulting in improved bioavailability when compared to conventional oral *** study shows a simple and efﬁcient method for preparing melatonin-loaded orodispersibleﬁlms with a physically stable and commercially viable matrix,suitable for use in the pharmaceutical ***ﬁlms were prepared by treating the starch with microwave irradiation,followed by plasticization with glycerol,melatonin loading and drying by solvent *** tests showed theﬁlms’robustness,with a modulus of approximately 97 MPa,indicating good handling *** uptake analysis showed fast water absorption,reaching about 150%within 2 min,indicating its fast oral disintegration *** tests in artiﬁcial saliva and dissolution studies indicated the release of the drug in min-utes,indicating the potential properties of theﬁlm for oral drug *** the best of our knowledge,there is no melatonin ODF based on starch described in the literature.

关键词： Starch orodispersibleﬁlm melatonin drug delivery

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Benchmarks for Pirá2.0,a Reading Comprehension Dataset about the Ocean,the Brazilian Coast,and Climate Change

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Data Intelligence 2024年第1期6卷 29-63页

作者： paulo Pirozelli Marcos M.josé Igor Silveira Flávio Nakasato Sarajane M.Peres Anarosa A.F.Brandão Anna H.R.costa Fabio G.Cozman Universidade de São paulo Ringgold Standard Institution-Instituto de Estudos Avançados Av.370 São Paulo 05508-900Brazil Universidade de São paulo Ringgold Standard Institution-Instituto de Matemática e Estatística Av.370 São Paulo 05508-900Brazil Universidade de São paulo Rua Cayowaá876 apto 141SÃO PAULO 05018-001Brazil Universidade de São paulo Ringgold Standard Institution Escola Politécnica Av.370São Paulo 05508-900Brazil.

Piráis a reading comprehension dataset focused on the ocean,the Brazilian coast,and climate change,built from a collection of scientific abstracts and reports on these *** dataset represents a versatile language resource,particularly useful for testing the ability of current machine learning models to acquire expert scientific *** its potential,a detailed set of baselines has not yet been developed for Pirá.By creating these baselines,researchers can more easily utilize Piráas a resource for testing machine learning models across a wide range of question answering *** this paper,we define six benchmarks over the Pirádataset,covering closed generative question answering,machine reading comprehension,information retrieval,open question answering,answer triggering,and multiple choice question *** part of this effort,we have also produced a curated version of the original dataset,where we fixed a number of grammar issues,repetitions,and other ***,the dataset has been extended in several new directions,so as to face the aforementioned benchmarks:translation of supporting texts from English into Portuguese,classification labels for answerability,automatic paraphrases of questions and answers,and multiple choice *** results described in this paper provide several points of reference for researchers interested in exploring the challenges provided by the Pirádataset.

关键词： Natural language processing Question answering Benchmarks Language resource DomainOriented dataset Scientific knowledge text dataset

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Changes in calcium accumulation and utilization efficiency and their impact on recycling,immobilization,and export across the oil palm cycle

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Oil Crop Science 2024年第3期9卷 143-150页

作者： Ismael de Jesus Matos Viégas Luma Castro de souza Eric Victor de Oliveira Ferreira Milton Garcia costa Glauco André dos Santos Nogueira Vitor Resende do Nascimento Candido Ferreira de Oliveira Neto Capanema Campus Federal Rural University of the Amazon(UFRA)Av.Barao de CapanemaCaixa D'agua5514-6434ParaBrazil Center of Agricultural and Environmental Sciences Federal University of Maranhao(UFMA)ChapadinhaBR-222km 04SNBoa Vista65500000MaranhaoBrazilc Capitao Poço Campus Federal Rural University of the Amazon(UFRA)Tv.Pau AmareloS/n-Vila Nova68650-000Capitao PoçoParaBrazil department of Soil Science Sao Paulo State University(Unesp)School of Agricultural and Veterinarian SciencesJaboticabalVia de Acesso Prof.Paulo Donato CastelaneCastellane-S/N-Vila Industrial14884-900Sao PauloBrazil Institute of Agricultural Sciences(ICA) Federal Rural University of the Amazon(UFRA)Estr.Principal da Ufra2150Curio-Utinga66077-580BelemParaBrazil

Effective calcium(Ca)management is crucial for optimizing oil palm cultivation and enhancing crop *** study aimed to gain insights into the dynamics of Ca concentration,accumulation,exportation,immobilization,and recycling in various oil palm organs relative to plant *** experiment was conducted at the Agropalma enterprise site in the northeastern region of Para State,Brazil,evaluating seven plant age treatments:2,3,4,5,6,7,and 8 years *** a completely randomized design with four *** results demonstrated an age-related increase in Ca concentration in petioles,rachis,arrows,male inflorescences,peduncles,and ***,Ca accumulation exhibited an upward trend in all organs with progressing plant ***,the study revealed an enhanced Ca use efficiency across all plant organs in correlation with the age of oil palm *** findings underscore the dynamic nutritional demands of oil palm,influencing Ca immobilization,cycling,and export throughout its developmental stages.

关键词： Elaeis guineensis Jacq Ca cycling Ca export Ca immobilization Ca use efficiency Plant nutrition Amazon

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Resilience-Oriented Approach to the Control of Ventricular Assist devices

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Journal of Biomedical Science and Engineering 2024年第8期17卷 137-156页

作者： Jônatas Cerqueira Dias Jeferson Cerqueira Dias Milena Victoria de Azevedo souza Diolino josé dos Santos Filho department of Mechatronic Engineering and Mechanical Systems Universidade de So Paulo (USP) So Paulo Brazil department of Mechatronic Engineering and Mechanical Systems Universidade de So Paulo (USP) So Paulo Brazil department of Biomedical Technology Faculdade de Tecnologia Prefeito Hirant Sanazar (FATEC OSASCO) Osasco Brazil

Context: Advanced heart failure (AHF) poses a global challenge, where heart transplantation is a treatment option but limited by donor scarcity. Proposal: This study aims to enhance the performance of ventricular assist devices (VADs) in the face of adverse events (AEs) using a resilience-based approach. The objective is to develop a method for integrating resilience attributes into VAD control systems, employing dynamic risk analysis and control strategies. Results: The outcomes include a resilient control architecture enabling anticipatory, regenerative, and degenerative actions in response to AEs. A method of applied resilience (MAR) based on dynamic risk management and resilience attribute analysis was proposed. Conclusion: Dynamic integration between medical and technical teams allows continuous adaptation of control systems to meet patient needs over time, improving reliability, safety, and effectiveness of VADs, with potential positive impact on the health of heart failure patients.

关键词： Heart Failure Ventricular Assist devices Resilience Dynamic Control

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Rifaximin on epigenetics and autophagy in animal model of hepatocellular carcinoma secondary to metabolic-dysfunction associated steatotic liver disease

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World Journal of Hepatology 2024年第1期16卷 75-90页

作者： Matheus Truccolo Michalczuk Larisse Longo Melina Belén Keingeski Bruno de souza Basso Gabriel Tayguara Silveira Guerreiro Jessica T Ferrari joséEduardo Vargas Cláudia P Oliveira Carolina Uribe-Cruz Carlos Thadeu Schmidt Cerski Eduardo Filippi-Chiela Mário ReisÁlvares-da-Silva Division of Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Graduate Program in Gastroenterology and Hepatology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil Experimental Laboratory of Hepatology and Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Laboratory of Inflammatory and Neoplastic Cells Universidade Federal do ParanáParaná81530900Brazil department of Gastroenterology(LIM07) Faculdade de Medicina da Universidade de São PauloSão Paulo 01246903Brazil Facultad de Ciencias de la Salud Universidad Católica de las MisionesPosadasMisiones 3300Argentina Unit of Surgical Pathology Hospital de Clinicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil Center of Biotechnology Universidade Federal do Rio Grande do SulPorto Alegre 90035-003Rio Grande do SulBrazil department of Morphological Sciences Universidade Federal do Rio Grande do SulPorto Alegre 90.050-170Rio Grande do SulBrazil Conselho Nacional de desenvolvimento Científico e Tecnológico(CNPq) Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)ResearcherBrasília 71.605-001Brazil

BACKGROUND Prevalence of hepatocellular carcinoma(HCC)is increasing,especially in patients with metabolic dysfunctionassociated steatotic liver disease(MASLD).AIM To investigate rifaximin(RIF)effects on epigenetic/autophagy markers in *** Adult Sprague-Dawley rats were randomly assigned(n=8,each)and treated from 5-16 wk:Control[standard diet,water plus gavage with vehicle(Veh)],HCC[high-fat choline deficient diet(HFCD),diethylnitrosamine(deN)in drinking water and Veh gavage],and RIF[HFCD,deN and RIF(50 mg/kg/d)gavage].Gene expression of epigenetic/autophagy markers and circulating miRNAs were *** All HCC and RIF animals developed metabolic-dysfunction associated steatohepatitis fibrosis,and cirrhosis,but three RIF-group did not develop *** animals who developed HCC with those who did not,miR-122,miR-34a,tubulin alpha-1c(Tuba-1c),metalloproteinases-2(Mmp2),and metalloproteinases-9(Mmp9)were significantly higher in the *** opposite occurred with Becn1,coactivator associated arginine methyltransferase-1(Carm1),enhancer of zeste homolog-2(Ezh2),autophagy-related factor LC3A/B(Map1 Lc3b),and p62/sequestosome-1(p62/SQSTM1)-*** with controls,Map1 Lc3b,Becn1 and Ezh2 were lower in HCC and RIF-groups(P0.05).miR-122 was higher in HCC,and miR-34a in RIF compared to controls(P0.05).CONCLUSION RIF might have a possible beneficial effect on preventing/delaying liver carcinogenesis throu

关键词： Animal model Autophagy Epigenetic Hepatocellular carcinoma Metabolic dysfunction-associated steatotic liver disease Rifaximin

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Rainfall variability in the Brazilian northeast biomes and their interactions with meteorological systems and ENSO via CHELSA product

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Big Earth Data 2019年第4期3卷 315-337页

作者： Washington Luiz Félix Correia Filho joséFrancisco de Oliveira-Júnior Dimas de Barros Santiago paulo Miguel de Bodas Terassi paulo Eduardo Teodoro Givanildo de Gois Claudio joséCavalcante Blanco Pedro Henrique de Almeida souza Micejane da Silva costa Heliofábio Barros Gomes paulo joséDos Santos Institute of Atmospheric Sciences(ICAT) Federal University of Alagoas(UFAL)MaceióBrazil Postgraduate Program in Biosystems Engineering(PGEB) Federal Fluminense University(UFF)NiteróiBrazil Postgraduate Program in Meteorology Unidade Acadêmica de Ciências Atmosféricas(UACA)Federal Universityof Campina Grande(UFCG)Campina GrandeBrazil Postgraduate Program in Physical Geography University of São Paulo(USP)São PauloBrazil Federal University of Mato Grosso do Sul(UFMS) Chapadão do SulBrazil fSchool of Industrial Metallurgical Engineering of Volta Redonda Technological CenterUniversidade Federal Fluminense(UFF)Volta RedondaBrazil Faculty of Sanitary and Environmental Engineering(FAESA/ITEC) Federal University of Pará(UFPA)BelémBrazil

Brazilian biomes are home to a significant portion of the world’s biodiversity,with a total of 14%of existing species and still concentrate 20%of the world’s water ***,changes in biomes have a direct impact on rainfall patterns and water *** on this,the objective was to evaluate the variability of rainfall in the four existing biomes in the Northeast Brazil(NEB)and their interaction with the ENSO climate variability mode and regional scale meteorological systems via CHELSA *** this,monthly rainfall data were used from 1979 to 2013,with a spatial resolution of 1 km×1 km of the CHELSA product,and seasonal and annual rainfall patterns were extracted via *** was found that the rainy season in the Amazon,Caatinga and Cerrado biomes occurred between January and April,with varying intensities,except for the Atlantic *** seasonality patterns are associated with the NEB meteorological systems,with emphasis on ITCZ(all Biomes),UTCV(Amazon,Caatinga and Cerrado),Frontal Systems(extreme south of Caatinga,Cerrado and Atlantic Forest)and EWD/TWD in the(Atlantic Forest).In the inter-annual scale,the remarkable influence of ENSO was verified,mainly in the years 1983,1985,1989,1993,1998,2009 and *** is noteworthy that 1985 was the wettest year of the period,with a surplus in all biomes,while the driest year differs between the Amazon(1983),Atlantic Forest and Caatinga(1993)and Cerrado(2012)*** study via orbital product in NEB showed that anthropogenic processes and natural variability interfere with the forms of rain interception in the biomes and hence in rainfall patterns and water recycling in NEB.

关键词： Phytophysiognomy rainfall inter-annual variability water recycling climate change land use and occupation

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Influence of fire on woody vegetation of savanna and forest formations in the Cerrado biome

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林业研究:英文版 2023年第5期34卷 1207-1216页

作者： Aline das Gracas costa Fillipe Tamiozzo Pereira Torres Gumercindo souza Lima Fabiano Rodrigues de Melo Carlos Moreira Miquelino Eleto Torres Bruno Leao Said Schettini Vicente paulo Santana Neto AndréLuiz Lopes de Faria department of Forest Engineering Federal University of VicosaUFVVicosaMG 36570-900Brazil department of Geography Federal University of VicosaUFVVicosaMG 36570-900Brazil

Wildfires have environmental,economic,and social impacts,and can shape the landscape and benefit ecosystems such as the *** study evaluated the diversity,similarity,and floristic and structural differences of woody savanna and forest formations of the Cerrado,when affected and not affected by ***-eight 25-400m2 plots were randomly allocated and divided into Burnt Cerrado and Unburnt Cerrado,Burnt Forest,and Unburnt Forest,and divided into three levels of inclusion according to diameter class(smaller than 2 cm,2-5 cm and larger than5 cm).Species were identified,DBH and height measured,and phyto sociological parameters such as volume,diversity,and floristic similarity *** Cerrado had lower diversity,density,and dominance at all inclusion levels compared to the Unburnt Cerrado,and showed similarities between treatments at the inclusion *** Forest had smaller differences in diversity,density,and dominance than Unburnt *** formation was similar at level 1 of inclusion and in the total ***,it was dissimilar at lower *** lower density and diversity of species at the lowest levels of inclusion was associated with mortality from fire.

关键词： Biodiversity Brazil Burning Floristic Phytosociology

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Diversity of the endophytic filamentous fungal leaf community at different development stages of eucalyptus

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Journal of Forestry Research 2019年第3期30卷 1093-1103页

作者： paulo Sergio Balbino Miguel Fabio Balbino Miguel Bruno Coutinho Moreira Marcelo Nagem Valerio de Oliveira Julio Cesar delvaux Fernanda de souza Freitas Arnaldo Chaer Borges Maurcio Dutra costa departamento de Medicina e Enfermagem Universidade Federal de VicosaVicosaMinas Gerais 36570-000Brazil departamento de Quimica Universidade Federal de Juiz de ForaJuiz de ForaMinas Gerais 36036-300Brazil Colegiado de Engenharia Agronomica Universidade Federal do Vale do Sao FranciscoPetrolinaPernambuco 56300-990 Brazil departamento de Ciencias Basicas da Vida Campus Governador Valadares Universidade Federal de Juiz de Fora Governador ValadaresMinas Gerais 35012-140Brazil Coordenacao Geral de Ensino Pesquisa e Extensao Instituto Federal do Triangulo MineiroItuiutabaMinas Gerais 38035-200Brazil departamento de Microbiologia Instituto de Biotecnologia Aplicada aAgropecuariaUniversidade Federal de Vicosa VicosaMinas Gerais 36570-000Brazil

Fungal endophytic species inhabiting the leaves of eucalypts are capable of utilising leaf sugars and can influence both plant growth and health. Endophytic fungal symbionts can use simple soluble sugars in leaves as their main carbon source. This study set out to determine the diversity and distribution of the endophytic filamentous fungal leaf community in the hybrid Eucalyptus urograndis due to its economic importance. The fungal leaf community was characterised using denaturing gradient electrophoresis (DGGE) and correlated with levels of leaf nutrients and sugars throughout plant development. Sequencing of DGGE bands revealed the presence of Basidiomycota and Ascomycota phyla. Fourteen species and three genera of filamentous fungi were identified, and the population structure was affected by the plant developmental stage. Levels of K, Cu, N and Mn influenced communities from the clonal garden, whereas leaves in the field had higher glucose, fructose and sucrose. Many fungi were found to be specific to a certain development stages: Diplomitoporus crustulinus, Podosphaera tridactyla and Aspergillus restrictus to the clonal garden stage;Chaetomella acutiseta and Ascotricha chartarum to the shading stage;Erratomyces patelii and Saxomyces sp. to the shading output stage;Lepidostroma sp. and Saxomyces sp. to the dispatch stage;and Mycosphaerella populicola to the field stage. Teratosphaeria toledana and Teratosphaeria acidotherma were found at more than one developmental stage. Cladosporium sp. and Rhodosporidium fluviale colonized and persisted in plants at the dispatch and field stages. This is the first report of P. tridactyla, A. restrictus, E. patelii, Saxomyces and Lepidostroma sp. as endophytes in eucalipt.

关键词： Diversity 18S rRNA denaturing gradient electrophoresis(DGGE) Sequencing

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