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Calcium potentiates the effect of estradiol on PGF2α production in the bovine endometrium

Journal of Animal Science and Biotechnology 2015年第2期6卷 215-221页

作者： Claudia Maria Bertan Membrive pauline martins da cunha Flávio Vieira Meirelles Mario Binelli S?o Paulo State University Department of Animal Reproduction School of Veterinary Medicine and Animal Science University of S?o Paulo Department of Veterinary Medicine School of Animal Sciences and Food Engineering University of S?o Paulo

Background： Estradiol （E2） is required for luteolysis in cows and its injection stimulates prostaglandin F2α （PGF2α） release. The main goal of our study was to investigate the ability of endometrial explants and cells treated with E2 and the calcium ionophore （CI） A23187 to synthesize PGF2α. Results： Treatment with E2 in vivo resulted in a 48.4% increase of PGF2α production by endometrial explants treated in vitro with A23187. Production of PGF20 was better stimulated with A23187 at concentrations of 10^-6 and 10^-5 mol/L compared with other concentrations used. The concentration of PGF2α for untreated bovine endometrial cell cultures was 33.1 pg/mL, while for cultures treated with E2, A23187, or a combination of E2 and A23187, the PGF2α concentration was 32.5, 92.4 and 145.6 pg/mL, respectively. Conclusions： Treatment with A23187 tended to stimulate PGF20 production. In the presence of E2, A23187 significantly stimulated PGF20 synthesis. It appears that A23187 potentiates the effects of E2 with respect to synthesis of endometrial PGF2α in cattle.

关键词： Animal reproduction Cattle Estradiol Luteolysis PGF2α synthesis Reproductive physioloqy

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Subjectivity Versus Objectivity in Teaching Foreign Language

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Cultural and Religious Studies 2017年第3期5卷 134-141页

作者： Miguel Neneve Lusinilda Carla martins Federal University of Rondonia Rondonia Brazil

In this paper we propose to discuss the issue of subjectivity versus objectivity teaching practice of foreign language, especially English, in Brazil. Starting from the short story ＂The Parrot and Descartes＂ by pauline Melville, we argue that Cartesianism has influenced a view on education which tends to consider good and valuable what is ＂scientific＂, ＂objective＂ and ＂universal＂. The subjective and the local seem to be considered undesirable and unreliable. Brazilian scholars on the education field, such as Coracini and Souza are important support for our argument.

关键词： foreign language teaching subejctivity objectivity rationalism

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