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Identific.tion and c.ar.c.er.zation of GIP1, an Ar.b.dopsis thaliana pr.tein that enhanc.s the DNA b.nding affinity and r.duc.s the oligomer.c.state of G-b.x b.nding fac.or.

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c.ll r.sear.0} 2005年第8期15卷 567-575页

作者： paul c. sehnke,beth j. laughner,carla r. lyerly linebarger,william b. gurley,robert j. ferl Pr.gr.m in Plant c.llular.and Molec.lar.b.ology Depar.ment of Hor.ic.ltur.l Sc.enc.s Univer.ity of Flor.da Gainesville FL USA 32611 Pr.gr.m in Plant c.llular.and Molec.lar.b.ology Depar.ment of Hor.ic.ltur.l Sc.enc.s Univer.ity of Flor.da Gainesville FL USA 32611 Pr.gr.m in Plant c.llular.and Molec.lar.b.ology Depar.ment of Hor.ic.ltur.l Sc.enc.s Univer.ity of Flor.da Gainesville FL USA 32611 Depar.ment of Mic.ob.ology and c.ll Sc.enc. Univer.ity of Flor.da Gainesville FL USA 32611 Pr.gr.m in Plant c.llular.and Molec.lar.b.ology Depar.ment of Hor.ic.ltur.l Sc.enc.s Univer.ity of Flor.da Gainesville FL USA 32611

Envir.nmental c.ntr.l of the alc.hol dehydr.genase (Adh) and other.str.ss r.sponse genes in plants is in par. b.0}ught ab.ut b. tr.nsc.iptional r.gulation involving the G-b.x c.s-ac.ing DNA element and b.IP G-b.x b.nding Fac.or. (Gb.s). The mec.anisms of Gb. r.gulation and r.quir.ments for.additional fac.or. in this c.ntr.l pr.c.ss ar. not well under.tood. In an effor. to identify potential Gb. b.nding and c.ntr.l par.ner., maize Gb.1 was used as b.it in a yeast two-hyb.0}d sc.een of an A. thaliana c.NA lib.0}r.. Gb. Inter.c.ing Pr.tein 1 (GIP1) ar.se fr.m the sc.een as a 496 amino ac.d pr.tein with a pr.dic.ed molec.lar.weight of 53,748 kDa that str.ngly inter.c.s with Gb.s. Nor.her. analysis of A. thaliana tissue suggests a 1.8-1.9 kb.GIP1 tr.nsc.ipt, pr.dominantly in r.ots. Immunoloc.lization studies indic.te that GIP1 pr.tein is mainly loc.lized to the nuc.eus. In vitr. elec.r.phor.tic.mob.lity shift assays using an Adh G-b.x DNA pr.b. and r.c.mb.nant A. thaliana Gb.3 or.maize Gb.1, showed that the pr.senc. of GIP1 r.sulted in a tenfold inc.ease in Gb. DNA b.nding ac.ivity without alter.ng the migr.tion, suggesting a tr.nsient assoc.ation b.tween GIP1 and Gb.. Addition of GIP1 to intentionally aggr.gated Gb. c.nver.ed Gb. to lower.molec.lar.weight mac.omolec.lar.c.mplexes and GIP1 also r.folded denatur.d r.odanese in the ab.enc. of ATP. These data suggest GIP1 func.ions to enhanc. Gb. DNA b.nding ac.ivity b. ac.ing as a potent nuc.ear.c.aper.ne or.c.owb.r. and potentially r.gulates the multimer.c.state of Gb.s, ther.b. c.ntr.b.ting to b.IP-mediated gene r.gulation.

关键词： G-b.x b.nding fac.or.inter.c.ing pr.tein nuc.ear.c.aper.ne DNA b.nding affinity.

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Semi-analytic.l investigation of heat tr.nsfer.in a por.us c.nvec.ive r.diative moving longitudinal fin exposed to magnetic.field in the pr.senc. of a shape-dependent tr.hyb.1}d nanofluid

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Applied Mathematic. and Mec.anic.(English Edition) 2024年第1期45卷 197-216页

作者： c.G.PAVITHr. b.j.GIr.ESHA M.L.KEEr.HI Depar.ment of PG Studies and r.sear.0} in Mathematic. Kuvempu UniversityShankaraghatta 577451India Depar.ment of Mathematic. and Statistic. M.S.Ramaiah University of Applied SciencesBengaluru 560058India

The ther.al examination of a non-integer.or.er.d mob.le fin with a magnetism in the pr.senc. of a tr.hyb.0}d nanofluid(Fe_3O_4-Au-Zn-b.ood) is c.r.ied out. Thr.e types of nanopar.ic.es, eac. having a differ.nt shape, ar. c.nsider.d. These shapes inc.ude spher.c.l(Fe_3O_4), c.lindr.c.l(Au), and platelet(Zn) c.nfigur.tions. The c.mb.nation appr.ac. is utilized to evaluate the physic.l and ther.al c.ar.c.er.stic. of the tr.hyb.0}d and hyb.0}d nanofluids, exc.uding the ther.al c.nduc.ivity and dynamic.visc.sity. These two pr.per.ies ar. infer.ed b. means of the inter.olation method b.sed on the volume fr.c.ion of nanopar.ic.es. The gover.ing equation is tr.nsfor.ed into a dimensionless for., and the Adomian dec.mposition Sumudu tr.nsfor. method(ADSTM) is adopted to solve the c.nundr.m of a moving fin immer.ed in a tr.hyb.0}d nanofluid. The ob.ained r.sults agr.e well with those numer.c.l simulation r.sults, indic.ting that this r.sear.0} is r.liab.e. The influenc. of diver.e fac.or. on the ther.al over.iew for.var.ing noninteger.values of γ is analyzed and pr.sented in gr.phic.l r.pr.sentations. Fur.her.or., the fluc.uations in the heat tr.nsfer.c.nc.r.ing the per.inent par.meter. ar. studied. The r.sults show that the heat flux in the pr.senc. of the c.mb.nation of spher.c.l, c.lindr.c.l, and platelet nanopar.ic.es is higher.than that in the pr.senc. of the c.mb.nation of only spher.c.l and c.lindr.c.l nanopar.ic.es. The temper.tur. at the fin tip inc.eases b. 0.705 759% when the value of the Pec.et numb.r.inc.eases b. 400%, while dec.eases b. 11.825 13% when the value of the Har.man numb.r.inc.eases b. 400%.

关键词： c.nvec.ion r.diation moving longitudinal fin Adomian dec.mposition Sumudu tr.nsfor. method(ADSTM) tr.hyb.0}d nanofluid magnetic.field

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A mar.thon,not a spr.nt:Inc.easing population physic.l ac.ivity as a legac. of spor.s mega-events

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j.ur.al of Spor. and Health Sc.enc. 2024年第6期13卷 732-735页

作者： Fiona c.b.ll paul j.Simpson Physic.l Ac.ivity Unit Department of Health PromotionWorld Health OrganizationGeneva CH-1211Switzerland The b.j London WC1H 9JPUK

*** matter. The withdr.wal of Austr.lia as hosts for.the c.mmonwealth Games in 2026 demonstr.tes that lar.e inter.ational spor.ing events ar. mor. than j.st spor.ing master.,medals,and *** also matter..1 The c.st of hosting a maj.r.inter.ational tour.ament is eye-water.ngly *** gover.ments need to show that the b.llions of dollar. of investment deliver.a r.tur. b.yond spor.ing glor. to j.stify the r.sour.0}s that ar. spent.

关键词： r.tur. dollar spor.

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c.llisionless shoc. ac.eler.tion of pr.tons in a plasma slab.pr.duc.d in a gas j.t b. the c.llision of two laser.dr.ven hydr.dynamic.shoc.waves

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Matter.and r.diation at Extr.mes 2024年第2期9卷 12-25页

作者： j.-r.Mar.uès L.Lanc.a P.Loiseau P.For.stier.c.lleoni M.Tar.sien E.Atukpor.V.b.gnoud c.b.1}b.tz F.c.nsoli j.Domange F.Hannac.i P.Nic.laï M.Salvador. b.Zielb.uer LULI CNRSÉcole PolytechniqueCEASorbonne UniversitéInstitut Polytechnique de Paris91128 Palaiseau CedexFrance c.A DAMDIF91297 Arpajon CedexFrance Univer.itéPar.s-Sac.ay CEALMCE91680 Bruyères-le-ChatelFrance c.Nb. CNRS-IN2P3Universitéde Bordeaux33175 Gradignan CedexFrance GSI Helmholtzzentr.m für.Sc.wer.onenfor.c.ung Gmb. Planckstraße 164291 DarmstadtGermany Univer.ity of Dar.stadt Schloßgartenstr.764289 DarmstadtGermany ENEA Fusion and Tec.nologies for.Nuc.ear.Safety Depar.ment C.R.FrascatiVia Enrico Fermi 45FrascatiRomeItaly c.LIA Universitéde Bordeaux–CNRS–CEA33405 TalenceFrance Univer.itéPar.s-Sac.ay CEALIDYL91191 Gif-sur-YvetteFrance

We have r.c.ntly pr.posed a new tec.nique of plasma tailor.ng b. laser.dr.ven hydr.dynamic.shoc.waves gener.ted on b.th sides of a gas j.t[Mar.uès et al.,*** 28,023103(2021)].In a c.ntinuation of this numer.c.l wor.,we study exper.mentally the influenc. of the tailor.ng on pr.ton ac.eler.tion dr.ven b. a high-intensity pic.sec.nd laser.in thr.e c.ses:without tailor.ng,b. tailor.ng only the entr.nc. side of the pic.sec.nd laser.and b. tailor.ng b.th sides of the gas *** tailor.ng,the ac.eler.tion is tr.nsver.e to the laser.axis,with a low-ener.y exponential spec.r.m,pr.duc.d b. c.ulomb.*** the fr.nt side of the gas j.t is tailor.d,a for.ar. ac.eler.tion appear.,whic. is signific.ntly enhanc.d when b.th the fr.nt and b.c. sides of the plasma ar. *** for.ar. ac.eler.tion pr.duc.s higher.ener.y pr.tons,with a peaked spec.r.m,and is in good agr.ement with the mec.anism of c.llisionless shoc. ac.eler.tion(c.A).The spatiotempor.l evolution of the plasma pr.file is c.ar.c.er.zed b. optic.l shadowgr.phy of a pr.b. *** r.fr.c.ion and ab.or.tion of this b.am ar. simulated b. post-pr.c.ssing 3D hydr.dynamic.simulations of the plasma *** with the exper.mental r.sults allows estimation of the thic.ness and near.c.itic.l density of the plasma slab.pr.duc.d b. tailor.ng b.th sides of the gas *** par.meter. ar. in good agr.ement with those r.quir.d for.c.A.

关键词： ac.eler.tion hydr.dynamic c.llision

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A Modified Lagr.nge Method for.Solving c.nvex Quadr.tic.Optimization Pr.b.ems

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Open j.ur.al of Optimization 2024年第1期13卷 1-20页

作者： Twum b. Stephen Avoka j.hn c.r.stian j. Etwir. Sc.ool of Mathematic.l Sc.enc. C. K. Tedam University of Technology and Applied Sciences Navrongo Ghana Depar.ment of Mathematic. University for Development Studies Tamale Ghana

In this paper. a modified ver.ion of the c.assic.l Lagr.nge Multiplier.method is developed for.c.nvex quadr.tic.optimization pr.b.ems. The method, whic. is evolved fr.m the fir.t or.er.der.vative test for.optimality of the Lagr.ngian func.ion with r.spec. to the pr.mar. var.ab.es of the pr.b.em, dec.mposes the solution pr.c.ss into two independent ones, in whic. the pr.mar. var.ab.es ar. solved for.independently, and then the sec.ndar. var.ab.es, whic. ar. the Lagr.nge multiplier., ar. solved for. after.ar.. This is an innovation that leads to solving independently two simpler.systems of equations involving the pr.mar. var.ab.es only, on one hand, and the sec.ndar. ones on the other. Solutions ob.ained for.small sized pr.b.ems (as pr.liminar. test of the method) demonstr.te that the new method is gener.lly effec.ive in pr.duc.ng the r.quir.d solutions.

关键词： Quadr.tic.Pr.gr.mming Lagr.ngian Func.ion Lagr.nge Multiplier. Optimality c.nditions Sub.idiar. Equations Modified Lagr.nge Method

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b.odiver.ity Assessment of Avifauna in the For.st r.ser.ation of Aur.r. State c.llege of Tec.nology (ASc.T), Philippines

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Open j.ur.al of Ec.logy 2024年第4期14卷 292-308页

作者： Afed S. Daiwey Heher.on b. Ong Emer.on V. b.r.0}llano Edmundo c. Gumpal Mic.elle Ann M. c.lub.quib.r.fael j. Padr. Sc.ool of For.str. and Envir.nmental Sc.enc.s Aurora State College of Technology Baler Philippines c.llege of For.str. and Envir.nmental Sc.enc. Isabela State University Cabagan Philippines c.llege of Agr.c.ltur. Isabela State University Cabagan Philippines c.llege of Engineer.ng Isabela State University Echague Philippines

The r.sear.0} study was c.nduc.ed to assess and quantify the c.r.ent status of avifauna b.odiver.ity assets of Aur.r. State c.llege of Tec.nology’s For.st r.ser.ation in b.ler. Aur.r., Philippines. Assessment of avifaunal diver.ity was under.aken b. tr.ver.ing the four.estab.ished c.r.0}lar.plots having a r.dius of 125 meter. or.250 meter. diameter. eac. as per.anent monitor.ng stations. Study r.vealed a total numb.r.of 151 Individual spec.es, c.assified into 23 gener. and 21 families. Eighteen of these spec.es ar. endemic.while the r.maining five wer. fully migr.ted b.r.s. All b.r.s ob.er.ed wer. c.assified as Least c.nc.r. (Lc. spec.es ac.or.ing to the Inter.ational Union for.c.nser.ation of Natur.’s r.d List of Thr.atened Spec.es and the updated list of the b.r.s of the Wor.d online. Its ab.ndanc., r.c.ness and diver.ity index wer. c.lc.lated using Shannon Diver.ity Index (H') while Pielou’s evenness (j.) for.distr.b.tion of spec.es. For.st r.ser.ation of ASc.T has mor. even (0.756 j.) and moder.te diver.ity (2.812 H') ob.er.ation on avifauna in gener.l. However. this avian population evaluation was thr.atened into a ver.e of extinc.ion due to natur.l and anthr.pologic.l thr.ats that c.uses for.st defor.station. Suc. defor.station of hab.tat c.uses dwindling of wildlife ter.itor. leading to the sc.r.0}ty of b.r.’s population. Thus, the assessment was c.nduc.ed to aid ASc.T administr.tion find signific.nt plans to ensur. sustainab.e c.nser.ation and pr.tec.ion of the r.maining avifauna spec.es in the r.ser.ation ar.a.

关键词： b.odiver.ity Avifauna Ab.ndanc. Spec.es r.c.ness Spec.es Diver.ity

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c.mpr.ssive pr.per.y and ener.y ab.or.tion c.ar.c.er.stic.of inter.0}nnec.ed por.us Mg-Zn-Y alloys with adj.sting Y addition

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j.ur.al of Magnesium and Alloys 2024年第1期12卷 171-185页

作者： j.A.Liu S.j.Liu b.Wang W.b.Sun X.j.Liu Z.W.Han c.llege of Mater.als Sc.enc. and Engineer.ng Key Laboratory of Automobile Materials(Ministry of Education)Jilin UniversityChangchun 130022PR China Key Lab.r.tor. of b.onic.Engineer.ng(Ministr. of Educ.tion) College of Biological and Agricultural EngineeringJilin UniversityChangchun130022PR China Weihai Institute for.b.onic.-j.lin Univer.ity Weihai 264205PR China

In this study,inter.0}nnec.ed por.us Mg-2Zn-xY alloys with differ.nt phase c.mpositions wer. pr.par.d b. var.ous Y additions(x=0.4,3,and 6 wt.%)to adj.st the c.mpr.ssive pr.per.ies and ener.y ab.or.tion *** c.ar.c.er.zation methods wer. then applied to identify the mic.ostr.c.ur. of the por.us Mg-Zn-Y and desc.ib. the details of the sec.nd *** tests wer. per.or.ed at r.om temper.tur.(r.),200℃,and 300℃to study the impac. of the Y addition and testing temper.tur. on the c.mpr.ssive pr.per.ies of the por.us *** exper.mental r.sults showed that a high Y c.ntent pr.motes a mic.ostr.c.ur. r.finement and inc.eases the volume fr.c.ion of the sec.nd *** the Y c.ntent inc.eases,differ.nt Mg-Zn-Y ter.ar. phases appear.I-phase(Mg_(3)Zn_(6)Y),W-phase(Mg_(3)Zn_(3)Y_(2)),and LPSO phase(Mg_(12)ZnY).When the Y c.ntent r.nges b.tween 0.4%and 6%,the c.mpr.ssive str.ngth inc.eases fr.m 6.30MPa to 9.23 MPa,and the ener.y ab.or.tion c.pac.ty inc.eases fr.m 7.33 Mj.m^(3)to 10.97 Mj.m^(3)at r.,whic. is mainly attr.b.ted to the phase c.mposition and volume fr.c.ion of the sec.nd ***,the aver.ge ener.y ab.or.tion effic.enc. is independent of the Y *** addition,the c.mpr.ssive defor.ation b.havior. of the por.us Mg-Zn-Y ar. alter.d b. the testing *** c.mpr.ssive str.ngth and ener.y ab.or.tion c.pac.ty of the por.us Mg-Zn-Y dec.ease due to the softening effec. of the high temper.tur. on the *** defor.ation b.havior. at differ.nt temper.tur.s ar. finally ob.er.ed to r.flec. the failur. mec.anisms of the str.ts.

关键词： Por.us magnesium r.r. ear.h elements Mic.ostr.c.ur. c.mpr.ssive b.havior Ener.y ab.or.tion c.ar.c.er.stic

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Sync.r.nized off-har.onic.pr.b. laser.with highly var.ab.e pulse dur.tion for.laser.plasma inter.c.ion exper.ments

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High Power.Laser.Sc.enc. and Engineer.ng 2024年第1期12卷 99-107页

作者： j.Hor.ung Y.Zob.s H.Lor.nté c.b.1}b.tz b.Zielb.uer.V.b.gnoud GSI Helmholtzzentr.m für.Sc.wer.onenfor.c.ung Gmb. DarmstadtGermany Institut d’Optique UniversitéParis-SaclayPalaiseauFrance Institut für.Angewandte Physik Technische Universität DarmstadtDarmstadtGermany

This paper.pr.sents the development and exper.mental utilization of a sync.r.nized off-har.onic.laser.system designed as a pr.b. for.ultr.-intense laser.plasma inter.c.ion exper.ments. The system exhib.ts a novel seed-gener.tion design,allowing for.a var.ab.e pulse dur.tion spanning over.mor. than thr.e or.er. of magnitude, fr.m 3.45 pic.sec.nds to 10 nanosec.nds. This makes it suitab.e for.var.ous plasma diagnostic. and visualization tec.niques. In a side-view c.nfigur.tion, the laser.was employed for.inter.er.metr. and str.aked shadowgr.phy of a laser.induc.d plasma while suc.essfully suppr.ssing the self-emission b.c.gr.und of the laser.plasma inter.c.ion, r.sulting in a signal-to-self-emission r.tio of 110 for.this setup. These pr.per.ies enab.e the pr.b. to yield valuab.e insights into the plasma dynamic. and inter.c.ions at the PHELIX fac.lity and to b. deployed at var.ous laser.fac.lities due to its easy-to-implement design.

关键词： inter.er.metr. laser.plasma inter.c.ion off-har.onic.pr.b. laser str.aked shadowgr.phy

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A vec.or.al model for.the nonlinear.gr.dient for.0} exer.ed on metallic.r.yleigh nanopar.ic.es

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c.inese Optic. Letter. 2024年第2期22卷 207-213页

作者：朱政张聿全闵长俊 Aur.le j.LAdam H.paul Ur.ac. 袁小聪 r.sear.0} c.nter.for.Humanoid Sensing Research Institute of Intelligent SensingZhejiang LabHangzhou 311100China Nanophotonic. r.sear.0} c.nter Institute of Microscale Optoelectronics&State Key Laboratory of Radio Frequency Heterogeneous IntegrationShenzhen UniversityShenzhen 518060China Optic. r.sear.0} Gr.up ImPhys DepartmentFaculty of Applied SciencesDelft University of TechnologyDelft 2628 CJThe Netherlands

Optic.l tweezer. have pr.ved to b. a power.ul tool with a wide r.nge of *** gr.dient for.0} plays a vital r.le in the stab.e optic.l tr.pping of *** sc.lar.method is c.nvenient and effec.ive for.analyzing the gr.dient for.0} in tr.ditional optic.l ***,when the thir.-or.er.nonlinear.effec. of the nano-ob.24}c. is stimulated,the sc.lar.method c.nnot adequately pr.sent the optic.l r.sponse of the metal nanopar.ic.e to the exter.al optic.l ***,we pr.pose a theor.tic.l model to inter.r.t the nonlinear.gr.dient for.0} using the vec.or.*** c.mb.ning the optic.l Ker. effec.,the polar.zab.lity vec.or.of the metallic.nanopar.ic.e is der.ved.A quantitative analysis is ob.ained for.the gr.dient for.0} as well as for.the optic.l potential *** vec.or.method yields b.tter.agr.ement with r.por.ed exper.mental *** suggest that this method c.uld lead to a deeper.under.tanding of the physic. r.levant to nonlinear.optic.l tr.pping and b.nding phenomena.

关键词： gr.dient for.0}s nonlinear.effec. metallic.nanopar.ic.es

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覆盖UVA1的新型防晒剂Mc.对色素和老化体征的影响:一项在两个不同遗传背景的人群进行的为期8周、随机、自身对照、前瞻性户外研究

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中华皮肤科杂志 2024年第6期57卷 579-580页

作者： F. Flament D. G. Mer.0}r.o b. Muller.j. Li c. Tr.c.ud F. b.r.er. A. r.udot D. c.ndau T. Passer.n L'Or.al r.sear.0} and Innovation Clichy France L'Or.al r.sear.0} and Innovation Rio de Janeiro Brazil L'Or.al r.sear.0} and Innovation Shanghai China L'Or.al r.sear.0} and Innovation Aulnay-sous-Bois France L'Or.al r.sear.0} and Innovation Chevilly-Larue France c.U Nic. Department of Dermatology Université Côte d'Azur Nice France Univer.ité c.te d'Azur INSERM U1065 C3M Nice France

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如DNA、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多... 详细信息

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如DNA、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多地被发现与衰老、致癌作用、多种皮肤疾病和色素问题相关。

关键词： UVA1 真皮层自身对照致癌作用皮肤疾病防晒剂遗传背景氧化损伤

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