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Children’s growth and motor development following a severe burn:a systematic review

Burns & Trauma 2023年第1期11卷 349-360页

作者： maxime D.Cuijpers martin G.A.Baartmans paul p.m.van zuijlen Johannes C.F.Ket Anouk pijpe Red Cross Hospital Burn Centre BeverwijkVondellaan 13BeverwijkThe Netherlands Amsterdam University medical Centre Location VU University Medical CentreDepartment of PlasticReconstructiveand Hand SurgeryAmsterdam Movement Sciencesde Boelelaan 1117AmsterdamThe Netherlands Association of Dutch Burn Centres Zeestraat 27-29BeverwijkThe Netherlands maasstad Hospital Department of PaediatricsMaasstadweg 21Rotterdam3079 DZThe Netherlands Red Cross Hospital Department of Plastic SurgeryReconstructive and Hand SurgeryVondellaan 13Beverwijk1942 LEThe Netherlands paediatric Surgical Centre Emma Children’s HospitalAmsterdam UMCUniversity of AmsterdamVrije UniversiteitMeibergdreef 9Amsterdam1105 AZThe Netherlands medical Library Vrije Universiteitde Boelelaan 1117AmsterdamThe Netherlands

Background:The epidemiological data on post-burn growth,body composition and motor devel-opment is ambiguous and *** aim of this systematic review was therefore to summarize the current body of evidence on post-burn growth,body composition and motor development in ***:A literature search was conducted in pubmed,EmBASE and Web of Science up to march *** considered observational studies that reported(1)metrics on weight,height,body composition,bone mineral content,bone mineral density or motor development,in(2)paediatric burn patients and(3)published in a peer-reviewed ***:A total of 16 studies were *** of the included studies used quantitative methods,but with differing methodology:prospective cohort studies(n=8),retrospective chart reviews(n=3),case-control studies(n=2),cross sectional studies(n=2)and a retrospective cohort study(n=1).When combined,the included studies represented 2022 paediatric burn patients,with a mean age of 7.7(±3.2)*** average burn sizewas 52.8%(±12.7)of the total body surface *** outcome measures included weight(n=12),height(n=7),muscular strength(n=4),bone mineral content(n=5),bone mineral density(n=5),body mass index(n=3),fat mass(n=5),lean body mass(n=7)and fine and gross motor development(n=1).Conclusions:Following an initial decline,patients’growth and motor development started to recover during the first or second year ***,burns may have a profound and prolonged effect on the paediatric burn patients’muscular strength,bone mineral content and lean body *** should be noted that the vast majority of studies included only patients with burns covering≥30%total body surface *** evidence presented in this review may thus not be representative of the whole paediatric burn population.

关键词： Burns Children Weight Height Bone muscle motor function

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Skin bioprinting:the future of burn wound reconstruction?

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Burns & Trauma 2019年第1期7卷 25-36页

作者： mathew Varkey Dafydd O.Visscher paul p.mvan zuijlen Anthony Atala James J.Yoo Wake Forest Institute for Regenerative medicine Wake Forest School of MedicineMedical Center BoulevardWinston-SalemNC 27101USA Department of plastic Reconstructive and Hand SurgeryAmsterdam University Medical Center1081HVAmsterdamThe Netherlands Amsterdam movement Sciences AmsterdamThe Netherlands Burn Center Red Cross Hospital1942LEBeverwijkThe Netherlands Association of Dutch Burn Centres 1942LEBeverwijkThe Netherlands

Burns are a significant cause of trauma,and over the years,the focus of patient care has shifted from just survival to facilitation of improved functional ***,burn treatment,especially in the case of extensive burn injuries,involves surgical excision of injured skin and reconstruction of the burn injury with the aid of skin *** skin substitutes do not contain all skin cell types and do not facilitate recapitulation of native skin ***-dimensional(3D)bioprinting for reconstruction of burn injuries involves layer-by-layer deposition of cells along with scaffolding materials over the injured *** bioprinting can be done either in situ or in *** these approaches are similar except for the site of printing and tissue *** are technological and regulatory challenges that need to be overcome for clinical translation of bioprinted skin for burn ***,the use of bioprinting for skin reconstruction following burns is promising;bioprinting will enable accurate placement of cell types and precise and reproducible fabrication of constructs to replace the injured or damaged ***,3D bioprinting is a very transformative technology,and its use for wound reconstruction will lead to a paradigm shift in patient *** this review,we aim to introduce bioprinting,the different stages involved,in vitro and in vivo skin bioprinting,and the various clinical and regulatory challenges in adoption of this technology.

关键词： Bioprinting Skin Burns Reconstruction

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3D printing of patient-specific neck splints for the treatment of post-burn neck contractures

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Burns & Trauma 2018年第2期6卷 155-157页

作者： Dafydd O.Visscher Sjoerd te Slaa marielle E.Jaspers marloes van de Hulsbeek Jorien Borst Jan Wolff Tymour Forouzanfar paul p.van zuijlen Department of plastic Reconstructive and Hand SurgeryAmsterdam Movement SciencesVU University Medical Centerde Boelelaan 11171081HV Amsterdamthe Netherlands 3D InnovationLab VU University Medical CenterAmsterdamthe Netherlands Department of Oral and maxillofacial Surgery/Oral pathology VU University Medical CenterAmsterdamthe Netherlands Department of medical Technology VU University Medical CenterAmsterdamthe Netherlands Department of plastic Reconstructive and Hand Surgery/Burn CenterRed Cross HospitalBeverwijkthe Netherlands Department of Occupational Therapy Red Cross HospitalBeverwijkthe Netherlands.

Dear Editor,Burn scar contracture is a common problem in healing burn wounds of the neck. It can cause both pain and dysfunction if not treated adequately (1)The treatment of such wounds often involves a combination of surgery and splinting therapy (2)A variety of splints, including the thermoplastic static neck splint [3], the Watusi collar [4], manually fabricated splints, and pre-fabricated splints such as the philadelphia collar have been used for the management of scar contractures. However, each type of splint has its own advantages and disadvantages, and none of these splints seem to reduce the need for skin reconstruction nor delays the time until surgical re-construction [5].

关键词： Neck burns Contracture 3D printing Neck splint Clinical Optical 3D scanning

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