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Anticancer property of sediment actinomycetes against mCF-7 and mDA-mB-231 cell lines

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Asian Pacific Journal of Tropical Biomedicine 2012年第2期2卷 92-96页

作者： Ravikumar S Fredimoses m Gnanadesigan m School of marine Sciences Department of Oceanography and Coastal Area StudiesAlagappa UniversityThondi CampusThondi-623 409Ramanathapuram District Department of Biotechnology K.S.Rangasamy College of Arts & ScienceThiruchengodu- 637209Namakkal District

ObjectiveTo investigate the anticancer property of marine sediment actinomycetes against two different breast cancer cell *** vitro anticancer activity was carried out against breast (mCF-7 and mDA-mB-231) cancer cell lines. Partial sequences of the 16s rRNA gene, phylogenetic tree construction, multiple sequence analysis and secondary structure analysis were also carried out with the actinomycetes *** the selected five actinomycete isolates, ACT01 and ACT02 showed the IC50 value with (10.13±0.92) and (22.34±5.82) μg/mL concentrations, respectively for mCF-7 cell line at 48 h, but ACT01 showed the minimum (18.54±2.49 μg/mL) level of IC50 value with mDA-mB-231 cell line. Further, the 16s rRNA partial sequences of ACT01, ACT02, ACT03, ACT04 and ACT05 isolates were also deposited in NCBI data bank with the accession numbers of GQ478246, GQ478247, GQ478248, GQ478249 and GQ478250, respectively. The phylogenetic tree analysis showed that, the isolates of ACT02 and ACT03 were represented in group I and III, respectively, but ACT01 and ACT02 were represented in group II. The multiple sequence alignment of the actinomycete isolates showed that, the maximum identical conserved regions were identified with the nucleotide regions of 125 to 221st base pairs, 65 to 119th base pairs and 55, 48 and 31st base pairs. Secondary structure prediction of the 16s rRNA showed that, the maximum free energy was consumed with ACT03 isolate (-45.4 kkal/mol) and the minimum free energy was consumed with ACT04 isolate (?7.6 kkal/mol).ConclusionsThe actinomycete isolates of ACT01 and ACT02 (GQ478246 and GQ478247) which are isolated from sediment sample can be further used as anticancer agents against breast cancer cell lines.

关键词： Actinomycetes Breast cancer mCF–7 mDA–mB–231 Phylogenetic tree Anticancer property multiple sequence analysis Secondary structure analysis Sediment Anticaner agent Cell line

成人无症状肝脂肪变性的冠状动脉CT血管成像

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国际医学放射学杂志 2022年第1期 110-111页

作者： m.m.Yu X.L.Tang h.Jin S.Yang h.Yun Q.B.Wang 李鹏飞

摘要冠状动脉CT血管成像（CCTA）对成人无症状肝脂肪变性（hS）的长期预后价值尚不清楚。目的评估CCTA对成人无症状hS的长期预后价值。材料与方法前瞻性纳入

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转移灶与卵巢癌标准化摄取比值对晚期浆液性卵巢上皮癌的预后价值

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国际医学放射学杂志 2018年第1期 109-110页

作者： h.h.Chung m.Lee h.S.Kim J.W.Kim N.h.Park Y.S.Song 黄黎香 Department of Obstetrics and Gynaecology Cancer Research InstituteSeoul National University College of Medicine

摘要目的评价术前PET/CT经18F-FDG摄取测得的转移灶代谢活性对晚期浆液性卵巢上皮癌(EOC)病人的预后价值。方法评估国际妇产科协会(FIGO)标准的卵巢癌Ⅲ、Ⅳ

关键词：卵巢上皮癌转移灶卵巢癌浆液性预后价值

Effects of heat Treatment on hardness and Dry Wear Properties of a Semi-Solid Processed Fe-27 wt pct Cr-2.9 wt pct C Cast Iron

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Journal of materials Science & Technology 2008年第3期24卷 330-334页

作者： A.Wiengmoon T.Chairuangsri N.Chomsang N.Poolthong J.T.h.Pearce Department of Physics Faculty of ScienceNaresuan University Department of Industrial Chemistry and Electron microscopy Research and Service Center Faculty of ScienceChiang Mai University Department of Physics Faculty of ScienceChiang Mai University Division of materials Technology School of EnergyEnvironmental and MaterialsKing Mongkut's University of Technology Thonburi National metal and materials Technology Center

EfFects of heat treatments on hardness and dry wear properties of a semi-solid processed Fe-26.96 wt pct Cr- 2.91 wt pct C cast iron were studied. heat treatments included tempering at 500℃, destabilisation at 1075℃ and destabilisation at 1075℃ plus tempering at 500℃, all followed by air cooling. Electron microscopy revealed that, in the as-cast condition, the primary proeutectic austenite was round in shape while the eutectic m7C3 carbide was found as radiating clusters mixed with directional clusters. Tempering did not change the microstructure significantly when observed by scanning or transmission electron microscopy. Destabilisation followed by air cooling led to a precipitation of secondary m23C6 carbide and a transformation of the primary austenite to martensite. Precipitation behaviour is comparable to that observed in the conventionally cast iron. Tempering after destabilisation resulted in a higher amount of secondary carbide precipitation within the tempered martensite in the eutectic structure. Vickers macrohardness and microhardness in the proeutectic zones were measured. Dry wear properties were tested by using a pin-on-disc method. The maximum hardness and the lowest dry wear rate were obtained from the destabilisation-plus-tempering heat treatment due to the precipitation of secondary carbides within the martensite matrix and a possible reduction in the retained austenite.

关键词： Semi-solid process high chromium cast iron heat treatment hardness Wear

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现代政治学

现代政治学

比较CT和mRI在鉴别非弥漫型自身免疫性胰腺炎与胰腺导管腺癌的诊断效能

1964年

作者： G·m·卡德 J·h·赫兹李诰译

来源：汇雅图书（南通市图书馆... 评论

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国际医学放射学杂志 2019年第1期 127-128页

作者： S.Lee J.h.Kim S.Y.Kim J.h.Byun h.J.Kim m.h.Kim 汪俊萍 Department of Radiology and Research Institute of Radiology University of Ulsan College of MedicineAsan Medical Center

摘要目的采用阅片者自身对照的方式比较CT和mRI在鉴别非弥漫型自身免疫性胰腺炎(AIP)与胰腺导管腺癌(PDA)的诊断效能。方法本研究共纳入61例非弥漫型AIP

关键词：自身免疫性胰腺炎胰腺导管腺癌诊断效能 mRI 弥漫型 CT

INFLUENCE OF TOP- TEmPERATURE OF ThERmAL CYCLE ON ThERmAL STRESS/STRAIN AND ThERmAL FATIGUE BEhAVIOR OF PURE IRON

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Acta metallurgica Sinica(English Letters) 1999年第5期12卷 852-855页

作者： J.h.Liu 1) and S.h.Jiang 1) and m.Yao 2) 1) Department of mechanical Engineering, Engineering college, Yangzhou University, Yangzhou 225009, China 2) Department of material Science, Yanshan University, Qinhuangdao 066000, China

By using a self-made thermal fatigue test machine of outer-constraint mode, the influence of top-temperature of thermal cycle T t on thermal stress-strain and thermal fatigue behavior of an industrial pure iron was investigated. The T t was varied from stress/strain 773K to 1073K. The results show that, increasing of T t , the thermal stress-strain cycles can be classified into four types, they are: compressive stress cycle; compressive strain-tensile stress cycle; compressive strain-tensile stress cycle than changing to compressive tensile plastic strain cycle; and finally, compressive tensile plastic strain cycle. It is also revealed that certain relationship does exist between thermal fatigue life and characteristics of thermal stress/strain cycle. When compressive tensile plastic strain cycle were appear by increasing of T t , thermal fatigue life decreasing rapidly. The concept of thermal fatigue transition temperature, and determining method were put up in this thesis.

关键词： thermal fatigue thermal stress-strain

microstructural and mechanical behavior of blended powder semisolid formed Al7075/B_4C composites under different experimental conditions

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Transactions of Nonferrous metals Society of China 2018年第7期28卷 1298-1310页

作者： A.JAVDANI A.h.DAEI-SORKhABI Department of mechanical Engineering Tabriz Branch Islamic Azad University

This work aimed to fabricate B4C reinforced aluminum matrix composites via blended powder semisolid forming that is an implementation of the benefits of semisolid forming to the powder metallurgy. Al7075 elements were incrementally added to ethanol solution under mechanical mixing. Al7075 constituents and B4C particles were blended in a high energy ball mill. Cold compacted Al7075/B4C blends were pressed at semisolid state. The effects of the size of the matrix（20, 45 and 63 μm）, reinforcing volume fraction（5%, 10% and 20%） and semisolid compaction pressure（50 and 100 mPa） on the morphology, microstructure, density, hardness, compression and bending strength were thoroughly analyzed. Experimental results revealed that the highest microstructural uniformity was achieved when large B4C particles（45 μm） were distributed within the small particles（20 μm） of the matrix phase. Composites with matrix particles larger than reinforcing phase indicated agglomerations in loadings more than 10%（volume fraction）. Agglomerated regions resisted against penetration of the liquid phase to the pores and lowered the density and strength of these composites. Composites with 20 μm Al7075 and 20%（volume fraction） 45 μm B4C powder pressed under 100 mPa exhibited the highest values of hardness（hV 190） and compressive strength（336 mPa）.

关键词： blended powder mechanical alloying semisolid forming B4C aluminum matrix composite

Electrical Conductivity and Infra Red of CaTiO_3 Doped with CuO

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Journal of materials Science & Technology 2001年第6期17卷 667-669页

作者： F.F.hammad and m.Sh.Khalil Department of Inorganic Chemistry, National Research Centre, Dokki, Cairo, Egypt A. h. Salama Department of Physical Chemistry, National Research Centre, Dokki, Cairo, Egypt [manuscript rece Natl Res Ctr Dept Inorgan Chem Cairo Egypt Natl Res Ctr Dept Phys Chem Cairo Egypt

The electrical conductivity of pure CaTiO3 and that containing 0.5~5.0 mole fraction CuO as dopant were measured in the temperature range 291~773 K. The conductivity values varied as a function of temperature and dopant concentration. The activation energy in the lower temper- ature range depended on the impurity content while in the high temperature range it indicated a value of energy gap width. The infrared absorption spectra in the range of 100~4000 cm-1 revealed the presence of two main bands at 340 and 570 cm-1 which were assigned to Ti06 oc- tahedral normal mode. Bands in the range of 106~270 cm-1 were due to the vibration of anion TiO3-2. Some bands were observed at higher values due to the presence of lattice imperfections. There was a slight shift in band position with increasing dopant concentration which favors the formation of orthorhombic modification.

关键词： Electrical Conductivity and Infra Red of CaTiO3 Doped with CuO TiO In