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The WAK-like protein RFO1 acts as a sensor of the pectin methylation status in Arabidopsis cell walls to modulate root growth and defense

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Molecular Plant 2023年第5期16卷 865-881页

作者： Apolonio I.Huerta Gloria Sancho-Andre´s Juan Carlos Montesinos Javier Silva-Navas Sole`ne Bassard Corinne pau.Roblot Christopher Kesten Rudolf Schlechter Susanne Dora Temurkhan Ayupov Je´rome Pelloux^ Julia Santiago Clara Sa´nchez-Rodrı´guez ETH Zurich Institute of Molecular Plant Biology(D-BIOL)ZurichSwitzerland University of Lausanne Department of Plant Molecular BiologyLausanneSwitzerland UMRT INRAE 1158 BioEcoAgro–BIOPI Biologie des Plantes et Innovation Universite´de Picardie33 Rue St Leu80039 AmiensFrance Present address:Lonza AG VispVisSwitzerland Present address:Institute of Microbiology Freie Universitat BerlinBerlinGermany Present address:Institute of Molecular and Clinical Ophthalmology-Basel BaselSwitzerland Present address:Centro de Biotecnologı´a y Geno´mica de Plantas Universidad Polite´cnica de Madrid(UPM)–Instituto Nacional de Investigacio´n y Tecnologı´a Agraria y Alimentaria(INIA/CSIC)Campus de Montegancedo UPM28223 Pozuelo de Alarco´nSpain

Most organisms adjust their development according to the environmental *** the majority,this implies the sensing of alterations to cell walls caused by different *** the relevance of this process,few molecular players involved in cell wall sensing are known and ***,we show that the wall-associated kinase-like protein RESISTANCE TO FUSARIUM OXYSPORUM 1(RFO1)is required for plant growth and early defense against Fusarium oxysporum and functions by sensing changes in the pectin methylation levels in the cell *** RFO1 dwell time at the plasma membrane is affected by the pectin methylation status at the cell wall,regulating MITOGEN-ACTIVATED PROTEIN KINASE and gene *** show that the extracellular domain of RFO1 binds de-methylated pectin in vitro,whose distribution in the cell wall is altered during *** *** analyses also indicate that RFO1 is required for the BR-dependent plant growth alteration in response to inhibition of pectin de-methyl-esterase activity at the cell ***,our work demonstrates that RFO1 is a sensor of the pectin methylation status that plays a unique dual role in plant growth and defense against vascular pathogens.

关键词： alterations walls pectin

Physiotherapy as a Way to Maintain Vaginal Health during Menopau.e

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Advances in Sexual Medicine 2017年第2期7卷 97-104页

作者： Mercedes Blanquet Rochera Cristina Salar Andreu Yolanda Castellano Madrid Karima Bouallalene Enrique Montero pau IM Clinic Fisio 7 Rehabilitation Centre University of Manresa Manresa Spain CEU Cardenal Herrera University Valencia Spain Autonomous University of Barcelona Barcelona Spain Fisio 7 Rehabilitation Centre Manresa Spain A Punto Clinic Valencia Spain

The majority of women will experience some or most of the menopau.e symptoms in their life. Thais time in women’s life is associated with a reduction in estrogen levels which leads to physiological changes that affect different organ systems. In the urogenital tract, these changes usually cause vulvar and vaginal atrophy, affecting a vaginal health of women and decreasing their quality of life. Also, there is a reduction in vaginal moisture and loss of tissue elasticity. Besides, other organ systems are involved and they can also negatively impact normal vaginal physiology. These evolutional changes frequently lead to bothersome symptoms that can negatively impact a woman’s vaginal health and the quality of life. The role of pelvic floor physiotherapy is to improve the tone and strength of the muscle fibres in order to achieve the increase of motor units, improve muscle elasticity and to increase the muscle mass which will help to alleviate menopau.e symptoms.

关键词： Menopau.e Vaginal Health Physiotherapy Pelvic Floor

Exploiting the diversity of tomato:the development of a phenotypically and genetically detailed germplasm collection

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Horticulture Research 2020年第1期7卷 1941-1954页

作者： Estefanía Mata-Nicolás Javier Montero-pau.Esther Gimeno-Paez Víctor Garcia-Carpintero Peio Ziarsolo Naama Menda Lukas A.Mueller JoséBlanca Joaquín Cañizares Esther van der Knaap María JoséDíez Instituto Universitario de Conservación y Mejora de la Agrodiversidad Valenciana.COMAV.Universitat Politècnica de València ValenciaSpain Department of Biochemistry and Molecular Biology Universitat de ValènciaValenciaSpain Boyce Thompson Institute IthacaNYUSA Institute of Plant Breeding Genetics and GenomicsUniversity of GeorgiaGeorgiaGAUSA Department of Horticulture University of GeorgiaGeorgiaGAUSA

A collection of 163 accessions,including Solanum pimpinellifolium,Solanum lycopersicum *** and Solanum lycopersicum ***,was selected to represent the genetic and morphological variability of tomato at its centers of origin and domestication:Andean regions of Peru and Ecuador and *** collection is enriched with *** *** from the Amazonian region that has not been analyzed previously nor used *** collection has been morphologically characterized showing diversity for fruit,flower and vegetative *** genomes were sequenced in the Varitome project and are publicly available(***/projects/varitome).The identified SNPs have been annotated with respect to their impact and a total number of 37,974 out of 19,364,146 SNPs have been described as high impact by the SnpEeff *** has shown associations for different traits,demonstrating the potential of this collection for this kind of *** have not only identified known QTLs and genes,but also new regions associated with traits such as fruit color,number of flowers per inflorescence or inflorescence *** speed up and facilitate the use of this information,F2 populations were constructed by crossing the whole collection with three different *** F2 collection is useful for testing SNPs identified by GWAs,selection sweeps or any other candidate *** data is available on Solanaceae Genomics Network and the accession and F2 seeds are freely available at COMAV and at TGRC *** these resources together make this collection a good candidate for genetic studies.

关键词： germplasm collection traits

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PC的冬天来了吗？

现代计算机（中旬刊） 2001年第12期 12-14页

作者： pau.

Preventive care for burnout: General practitioner pilot program in Barcelona

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Health 2013年第6期5卷 24-31页

作者： Jorge L. Tizón pau.Gràcia Anna Larripa Jordi Artigue Josep Casajuana Mental Health Prevention and Early Attention Team for Patients at Risk for Psychosis (EAPPP) Catalan Health Institute (Institut Catalá de la Salut) Barcelona Spain Mental Health Prevention and Early Attention Team for Patients at Risk for Psychosis (EAPPP) Catalan Health Institute (Institut Catalá de la Salut) Barcelona Spain Primary Care Catalan Health Institute (Institut Catalá de la Salut) Barcelona Spain

Background: Despite the prevalence of “professsional exhaustion syndrome” or “burnout”, very few intervention programs for healthcare professionals have been proposed, and even fewer have been evaluated. The Catalan Health Institute requested an intervention that would be preventive, integrated, and would differentiate between those affected by burnout and those with established psychopathologic disorders requiring specific treatment. Aims: To describe the experience and initial reflections from the first cohort of primary care physicians in the Barcelona public health system to participate in a program designed to prevent burnout. Methods: Descriptive analysis of the characteristics of this secondary prevention program: design, cost estimates, recruitment and screening, and activities (training, organization, and group techniques). Particular emphasis on the process of identifying potentially affected professionals, how they were offered the opportunity to participate, and the coordinated and confidential nature of the program. Results: Of a target population of 969 family doctors and pediatricians in public primary care services in Barcelona, 6 (0.61%) applied for full program participation. All of them, along with 2 non-medical professionals in primary care services who joined the program, met the clinical and psychometric criteria (Shirom-Melamed Burnout Measure, General Health Questionnaire, and the 16 Personality Factors Questionnaire) of the desired participant profile. Conclusions: The level of participation could suggest defects in program design or, alternatively, problems in the concept of burnout. This construct may be more useful for detecting stress attributed to occupational contexts than for facilitating participation in activities related to its prevention or treatment.

关键词： Burnout Psychopathology Preventive Programs Professional health Mental Health

Slowly Oscilating Solutions of Diferential Equations with Delays

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Communications in Mathematical Research 1999年第2期 91-96页

作者： N.Yousfi (Faculté des Sciences Ben Msik, Casablanca, Maroc) O.Arino (I.P.R.A.Faculté des Sciences pau. France)

§１．ＩｎｔｒｏｄｕｃｔｉｏｎＴｈｅｓｔｕｄｙｏｆｓｌｏｗｌｙｏｓｃｉｌａｔｉｎｇ（Ｓ．Ｏ．）ｓｏｌｕｔｉｏｎｓｏｆｄｅｌａｙｄｉｆｅｒｅｎｔｉａｌｅｑｕａｔｉｏｎｓｗａｓｉｎｉｔｉａｔｅｄｉｎｔｈｅ５０＇ｓｂｙｐｉ... 详细信息

§１．ＩｎｔｒｏｄｕｃｔｉｏｎＴｈｅｓｔｕｄｙｏｆｓｌｏｗｌｙｏｓｃｉｌａｔｉｎｇ（Ｓ．Ｏ．）ｓｏｌｕｔｉｏｎｓｏｆｄｅｌａｙｄｉｆｅｒｅｎｔｉａｌｅｑｕａｔｉｏｎｓｗａｓｉｎｉｔｉａｔｅｄｉｎｔｈｅ５０＇ｓｂｙｐｉｏｎｅｅｒｉｎｇｗｏｒｋｏｆＷｒｉ...

关键词： Delay Differential Equation Cauchy Problem Slowly Oscillating Solution

城市空间变革与社会可持续发展——关于瓦伦西亚图里亚河道公园的讨论

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中国文化产业评论 2021年第2期30卷 214-231页

作者：王莹 pau.Rausell-Köster 云南大学瓦伦西亚大学

关于可持续发展的理念,随着人类社会实践的开展不断深入,“社会可持续性”已经越来越被认同是可持续的综合性目标。城市作为人类生存的首要空间,其可持续发展直接关系到社会进步和人类福祉。立足于城市空间对人类发展的社会价值,本文分... 详细信息

关于可持续发展的理念,随着人类社会实践的开展不断深入,“社会可持续性”已经越来越被认同是可持续的综合性目标。城市作为人类生存的首要空间,其可持续发展直接关系到社会进步和人类福祉。立足于城市空间对人类发展的社会价值,本文分析西班牙瓦伦西亚市的图里亚河道公园项目,讨论空间变革与社会可持续之间的关系,为城市空间治理提供案例参考。

关键词：城市空间变革社会可持续性图里亚公园

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Automatic Detection of the Electrical Elicited Stapedius Reflex by Evaluation of Its Electromyographic Signals

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Engineering（科研） 2014年第4期6卷 169-176页

作者： Ralf Warmuth Martin Behrens Martin Behrens Rüdiger Dahl Karsten Ehrt Hans Wilhelm pau.Ralf Salomon Department of Exercise Science University of Rostock Rostock Germany Institute of Applied Microelectronics and Computer Engineering University of Rostock Rostock Germany Medical School ENT Department University of Rostock Rostock Germany

This paper provides a first preliminary description of the dependencies between the stapedius muscle’s behavior and its neuronal activation with the adjustment of cochlear implants in mind. For that, stapedial electromyography (EMG) data are compared with EMG data which were derived from the quadriceps femoris muscle. The rationale behind is, that the stapedius muscle is classified as a striated skeletal muscle as the quadriceps femoris muscle is. Thus, the stapedius should expose a behavior which is similar to that of peripheral skeletal muscles. The stapedial reactions were provoked with contralateral acoustic stimulation and ipsilateral electrical stimulation, respectively. The data from the quadriceps femoris muscle were evoked voluntarily. The correlation of the derived data and their stimuli have shown the following main key points: 1) The stapedius muscle behaves like a regular skeletal muscle;2) The stapedius muscle exhibits an extended range in which the muscle’s force is linear to the stimulation;3) On both sides of the linear regime, the stapedius muscle exhibits a sigmoidal behavior.

关键词： Stapedius Reflex Cochlear Implant Automatic Adjustment Electromyography Stapedial Reaction

“足迹”,一项创新性混凝土路面砖块型和铺设图案设计

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建筑砌块与砌块建筑 2013年第3期 24-27页

作者： pau.Casaldàliga Albisu 西班牙加泰罗尼亚理工大学 Pich-Aguilera建筑事务所加泰罗尼亚国际大学建筑学院

本文介绍一种根据人类足迹的几何形状,开发设计的一款连锁混凝土路面砖新块型、以及铺设图案。这种称之为"足迹"的路面砖,将路面砖连锁路面卓越的力学性能和各种图案组合相结合,形成一种在住宅庭院和公共广场都能使用的创新性新块型;它... 详细信息

本文介绍一种根据人类足迹的几何形状,开发设计的一款连锁混凝土路面砖新块型、以及铺设图案。这种称之为"足迹"的路面砖,将路面砖连锁路面卓越的力学性能和各种图案组合相结合,形成一种在住宅庭院和公共广场都能使用的创新性新块型;它也可以与任何其它小块型路面砖混合进行铺设。

关键词：连锁混凝土砖块型 “HueUa” 铺设组合

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