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National assessment of Canadian pandemic preparedness: Employing InFluNet to identify high-risk areas for inter-wave vaccine distribution

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Infectious Disease Modelling 2017年第3期2卷 341-352页

作者： patrick saunders-hastings Bryson Quinn Hayes Robert Smith Daniel Krewski University of Ottawa McLaughlin Centre for Population Health Risk Assessment850 Peter Morand CrescentOttawaOntarioK1G 5Z3Canada University of Ottawa School of EpidemiologyPublic Healthand Preventive MedicineFaculty of Medicine451 Smyth RoadOttawaONK1H 8M5Canada University of Ottawa Department of Mathematics585 King Edward AvenueOttawaONK1N 6N5Canada Risk Sciences International 55 Metcalfe StreetSuite 700OttawaONK1P 6L5Canada

Background:Influenza pandemics emerge at irregular and unpredictable intervals to cause substantial health,economic and social *** health-system response is vital to mitigating the consequences of future ***:We developed a mathematical model to assess the preparedness of Canadian health systems to accommodate pandemic-related increases in patient *** identify vulnerable areas,assess the potential of inter-wave vaccination to mitigate impacts and evaluate the association between demographic and health-system characteristics in order to identify predictors of pandemic ***:Modelled average attack rates were 23.7e37.2%with no intervention and 2.5 e6.4%with *** acute-care demand was 7.5e19.5%of capacity with no intervention and 0.6e2.6%with *** peak ICU demand was 39.3e101.8%with no intervention and 2.9e13.3%with *** mortality was 2258 e7944 with no intervention and 88e472 with *** of Southern Ontario were identified as most vulnerable to surges in patient *** strongest predictors of peak acute-care demand and ICU demand were acute-care bed capacity(R=0.8697;r^2=0.7564)and ICU bed capacity(R=0.8151;r^2=0.6644),*** characteristics had mild associations with predicted pandemic ***:Inter-wave vaccination provided adequate acute-care resource protection under all scenarios;ICU resource adequacy was protected under mild disease assumptions,but moderate and severe diseases caused demand to exceed expected availability in 21%and 49%of study areas,*** study informs priority vaccine distribution strategies for pandemic planning,emphasizing the need for targeted early vaccine distribution to high-risk individuals and areas.

关键词： consequences distribution Canadian

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数字黑暗时代

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新东方英语（中英文版） 2006年第11期 56-58页

作者： patrick White Michael hastings 董力源

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慎重选择更快的56K Modem——13种调制解调器产品评测

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微电脑世界 1997年第12期 109-113页

作者： Bryan hastings patrick Marshall 蒋志翔

现在就购买56Kbps Modem,这将是一件冒险的事。即使在购买时非常小心仔细,你应该明白所购买的56Kbps产品的速度并不能达到28.8Kbps Modem的两倍,传送文件的速度并不比33.6Kbps的Modem快多少;你也许还会遇到其他一些问题,比如你喜爱的Int... 详细信息

现在就购买56Kbps Modem,这将是一件冒险的事。即使在购买时非常小心仔细,你应该明白所购买的56Kbps产品的速度并不能达到28.8Kbps Modem的两倍,传送文件的速度并不比33.6Kbps的Modem快多少;你也许还会遇到其他一些问题,比如你喜爱的Internet服务提供商(ISP)可能不支持你的Modem所使用的协议(如X2或K56flex协议)。也就是说,一个使用X2协议的56Kbps Modem要拨号进入只支持K56flex协议的服务器时,一点也不会比33.6Kbps的Modem快。再者,你目前的电话线有可能不支持更高的速度。还有一件值得担心的事是,尽管销售商在Modem升级方面有着各种承诺,但在56Kbps标准最终出台时,你还是有可能得不到真正的56Kbps速度。

关键词：调制解调器产品评测 Internet网

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Introducing the Open Energy Ontology: Enhancing data interpretation and interfacing in energy systems analysis

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能源与人工智能(英文) 2021年第3期5卷 53-66页

作者： Meisam Booshehri Lukas Emele Simon Flügel Hannah Förster Johannes Frey Ulrich Frey Martin Glauer Janna hastings Christian Hofmann Carsten Hoyer-Klick Ludwig Hülk Anna Kleinau Kevin Knosala Leander Kotzur patrick Kuckertz Till Mossakowski Christoph Muschner Fabian Neuhaus Michaja Pehl Martin Robinius Vera Sehn Mirjam Stappel Institute for Applied Ecology BerlinGermany Institute for Applied Informatics(InfAI)/Leipzig University Germany Department of Energy Systems Analysis Institute of Networked Energy SystemsGerman Aerospace Center(DLR)StuttgartGermany Faculty of Computer Science Otto-von-Guericke-Universität MagdeburgGermany Reiner Lemoine Institut BerlinGermany Institute of Techno-economic Systems Analysis(IEK-3) Forschungszentrum JülichJülichGermany Institute of Energy Economics and Rational Energy Use University of StuttgartGermany Potsdam Institute for Climate Impact Research PotsdamGermany Fraunhofer Institute for Energy Economics and Energy System Technology KasselGermany

Heterogeneous data,different definitions and incompatible models are a huge problem in many domains,with no exception for the field of energy systems ***,it is hard to re-use results,compare model results or couple models at *** provide a precisely defined vocabulary to build a common and shared conceptu-alisation of the energy ***,we present the Open Energy Ontology(OEO)developed for the domain of energy systems *** the OEO provides several benefits for the ***,it enables consistent annotation of large amounts of data from various research *** example is the Open Energy Platform(OEP).Adding such annotations makes data semantically searchable,exchangeable,re-usable and ***,computational model coupling becomes much *** advantages of using an ontology such as the OEO are demonstrated with three use cases:data representation,data annotation and interface *** also describe how the ontology can be used for linked open data(LOD).

关键词： Collaborative ontology development Linked open data Metadata annotation Energy systems analysis

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Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup

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World Journal of Gastroenterology 2012年第26期18卷 3400-3408页

作者： Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco Department of Gastroenterology and Hepatology University Medical Center Utrecht3508 GA UtrechtThe Netherlands Division of Gastroenterology and Hepatology Kansas City Veterans Administration Medical CenterKansas CityMO 64128United States Department of Gastroenterology Bayside Endoscopy Center33 Staniford StreetProvidenceRI 02905United States Department of Gastroenterology Cliniques Universitaires Saint-LucUniversité Catholique de LouvainB-1200 BrusselsBelgium Department of Gastroenterology and Hepatology Dartmouth-Hitchcock Medical CenterOne Medical Center DriveLebanonNH 03756United States Department of Gastroenterology Istituto Clinico Humanitas20089 RozzanoItaly Department of Internal Medicine Division of Gastroenterology and HepatologyJohns Hopkins HospitalBaltimoreMD 21205United States Wolfson Unit for Endoscopy St.Mark's HospitalHarrow HA1 3UJUnited Kingdom Department of Internal Medicine Division of GastroenterologyBaylor University Medical CenterDallasTX 75246United States

AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial ***:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward *** performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the *** were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice ***:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was *** reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to *** risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic *** RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic *** a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically ***

关键词：诊断性结肠镜成像设备检出率检查监测 TEC 试验数据

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