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a.va.ces in Pola. Science 2016年第1期27卷 8-13页

作者： patricio a. flores m. Freddy Boehm.a.d Jenny m. Bla.ey a. Funda.ion Cientifica.y Cultura. Biociencia Santiago Chile Jose Domingo Cafias 2280 Santiago Chile 775-0132 Universida. de Sa.tia.o Santiago Chile

Gluta.a.e dehydrogena.e （GDH） ca.a.yzes the oxida.ive dea.ina.ion of gluta.a.e to a.ketogluta.a.e a.d a.m.nium.ions. Currently the determ.na.ion of a.m.nium.a.d gluta.a.e is ca.ried out using a.bovine GDH enzym., which la.ks optim.0} therm.sta.ility for long term.stora.e a. room.tem.era.ure. From.sa.ples of Deception Isla.d, a.ta.ctica. we obta.ned the therm.philic ba.teria.PID 15 belonging to the Ba.illus genera.with high GDH specific a.tivity. This new enzym. exhibited Na.＋ dependent a.tivity a.d no a.tivity wa. observed when Na.P＋ wa. used. This enzym. shows a.specific a.tivity of 4.7 ***-1 for the oxida.ive dea.ina.ion rea.tion a.d 15.4 U·m.-1 for the reduction of a.ketogluta.a.e. This enzym. ha. a. optim.m.tem.era.ure of 65℃ a.d pH of 8.5 for the oxida.ive dea.ina.ion. For the reduction of a.ketogluta.a.e, the optim.m.tem.era.ure is 60℃, with a.pH of 8.0. One of the m.st im.orta.t cha.a.teristics of this enzym. is its a.ility to reta.n m.re tha. 60% of its a.tivity when it is incuba.ed for 8 h a. 65℃. The enzym. is a.so a.le to reta.n full a.tivity when it is incuba.ed for 48 d a. 4℃ a.d over 80% of its a.tivity when it is incuba.ed a. 25℃. Cha.a.teriza.ion of its kinetics suggests tha. it prim.0}ily ca.a.yzes the form.0}ion of α-ketogluta.a.e. This enzym. ha. a. im.orta.t biologica. role in the ca.a.olism.of gluta.a.e a.d m.0} ha.e som. interesting biotechnologica. a.plica.ions ba.ed on its therm.sta.le properties.

关键词： a.ta.ctica gluta.a.e dehydrogena.e therm.phile

Role of N-form.l peptide receptor 2 in germ.na. m.0}rix hem.rrha.e:a. intrinsic review of a.hem.0}om.0}resolving pa.hwa.

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Neura. Regenera.ion Resea.ch 2024年第2期19卷 350-354页

作者： Jerry flores Jiping Ta.g Depa.tm.nt of Physiology&Pha.m.0}ology Loma Linda University School of MedicineLoma LindaCAUSA

Germ.na. m.0}rix hem.rrha.e is one of the lea.ing ca.ses of m.rbidity,m.rta.ity,a.d a.quired infa.tile hydrocepha.us in preterm.infa.ts in the United Sta.es,with little progress m.0}e in its clinica. *** clots ha.e been shown to elicit seconda.y bra.n injury a.ter germ.na. m.0}rix hem.rrha.e,by disrupting norm.0} cerebrospina. fluid circula.ion a.d a.sorption a.ter germ.na. m.0}rix hem.rrha.e ca.sing post-hem.rrha.ic hydrocepha.us *** evidence suggests tha. ra.id hem.0}om.0}resolution is necessa.y to im.rove neurologica. outcom.s a.ter hem.rrha.ic *** a.ticles ha.e dem.nstra.ed the beneficia. effects of stim.la.ing the pola.iza.ion of m.croglia.cells into the m. phenotype,a. it ha. been suggested tha. they pla. a. essentia. role in the ra.id pha.ocytosis of the blood clot a.ter hem.rrha.ic m.dels of stroke.N-form.l peptide receptor 2(FPR2),a.G-protein-coupled receptor,ha. been shown to be neuroprotective a.ter ***2 a.tiva.ion ha. been a.socia.ed with the upregula.ion of pha.ocytic m.0}ropha.e clea.a.ce,yet its m.cha.ism.ha. not been fully *** litera.ure suggests tha. FPR2 m.0} pla. a.role in the stim.la.ion of sca.enger receptor *** receptor CD36 pla.s a.vita. role in m.croglia.pha.ocytic blood clot clea.a.ce a.ter germ.na. m.0}rix ***2 ha. been shown to phosphoryla.e extra.ellula.-signa.-regula.ed kina.e 1/2(ERK1/2),which then prom.tes the tra.scription of the dua.-specificity protein phospha.a.e 1(DUSP1)*** this review,we present a. intrinsic outline of the m.0}n com.onents involved in FPR2 stim.la.ion a.d hem.0}om.0}resolution a.ter germ.na. m.0}rix hem.rrha.e.

关键词： a.xa. FPR2 Gm. hem.0}om.0}resolution hem.rrha.ic stroke m. m. m.croglia.pola.iza.ion m.croglia pha.ocytosis

Rem.dia.ion of a.ide pesticide-polluted soils by com.ined sola.iza.ion a.d ozona.ion trea.m.nt

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Pedosphere 2024年第3期34卷 641-651页

作者： Isa.el Ga.RIDO Ca.m.n m.a.TINEZ Pila. flores Pila. HELLIN Fulgencio CONTRERa. Jose FENOLL Depa.tm.nt of Susta.na.ility a.d Qua.ity Group of Fruit a.d Vegeta.le Products Instituto Murciano de Investigacion y Desarrollo Agrario y MedioambientalLa Alberca 30150(Spain)

a.riculture ha. a.close rela.ionship with na.ure,but it ca. a.so be the source of nega.ive a.d perm.0}ent environm.nta. *** use of pesticides in m.dern a.riculture is a.com.on pra.tice,but their side effects on the environm.nt ca.not be *** this study,we eva.ua.ed a.com.ina.ion of sola.iza.ion a.d ozona.ion techniques for the elim.na.ion of six a.ide pesticides(bosca.id,chlora.tra.iliprole,cyflufena.id,fluopyra.,na.ropa.ide,a.d propyza.ide)in *** experim.nts were perform.d with four different soils to a.sess the efficiency of this m.thodology a. different soil tem.era.ures a.d ozone dosa.es under la.ora.ory conditions,a.d then a.greenhouse pot experim.nt wa. conducted under controlled conditions during *** da.s a.ter the onset of the experim.nts,higher degra.a.ion percenta.es of a.ide pesticides were observed in ozonized soils tha. in other trea.ed soils,pa.ticula.ly when ozone wa. a.plied a. 10 cm.soil *** results show tha. the utiliza.ion of ozona.ion,a.ong with sola.iza.ion,represents a.va.id m.thod for degra.ing residues of the studied pesticides a.d suggest tha. this com.ined technology m.0} be a.prom.sing tool for rem.dia.ing pesticide-polluted soils.

关键词： interm.dia.e ozone pesticide degra.a.ion pesticide residue polyethylene film rem.dia.ion technique

Design,Synthesis,a.d a.plica.ions of m.soporous Cova.ent Orga.ic Fra.eworks

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CCS Chem.stry 2024年第1期6卷 57-68页

作者： Niya.i a.ora.Ca.sa.dra.flores m.linda.C.Sena.a.hna.Christina.m.Thom.son Rona.d a.Sm.0}done Depa.tm.nt of Chem.stry a.d Biochem.stry University of TexasDallasRichardsonTexas 75080

Cova.ent orga.ic fra.eworks(COFs)a.e highly ordered a.d perm.0}ently porous orga.ic polym.rs tha. ca. be cla.sified a. two-dim.nsiona. or *** tuna.le design a.d crysta.line order endow a.ra.ge of pore sizes,sha.es,functions,a.d a.plica.ions tha. differentia.e them.from.other *** COF pore sizes a.d sha.es rely on the geom.try of the m.nom.rs a.d dyna.ic cova.ent chem.stry,while the sta.king of the sheets relies on noncova.ent *** tuna.ility a.lows for post-m.difica.ion or the incorpora.ion of a.ditiona. functiona. groups for the reinforcem.nt by va.ious noncova.ent *** lim.ts of m.soporous COFs a.e still being investiga.ed,with the design rules continuing to *** we report a.com.rehensive review of m.soporous COFs,explore stra.egies for la.ge pore reinforcem.nt,highlight structura. design a.d fea.ures,elucida.e their va.ious functions a.d a.plica.ions,discuss funda.enta. cha.lenges fa.ed tha. need to be a.dressed,a.d predict future directions.

关键词： cova.ent orga.ic fra.eworks m.soporous supra.olecula. chem.stry polym.rs pore size

Diplopoda.in the world fossil record

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Zoologica. System.0}ics 2024年第3期49卷 185-245页

作者： m.chelle Álva.ez-Rodríguez Fra.cisco Riquelm. m.guel Hernández-patricio Fa.io Cupul-m.0}a.a La.ora.orio de Sistem.tica.m.lecula. Escuela de Estudios Superiores del JicareroUniversidad Autónoma del Estado de MorelosC.P.62909JojutlaMorelosMexico m.RN Centro de Investigaciones BiológicasUniversidad Autónoma del Estado de MorelosC.P.62209CuernavacaMorelosMexico Una.ília.e Centro Universita.io de la.Costa Universidad de GuadalajaraC.P.48280Puerto VallartaJaliscoMexico

We present a.com.rehensive ca.a.og with a. upda.ed da.a.a.e of the fossil record of Diplopoda.in the *** da.a.wa. collected from.descriptions a.d reports published from.1854 to the *** a.so include new records from.m.xica. a.ber(Upper Oligocene-Lower m.ocene),counting 83 unknown fossil inclusions,with the first records of the orders Polyxenida.Pla.ydesm.da.a.d Julida.a. well a. the fa.ilies Spha.riodesm.da. a.d Trichopolydesm.da. within *** to our results,Diplopoda.counts 413 records fea.uring 299 distinct ta.a.ra.ging from.the m.ddle Siluria. to the Upper Pleistocene,representing three subcla.ses,two subtercla.ses,six superorders,25 orders,15 superfa.ilies,55 fa.ilies,93 genera.a.d 161 fossil *** da.e,no fossils of the order Siphonocryptida.ha.e been *** fossil record extends over three geologica. era.:the Pa.eozoic,with 161 ta.a.including 97 species;the m.sozoic,with 53 ta.a.a.d 22 species;a.d the Cenozoic,with 85 ta.a.a.d 42 *** referred m.0}eria. shows different form. of fossil *** com.rises 123 im.ressions,99 com.ressions,26 ichnites,predom.na.tly from.Pa.eozoic a.d m.sozoic sedim.nts,a.d 165 a.ber inclusions from.la.e m.sozoic a.d Cenozoic ***,this ca.a.og a.lows us to estim.0}e the size a.d ta.onom.c com.osition of Diplopoda.in the fossil record worldwide.

关键词： m.llipedes Pa.eozoic m.sozoic Cenozoic new records ca.a.og

Effect of Senescence Reta.da.ts on the Qua.ity of Persia. Lim. Fruits

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Phyton-Interna.iona. Journa. of Experim.nta. Bota.y 2024年第8期93卷 1805-1818页

作者： Ra.a.l a.iza.flores Ra.a.l a.briz-Cerva.tes Pedro Ca.ena.Iñiguez Luis a.Gálvez-m.0}roquín m.guel a.Ca.o-Ga.cía Na.iona. Institute of Forestry Agriculture and Livestock Research(INIFAP)South Pacific Regional CenterSanto Domingo Barrio BajoVilla de EtlaOaxaca68200México Na.iona. Institute of Forestry Agriculture and Livestock Research(INIFAP)Zacatepec Research StationZacatepecMorelos62780México Na.iona. Institute of Forestry Agriculture and Livestock Research(INIFAP)Central Chiapas Research StationOcozocoautlaChis29140México Na.iona. Institute of Forestry Agriculture and Livestock Research(INIFAP)Oaxaca Central Valley Research StationSanto Domingo Barrio BajoVilla de EtlaOaxaca68200México

The objective of this study consisted of eva.ua.ing the effect of the a.plica.ion of chitosa.(Q),1-m.thylcyclopropene(1-m.P)under two controlled tem.era.ures on som. physica.,physiologica.,a.d chem.ca. pa.a.eters contributing to the qua.ity of Persia. lim. Citrus la.ifolia.*** trea.m.nts were eva.ua.ed,resulting from.the com.ina.ion of four senescence reta.da.t a.plica.ions(Q,1-m.P,1-m.P+Q,a.d without a.plica.ion)on fruits stored a. two tem.era.ures(12/20℃.Epiderm.s color(lum.nosity,chrom.0}icity,a.d hue),fruit a.pea.a.ce,respira.ion,weight loss,tota. juice content,tota. soluble solids,a.d titra.a.le a.idity were registered during the *** results indica.e tha. the 1-m.P a.d Q com.ina.ion fa.ored fruit postha.vest qua.ity conditions such a. reducing respira.ion ra.e;m.0}nta.ning fruit good a.pea.a.ce,turgidity,a.d brighter fruit chrom.0}icity;fruits trea.ed with chitosa. a.d stored a. 12℃,fa.ored tota. soluble *** the other ha.d,Va.ia.les such a. weight loss,juice content,a.idity,phenols,fla.onoids,a.tioxida.t a.tivity,a.d hue va.ues were fa.ored by a.12℃ storing tem.era.ure rega.dless of the *** genera.,the use of m.dified a.m.spheres,senescence reta.da.ts,a.d refrigera.ion a. postha.vest m.thods,ca. increa.e Persia. lim. shelf life.

关键词： Citrus la.ifolia qua.ity conserva.ion orga.ic a.terna.ives

Low-Cost a.d Biodegra.a.le Therm.electric Devices Ba.ed on va. der Wa.ls Sem.conductors on Pa.er Substra.es

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Energy & Environm.nta. m.0}eria.s 2024年第1期7卷 201-206页

作者： Gulsum.Ersu Ca.m.n m.nuera.Federico J.m.m.ea. Da.iel Va.uero Jorge Quereda.João Elia. F.S.Rodrigues Jose a.a.onso Edua.do flores Jose R.a.es Isa.el J.Ferrer a.dulla. m.a.-Enizi a.m.0} Na.a.y Sruthi Kuria.ose Joshua.O.Isla.d a.dres Ca.tella.os-Gom.z m.0}eria.s Science Fa.tory Instituto de Ciencia de Materiales de Madrid(ICMM-CSIC)Madrid E-28049Spain Na.otechnology Group USAL-NanolabUnivesidad de SalamancaSalamanca Junta de Castilla y León 37007Spain GISC Departamento de Física de MaterialesUniversidad Complutense de MadridMadrid E-28040Spain Depa.ta.ento de Física.a.lica.a Centro de Investigación y Estudios AvanzadosMérida 97310Mexico m.RE Group Departamento de Física de MaterialesUniversidad Autónoma de MadridMadrid E-28049Spain Instituto Nicolás Ca.rera Universidad Autónoma de MadridMadrid E-28049Spain Depa.tm.nt of Chem.stry College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Depa.tm.nt of Physics a.d a.tronom. University of Nevada Las VegasLas Vegas NV 89154USA

We present a.m.thod to fa.rica.e ha.dcra.ted therm.electric devices on sta.da.d office pa.er *** devices a.e ba.ed on thin film. of WS_(2),Te,a.d BP(P-type sem.conductors)a.d TiS_(3)a.d TiS_(2)(N-type sem.conductors),deposited by sim.ly rubbing powder of these m.0}eria.s a.a.nst *** therm.electric properties of these sem.conducting film. revea.ed m.0}im.m.Seebeck coefficients of(+1.32±0.27)m. K^(-1)a.d(-0.82±0.15)m. K^(-1)for WS_(2)a.d TiS_(3),***,Peltier elem.nts were fa.rica.ed by interconnecting the P-a.d N-type film. with gra.hite electrodes.a.therm.power va.ue up to 6.11 m. K^(-1)wa. obta.ned when the Peltier elem.nt were constructed with three *** findings of this work show proof-of-concept devices to illustra.e the potentia. a.plica.ion of sem.conducting va. der Wa.ls m.0}eria.s in future therm.electric power genera.ion a. well a. tem.era.ure sensing for low-cost disposa.le electronic devices.

关键词： pa.er-ba.ed electronics Seebeck effect sem.conductors therm.electrics va. der Wa.ls m.0}eria.s

Pig Reproductive a.d Respira.ory Syndrom. Virus (PRRSV) Does Not a.ta.h to Boa. Sperm.It a.fects Only the Velocity Pa.tern a.d the m.bility Pa.tern

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Journa. of Biosciences a.d m.dicines 2024年第4期12卷 216-228页

作者： Néstor m.ndez Pa.a.ios Netzi Na.dí m.ndez Pa.a.ios Felicita. Vázquez flores José a.fredo Ga.icia.Dom.nguez Edga. Gua.a.upe Beltrán Rosa. m.0}im.no m.ndez m.ndoza Fa.ulta. de m.dicina.Veterina.ia.a.d Zootecnia.Benem.#233 rita Universidad Aut&#243noma de Puebla Puebla Mexico Independent a.visor in the Porcine a.ea Puebla Mexico

The purpose of the study wa. to eva.ua.e the sperm.via.ility of sem.n infected with PRRSV vira. pa.ticles, observing the effect of the Virus on the m.tility of boa. sperm. The work wa. ca.ried out a. the Fm.Z-BUa. Genetics a.d Reproduction La.ora.ory. 5 sta.lions were used. Ea.h sa.ple conta.ned 1 × 106 sperm. the PRRS virus stra.n wa. a.CC-VR-2332 (0, 102, 104 a.d 106 copies of RNa.m. in triplica.e), it wa. observed da.ly a. the Ca.a.Ha.ilton Thorne®. Cells with m. (P a.s 1, 3, 5, 7 a.d 10 of eva.ua.ion with 201 ± 7.3, 167 ± 10.1, 165 ± 14.6, 134 ± 8.2 a.d 120 ± 8.8, respectively. The % m. between control a.d virus concentra.ions (P ≥ 0.05). The LCV on da. 1 a.d 7 PI a. 10X2 a.d 10X6 (P a.ion m.0}rix, where it is observed tha. there is a.correla.ion between VSL a.d Va., VSL a.d VCL, VCL a.d a.H, Va. with a.H. There is a.correla.ion of VSL a.d a.H, STR a.d a.H. In this study there were (P ≤ 0.01) in the VCL, in the concentra.ions (102) 162.81 ± 10.65 a.d (106) 177.12 ± 5.77 vs 193.04 ± 4.62 of control. This indica.es tha. a.tering these pa.a.eters would be rela.ed to fertility a.d the PRRS virus a.fects the LCV. Rega.ding the VSL, it wa. observed tha. the sperm.infected with viruses 102, 104 a.d 106 of 48.00 ± 3.38, 49.88 ± 1.83 a.d 50.55 ± 2.24 Vs. 56.66 ± 1.68 of control respectively, the control would ha.e grea.er possibilities of fertilizing the oocyte. In this study, it wa. found (P ≤ 0.01) in the Va. with 102 of 77.26 ± 5.16, 104 with 83.35 ± 2.41 a.d 106 with 81.29 ± 3.14 vs the control with 90.56 ± 2.07. Rega.ding the a.H there is (P a.104 with 8.70 ± .26 a.d 106 with 9.64 ± 0.23 vs control 8.50 ± 0.27. The presence of different concentra.ions of PRRSV in boa. sem.n induces cha.ges in different types of sperm.m.tility. Infection of ej

关键词： PRRSV Boa. Sperm. Velocity Pa.tern a.d m.bility Pa.tern

Vegeta.ion Response To Soil a.d m.rphologica. Properties In a. a.id Region a.luvia. Fa. La.dsca.e. Pre-a.des Of Sa. Jua.， a.gentina

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Journa. of Ea.th Science 2024年

作者： flores Da.iel Germ.n OCa.a.Ra.l Em.a.uel m.LIáN Edga.do ORTEG a.drés ESPER a.GILLIERI m.1}ía.Ya.ina.PITTa.UGa.m.1}ía.a.eja.dra CIGEOBIO (CONICET-UNSJ) a..José I.de la.Roza.y m.glioli Ga.inete de Geología.a.bienta.， INGEO， Universida. Na.iona. de Sa. Jua.， a..José I.de la.Roza.y m.glioli

The m.nte Desert is cha.a.terized by a.grea. diversity of la.dform. crea.ed with fluvia.， a.luvia. which the vegeta.ion pa.terns a.e rela.ed to. The present work ha. the following objectives: 1: determ.ne whether topogra.hica. a.tributes， surfa.e cha.a.teristics， soil properties a.d vegeta.ion pa.terns va.y between a.luvia. la.dform.， a.d 2: define whether m.rphom.tric， soil a.d surfa.e properties influence vegeta.ion pa.terns a.ong a.luvia. la.dsca.e. m.rphom.tric da.a.were obta.ned by processing a.5 m.digita. eleva.ion m.del. The covera.e of rock fra.m.nts， fine sedim.nts a.d m.lch wa. qua.tified. Observa.ions a.d descriptions of the soil profiles were restricted to the upperm.st 50 cm. Vegeta.ion properties were ca.cula.ed using a.Point Qua.ra. m.thod. The rela.ionship between va.ia.les wa. eva.ua.ed through m.ltiva.ia.e sta.istica. a.a.ysis. The m.0}n results show the presence of 45 pla.t species distributed in 19 fa.ilies， where shrubs a.e dom.na.t. The wind effect， topogra.hic wetness a.d dissection of the la.dsca.e a.e lim.ting fa.tors of diversity. The covera.e of superficia. rock fra.m.nts influence vegeta.ion covera.e through the distribution a.d a.a.la.ility of ra.nwa.er. Furtherm.re， the different soil textures revea. tha. the silt content fa.ors a. increa.e in vegeta.ion covera.e. The presence of V horizon could condition the insta.la.ion a.d developm.nt of vegeta.ion in the ea.ly sta.es of growth.

关键词：

C19m. m.RNa.520G induces SP100 a.tivira. gene tra.scription a.d inhibits m.la.in production in skin cuta.eous m.la.om.

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Genes & Disea.es 2024年第1期11卷 60-63页

作者： Goodwin G.Jinesh m.0}ia. T.Sm.0}lin Nino m.chedlidze Isha.Godwin m.0}co Na.oli Nicole Ha.kel m.0}a.i S.Pha.ke a.a.i a.Deshpa.de Xia.bo Li John H.Lockha.t Ja.en R.Ba.dwin Suehela. a.evedo-a.evedo Yifeng Ga. m.chelle a.Reiser Keira. S.m.Sm.0}ley Elsa.R.flores a.drew S.Brohl Depa.tm.nt of m.lecula. Oncology H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA m.lecula. m.dicine Progra. H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Sa.eetha.m.dica. College ChennaiTamil Nadu 602105India Tum.r Biology Depa.tm.nt H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Sa.com.0}Depa.tm.nt H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA

SP100 is a. a.tivira. protein tha. restricts the productive sta.e of hum.0} pa.illom.0}irus(HPV)a.d m.ltiple other viruses,a.d viruses in turn block sUm.-1-m.dia.ed sta.iliza.ion of SP100 a.d prom.tes its degra.a.ion(Ta.le S1).Interferon(IFN)signa.ing could still produce m.re SP100 through tra.scription to countera.t viruses.1 Viruses a.so disa.le the tra.scriptiona. up-regula.ion of SP100 to a.hieve persistent infection in hosts.

关键词： SP100 m.la.om. sta.iliza.ion