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Variations in porcine colostrum oligosaccharide composition between breeds and in association with sow maternal performance

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Journal of Animal Science and Biotechnology 2020年第3期11卷 830-840页

作者： paolo Trevisi Diana Luise Savanna Won Jaime Salcedo Micol Bertocchi Daniela Barile paolo Bosi Department of Agricultural and Food Sciences University of BolognaViale G.Fanin 4640127 BolognaItaly Department of Food Science and Technology University of California-DavisOne Shields AvenueDavisCA 95616USA

Background:Oligosaccharides(OS)are indigestible carbohydrates naturally found in *** composition of porcine colostrum OS may influence the growth and the health of the neonate and consuming optimal concentrations of OS may reduce piglet susceptibility to *** this manner,targeted supplementation of animal feed with OS is being explored as a health management tool in the livestock *** variation in OS composition between different breeds of pig and its association with the litter performance is currently *** aim of this study was to characterize the colostrum OS composition from sows of different breed and parity and correlate this data with sow maternal ***:Eighty-three colostrum samples from parities 1 to 8 were gathered from 3 different breeds of sow:44 Large White sows,27 Landrace sows and 12 Duroc *** were taken between the birth of the first and the last piglet from sows that were not pharmacologically induced to *** were purified from the samples and analysed by MALDI-ToF mass spectrometry(21 OS compositions detected).The farrowing season and the maternal data were recorded for each sow,including the number of live piglets and the litter body weight at birth,at day(d)3 and at ***:Five OS compositions,including isomers of the bifidogenic Sialyllactose,Lacto-N-Tetraose and Lacto-NHexaose series,were detected in all the *** other OS were identified in at least 50%of samples,and their abundances were affected by breed(P<0.05;6 of 12),marginally affected by season(P<0.10;3 of 12)and never by parity *** abundances of each OS component were standardized by Z-score scaling(μ=0 and SD=1),transformed by principal component analysis,and four similarity clusters were *** membership was associated with litter weight gain within 3 days(P=0.063)and at weaning(P<0.05),but not with piglet mortality within 3 ***:OS composition of colostrum may partially explain the vari

关键词： MALDI-ToF analysis Milk Nutrient composition Pig breeds Piglet survival

REALISTIC AND CORRECT MODELS OF IMPRESSED SOURCES FOR TIME-HARMONIC ELECTROMAGNETIC BOUNDARY VALUE PROBLEMS INVOLVING METAMATERIALS

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第3期4卷 97-148页

作者： paolo FERNANDES MIRCO RAFFETTO Istituto di Matematica Applicata e Tecnologie Informatiche del Consiglio Nazionale delle Ricerche Via De Marini 6 I-16149 GenoaItaly Department of Biophysical and Electronic Engineering University of Genoa Via Opera Pia 11a I-16145GenoaItaly

The aim of this work is to analyze the role of the impressed sources in determining the well or ill-posedness of time harmonic electromagnetic boundary value problems involving isotropic effective *** is shown,in particular,that,even if all interfaces are regular,the class of ill-posed problems can be very large in the presence of general square-integrable impressed ***,when a simple and realistic constraint is enforced on these sources,requiring that the support of the sources does not include any interface between a traditional medium and a metamaterial,among the problems here considered just those involving an interface between complementary materials remain *** considerations have a very significant impact also on the approximability of the solution of well-posed problems since the numerical noise can introduce small fictitious sources even where the sources to be simulated are not *** effects on finite element simulators are fully ***,we propose an algorithm that allows to obtain much better approximations of the solutions of the most critical wellposed problems.

关键词： Time-harmonic electromagnetic boundary value problems electromagnetic modeling of composite media waveguide discontinuity problems ill-posedness metamaterials electromagnetic simulators finite element methods.

Response to Commentary by Dr. Matthew J. Clarkson on

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Journal of Sport and Health Science 2024年第5期13卷 670-671页

作者： Hugo de Luca Corrêa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araújo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinésio Silva Neto Cláudio Avelino Rodrigues Santos paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitória Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA Clinical Group Home Dialysis Center and RenalClass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil g Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Dear editor:We sincerely thank Matthew *** for his insightful commentary1 on our recent publication in the Journal of Sport and Health Science.2 Clarkson's pioneering work in the development and application of blood flow restriction (BFR) exercise protocols has undeniably laid the groundwork for subsequent investigations in this field,including our own.(3-6)His commentary not only highlights the relevance and timeliness of our study but also offers valuable perspectives on refining safety considerations for intradialytic BFR exercise among hemodialysis patients.

关键词： patients application flow

Clinical management of inflammatory bowel disease in the organ recipient

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World Journal of Gastroenterology 2014年第13期20卷 3525-3533页

作者： Amedeo Indriolo paolo Ravelli Digestive Endoscopy Unit Department of GastroenterologyPapa Giovanni XXIII Hospital24127 BergamoItaly

There was estimated a higher incidence of de novo inflammatory bowel disease (IBD) after solid organ transplantation than in the general population. The onset of IBD in the organ transplant recipient population is an important clinical situation which is associated to higher morbidity and difficulty in the medical therapeutic management because of possible interaction between anti-reject therapy and IBD therapy. IBD course after liver transplantation (LT) is variable, but about one third of patients may worsen, needing an increase in medical therapy or a colectomy. Active IBD at the time of LT, discontinuation of 5-aminosalicylic acid or azathioprine at the time of LT and use of tacrolimus-based immunosuppression may be associated with an unfavorable outcome of IBD after LT. Anti-tumor necrosis factor alpha (TNFα) therapy for refractory IBD may be an effective and safe therapeutic option after LT. The little experience of the use of biological therapy in transplanted patients, with concomitant anti-rejection therapy, suggests there be a higher more careful surveillance regarding the risk of infectious diseases, autoimmune diseases, and neoplasms. An increased risk of colorectal cancer (CRC) is present also after LT in IBD patients with primary sclerosing cholangitis (PSC). An annual program of endoscopic surveillance with serial biopsies for CRC is recommended. A prophylactic colectomy in selected IBD/PSC patients with CRC risk factors could be a good management strategy in the CRC prevention, but it is used infrequently in the majority of LT centers. About 30% of patients develop multiple IBD recurrence and 20% of patients require a colectomy after renal transplantation. Like in the liver transplantation, anti-TNFα therapy could be an effective treatment in IBD patients with conventional refractory therapy after renal or heart transplantation. A large number of patients are needed to confirm the preliminary observations. Regarding the higher clinica

关键词： Inflammatory bowel disease, Ulcerative colitis, Crohn’ s disease, Primary sclerosing cholangitis, Liver transplantation, Heart transplantation, Renal transplantation, Anti-tumor necrosis factor alpha therapy

全球生活用纸设备供需变化:可持续性、能源节约和数字化

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生活用纸 2024年第5期24卷 43-51页

作者： Jenny Lahti Samuelsson paolo Raffaelli Shinji Goda Marcelo Marlon Silveira dos Santos 彭伟东 Roy Vincent Valter Canelli 维美德生活用纸拓斯克川之江设计部 Hergen工程应用技术部门宝索机械制造有限公司安德里茨北美生活用纸亚赛利纸业

在当前的经济环境下,设备高度灵活性已成为全球产业供应链应对生产时的特点,主要体现为对生产环节的持续监测和先进诊断技术、高效的数据储存、智能自动化、热电联产,以及减碳采购等措施。Tissue World杂志对全球领先的卫生纸机供应商... 详细信息

在当前的经济环境下,设备高度灵活性已成为全球产业供应链应对生产时的特点,主要体现为对生产环节的持续监测和先进诊断技术、高效的数据储存、智能自动化、热电联产,以及减碳采购等措施。Tissue World杂志对全球领先的卫生纸机供应商进行了专访,请他们分别就全球生活用纸市场的可持续能源利用及智能化设备生产技术等话题发表独到见解。

关键词：供需变化可持续能源智能自动化智能化设备数据储存生活用纸卫生纸机能源节约

Quantum cellular automata and free quantum field theory

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Frontiers of physics 2017年第1期12卷 65-75页

作者： Giacomo Mauro D'Ariano paolo Perinottit QUIT Group Dipartimento di Fisica via Bassi 6 1-27100 Pavia Italy

In a series of recent papers [1-4] it has been shown how free quantum field theory can be derived without using mechanical primitives （including space-time, special relativity, quantization rules, etc.）, but only considering the easiest quantum algorithm encompassing a countable set of quantum systems whose network of interactions satisfies the simple principles of unitarity, homogeneity, locality, and isotropy. This has opened the route to extending the axiomatic information-theoretic derivation of the quantum theory of abstract systems [5, 6] to include quantum field theory. The inherent discrete nature of the informational axiomatization leads to an extension of quantum field theory to a quantum cellular automata theory, where the usual field theory is recovered in a regime where the discrete structure of the automata cannot be probed. A simple heuristic argument sets the scale of discreteness to the Planck scale, and the customary physical regime where discreteness is not visible is the relativistic one of small waveveetors. In this paper we provide a thorough derivation from principles that in the most general case the graph of the quantum cellular automaton is the Cayley graph of a finitely presented group, and showing how for the case corresponding to Euclidean emergent space （where the group resorts to an Abelian one） the automata leads to Weyl, Dirac and Maxwell field dynamics in the relativistic limit. We conclude with some perspectives towards the more general scenario of non-linear automata for interacting quantum field theory.

关键词： quantum automata quantum walks quantum fields axiomatics Planck scale

Virtual earth cloud: a multi-cloud framework for enabling geosciences digital ecosystems

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International Journal of Digital Earth 2023年第1期16卷 43-65页

作者： Mattia Santoro paolo Mazzetti Stefano Nativi National Research Council of Italy Institute of Atmospheric Pollution Research-Unit of FlorenceRomaItaly Joint Research Centre of the European Commission B6 UnitIspraltaly

Humankind is facing unprecedented global environmental and social challenges in terms of food,water and energy security,resilience to natural hazards,*** address these challenges,international organizations have defined a list of policy actions to be achieved in a relatively short and medium-term *** development and use of knowledge platforms is key in helping the decision-making process to take significant decisions(providing the best available knowledge)and avoid potentially negative impacts on society and the *** knowledge platforms must build on the recent and next coming digital technologies that have transformed society–including the science and engineering *** Earth Data(BED)science aims to provide the methodologies and instruments to generate knowledge from numerous,complex,and diverse data *** science requires the development of Geoscience Digital Ecosystems(GEDs),which bank on the combined use of fundamental technology units(*** data,learning-driven artificial intelligence,and network-based computing platform)to enable the development of more detailed knowledge to observe and test planet Earth as a *** manuscript contributes to the BED science research domain,by presenting the Virtual Earth Cloud:a multi-cloud framework to support GDE implementation and generate knowledge on environmental and social sustainability.

关键词： Earth observation geosciences digital ecosystem virtual cloud big earth data multi-cloud interoperability science

Responses of Grafted Watermelon onto Cucurbita pepo Tiana F1 Hybrid to Boron Nutritional Disorders

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Horticultural Plant Journal 2019年第5期5卷 213-220页

作者： Shirani Bidabadi Siamak Sabbatini paolo Department of Horticulture College of AgricultureIsfahan University of TechnologyIsfahan84156-83111Iran Department of Horticulture Michigan State UniversityEast LansingMI48824USA

Sensitivity to boron stress in growing media during the early seedlings stage could severely inhibit watermelon growth and development. The aim of this study was to test if watermelon(Citrullus lanatus cv. Mahbubi) performance can be improved under different boron concentrations(0, 46.31 and 935.11 μmol·L-1 H3BO3) by grafting watermelon plants onto Cucurbita pepo Tiana F1 hybrid rootstock. Shoot dry weight of grafted watermelon was significantly higher than those of non-grafted plants under boron stress conditions(0 and 935.11 μmol·L-1). Boron concentration of the aerial organs of the grafted plants was higher than in the non-grafted ones when treated with 0 μmol·L-1 H3BO3. However, with the application of boron(935.11 μmol·L-1 H3BO3), the aerial organs of grafted plants accumulated lower boron than non-grafted ones. The Cucurbita pepo rootstock also improved the absorption of several other nutrients and leaf chlorophyll content and the Fv/Fmratio was also increased at high boron root concentration. Higher activities of several antioxidant enzymes such as catalase(CAT), superoxide dismutase(SOD) and peroxidase(POX) in grafted watermelons were associated with a significant reduction in H2O2 and malondialdehyde(MDA) generation when compared with those of non-grafted plants under boron stress conditions(0 and 935.11 μmol·L-1 H3BO3). Grafted plants reported improved growth, nutrient uptake and several other physiological parameters when compared to non-grafted watermelon plants under boron stress conditions.

关键词： Citrullus lanatus Cucurbita pepo lipid peroxidation oxidative stress rootstock

Thyroid hormones and thyroid hormone receptors: Effects of thyromimetics on reverse cholesterol transport

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World Journal of Gastroenterology 2010年第47期16卷 5958-5964页

作者： Matteo Pedrelli Camilla Pramfalk paolo Parini Division of Clinical Chemistry Department of Laboratory Medicine Molecular Nutrition Unit Biosciences and Nutrition Karolinska Institutet at Karolinska University Hospital Huddinge

Reverse cholesterol transport (RCT) is a complex process which transfers cholesterol from peripheral cells to the liver for subsequent elimination from the body via feces. Thyroid hormones (THs) affect growth, develop- ment, and metabolism in almost all tissues. THs exert their actions by binding to thyroid hormone receptors (TRs). There are two major subtypes of TRs, TRα and TRβ, and several isoforms (e.g. TRα1, TRα2, TRβ1, and TRβ2). Activation of TRα1 affects heart rate, whereas activation of TRβ1 has positive effects on lipid and lipoprotein metabolism. Consequently, particular interest has been focused on the development of thyromimetic compounds targeting TRβ1, not only because of their ability to lower plasma cholesterol but also due their ability to stimulate RCT, at least in pre-clinical models. In this review we focus on THs, TRs, and on the effects of TRβ1-modulating thyromimetics on RCT in various animal models and in humans.

关键词： Cardiovascular disease Cholesterol Lipoprotein metabolism Reverse cholesterol transport Thyroid hormones Thyroid hormone receptors