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The potential role of essential oils in boosting immunity and easing cOVID-19 symptoms

clinical Traditional Medicine and Pharmacology 2024年第2期5卷 54-62页

作者： Vivek P chavda pankti c.balar Gargi Jogi Swati Marwadi Aayushi Patel Avani Doshi Jinal Ajabiya Lalitkumar Vora Department of Pharmaceutics and Pharmaceutical Technology L.M.College of PharmacyAhmedabad 380009GujaratIndia Department of Biotechnology Savitribai Phule University of Pune411041MaharashtraIndia Pharmacy Section Long Island UniversityUniversity PlazaBrooklynNY 11201United States Department of Pharmaceutical chemistry K B Raval College of PharmacyGandhinagar 382423India Department of Pharmaceutics Analysis National Institute of Pharmaceutical Education and Research(NIPER)Ahmedabad 380009GujaratIndia School of Pharmacy Queen’s University Belfast97 Lisburn RoadBT97BLUK

Background:Several trials have been conducted since the beginning of the cOVID-19 pandemic to establish possible clinical treatments for the infected ***,many these approaches have failed to demonstrate positive results in human clinical *** the middle of this investigation,essential oils attracted interest due to their numerous benefits and possible role in management of *** oils have virucidal effects at nontoxic quantities due to their tiny molecular size,high lipophilicity,and quick commencement of ***,the pulmonary exhalation,lower respiratory stimulus,and deep lung transport properties of essential oils increase their potential medicinal ***:The present review aimd to evaluate the potential efficacy of essential oil in management of ***:Following the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)guidelines,studies published in English up to January 2024 were searched in the PubMed,Scifinder,and Scopus database,using relevant keywords,such as“Essential oil and cOVID-19”,“Essential Oil and Viral Infection”,*** non-English articles,abstracts,conference papers,book chapters,and reviews were ***:A total of 108 potentially relevant articles were included for full-text review,with the emphasis is on scrutinizing the probable antiviral action of essential oils to inhibit the replication of *** tried to provide an opinion based on different studies performed using the same concept in different corners of the ***:Various essential oils hold a great potential to work as an adjuvant therapy in management and prevention of cOVID-19.

关键词： cOVID-19 SARS-coV-2 Sunlight UV radiation Essential oil

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Nature meets technology:Harnessing nanotechnology to unleash the power of phytochemicals

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clinical Traditional Medicine and Pharmacology 2024年第3期5卷 111-124页

作者： Divya Teli Riyansi Satasia Vishwa Patel Ruchi Nair Rudri Khatri Dhvani Gala pankti c.balar Kishan Patel Anu Sharma Palak Vadodariya Vivek P.chavda Department of Pharmaceutical chemistry L.M.college of pharmacyAhmedabadGujarat380009India Department of chemistry School of ScienceGujarat UniversityAhmedabadGujarat380009India Pharmacy section L.M.college of pharmacyAhmedabadGujarat380009India Department of chemistry University at BuffaloBuffaloNY 14260United States of America Department Pharmaceutical Sciences University of MassachusettsBostonMA 02125United States of America Faculty of Pharmacy Marwadi UniversityRajkotGujarat360006India Department of Pharmaceuticals and Pharmaceutical Technology L.M.college of pharmacyAhmedabadGujarat380009India

Background:Phytochemicals encompass a diverse array of bioactive substances originating from plants,exhibit-ing a broad spectrum of possible health-promoting ***,the clinical uses of these compounds are restricted due to their limited solubility,stability,bioavailability,and target ***-based delivery methods present a viable approach to address these problems and enhance the properties and biological activity of *** have the potential to augment the solubility,bioavailability,and pharmacokinetics of phytochemicals by means of several *** potential approach to enhance the surface area and solubility of phytochemicals is by lowering their particle *** process of adsorption of surfactants onto phytochemical particles can lead to the formation of micelles,which exhibit solubility in ***-mulations have the potential to enhance the uptake of phytochemicals across many biological barriers,including the intestinal ***:To study the potential of nanoformulation in enhancing the therapeutic action of phytochemicals Method:Systemic review was performed while considering some aspects of PRISM ***:The nanoparticles have a great potential in delivering the phytochemicals and could of great help in the management of various ***,exhaustive research and clinical trials are yet demanded to provide the evidential proof for the ***:In conclusion,the utilisation of ligand-functionalized nanoparticles enables the precise targeting of phytochemicals to particular cells or *** field of nanotechnology has significant promise in transform-ing the advancement and administration of phytochemicals for medicinal and preventative *** utilisation of nanotechnology holds promise in addressing the obstacles related to the physicochemical charac-teristics of phytochemicals,hence enabling the development of enhanced and precise delivery

关键词： Phytochemicals Nanotechnology Bioactivity Enhancement

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Phytochemical Loaded Nanovehicles of Biopolymer for Breast cancer:A Systemic Review

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clinical complementary Medicine and Pharmacology 2023年第4期3卷 60-78页

作者： Vivek P.chavda Suneetha Vuppu Rajashri Bezbaruah Lakshmi Vineela Nalla Siva Nageswara Rao Gajula pankti c.balar Toshika Mishra Nikita Sharma Sathvika Kamaraj Thushar Suresh Anand Sairam Bedanta Bhattacharjee Department of Pharmaceutics and Pharmaceutical Technology LM College of PharmacyAhmedabadGujarat 380009India Department of Biotechnology ScienceInnovationand Society Research lab 115Hexagon(SMV)Vellore Institute of TechnologyVelloreTamil Nadu 632014India Institute of Pharmacy Assam Medical College and HospitalDibrugarhAssam 786002India Department of Pharmaceutical Science Faculty of Science and EngineeringDibrugarh UniversityDibrugarhAssam 786004India Department of Pharmacy Koneru Lakshmaiah Education FoundationVaddeswaramAndhra PradeshIndia Department of Pharmaceutical Analysis GITAM School of PharmacyGITAM(Deemed to be University)RushikondaVisakhapatnamAndhra Pradesh 530045India Pharmacy Section LM College of PharmacyAhmedabadGujarat 380009India Departemnt of Pharmacology and Toxicology Girijananda Chowdhury Institute of Pharmaceutical Science-TezpurSonitpurAssam 784501India

Background:Breast cancer is one of the most common malignancies affecting women worldwide,emphasizing the need for effective therapeutic *** derived from plants have gained significant attention due to their potential anticancer ***:This review aims to comprehensively assess the existing literature on using phytochemical-loaded for-mulations as a therapeutic approach for breast *** analyzing the available evidence,we aim to determine the potential benefits and limitations of these formulations in terms of their anticancer activity,bioavailability,and ***:A systematic search of relevant databases was conducted to identify studies investigating phytochemical-loaded formulations in the context of breast cancer *** inclusion criteria encompassed clinical trials,preclinical studies,and in-vitro experiments that reported using phytochemicals in various formulations for breast cancer *** extraction was performed to ensure the reliability and validity of the included ***:The review highlights the diverse range of phytochemicals used in different formulations for breast cancer *** suggest that these formulations exhibit promising anticancer effects by targeting mul-tiple signaling pathways in breast cancer progression,including cell proliferation,apoptosis,angiogenesis,and ***,various delivery systems,such as nanoparticles,liposomes,and micelles,have enhanced phytochemicals’bioavailability and targeted ***:Phytochemical-loaded formulations hold immense potential as a therapeutic approach for breast cancer *** reviewed evidence indicates their ability to inhibit tumor growth,enhance chemotherapy effectiveness,and reduce adverse ***,further research is warranted to optimize the formulation strategies,investigate the long-term safety profiles,and conduct large-scale clinical trials to establish their efficacy and applicabi

关键词： Breast cancer cancer Phytochemicals Nanocerriers Nanoparticles

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Reviving Fertility:Phytochemicals as Natural Allies in the Fight against Non-genetic Male Infertility

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clinical complementary Medicine and Pharmacology 2024年第1期4卷 112-128页

作者： Vivek P.chavda Shreya S Sonak pankti c.balar Krupa Vyas Pranali Palandurkar Komal Mule Krishna Patel Vivek Hala Dixa A.Vaghela Devarshi Acharya Akta Vaishnav Jimil Gandhi Vasso Apostolopoulos Department of Pharmaceutics and Pharmaceutical Technology L M College of PharmacyAhmedabadGujarat 380008India Bharati Vidyapeeth University’s Poona college of Pharmacy ErandwaneKothrudPune 411038India Pharmacy section L M College of PharmacyAhmedabadGujarat 380008India University Department of Pharmaceutical Sciences R.T.M Nagpur 440033India Department of Pharmaceutics Khyati College of PharmacyAhmedabad 380009India IIcISST Sardar Patel UniversityVallabh Vidyanagar 388120India Institute for Health and Sport Immunology and Translational ResearchVictoria UniversityMelbourneVIC 3030Australia Immunology Program Australian Institute for Musculoskeletal ScienceMelbourneVIC 3021Australia

Background:Male infertility poses a growing challenge to the healthcare system,with its prevalence on the *** lifestyle,food,and addictions such as smoking,alcoholism,*** the *** several approaches are being investigated to prevent and treat this condition,each therapeutic approach has its *** medications continue to play a crucial role in the healthcare *** recent years,there has been a shift towards determining the efficacy of phytochemicals(or,herbal drugs)as ***:To evaluate the effect of various herbs,plant,metabolites,or a part of plant in management of non-genetic male ***:The male infertility-associated keywords were searched in PubMed,excluding those non-English writen papers.A total of 146 pertinent and closely connected records were included for full reading and inclusion in the systemic ***:The manuscript focuses on individual herbal drug components,their active ingredients,their role in improving the condition and quality of life,and decreasing the prevalence of male ***:Herbal medicinal plants show promising outcomes to treat male *** alternatives are appealing and have regained *** future holds promise for some of these herbal treatments to advance with many showing improved outcomes in males with infertility issues.

关键词： Male infertility Plant-based management Phytochemical Herbal drug Traditional chinese medicine

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