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Effects of freezing-thawing on the engineering performance of core wall soil materials of a dam in the process of construction

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Journal of Mountain Science 2020年第11期17卷 2840-2852页

作者： REN Xiu-ling yu Qi-hao ZHANG Gui-ke yuE pan LIU En-long ZHANG Zhen-yu YOU Yan-hui State key Laboratory of Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Yalong River Hydropower Development Company LtdChengdu 610065China State key Laboratory of Hydraulics and Mountain River Engineering College of Water Resources and HydropowerSichuan UniversityChengdu 610065China

The construction of water conservancy projects in cold regions experiences freezing-thawing cycles,which can greatly change the engineering properties of soil and have a significant impact on the construction of *** Hydropower Station(LHS),is a controlling station with the largest installed capacity among the 7 middle reach projects in the Yalong River,the secondary tributary of the Yangtze *** is located in a seasonally frozen soil *** on the measured data of air and ground temperature in winter in the dam core wall,the freezing-thawing variation of gravelly soil and contact clay during the filling process of the core wall are compared and analyzed,then the main impact factors of the freezing-thawing variation of soils are *** results show that under the influence of air temperature,soil freezes unidirectionally from ground surface downward and deepens gradually,and the thawing processes are different at the aspects of thawing direction and *** temperature and physical properties of soil including soil type,moisture content and dry density affect the freezingthawing processes of *** the impact of engineering construction is more remarkable than natural *** engineering construction affects soil temperature and freezing-thawing process by controlling the initial temperature of soil,the speed and duration of the technological conversion of paving,compaction,and the length of placed duration at *** to the long placed duration of soil with the slow construction method,the initial temperature of soil gradually reduces,the heat transfer process inside soil is *** the internal heat of soil releases,the decreasing rate of ground temperature of soil at different depths is fast and the frozen depth *** due to the short placed duration of soil with the rapid construction process,the initial temperature of soil is high,high internal heat of soil is supplied every day,and the heat transfer process in

关键词： Lianghekou Hydropower Station(LHS) Gravelly soil Contact clay Freezing-thawing variation Impact factors

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Altered hACE2 binding affinity and S1/S2 cleavage efficiency of SARS-CoV-2 spike protein mutants affect viral cell entry

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Virologica Sinica 2023年第4期38卷 595-605页

作者： ke Wang yu pan Dianbing Wang Ye yuan Min Li yuanyuan Chen Lijun Bi Xian-En Zhang National key Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing100101China Faculty of Synthetic Biology Shenzhen Institute of Advanced TechnologyShenzhen518055China University of Chinese Academy of Sciences Beijing100101China

SARS-CoV-2 variants are constantly emerging,hampering public health measures in controlling the number of *** it is well established that mutations in spike proteins observed for the different variants directly affect virus entry into host cells,there remains a need for further expansion of systematic and multifaceted ***,we comprehensively studied the effect of spike protein mutations on spike expression and proteolytic activation,binding affinity,viral entry efficiency and host cell tropism of eight variants of concern(VOC)and variants of interest(VOI).We found that both the full-length spike and its receptor-binding domain(RBD)of Omicron bind to hACE2 with an affinity similar to that of the *** addition,Alpha,Beta,Delta and Lambda pseudoviruses gained significantly enhanced cell entry ability compared to the wild-type,while the Omicron pseudoviruses showed a slightly increased cell entry,suggesting the vastly increased rate of transmission observed for Omicron variant is not associated with its affinity to *** also found that the spikes of Omicron and Mu showed lower S1/S2 cleavage efficiency and inefficiently utilized TMPRSS2 to enter host cells than others,suggesting that they prefer the endocytosis pathway to enter host ***,all variants'pseudoviruses we tested gained the ability to enter the animal ACE2-expressing *** the infection potential of rats and mice showed significantly increased,strongly suggesting that rodents possibly become a reservoir for viral *** insights gained from this study provide valuable guidance for a targeted approach to epidemic control,and contribute to a better understanding of SARS-CoV-2 evolution.

关键词： SARS-CoV-2 Variants of Concern(VOC) Omicron Binding affinity Viral entry Host-tropism

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Buckling of composite cylindrical shells with ovality and thickness variation subjected to hydrostatic pressure

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Defence Technology（防务技术） 2022年第5期18卷 862-875页

作者： Zhun Li ke-chun Shen Xin-hu Zhang Guang pan School of Marine Science and Technology Northwestern Polytechnical UniversityXi'an710072China key Laboratory for Unmanned Underwater Vehicle Northwestern Polytechnical UniversityXi'an710072China Structural Ceramics and Composites Engineering Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai200050China

The initial geometric imperfection is one of the primary factors affecting the buckling behaviors of composite cylindrical shells under hydrostatic *** this study,ovality and thickness variations as two representative types of the geometric imperfections are *** measuring the geometric imperfections,a typical carbon fiber reinforced polymers(CFRP)cylindrical shell is tested to obtain the buckling *** buckling behaviors of the shell sample are analyzed in combination with the strain *** using the nonlinear numerical analysis,the buckling shapes of the CFRP cylinder shells with different combinations of ovality and thickness variation are firstly *** rules of influence of such imperfections on the buckling pressure are then obtained by nonlinear regression ***,an empirical formula is proposed to predict the buckling pressure of the composite cylinder shells,and the calculated results from the formula are in good agreement with the numerical results.

关键词： Composite Cylindrical shell Buckling Hydrostatic pressure Imperfections

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Performance of Cooperative Spatial Modulation with AF Protocol in Wireless Relay Network

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Chinese Journal of Electronics 2019年第1期28卷 143-151页

作者： yu Xiangbin pan Qing WANG Cheng College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics National Mobile Communications Research Laboratory Southeast University

By combing Spatial modulation(SM) with the Amplify-and-forward(AF) cooperative communication, a cooperative SM scheme with AF(AF-SM) protocol is presented, and the corresponding Bit error rate(BER)performance is investigated. Based on the performance analysis, the error probability of antenna index estimation(Pa) and the error probability of symbol estimation(Pd),which constitutes the overall average BER, are derived,respectively. As a result, tightly approximate closedform expressions of Paand Pdare attained, *** these expressions, the closed-form overall average BER is achieved. During the analysis, the computational complexity of AF-SM detector is also provided in terms of the complex addition and multiplication ***, the asymptotic BER at high SNR and the corresponding diversity gain are further derived, and the resultant diversity gain of Nr+ 1 is obtained for the system with Nrreceive antennas. Simulation results show that our theoretical analysis is valid, and provides good performance evaluation method for cooperative SM system. Moreover, the BER performance can be effectively improved as Nrincreases due to higher diversity gain.

关键词： Spatial modulation(SM) Cooperative communication Amplify and forward protocol Diversity gain Average bit error rate

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Impact of window and air-conditioner operation behaviour on cooling load in high-rise residential buildings

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Building Simulation 2022年第11期15卷 1955-1975页

作者： Cong yu Jia Du Wei pan Department of Civil Engineering The University of Hong KongPokfulamHong KongChina

Space cooling is an important building energy end-use that was found in recent years to be significantly impacted by occupant ***,the majority of previous studies ignored the interplay between the operation of windows and air conditioners(ACs)on cooling load,particularly in building energy *** addition,studies on the analysis of cooling load characteristics regarding high-rise buildings are *** vertical effect of high-rise buildings on cooling load remains *** study thus aims to examine how window and AC operation behaviours impact the cooling load of high-rise buildings in an urban context demonstrated by a real-life typical 40-floor residential building in Hong *** study investigates window and AC operation behaviours jointly and examines the vertical effect on cooling load by using agent-based building energy modelling(BEM)techniques and initiating stochastic and diverse behaviour modes.A carefully designed questionnaire survey was conducted to help build behaviour modes and validate energy *** building energy models were established integrating meteorological parameters generated by the computational fluid dynamics(CFD)programme for ten typical floors and nine combinations of window and AC behaviour *** results show that comfort-based AC modes and schedule-based window modes yielded the lowest cooling *** the combined effect of AC and window uses,the maximum difference in cooling loads could be 26.8%.Behaviour modes and building height induce up to 32.4%differences in cooling ***,a deviation between the behaviour modes and height on the cooling load was *** findings will help develop a thorough energy model inferring occupants’window and AC behaviour modes along with the building height in high-rise residential *** findings indicate that the interaction impact of window and AC behaviour modes and height should be jointly considered in future high-rise buildin

关键词： occupant behaviour air conditioning natural ventilation high-rise residential building building energy use

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A correlative denoising autoencoder to model social influence for top-N recommender system

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Frontiers of Computer Science 2020年第3期14卷 31-43页

作者： Yiteng pan Fazhi HE Haiping yu School of Computer Science Wuhan UniversityWuhan 430072China

In recent years,there are numerous works been proposed to leverage the techniques of deep learning to improve social-aware recommendation *** most cases,it requires a larger number of data to train a robust deep learning model,which contains a lot of parameters to fit training ***,both data of user ratings and social networks are facing critical sparse problem,which makes it not easy to train a robust deep neural network *** this problem,we propose a novel correlative denoising autoencoder(CoDAE)method by taking correlations between users with multiple roles into account to learn robust representations from sparse inputs of ratings and social networks for *** develop the CoDAE model by utilizing three separated autoencoders to learn user features with roles of rater,truster and trustee,***,on account of that each input unit of user vectors with roles of truster and trustee is corresponding to a particular user,we propose to utilize shared parameters to learn common information of the units that corresponding to same ***,we propose a related regularization term to learn correlations between user features that learnt by the three subnetworks of CoDAE *** further conduct a series of experiments to evaluate the proposed method on two public datasets for Top-N recommendation *** experimental results demonstrate that the proposed model outperforms state-of-the-art algorithms on rank-sensitive metrics of MAP and NDCG.

关键词： social network recommender system denoising autoencoder neural network

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Predictive Event-Triggered Control for Disturbanced Wireless Networked Control Systems

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Journal of Systems Science & Complexity 2021年第3期34卷 1028-1043页

作者： ZHAO yunbo pan Xiaokang yu Shiming College of Information Engineering Zhejiang University of TechnologyHangzhou 310023China

The control and scheduling for wireless networked control system with packet dropout and disturbance are investigated.A prediction based event triggered control is proposed to reduce data transmissions while preserving the robustness against external ***,a trigger threshold is especially designed to maintain the difference of the estimated and actual states below a proper boundary when system suffers from packet *** a predictive controller is designed to compensate for packet dropouts by utilizing the packet-based control *** sufficient conditions to ensure the closed-loop system being uniformly ultimately bounded are derived,with consequently the controller gain *** examples illustrate the effectiveness of the proposed approach.

关键词： Event-trigger packet-based control wireless networked control systems

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Efficient capture of iodine and methyl iodide using all-silica EMM-17 zeolite

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Nano Research 2023年第5期16卷 6308-6315页

作者： Tingting pan Xinglong Dong yu Han Advanced Membranes and Porous Materials(AMPM)Center Physical Sciences and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Saudi Arabia

Hydrophobic zeolites have been identified as suitable adsorbents for capturing radioactive iodine species from nuclear-powerplant off-gas because of their high stability and strong water ***,only the most common zeolites have been investigated for the capture of molecular iodine to ***,we demonstrate that the composition and pore structure of zeolites considerably affect their iodine adsorption performance.A novel all-silica ExxonMobil material-17(EMM-17)zeolite having a unique three-dimensional 10(12)×10(12)×11-ring channel system exhibits a high adsorption capacity for iodine and methyl iodide in the presence of ***-17 outperforms previously reported zeolites in terms of gravimetric and volumetric adsorption capacity in dynamic adsorption *** excellent iodine/methyl iodide capture properties are attributed to the combination of optimal pore size,high pore volume,strong hydrophobicity,suitable particle *** study provides useful insights for designing efficient adsorbents for iodine capture.

关键词： ExxonMobil material-17(EMM-17)zeolite iodine capture methyl iodide adsorption

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State-sensitive convolutional sparse coding for potential biomarker identification in brain signals

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Science China(Information Sciences) 2024年第5期67卷 270-286页

作者： Puli WANG yu QI Gang pan College of Computer Science and Technology Zhejiang University State key Laboratory of Brain-Machine Intelligence Zhejiang University MOE Frontier Science Center for Brain Science and Brain-machine Integration Zhejiang University Affiliated Mental Health Center & Hangzhou Seventh People's Hospital Zhejiang University School of Medicine

The identification of prototypical waveforms, such as sleep spindles and epileptic spikes, is crucial for the diagnosis of neurological disorders. These prototypical waveforms are usually recurrently presented in certain brain states, serving as potential biomarkers for clinical evaluations. Convolutional sparse coding(CSC) approaches have demonstrated strength in identifying recurrent patterns in time-series. However,existing CSC approaches do not explicitly explore state-specific patterns, making it difficult to identify state-related biomarkers. To address this problem, we propose state-sensitive CSC to learn state-specific prototypical waveforms. Specifically, we model signals of a certain state with specific waveforms that only appear frequently in this state and background waveforms that are independent of states. Based on this,state-sensitive CSC separates state-specific waveforms from background ones explicitly by incorporating incoherence constraints into optimizations. Experiments with epilepsy brain signals demonstrate that our approach can effectively identify prototypical waveforms in pre-ictal states, providing potential biomarkers for seizure prediction. Our approach provides a promising tool for automatic biomarker candidate identification.

关键词： convolutional sparse coding prototypical waveforms state-specific dictionary biomarker identification neural signal processing

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Niclosamide,an old antihelminthic agent,demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells

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Chinese Journal of Cancer 2012年第4期31卷 178-184页

作者： Jing-Xuan pan ke Ding Cheng-Yan Wang Department of Pathophysiology Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510089P.R.China key Laboratory of Regenerative Biology and Institute of Chemical Biology Guangzhou Institute of Biomedicine and HealthChinese Academy of SciencesGuangzhou Science ParkGuangzhouGuangdong 510089.P.R.China.

Niclosamide,an oral antihelminthic drug,has been used to treat tapeworm infection for about 50 *** is also used as a molluscicide for water treatment in schistosomiasis control ***,several groups have independently discovered that niclosamide is also active against cancer cells,but its precise mechanism of antitumor action is not fully *** supports that niclosamide targets multiple signaling pathways (NF-κB,Wnt/β-catenin,Notch,ROS,mTORC1,and Stat3),most of which are closely involved with cancer stem *** exciting advances in elucidating the antitumor activity and the molecular targets of this drug will be discussed.A method for synthesizing a phosphate pro-drug of niclosamide is *** its potential antitumor activity,clinical trials for niclosamide and its derivatives are warranted for cancer treatment.

关键词：抗肿瘤活性氯硝柳胺信号转导途径干细胞癌症驱虫剂显示杀软体动物剂

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