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phytophthora Effectors Modulate Genome-wide Alternative Splicing of Host mRNAs to Reprogram plant Immunity

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Molecular plant 2020年第10期13卷 1470-1484页

作者： Jie Huang Xinyu Lu Hongwei Wu Yuchen Xie Qian peng Lianfeng Gu Juyou Wu Yuanchao Wang Anireddy SNreddy Suomeng Dong Department of plant pathology Nanjing Agricultural UniversityNanjing 210095China Basic Forestry and proteomics Research Center College of ForestryFujian Agriculture and Forestry UniversityFuzhou 350002China State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjing 210095China Colorado State University Program in Cell and Molecular BiologyFort CollinsCO 80523USA Key Laboratory of Integrated Management of Crop Diseases and pests(Ministry of Education) Nanjing 210095China The Key Laboratory of plant Immunity Nanjing Agricultural UniversityNanjing 210095China

Alternative splicing(AS)of pre-mRNAs increases transcriptome and proteome diversity,regulates gene expression through multiple mechanisms,and plays important roles in plant development and stress ***,the prevalence of genome-wide plant AS changes during infection and the mechanisms by which pathogens modulate AS remain poorly ***,we examined the global AS changes in tomato leaves infected with phytophthora infestans,the infamous Irish famine *** show that more than 2000 genes exhibiting significant changes in AS are not differentially expressed,indicating that AS is a distinct layer of transcriptome reprogramming during plant-pathogen ***,our results show that *** subverts host immunity by repressing the AS of positive regulators of plant immunity and promoting the AS of susceptibility *** study the underlying mechanism,we established a luminescence-based AS reporter system in Nicotiana benthamiana to screen pathogen effectors modulating plant *** identified nine splicing regulatory effectors(SREs)from 87 *** *** studies revealed that SRE3 physically binds U1-70K to manipulate the plant AS machinery and subsequently modulates AS-mediated plant *** study not only unveils genome-wide plant AS reprogramming during infection but also establishes a novel AS screening tool to identify SREs from a wide range of plant pathogens,providing opportunities to understand the splicing regulatory mechanisms through which pathogens subvert plant immunity.

关键词： late blight phytophthora infestans alternative splicing splicing regulatory effectors plant immunity tomato

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掺杂钠盐聚氯乙烯膜的结构及介电性能研究

化学推进剂与高分子材料 2006年第2期4卷 54-57页

作者：朱泉峣靳艾平 Ch.V.Subba reddy 陈文武汉理工大学材料科学与工程学院湖北武汉430070

选用聚氯乙烯(pVC)为基体材料,加入不同含量的NaClO4,采用溶液浇注法制备不同组成的聚合物电解质薄膜,采用XRD和FT-IR对其结构进行了分析,运用电化学阻抗谱(EIS)对其介电性能进行了测试。实验结果表明:高氯酸钠(NaClO4)在pVC基体材料中... 详细信息

选用聚氯乙烯(pVC)为基体材料,加入不同含量的NaClO4,采用溶液浇注法制备不同组成的聚合物电解质薄膜,采用XRD和FT-IR对其结构进行了分析,运用电化学阻抗谱(EIS)对其介电性能进行了测试。实验结果表明:高氯酸钠(NaClO4)在pVC基体材料中以复合状态存在,Na+离子与pVC中的Cl发生络合作用。复合体系的介电常数随NaClO4含量增加而降低,并且在较低的频率和较高的温度时下降很快,而在较高的频率和较低的温度时下降缓慢。在1kHz频率时,随温度升高,体系的损耗角正切逐渐增大。

关键词：聚合物电解质聚氯乙烯高氯酸钠介电性能

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Soybean seed protein, oil, and fatty acids are altered by S and S + N fertilizers under irrigated or non-irrigated environments

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Agricultural Sciences 2011年第4期2卷 465-476页

作者： Nacer Bellaloui M. Wayne Ebelhar Anne M. Gillen Daniel K. Fisher Hamed K. Abbas Alemu Mengistu Krishna N. reddy Robert L. paris 不详

Information on the effect of sulfur (S) or sulfur+nitrogen (S + N) on soybean seed composition is scarce. Thus, the objective of this study was to investigate the effects of S, and S + N fertilizers on soybean [(Glycine max (L.) Merr.)] seed composition in the Early Soybean production System (ESpS) under irrigated (I) and nonirrigated (NI) environments. Two separate field experiments were conducted from 2005 to 2007. One experiment was irrigated, and the second experiment was nonirrigated. Under I condition, S at a rate of 44.8 kg/ha alone or with N at 112 kg/ha resulted in a consistent increase in seed protein and oleic acid concentrations, and a decrease in oil and linolenic acid concentrations compared with the control (C). For example, in 2006 and compared with the C, application of S + N increased the percentage up to 11.4% and 48.5% for protein and oleic acid, respectively. However, oil concentration decreased by 3%. protein and oleic acid increase were accompanied by a higher percentage of leaf and seed N and S. Under NI conditions, seed protein and oleic acid concentrations were significantly higher in C than in any S or S + N treatments, but the oil and linolenic acid concentrations were significantly lower. The results indicate that specific rate of S alone or S + N combined can alter seed composition under irrigated or nonirrigated conditions. This knowledge may help plant breeders to develop and release cultivars to suit specific target locations to grow new value-added soybeans or select for specific seed composition traits under specific environmental stress factors such as drought.

关键词： Fatty Acids Nutrition Oil protein Seed Composition Soybean

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橄榄石组构指示始太古代的板块俯冲

矿物岩石地球化学通报 2016年第5期35卷 826-826页

作者：夏群科 Kaczmarek Mary-Alix reddy S M Nutman A p Friend C R L Bennett V C

板块构造深刻影响着地球的性质、行为和演化，但是对于板块构造开始的时间，一直没有定论。目前已经有些研究表明，始太古代（40～36亿年）甚至更早，地球上可能就有板块构造运动的发生。

关键词：板块俯冲太古代橄榄石组构板块构造构造运动地球

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Oxidative stress and Immune dysfunction in petrol filling workers

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Oxidative stress and Immune dysfunction in Petrol filling wo...

第14届国际自由基学术大会

作者： B.M. Khaja Mohinuddin Salar Nazia Uzma B. Santhosh Kumar Nusrat Aziz M.Anthony David V. Devender reddy Department of physiology Deccan College of Medical Sciences Hyderabad India-500 058

＜正＞The potential for oxidative stress to contribute to benzene toxicity is closely tied to specific benzene metabolites like hydroquinone （HQ）. HQ may be oxidized to p-benzoquinone, which is highly reactive and can covalently bind to cellular macromolecules or to glutathione. Alternatively, benzene metabolites may engage in redox cycling,

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急性风湿热伴严重房室传导阻滞

国际儿科学杂志 1990年第6期 334-334页

作者： reddy DV 王学东

在美国大陆,风湿热的发病率已经下降,但在夏威夷和世界某些地区则不然,甚至于有所上升。本文报道了5例伴第二度或第三度房室传导阻滞(AVB)的急性风湿热(ARF)。方法作者调查了1980年10月至1984年9月的4年间美国瓦胡(Oahu)岛10个医院的住... 详细信息

在美国大陆,风湿热的发病率已经下降,但在夏威夷和世界某些地区则不然,甚至于有所上升。本文报道了5例伴第二度或第三度房室传导阻滞(AVB)的急性风湿热(ARF)。方法作者调查了1980年10月至1984年9月的4年间美国瓦胡(Oahu)岛10个医院的住院病例,病人年龄为4～18岁,符合修订的 JonesARF 诊断标准的共98例,其中3例伴第二度或第三度 AVB。在此调查期间前,火努鲁鲁(Honolulu)岛另有2

关键词：房室传导阻滞急性风湿热心室纤颤 AVB 心瓣膜炎

基于单分散棒状病毒的非球形颗粒复杂流体体系的构建及其流变行为研究

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基于单分散棒状病毒的非球形颗粒复杂流体体系的构建及其流变行为...

Lipid Metabolic profile Interrelationships between the Silkworm(Bombyx mori L.)and Its Host plant(Morus)Varieties

流变学进展——第十一届全国流变学学术会议

作者：张珍坤 Naveen Krishna reddy Jan Vermant Christian Clasen 南开大学高分子化学研究所 Department of Chemical Engineering University of Leuven B-3001 Leuven Belgium

自然界的复杂流体体系绝大部分由非球形颗粒构成。长期以来,理论和实验都从不同角度对这类体系的流变行为进行了详细探讨。理论上,Jeffrey对椭球体流变行为的理论计算开启了类似体系理论研究的先河,随后Brosema、Brenner等从不同角度对... 详细信息

自然界的复杂流体体系绝大部分由非球形颗粒构成。长期以来,理论和实验都从不同角度对这类体系的流变行为进行了详细探讨。理论上,Jeffrey对椭球体流变行为的理论计算开启了类似体系理论研究的先河,随后Brosema、Brenner等从不同角度对棒状颗粒构成的复杂流体进行了扩充。Batchleor则对这类体系的轴向拉升流场下的流变行为进行了研究。实验上,早期主要集中在表征不同长度的棒状纤维的流变行为,在一定程度上吻合了理论的预测。过去的十几年,人们对由无机颗粒如针状的赤铁矿、棒状的二氧化硅颗粒、碟状的黏土颗粒以及生物相关的棒状体系如F-actin等构成的模型体系进行了广泛深入的实验研究。随着纳米科学的兴起,碳纳米管构成的复合材料的流变行为是近期的一个研究热点。然而,目前为止的实验模型不可避免地具有尺寸不均一性和颗粒表面物化性质的不确定性等问题,导致实验结果的不可重复性以及与理论的不可比性。在本项目中,基于棒状病毒,结合基因控制和表面化学改性,构建了一类尺寸单一、刚性和表面性质可控的非球形颗粒的复杂流体体系,并对这类体系构成的凝胶进行了详细的流变表征,建立起微观结构与宏观流变行为之间的关系。将表面接枝有高分子刷的棒状病毒分散到甘油等高黏度的牛顿流体后,采用两种不同的技术手段对该体系的轴向拉升流场下的流变行为进行了研究,并与Batchleor等人的理论研究进行了比较。

关键词：复杂流体棒状病毒流变行为

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Agricultural Science & Technology 2009年第6期10卷 128-134页

作者： Y.Srinivasa reddy Firdose Ahmad Malik S.S.Mamatha G.Venkateswaran 迈索尔大学蚕业科学系中央食品和技术研究院(CFTRI)食品微生物系印度迈索尔570020

The lipid content and composition in tender, medium and coarse leaves of 3 mulberry varieties were analyzed. Tender leaf contained more lipid than medium and coarse leaves. Fatty acid composition of lipids also varied with leaf maturity. Tender leaf contained more precursor fatty acids, medium leaf more unsaturated fatty acids and coarse leaf more saturated fatty acids. V-1 mulberry variety had more foliar lipid con- tent than S-36 and M-5. Lipid composition also varied among the 3 mulberry varieties. V-1 and S-36 leaves contained more unsaturated fatty acids and M-5 more saturated fatty acids. V instar silkworm was fed with the medium leaf of the 3 mulberry varieties, and the total lipid content and fatty acid composition of the haemolymph, fatbody and excreta were analyzed. Lauric acid （12：0）, undetectable in the haemolymph, was recovered in significant quantity in the excreta. Saturated fatty acids （16：0 and 18：0） were higher in the haemolymph of larvae fed on M-5 while unsaturated fatty acids （18：2 and 18：3） were higher in those fed on S-36 and V-1 leaves. But, the percentage levels of 18：1 and 18：2 fatty acids in the leaf and haemolymph were swapped. While the leaf of M-5 mulberry variety had 18：1 and 18：2 fatty acid components at 1.93% and 16.8%, the larvae feeding on the leaf had 18：1 and 18：2 at 21.5% and 6.95% in the haemolymph. Similar correction in the percentages of the two unsaturated fatty acids was observed in the larvae feeding on the leaves of S-36 and V-1. Saturation of co -6 double bond of linoleic acid by a reductase in the lower end of the midgut was proposed.

关键词： Mulberry leaves Bombyx moil Saturated fatty acids polyunsaturated fatty acids

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霉菌毒素问题的生物解决途径

湖南饲料 2005年第3期 25-29页

作者： G.DEVEGOWDA,T.N.K.MURTHY,B.N.reddy 农业科学大学兽医学院农业科学大学兽医学院农业科学大学兽医学院印度班加罗尔印度班加罗尔印度班加罗尔

1霉菌毒素概况世界上已知的真菌有10000多种。幸运的是,其中大部分都是对人类有益的,它们可用来生产面包、奶酪,以及抗生素等。但是,还是有大约50多种真菌对畜禽和人类是有害的,它们可以产生毒素,统称为霉菌毒素。霉菌毒素是真菌在代谢... 详细信息

1霉菌毒素概况世界上已知的真菌有10000多种。幸运的是,其中大部分都是对人类有益的,它们可用来生产面包、奶酪,以及抗生素等。但是,还是有大约50多种真菌对畜禽和人类是有害的,它们可以产生毒素,统称为霉菌毒素。霉菌毒素是真菌在代谢饲料和饲料原料中的营养物质的过程中所产生的代谢产物。

关键词：霉菌毒素动物生产性能醋化日粮毒枝菌素霉菌毒素吸附剂葡配甘露聚糖黄曲霉毒素 EGM