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performance analysis of ASR system in hybrid DNN-HMM framework using a pWL euclidean activation function

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Frontiers of Computer Science 2021年第4期15卷 185-195页

作者： Anirban DUTTA Gudmalwar ASHISHKUMAR Ch V rama rao Department of Electronics and Communication Engineering National Institute of Technology MeghalayaShillong 793003India

Automatic Speech Recognition(ASR)is the process of mapping an acoustic speech signal into a human readable text *** systems exploit the Acoustic Component of ASR using the Gaussian Mixture Model-Hidden Markov Model(GMM-HMM)*** NeuralNetwork(DNN)opens up new possibilities to overcome the shortcomings of conventional statistical *** studies modeled the acoustic component of ASR system using DNN in the so called hybrid DNN-HMM *** the context of activation functions used to model the non-linearity in DNN,Rectified Linear Units(ReLU)and maxout units are mostly used in ASR *** paper concentrates on the acoustic component of a hybrid DNN-HMM system by proposing an efficient activation function for the DNN *** by previous works,euclidean norm activation function is proposed to model the non-linearity of the DNN *** non-linearity is shown to belong to the family of piecewise Linear(pWL)functions having distinct *** functions can capture deep hierarchical features of the *** relevance of the proposal is examined in depth both theoretically and *** performance of the developed ASR system is evaluated in terms of phone Error Rate(pER)using TIMIT *** results achieve a relative increase in performance by using the proposed function over conventional activation functions.

关键词： deep learning euclidean piecewise linear speech recognition activation function

HbA_(1)c结合神经肌电图在糖尿病周围神经病变早期诊断中的应用价值

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蛇志 2024年第2期36卷 213-216页

作者：饶丹黔西南州人民医院神经电生理科贵州兴义562400

目的研究糖化血红蛋白(HbA_(1)c)结合神经肌电图在糖尿病周围神经病变(DpN)早期诊断中的应用价值。方法选择2022年1月至2023年1月我院收治的45例糖尿病合并DpN患者作为DpN组,选择同期收治的68例非DpN糖尿病患者作为NDpN组。比较两组患者... 详细信息

目的研究糖化血红蛋白(HbA_(1)c)结合神经肌电图在糖尿病周围神经病变(DpN)早期诊断中的应用价值。方法选择2022年1月至2023年1月我院收治的45例糖尿病合并DpN患者作为DpN组,选择同期收治的68例非DpN糖尿病患者作为NDpN组。比较两组患者的HbA_(1)c及神经肌电图,分析HbA_(1)c结合神经肌电图在DpN早期诊断中的价值。结果DpN组患者的HbA_(1)c水平显著高于NDpN组,差异具有统计学意义(ppN组正中神经、腓总神经和尺神经的运动传导速度(MCV)与正中神经、腓浅神经和尺神经的感觉传导速度(SCV)均明显低于NDpN组,差异均有统计学意义(均ppN的ROC曲线下面积(AUC)为0.85,当HbA_(1)c在8.12%时,敏感度与特异度分别为89%、68%。各神经传导速度诊断DpN的AUC均>0.75,但单一指标的敏感度或特异度较低。HbA_(1)c联合各神经传导速度诊断DpN的敏感度和特异度分别为98%和94%(ppN的早期诊断中有极高的准确性和可靠性。

关键词：糖尿病周围神经病变神经肌电图糖化血红蛋白诊断价值

超微血管显像在乳腺癌早期诊断、病情判断及疗效评估中的价值

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临床医学研究与实践 2024年第9期9卷 109-112页

作者：付饶安阳市人民医院超声科河南安阳455000

目的探讨超微血管显像(SMI)在乳腺癌早期诊断、病情判断及疗效评估中的价值。方法选取我院2020年4月至2022年3月收治的92例乳腺癌患者作为恶性组,另选取同期114例良性乳腺结节患者作为良性组,均行SMI检查,统计对比两组的血流状况。结果... 详细信息

目的探讨超微血管显像(SMI)在乳腺癌早期诊断、病情判断及疗效评估中的价值。方法选取我院2020年4月至2022年3月收治的92例乳腺癌患者作为恶性组,另选取同期114例良性乳腺结节患者作为良性组,均行SMI检查,统计对比两组的血流状况。结果良性组的血流状况明显优于恶性组(pppp<0.05)。结论SMI技术可为乳腺癌的临床早期诊断、病情判断、疗效评估提供参考依据,便于临床制定针对性治疗方案。

关键词：乳腺癌超微血管显像血流状况

超声造影定量分析参数水平在甲状腺结节性质鉴别诊断中的价值

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中国民康医学 2024年第1期36卷 127-129页

作者：付饶安阳市人民医院超声科河南安阳455000

目的:分析超声造影(CEUS)定量分析参数水平在甲状腺结节性质鉴别诊断中的价值。方法:回顾性分析2020年2月至2022年2月该院收治的124例甲状腺结节患者的临床资料,所有患者均给予CEUS检查,以病理学检查结果为“金标准”,比较不同性质甲状... 详细信息

目的:分析超声造影(CEUS)定量分析参数水平在甲状腺结节性质鉴别诊断中的价值。方法:回顾性分析2020年2月至2022年2月该院收治的124例甲状腺结节患者的临床资料,所有患者均给予CEUS检查,以病理学检查结果为“金标准”,比较不同性质甲状腺结节、不同病理学特征甲状腺恶性结节患者CEUS检查参数[造影剂通过时间(MTT)、峰值强度(peak)、达峰时间(TIp)]水平,采用Spearman相关性分析CEUS定量分析参数水平与不同病理学特征甲状腺恶性结节的相关性。结果:病理学检查结果显示,124例甲状腺结节患者中,良性58例,恶性66例;不同性质甲状腺结节与周围正常组织MTT水平比较,差异均无统计学意义(p>0.05);恶性结节、良性结节peak水平低于周围正常组织,且恶性结节低于良性结节;恶性结节、良性结节TIp水平高于周围正常组织,且恶性结节高于良性结节,差异有统计学意义(pp>0.05);不同病理学特征甲状腺恶性结节peak水平比较,淋巴结转移的低于淋巴结未转移,临床分期Ⅲ~Ⅳ期的低于Ⅰ~Ⅱ期,浸润深度T_(3)~T_(4)的低于T_(1)~T_(2);不同病理学特征甲状腺恶性结节TIp水平比较,淋巴结转移的高于淋巴结未转移,临床分期Ⅲ~Ⅳ期的高于Ⅰ~Ⅱ期,浸润深度T_(3)~T_(4)的高于T_(1)~T_(2),差异有统计学意义(ppearman相关性分析结果显示,peak水平与淋巴结转移、临床分期、浸润深度均呈负相关(rpp水平与淋巴结转移、临床分期、浸润深度均呈正相关(r>0,p<0.05)。结论:CEUS定量分析参数水平可应用于甲状腺结节的性质诊断和病情评估。

关键词：超声造影定量分析参数甲状腺结节性质诊断

The Influence of Systematic Errors on the Asian Summer Monsoon Circulation

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Advances in Atmospheric Sciences 2000年第4期17卷 576-586页

作者： p. L. S. rao IBM India Research Laboratory Indian Institute of Technology

The systematic errors of wind field associated with the prediction of Asian summer monsoon and their impact on the monsoon circulation have been studied in this paper. The daily operational analyses and fore-casts (up to day-5) of the National Centre for Medium Range Weather Forecasting (NCMRWF), India, over the Asian summer monsoon domain for the period June, July and August of 1995 are made use for the purpose. The systematic errors associated with the low level flow delineate, reduction in the strength of trade winds leading to weakening of cross equatorial flow as well as westerly flow over Indian Ocean. The upper level errors connote weakening of Tibetan anticyclone and reduction in the strength of return flow into the Southern Hemisphere. Further, these errors evince growing tendency with increase in the forecast period. Apart from the general underestimation of kinetic energy budget terms, the model forecasts fail to represent the transient eddies. The forecasts show increasing trend in the conversion of eddy to mean kinetic energy. These errors enfeeble Asian summer monsoon circulation with increase in the forecast period. Key words Monsoon - Systematic errors - Kinetic energy budget The author is grateful to the NCMRWF for providing data and computing facilities to carry out the present study.

关键词： Monsoon Systematic errors Kinetic energy budget

Role of autoreactive Tc17 cells in the pathogenesis of experimental autoimmune encephalomyelitis

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Neuroprotection 2024年第1期2卷 49-59页

作者： Yong peng Xiuli Zhang Yandan Tang Shunqing He Guilan rao Quan Chen Yahui Xue Hong Jin Shu Liu Ziyang Zhou Yun Xiang Department of Neurology Affliated First Hospitalof HunanTraditional Chinese Medical CollegeZhuzhouHunanChina Department of Neurology The Third Affiliated Hospital of Hunan University of Chinese MedicineZhuzhouHunanChina Science and Technology Innovation Center HunanUniversityof ChineseMedicineChangshaHunanChina

Background:The pathogenesis of multiple sclerosis(MS)and experimental autoimmune encephalomyelitis(EAE-an animal model of MS)is primarily mediated by T ***,recent studies have only focused on interleukin(IL)-17-secreting CD4^(+)T-helper cells,also known as Th17 *** study aimed to compare Th17 cells and IL-17-secreting CD8^(+)T-cytotoxic cells(Tc17)in the context of MS/***:Female C57BL/6 mice were immunized with myelin oligodendrocyte glycoprotein peptides 35-55(MOG35-55),pertussis toxin,and complete Freund's adjuvant to establish the EAE animal model.T cells were isolated from the spleen(12-14 days postimmunization).CD4^(+)and CD8^(+)T cells were purified using isolation kit and then differentiated into Th17 and Tc17,respectively,using MOG35-55 and *** secretion levels of interferon-(IFN-γ)and IL-17 were measured via enzyme-linked immunosorbent assay using cultured CD4^(+)and CD8^(+)T cell *** pathogenicity of Tc17 and Th17 cells was assessed through adoptive transfer(tEAE),with the clinical course assessed using an EAE score(0-5).Hematoxylin and eosin as well as Luxol fast blue staining were used to examine the spinal *** CD8^(+)CD3^(+)and CD4^(+)CD3^(+)cells differentiated into Tc17 and Th17 cells,respectively,were stimulated with MOG35-55 peptide for proliferation ***:The results showed that Tc17 cells(15,951±19855VS.55,709±4196cpm;pponse to highest dose(20μg/mL)MOG35-55 than Th17 ***,this response was not dependent on Th17 *** the 48h stimulation,at the highest dose(20μg/mL)of ***17 cells secreted lower levels of IFN-(280.00±15.00vs.556.67±15.28pg/mL,ppg/mL vs.288.33±12.58 pg/mL;ppatterns were observed for IFN-γsecretion at 96 and ***,Tc17 cell-induced tEAE mice exhibited similar EAE scores to Th17 cell-induced tEAE mice and also showed similar inflammation and demyelinati

关键词： CD8^(+)T cells experimental autoimmune myelitis IFN-y IL-17 multiple sclerosis Tc17 cells

Effect of post Cryorolling Treatments on Microstructural and Mechanical Behaviour of Ultrafine Grained Al-Mg-Si Alloy

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Journal of Materials Science & Technology 2014年第10期30卷 998-1005页

作者： p.Nageswara rao Dharmendra Singh R.Jayaganthan Department of Metallurgical and Materials Engineering Indian Institute of Technology Roorkee

To investigate the effect of post cryorolling treatments on simultaneous enhancement in strength and ductility of ultrafine grained material （UFG）, AI 6061 alloy was subjected to cryorolling followed by warm rolling （CR ＋ WR） and compared with cryorolling followed by short annealing （CR ＋ SA） at the same temperature. Transmission electron microscopy （TEM） was used to characterize the microstructural features of the processed material. The mechanical properties were investigated through Vickers hardness testing and tensile testing at room temperature. TEM, X-ray diffraction （XRD） and differential scanning calorimetry （DSC） were used to investigate the precipitation evolution in UFG material. Results indicated that the alloy subjected to CR ＋ WR has shown improved mechanical properties （114 HV, ultimate tensile strength （UTS）： 350 Mpa） as compared to that in the case of CR ＋ SA （105 HV, UTS： 285 Mpa）. The size of the precipitates observed in CR ＋ WR sample after peak ageing treatment is finer than that of peak aged CR ＋ SA sample. The UTS of peak aged CR ＋ WR sample （UTS： 390 Mpa） was found to be higher than that of peak aged CR ＋ SA sample （UTS： 355 Mpa）, without decrease in ductility.

关键词： Aluminium alloy Cryorolling Warm rolling Short annealing Mechanical properties Differential scanning calorimetry (DSC)

Microstructures and impact toughness behavior of Al 5083 alloy processed by cryorolling and afterwards annealing

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International Journal of Minerals,Metallurgy and Materials 2013年第8期20卷 759-769页

作者： Dharmendra Singh p.Nageswara rao R.Jayaganthan Department of Metallurgical and Materials Engineering Indian Institute of Technology RoorkeeRoorkee-247667India

The influence of rolling at liquid nitrogen temperature and annealing on the microstructure and mechanical properties of Al 5083 alloy was studied in this paper. Cryorolled samples of Al 5083 show significant improvements in strength and hardness. The ultimate tensile strength increases up to 340 Mpa and 390 Mpa for the 30% and 50% cryorolled samples, respectively. The cryorolled samples, with 30% and 50% reduction, were subjected to Charpy impact testing at various temperatures from 190℃ to 100℃. It is observed that increasing the percentage of reduction of samples during cryorolling has significant effect on decreasing impact toughness at all temperatures by increasing yield strength and decreasing ductility. Annealing of samples after cryorolling shows remarkable increment in impact toughness through recovery and recrystallization. The average grain size of the 50% cryorolled sample （14 μm） after annealing at 350℃ for 1 h is found to be finer than that of the 30% cryorolled sample （25 μm）. The scanning electron microscopy （SEM） analysis of fractured surfaces shows a large-size dimpled morphology, resembling the ductile fracture mechanism in the starting material and fibrous structure with very fine dimples in cryorolled samples corresponding to the brittle fracture mechanism.

关键词： aluminum alloys cryorolling annealing microstructure impact toughness recovery recrystallization

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隧道洞外减光棚光学参数优化分析研究

地下空间与工程学报 2024年第4期20卷 1367-1374页

作者：万利饶炎马非山东省交通规划设计院集团有限公司济南250101 重庆科技大学建筑工程学院重庆401331

近年来越来越多的城市隧道和高速公路隧道在入洞口设置了减光棚装置,用来降低“黑洞效应”及低角度阳光眩光效应,从而提高隧道入口段的行车安全。现有的减光棚存在着路面均匀度差、明暗条纹、路面亮度不均匀等不良情况,给行车带来了一... 详细信息

近年来越来越多的城市隧道和高速公路隧道在入洞口设置了减光棚装置,用来降低“黑洞效应”及低角度阳光眩光效应,从而提高隧道入口段的行车安全。现有的减光棚存在着路面均匀度差、明暗条纹、路面亮度不均匀等不良情况,给行车带来了一定的负面影响。在综合考虑隧道减光棚安全性和舒适性的基础上,基于光扩散板的多光源效应,提出了降低减光棚负面影响技术,构建了减光棚日光直射数值分析模型,在减光棚顶部布设光扩散板,将日光充分扩散后照射到棚下路面,从而避免太阳直射路面导致的不良现象,通过室内试验和数值分析方法进行光学分析研究。结果表明:在光扩散板的作用下路面亮度均匀度在0.7~0.95,满足设计规范要求,能避免出现明暗条纹等不良现象,保证了隧道洞口处的行车安全和舒适性;由于采用自然光线提供光通量,可以通过光扩散板的布设面积控制棚下路面的亮度等级,降低了隧道照明系统的碳排放,实现了安全、舒适与低碳环保的统一。

关键词：隧道减光棚光扩散板安全舒适低碳