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基于确定性约束和局部空间自适应正则化的图像盲复原算法

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数据采集与处理 2002年第2期17卷 121-125页

作者：余昕杨绿溪邹采荣东南大学无线电系南京210096

给出了一种用于图像盲复原的基于非负支撑域受限递归逆滤波 (nas-RIF)算法的改进算法。通过在代价函数中加入空间自适应的正则化项来改进算法的抗噪性能和复原效果 ,并利用迭代算法的中间结果 ,进一步精确寻找图像边界 ,有效地达到了保... 详细信息

给出了一种用于图像盲复原的基于非负支撑域受限递归逆滤波 (nas-RIF)算法的改进算法。通过在代价函数中加入空间自适应的正则化项来改进算法的抗噪性能和复原效果 ,并利用迭代算法的中间结果 ,进一步精确寻找图像边界 ,有效地达到了保存边界并抑制噪声的目的。使用 n步重新开始的共轭梯度法可以提高算法的收敛速度。由实验结果可以看出 ,对于信噪比较低的退化图像 ,改进的 nas-RIF算法具有更好的复原效果和稳定性。

关键词：确定性约束图像盲复原算法逆滤波正则化空间自适应图像处理 nas-RIF算法

Towards a Comprehensive Search of putative Chitinases Sequences in Environmental Metagenomic Databases

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Natural Science 2014年第5期6卷 323-337页

作者： Aline S.Romao-Dumaresq Adriana M.Fróes Rafael R.C.Cuadrat Floriano p.Silva Alberto M.R.Dávila Laboratório de Biologia Computacional e Sistemas Instituto Oswaldo Cruz(IOC)FIOCRUZRio de JaneiroBrazil Laboratório de Bioquímica de proteínas e peptídeos Instituto Oswaldo Cruz(IOC)FIOCRUZRio de JaneiroBrazil pólo de Biologia Computacional e Sistemas Instituto Oswaldo Cruz(IOC)FIOCRUZRio de JaneiroBrazil

Chitinases catalyze the hydrolysis of chitin, a linear homopolymer of β-(1,4)-linked N-acetylglucosamine. The broad range of applications of chitinolytic enzymes makes their identification and study very promising. Metagenomic approaches offer access to functional genes in uncultured representatives of the microbiota and hold great potential in the discovery of novel enzymes, but tools to extensively explore these data are still scarce. In this study, we develop a chitinase mining pipeline to facilitate the comprehensive search of these enzymes in environmental metagenomic databases and also to explore phylogenetic relationships among the retrieved sequences. In order to perform the analyses, UniprotKB fungal and bacterial chitinases sequences belonging to the glycoside hydrolases (GH) family-18, 19 and 20 were used to generate 15 reference datasets, which were then used to generate high quality seed alignments with the MAFFT program. profile Hidden Markov Models (pHMMs) were built from each seed alignment using the hmmbuild program of HMMER v3.0 package. The best-hit sequences returned by hmmsearch against two environmental metagenomic databases (Community Cyberinfrastructure for Advanced Microbial Ecology Research and Analysis—CAMERA and Integrated Microbial Genomes—IMG/M) were retrieved and further analyzed. The NJ trees generated for each chitinase dataset showed some variability in the catalytic domain region of the metagenomic sequences and revealed common sequence patterns among all the trees. The scanning of the retrieved metagenomic sequences for chitinase conserved domains/signatures using both the Interpro and the RpS-BLAST tools confirmed the efficacy and sensitivity of our pHMM-based approach in detecting putative chitinases sequences. These analyses provide insight into the potential reservoir of novel molecules in metagenomic databases while supporting the chitinase mining pipeline developed in this work. By using our chitinase mining pipeline, a larg

关键词： Chitinase Metagenome pHMM Sequence Search

GaSe：AgGaSe_2晶体的光学性能及应用(英文)

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中国光学 2012年第1期5卷 57-63页

作者：古新安朱韦臻罗志伟 ANGELUTS A A EVDOKIMOV M G NAZAROV M M SHKURINOV A p ANDREEV Y M LANSKII G V SHAIDUKO A V KOKH K A SVETLICHNYI V A 国立交通大学中国台湾新竹30010 莫斯科国立大学俄罗斯莫斯科119991 俄罗斯科学院西伯利亚分院气候与生态系统监测研究所俄罗斯托木斯克634055 俄罗斯科学院西伯利亚分院矿物学和地质学研究所俄罗斯新西伯利亚630090 俄罗斯托木斯克洲立大学西伯利亚物理技术研究所俄罗斯托木斯克634050 中国科学院长春光学精密机械与物理研究所吉林长春130033

从GaSe:AgGaSe2熔体(质量掺杂浓度为10%)中生长的非线性光学晶体ε-GaSe:Ag晶体(质量掺杂浓度≤0.04%)是一种非中心对称晶体,可用于相位匹配频率转换。Ag的掺入使GaSe晶体的显微硬度提高了30%,从而使其可以在任意方向上进行切割和抛光... 详细信息

从GaSe:AgGaSe2熔体(质量掺杂浓度为10%)中生长的非线性光学晶体ε-GaSe:Ag晶体(质量掺杂浓度≤0.04%)是一种非中心对称晶体,可用于相位匹配频率转换。Ag的掺入使GaSe晶体的显微硬度提高了30%,从而使其可以在任意方向上进行切割和抛光。本文研究了GaSe:AgGaSe2晶体在可见、中红外及太赫兹波段的光学性能。实验证明:GaSe:AgGaSe2晶体的吸收系数是纯GaSe晶体的2倍,其CO2激光倍频效率是ZnGep2晶体的1.7倍。

关键词： GaSe:AgGaSe2晶体光学特性中红外波段 THz波段二次谐波振荡

对比每天1次与每天3次妥布霉素治疗肺囊性纤维化(TOpIC研究):一项随机对照研究

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世界核心医学期刊文摘（胃肠病学分册） 2005年第7期1卷 7-8页

作者： Smyth A. Tan K.H.- V. Hyman- Taylor p. 王志宇 Department of paediatrics Nottingham City Hospital Nottingham NG5 1PB United Kingdom Dr

Background: Intravenous tobramycin (three- times daily)is widely used for pu lmonary exacerbations in patients with cystic fibrosis who have chronic pseudomo nas aeruginosa infection. We undertook a double- blind, randomized controlled t rial to assess the safety and efficacy of once versus three- times daily tobram ycin in these patients. Methods: 244 patients from 21 cystic- fibrosis centres in the UK were randomly assigned to once or three- times daily tobramycin (with ceftazidime) for 14 days. Treatment was given as 30- min infusions of tobramyc in in 0.9% saline. primary outcome measure was change in forced expiratory vol ume in 1s (FEV1), over the 14 days of treatment, expressed as a percentage of th e predicted normal value for age, sex, and height. We also measured the change i n FEV1 expressed as a percentage of baseline. Secondary outcomes included change in serum creatinine. The study was powered for equivalence,and primary analysis was per protocol. Findings:219 patients (107 once daily, 112 three- times dail y) completed the study per protocol. None was lost to follow- up, although 20 d iscontinued intervention. Of 122 patients assigned to once daily treatment, thre e did not receive the study regimen. The mean change in FEV1 (% predicted) over 14 days was similar on the two regimens (10.4% [once daily] vs 10.0% [three - times daily]; adjusted mean difference 0.4% [95% CI - 3.3 to 4.1]). Mean % change in FEV1 from baseline was also similar in both treatments (21.9% v s 22.1% ; - 0.1% [- 8.0 to 7.9]). There was no significant difference in % change in creatinine from baseline (- 1.5% [once daily] vs 1.7% [three- times daily]). However, in children, once daily treatment was significantly less nephrotoxic than was thrice daily (mean % change in creatine - 4.5% [once daily] vs 3.7% [thrice daily]; adjusted mean difference - 8.0% , 95% CI - 15.7 to - 0.4). No patients developed hearing loss during the study, although two reported acute dizziness and were wit

关键词：囊性纤维化 TOpIC 百分比变化头孢他定绿脓假单胞菌诊疗中心基线水平静脉滴注预测值肾毒性

Search for the doubly charmed baryon ■

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Science China(physics,Mechanics & Astronomy) 2020年第2期63卷 8-22页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar p.Albicocco J.Albrecht F.Alessio M.Alexander A.Alfonso Albero G.Alkhazov p.Alvarez Cartelle A.A.Alves Jr S.Amato Y.Amhis L.An L.Anderlini G.Andreassi M.Andreotti F.Archilli J.Arnau Romeu A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann J.J.Back S.Baker V.Balagura W.Baldini A.Baranov R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov G.Bassi V.Batozskaya B.Batsukh A.Battig V.Battista A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter L.J.Bel V.Belavin S.Belin N.Beliy V.Bellee K.Belous I.Belyaev G.Bencivenni E.Ben-Haim S.Benson S.Beranek A.Berezhnoy *** D.Berninghoff H.C.Bernstein E.Bertholet A.Bertolin C.Betancourt F.Betti M.O.Bettler Ia.Bezshyiko S.Bhasin J.Bhom M.S.Bieker S.Bifani p.Billoir A.Birnkraut A.Bizzeti M.Bjφrn M.p.Blago T.Blake F.Blanc S.Blusk D.Bobulska V.Bocci O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk T.J.V.Bowcock C.Bozzi S.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu E.Buchanan A.Buonaura C.Burr A.Bursche J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese S.Cali R.Calladine M.Calvi M.Calvo Gomez A.Camboni p.Campana D.H.Campora perez L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini p.Carniti K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero R.Cenci J.Cerasoli M.G.Chapman M.Charles ph.Charpentier G.Chatzikonstantinidis M.Chefdeville V.Chekalina C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova M.Chrzaszcz A.Chubykin p.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek F.Cindolo p.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu p.Collins T.Colombo A.Comerma-Montells A.Contu N.Cooke G.Coombs S.Coquereau G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovska A.Crocombe M.Cruz Torres R.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D'Ambrosio A.Danilina p.d'Argent A.Davis O.De Aguiar Francisco K.De Bruyn S.De Capua M Centro Brasileiro de pesquisas Fisicas(CBpF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy physics Tsinghua UniversityBeijingChina School of physics State Key Laboratory of Nuclear physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy physics(IHEp) BeijingChina Institute of particle physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance LAL Univ.Paris-SudCNRS/IN2P3Universite Paris-SaclayOrsayFrance LpNHE Sorbonne Universite Paris Diderot Sorbonne Paris Cite CNRS/IN2P3ParisFrance I.physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat physik Technische Universitat DortmundDortmundGermany Max-planck-Institut für Kernphysik(MpIK) HeidelbergGermany physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari MonserratoItaly INFN Sezione di padova PadovaItaly INFN Sezione di pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic physics AmsterdamNetherlands Nikhef National Institute for Subatomic physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear physics polish Academy of Sciences KrakowPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakowPoland Natio

A search for the doubly charmed baryon ■^+cc is performed through its decay to theΛ^+c K^-π^+ final state,using proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7,8 and 13 *** data correspond to a total integrated luminosity of 9 fb^-*** significant signal is observed in the mass range from 3.4 to 3.8 GeV/c^*** limits are set at 95%credibility level on the ratio of the ■^+cc production cross-section times the branching fraction to that ofΛ^+c and ■^++cc *** limits are determined as functions of the ■^+cc mass for different lifetime hypotheses,in the rapidity range from 2.0 to 4.5 and the transverse momentum range from 4 to 15 GeV/c.

关键词： charmed baryons limits on production of particles charmed quarks experimental tests

Fast tailward flows in the plasma sheet boundary layer during a substorm on 9 March 2008:THEMIS observations

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Fast tailward flows in the plasma sheet boundary layer durin...

为高等教育信息化基础设施发展可持续的数据服务:要求和可吸取的经验(英文)

中国科学院地质与地球物理研究所第11届（2011年度）学术年会

作者： R.Nakamura E.V.panov W.Baumjohann M.Volwerk A.Retino B.Zieger V.Angelopoulos K.-H.Glassmeier J.p.McFadden D.Larson Space Research Institute Austrian Academy of Sciences GrazAustria Institute of Geophysics and planetary physics University of Califomia Los AngelesCaliforniaUSA Institut fr Geophysik und extraterrestrische physik Technische Universitt Braunschweig BrunswickGermany Space Science Laboratory University of California BerkeleyCaliforniaUSA

[1]Tailward flows in the plasma sheet boundary layer(pSBL) were observed simultaneously by the five Time History of Events and Macroscale Interactions during Substorms(THEMIS) probes at down-tail distances X.6 to 7.6 R for 0 min during an interval of successive substorm intensification in a storm time on 9 March 2008. The flows first occurred close to Earth and then propagated along the magnetic field lines in the pSBL with a speed of 50-350 km *** show that the occurrence of tailward flows is highly dependent on proximity to the plasma sheet *** speeds occurred in the outer part of the pSBL,while either lower tailward speeds(or even earthward flows) were seen in the inner part of the *** tailward flow occurrence increased during magnetotail stretching and decreased or ceased during magnetic field *** pSBL tailward flows near the Earth can be understood as an outflow of the earthward flows that essentially empty the central plasma *** tailward flows along the field line filled the void left behind by the dipolarization front.

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科研信息化技术与应用 2014年第1期5卷 16-34页

作者： Wilfred W.Li Richard L.Moore Matthew Kullberg Brian Battistuz Steve Meier Ronald Joyce Richard p.Wagner Tad Reynales Qian Liu San Diego Supercomputer Center UC San Diego La JollaCA 92093 USA Qualcomm Institute UC San Diego La Jolla CA 92093 USA

美国加州大学圣迭戈分校(UCSD)的科研信息化基础设施(RCI)项目的目标是在集中存储、主机托管、计算、数据管理、联网和技术服务等方面为师生员工提供长期优质的服务。在2012年9月到2013年2月之间,为了确定数据存储的要求以及工作优先排... 详细信息

美国加州大学圣迭戈分校(UCSD)的科研信息化基础设施(RCI)项目的目标是在集中存储、主机托管、计算、数据管理、联网和技术服务等方面为师生员工提供长期优质的服务。在2012年9月到2013年2月之间,为了确定数据存储的要求以及工作优先排序,RCI数据服务团队(RCIDS)与多名教师和高级职员进行了一系列访谈。这些采访涉及了圣迭戈分校的29个独立的部门和科研单位,有50个不同的小组参加,共代表了600多名研究人员。这些研究小组的各样数据,从人类基因组序列,海洋天然产物,到宇宙模拟实验,是与全球成千上万用户分享的。根据这些访谈的结果,我们总结了圣迭戈分校研究人员对数据服务的10个要求以及5个现有的挑战与风险。RCIDS提出在一个可持续的商业模式下,首先部署网络附加存储(nas)数据服务;然后,再通过进一步的讨论以及考虑新兴的云计算技术来确定更长远的服务计划;最后,我们对于建立可持续性的高等教育e-科学基础设施的实施方案,基于云计算的数据服务,以及可吸取的经验教训提供了广泛的讨论。

关键词：高等教育科研信息化基础设施云数据可持续的数据服务网络附加存储

为高等教育信息化基础设施发展可持续的数据服务:要求和可吸取的经验(英文)

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数据与计算发展前沿 2014年第1期5卷 16-34页

关键词：高等教育科研信息化基础设施云数据可持续的数据服务网络附加存储

低N含量Ganas新型光电子材料中E+能级的奇特光学性质研究

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低N含量GaNAs新型光电子材料中E+能级的奇特光学性质研究