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From BIM model to 3D construction printing:A framework proposal

Frontiers of Architectural Research 2024年第4期13卷 912-927页

作者： Rodrigo García-Alvarado pedro Soza Ginnia Moroni Fernando pedreros Martín Avendaño pablo Banda Cristian Berríos Depto.Diseño y Teoría de la Arquitectura Universidad Del Bío-BíoConcepciónChile Depto.Arquitectura Universidad de ChileSantiagoChile Facultad de Ingeniería Arquitectura y DiseñoUniversidad San SebastiánConcepciónChile Facultad de Arquitectura Arte y DiseñoUniversidad Diego PortalesSantiagoChile

The growth of 3D construction printing needs appropriate integration into the planning and execution phases of building *** this aim,the Architecture,Engineering,and Construction sector(AEC)has been increasingly adopting building information modeling(BIM)systems to synchronize design and construction *** study proposes a technical workflow to manage 3D construction printing into BIM models,evaluating various procedures according to construction element *** on mature software platforms,the research details the data transfer process using a case study of a single-story *** case delves into design procedures for constructing walls of varied shapes,adjustments in width,joints,openings,textures,fillings,and the insertion of reinforcements and services while also discussing requirements of other building *** steps for managing design information and controlling printing machines are *** study’s outcome presents a comprehensive information flow,encompassing model segmentation,geometric data transfer,adjustments of details,and the generation of printing ***,it is offered a discussion that underlines the importance of a synergistic digital information flow that merges both design and execution phases,promoting construction efficiency and the embrace of innovative *** contribution of the paper focuses on technical design strategies for 3D construction printing,but also on suggesting an integrated process.

关键词： 3D construction printing Additive manufacturing Architectural design BIM

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Rainfall Sensitivity to Microphysics and planetary Boundary layer parameterizations in Convection-permitting Simulations over Northwestern South America

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Journal of Meteorological Research 2024年第4期38卷 805-825页

作者： K.Santiago HERNANDEZ Sebastian GOMEZ-RIos Juan J.HENAO Vanessa ROBLEDO Alvaro RAMiREZ-CARDONA Angela M.RENDON Geolimna Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Grupo de Ingenieria y Gestion Ambiental(GIGA) Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Division of Atmospheric Sciences Desert Research InstituteRenoNV 89512USA

Convection-permitting modeling allows us to understand mechanisms that influence rainfall in specific ***,microphysics parameterization(Mp) and planetary boundary layer(pBL) schemes remain an important source of uncertainty,affecting rainfall intensity,occurrence,duration,and ***,we study the sensitivity of rainfall to three Mp [Weather Research and Forecasting(WRF) Single-Moment 6-class(WSM6),Thompson,and Morrison] and two pBL [the Yonsei University(YSU) and Mellor–Yamada Nakanishi Niino(MYNN)] schemes with a convection-permitting resolution(4 km) over northwestern South America(NWSA).Simulations were performed by using the WRF model and the results were evaluated against soundings,rain gauges,and satellite data,considering the spatio-temporal variability of rainfall over diverse regions prone to deep convection in *** and pBL schemes largely influenced simulated rainfall,with better results for the less computationally expensive WSM6 Mp and YSU pBL *** rain gauges and satellite estimates,simulations with Morrison Mp overestimated rainfall,especially westward of the Andes,whereas the MYNN pBL underestimated precipitation in the Amazon–Savannas *** found that the uncertainty in the rainfall representation is highly dependent on the region,with a higher influence of Mp in the Colombian pacific and pBL in the Amazon–Savannas *** analyzing rainfall-related processes,the selection of both Mp and pBL parameterizations exerted a large influence on the simulated lower tropospheric moisture flux and moisture *** schemes significantly influenced the downward shortwave radiation,with MYNN simulating a greater amount of low clouds,which decreased the radiation ***,latent heat fluxes were greater for YSU,favoring moist convection and *** schemes had a marked impact on vertical ***,Morrison Mp showed stronger convection and higher precipitation rates,which is assoc

关键词： sensitivity microphysics planetary boundary layer(pBL) Weather Research and Forecasting(WRF) processes

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Vector-valued operators, optimal weighted estimates and the C_p condition

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Science China Mathematics 2020年第7期63卷 1339-1368页

作者： María Eugenia Cejas Kangwei Li Carlos pérez Israel pablo Rivera-Ríos BCAM—Basque Center for Applied Mathematics Bilbao 48009Spain CONICET Departamento de MatematicaFacultad de Ciencias ExactasUniversidad Nacional de La PlataLa Plata 1900Argentina Department of Mathematics University of the Basque CountryBilbao 48080Spain Ikerbasque Basque Foundation of ScienceBilbao 48013Spain INMABB CONICETDepartamento de MatematicaUniversidad Nacional del SurBahia Blanca 8000Argentina

In this paper some new results concerning the C_p classes introduced by Muckenhoupt(1981)and later extended by Sawyer(1983),are *** particular,we extend the result to the full expected range p>0,to the weak norm,to other operators and to their vector-valued *** of those results rely upon sparse domination,which in the vector-valued case are provided as *** will also provide sharp weighted estimates for vector-valued extensions relying on those sparse domination results.

关键词： A_p weights quantitative estimates C_p estimates vector-valued extensions sparse domination maximal functions Calderon-Zygmund operators commutators

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Sources,characteristics,toxicity,and control of ultrafine particles:An overview

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Geoscience Frontiers 2022年第1期13卷 512-526页

作者： Andrea L.Moreno-Ríos Lesly p.Tejeda-Benítez Ciro F.Bustillo-Lecompte Department of Civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia Research Group in Biomedical Toxicological and Environmental Sciences(Biotoxam)University of CartagenaCampus of ZaragocillaCartagenaColombia School of Occupational and public Health Ryerson University350 Victoria StreetTorontoON M5B 2K3Canada

Air pollution by particulate matter(pM)is one of the main threats to human health,particularly in large cities where pollution levels are continually *** to their source of emission,geography,and local meteorology,the pollutant particles vary in size and *** particles are conditioned to the aerodynamic diameter and thus classified as coarse(2.5–10μm),fine(0.1–2.5μm),and ultrafine(particles can get into the lungs and translocate into vital organs due to their size,causing significant human health ***,pM pollutants have been linked to respiratory conditions,genotoxic,mutagenic,and carcinogenic activity in human *** paper presents an overview of emission sources,physicochemical characteristics,collection and measurement methodologies,toxicity,and existing control mechanisms for ultrafine particles(UFps)in the last fifteen years.

关键词： particulate matter Ultrafine particles Air pollution Toxicity Measurement methodologies

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Intravitreal dexamethasone implants for diabetic macular edema

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International Journal of Ophthalmology(English edition) 2018年第1期11卷 77-82页

作者： Alicia pareja-Ríos paloma Ruiz-de la Fuente-Rodríguez Sergio Bonaque-González Maribel López-Gálvez Virginia Lozano-López pedro Romero-Aroca University Hospital of the Canary Islands Santa Cruz deTenerifeIslas Canarias 38320Spain Wooptix S.L San Cristobal de La Laguna 38204Spain University Clinical Hospital of Valladolid Institute of Applied Ophthalmobiology(IOBA)Valladolid 47011Spain University Hospital Sant Joan de Reus Tarragona 43204Spain

AIM： To evaluate the safety and efficacy of a dexamethasone（DEX） intravitreal implant for diabetic macular edema（DME）.METHODS： Totally 113 eyes of 84 patients were divided in three subgroups： naive patients（n=11）, pseudophakic patients（n=72） and phakic patients（n=30）. Inclusive criterion comprised adult diabetic patients with central fovea thickening and impaired visual acuity resulting from DME for whom previous standard treatments showed no improvement in both central macular thickness（CMT） and best corrected visual acuity（BCVA） after at least 3 mo of treatment. Outcome data were obtained from patient visits at baseline and at months 1, 3, 5, 9 and 12 after the first DEX implant injection. At each of these visits, patients underwent measurement of BCVA, a complete eye examination and measurement of CMT and macular volume（MV） carried out with optical coherence tomography（OCT） images. RESULTS： Seventy-three eyes（64.5%） received a single implant, 30（26.5%） received two implants and 10（9%） received three implants. At baseline, average in BCVA, CMT and MV were 43.5±20.8, 462.8±145 and 12.6±2.5 respectively. These values improved significantly at 1 mo（BCVA： 47.2±19.5, CMT： 339.6±120, MV： 11.11±1.4） and 3 mo（BCVA： 53.2±18.1, CMT： 353.8±141, MV： 11.3±1.3）（p≤0.05）. At 5 mo（BCVA： 50.9±19.8, CMT： 425±150, MV： 12.27±2.3）, 9 mo（BCVA： 48.4±17.6, CMT： 445.5±170, MV： 12.5±2.3） and 12 mo（BCVA： 47.7±18.8, CMT： 413.2±149, MV： 12.03±2.5）, improvements in the three parameters were no longer statistically significant and decreased progressively but did not reach baseline values. There were no clinical differences between subgroups. Ocular complications were ***： patients with DEX implants show maximum efficacy at 3 mo which then declined progressively, but is still better than baseline values at the end of follow-up.

关键词： Ozurdex diabetic macular edema dexamethasone retina diabetes

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Hidden diversity of marine borderline lichens and a new order of fungi:Collemopsidiales(Dothideomyceta)

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Fungal Diversity 2016年第5期80卷 285-300页

作者： Sergio pérez-Ortega Isaac Garrido-Benavent Martin Grube Rocío Olmo Asunción de los Ríos Museo Nacional de Ciencias Naturales(CSIC) Serrano 115 dpdoE-28006 MadridSpain Real Jardín Botánico de Madrid(CSIC) Plaza Murillo 2E-28014 MadridSpain Institute of plant Sciences University of GrazHolteigasse 6A-8010 GrazAustria Facultad de Ciencias Ambientales y Bioquímica Universidad de Castilla-La ManchaAvenida de Carlos III s/n45071 ToledoSpain

The fungal genus Collemopsidium comprises species that develop so-called borderline lichen symbioses with algae or *** with morphologically similar pyrenocarpous fungi it has been assigned to the family *** adscription of this family to higher taxonomic ranks remain *** sequence data of five nuclear genomic regions(nuLSU,nuSSU,tef1-α,rpb1 and rpb2)and onemitochondrial locus(mtSSU)we found that the studied representatives of this family are placed in the Dothideomyceta,yet relationships with the classes Dothideomycetes and Arthoniomycetes remain *** describe the new order Collemopsidiales to accommodate the genus Collemopsidium(paraphyletic as currently understood)and the lichenicolous genus *** five fungal fossils as calibrations points,we infer an age of c.230 Mya for the crown of *** on two molecular markers,we also provide insight into the global diversity of marine species of the genus *** to the species delimitation algorithm GMYC,c.26 putative species exist,far more than the six species recognized *** have confirmed this result by comparing the two alternative species models by means of Bayes factors,using path sampling and stepping-stone sampling algorithms to estimate the marginal likelihood of each ***,our observations suggest rock-boring ability evolved in parallel in the different lineages within this group of fungi.

关键词： Borderline lichens Dothideomycetes Endolithics.Lichen-forming fungi Lichenicolous fungi Boring ability Marine fungi Model comparison

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Real World Evidence (RWE, Real World Data), of the Effectiveness of Amoxicillin-Clavulanate in the Treatment of Children with Upper Respiratory Tract Infections (Tonsillitis, Otitis, Sinusitis)

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Open Journal of Respiratory Diseases 2024年第3期14卷 77-89页

作者： Maria Gonzalez Yibirin Juan Chirinos David Alberto Rincón Matute Trinidad Coll Miriam Rosales Yuliana Guevara Kuanlin Doried Guitens pérez Mauribel Figueroa Rosalía Romero Jurgensen Andrea Rojas Gabriel Jesús Arismendi González Milagros Salcedo Marife Martina Marin Marcano Carolina Mendoza Marycarmen Anuel Maria Morao Raymond Aguilera Diego Ríos Maryenis Rodríguez Loren Sánchez Jennyfer Fernández Rafael González Zaidith Zerpa Nelson Rodríguez Mirluis Rojas Sixtaime Quijada Mariangel Moya Diego Orsini Chris Gómez Hector Gamero José Rodríguez laboratorios LETI S.A.V. Guarenas Venezuela Ambulatorio Rural tipo II CpT3 Pampatar Venezuela Ambulatorio Los Robles CpT Dr. Luis Rosas Bravo Los Robles Venezuela Clnica prevaler Pampatar Venezuela Hospital tipo 1 Dr. David Espinoza Rojas en Salamanca Salamanca Venezuela Centro Mdico Rotary El Valle Venezuela Ambulatorio Rural Tipo II CpT3 Dr. Enrique Albornoz lares La Asuncin Venezuela

Real-world evidence (RWE) is clinical evidence on a medical product’s safety and efficacy that is generated using real-world data (RWD) resulting from routine healthcare delivery. This study evaluates the clinical efficacy of amoxicillin + clavulanic acid in children with pharyngitis, acute otitis, or acute rhinosinusitis with suspected bacterial origin under normal office and home conditions. Methods: This was a real-life, prospective, observational, pharmacovigilance study. It included children of both sexes between 2 and 12 years old, with a diagnosis of Rhinopharyngitis (tonsillitis), Acute Otitis Media and Rhinosinusitis. The main effectiveness variable evaluated was reduction and time to resolution of symptoms. All patients received Amoxicillin/Clavulanic Acid suspension 600 mg/42.9 mg/5 mL at a dose of 90 mg/Kg/day in two doses, every 12 hours for 7 days. The evaluations were carried out at the beginning, at 72 hours (3rd day) and at 7 days. All patients underwent culture and antibiogram. Results: The majority of cultures were negative for pathogenic germs, suspecting unidentifiable germs, or viral etiology despite the rigorous selection of subjects following validated scores. The most frequently isolated germ was Staphylococcus aureus;growth of gram-negative bacteria was reported in 33.33% of the cultures. There was a significant improvement in symptoms in children with tonsillitis and rhinosinusitis from the first 72 hours of treatment, persisting until the 7 days. In the otitis media group, returning to normal by the tenth day. During the conduction of this investigation, no adverse effects associated with the prescribed therapy were reported.

关键词： Amoxicillin Clavulanic Acid Tonsillitis Otitis Sinusitis

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Treatment of posterior urethral distractions defects following pelvic fracture

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Asian Journal of Urology 2018年第3期5卷 164-171页

作者： Emilio Ríos Luís Martínez-pineiro Department of Urology Universitary Hospital Infanta SofiaMadridSpain Department of Urology Universitary Hospital La PazMadridSpain

posterior urethral injuries typically arise in the context of a pelvic *** urethrography is the preferred diagnostic test in trauma patients with pelvic fracture where a posterior urethral rupture is *** fractures however preclude the adequate positioning of the patient on the X-ray table on admission and computed tomography scan with intravenous contrast and delayed films generally performed *** bladder catheter placement under ultrasound guidance should be performed whenever a posterior urethral disruption is *** diagnosis and proper acute management decrease the associated complications,such as strictures,urinary incontinence and erectile *** correct and appropriate initial treatment of associated urethral rupture is critical to the proper healing of the *** of a suprapubic cystostomy on admission and delayed anastomotic urethroplasty after 3e6 months continues to be the gold standard of *** this paper,we provide a comprehensive review of the literature with a special emphasis on the various treatments available:Open or endoscopic primary realignment,immediate or delayed urethroplasty after suprapubic cystostomy,and delayed optical urethrotomy.

关键词： posterior urethral injuries Distractions defects pelvic fracture Realignment Urethroplasty Optical urethrotomy

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On the Differential polynomial of a Graph

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Acta Mathematica Sinica,English Series 2019年第3期35卷 338-354页

作者： Ludwin A.BASILIO-HERNáNDEZ Walter CARBALLosA Jesús LEA?os José M.SIGARRETA Unidad Académica de Matemáticas Universidad Autónoma de Zacatecas Calzada Solidaridad entronque Paseo a la Bufa Department of Mathematics and Statistics Florida International University Department of Mathematics Miami Dade College Facultad de Matemáticas Universidad Autónoma de Guerrero

We introduce the differential polynomial of a graph. The differential polynomial of a graph G of order n is the polynomial B(G; x) :=∑?(G)k=-nB_k(G) x^(n+k), where B_k(G) denotes the number of vertex subsets of G with differential equal to k. We state some properties of B(G;x) and its *** particular, we compute the differential polynomial for complete, empty, path, cycle, wheel and double star graphs. We also establish some relationships between B(G; x) and the differential polynomials of graphs which result by removing, adding, and subdividing an edge from G.

关键词： Graph polynomial differential of a graph

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CCT各亚基在甲状腺癌中的表达及其对患者临床预后、肿瘤微环境和化疗药物敏感性的影响

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中国肿瘤生物治疗杂志 2024年第9期31卷 895-906页

作者：施晓辉白云峰塔拉白银宝顾佳慧内蒙古自治区人民医院肿瘤中心甲状腺肿瘤外科内蒙古呼和浩特010000 内蒙古科技大学包头医学院研究生院内蒙古包头014000

目的:探究含t-复合物1的伴侣蛋白(CCT)的8个亚基在甲状腺癌(TC)组织中的表达及其与TC分期、患者预后、免疫细胞浸润、免疫检查点表达和化疗药物敏感性的相关性。方法:采用TCGA数据库数据分析CCT各亚基在TC组织和癌旁组织中的表达;用TCG... 详细信息

目的:探究含t-复合物1的伴侣蛋白(CCT)的8个亚基在甲状腺癌(TC)组织中的表达及其与TC分期、患者预后、免疫细胞浸润、免疫检查点表达和化疗药物敏感性的相关性。方法:采用TCGA数据库数据分析CCT各亚基在TC组织和癌旁组织中的表达;用TCGA数据库数据分析CCT各亚基表达与TC患者预后的关系;用GSEA法分析CCT各亚基的生物学功能;用TCGA和TIMER2.0数据库数据分析CCT各亚基表达与肿瘤微环境、免疫细胞浸润、化疗药物敏感性、免疫检查点表达的相关性。结果:数据库数据分析显示,在TC组织中CCT3、CCT7和CCT8 mRNA均呈高表达(ppppppppos的独立预后生物标志物;CCT各亚基mRNA表达主要富集于移植物排斥、补体和干扰素-γ等信号通路;CCT各亚基mRNA低表达组TC组织的基质、免疫和综合评分均显著高于高表达组(pppppppppppppD-1、pD-L1、pD-L2、CTla4、CD80和CD86表达均有明显关联(ppp<0.001)。结论:CCT复合物可能通过影响肿瘤微环境促进TC的发生发展,进而影响患者预后,其可成为难治性TC诊断和免疫治疗的潜在靶点。

关键词：甲状腺癌 CCT复合物预后免疫细胞浸润药物敏感性

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