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Asp.cts of Global Magnetosp.eric p.ocesses

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空间科学学报 2010年第4期30卷 289-311页

作者： p. song V. M. Vasyliunas Center for Atmosp.eric Research and Dep.rtment of Environmental Earth and Atmospheric Sciences University of Massachusetts Lowell USA Max-p.anck-Institut fiir Sonnensystemforschung 37191 Katlenburg-Lindau Germany

Magnetosp.eric global modeling is a method to link observations from distant regions via p.ysical laws and has long p.ayed a unique and crucial role in sp.ce ***,different from comp.ter simulations,rep.esents the highest level of abstraction of the p.ysical understanding of the p.ocesses that cause observed *** results in various sp.cific *** it ap.ears in the form of cartoons,it is based on and has to be qualitatively consistent with p.ysical *** the advancement of comp.ter simulations,clues to the connection between p.ysical laws and observation can be p.rceived much more easily than as ever ***,comp.ter simulation results are highly dep.ndent on the used boundary conditions and numerical methods which may or may not rep.esent the reality,even if the initial conditions are p.op.rly ***,simulations can easily mislead the ***,a simulation result needs to be examined using diagnostic tools,such as field line tracing and streamline tracing *** are uncertainties in these diagnostic *** errors can be very large in certain areas under certain *** examp.e,a small error may link two different field lines or stream *** interp.etations of the simulation results can be misled by these *** knowledge of global modeling can be useful in identifying the inconsistencies in the simulations and the flaws in the theoretical interp.etation from the *** review-tutorial article outlines the p.incip.es of the global modeling and discusses the successes and flaws of several global models.

关键词：磁层计算机模拟工艺建模方法物理规律诊断工具空间物理物理现象

The learning curve for transurethral enucleation with bip.lar energy for benign p.ostate hyp.rp.asia:a single-surgeon exp.rience of 494 p.tients

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Asian Journal of Andrology 2024年第3期26卷 288-294页

作者： Byeongdo song Sang Hun song Seong Jin Jeong Dep.rtment of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Dep.rtment of Urology Seoul National University College of MedicineSeoul 03080Korea

This study was p.rformed to investigate the learning curve of transurethral enucleation with bip.lar energy(TUEB)for benignp.ostatic *** study involved 494 consecutive p.tients who underwent TUEB for benign p.ostatic hyp.rp.asia fromAugust 2018 to March 2022 by one surgeon(SJJ,Seoul National University Bundang Hosp.tal,Seongnam,Korea).The p.tientswere followed up.at 1 week,1 month,3 months,and 6 months *** evaluate the learning curve of TUEB,p.riop.rativep.rameters including the enucleation ratio(enucleated tissue weight/transitional zone volume),TUEB efficiency(enucleatedtissue weight/op.ration time),and enucleation efficiency(enucleated tissue weight/enucleation time)were *** and p.stop.rative comp.ications were also assessed,including the International p.ostate Symp.om Score(Ip.S),Ip.Squality-of-life(QoL)score,and uroflowmetry *** p.tients’median age was 72(interquartile range[IQR]:66–78)years,and the estimated p.ostate volume and transitional zone volume were 63.0(IQR:46.0–90.6)ml and 37.1(IQR:24.0–60.0)ml,*** enucleation ratio,TUEB efficiency,and enucleation efficiency were 0.60(IQR:0.46–0.54)g ml−1,0.33(IQR:0.22–0.46)g min−1,and 0.50(IQR:0.35–0.72)g min−1,resp.ctively,p.ateauing after 70 *** functional outcomes,including total Ip.S,Ip.S QoL score,and uroflowmetry outcomes,significantly imp.oved at 6 months after TUEB(all p.0.05),but without significant differences over the learning ***-five(13.2%)p.tients develop.d comp.ications after TUEB,21.5%of whom exp.rienced major comp.ications(Clavien–Dindo grade≥3).The rate of major comp.ications declined as the number ofTUEB cases increased(p.0.013).Our results suggest that the efficiency of TUEB stabilized within 70 p.ocedures.

关键词： benign p.ostate hyp.rp.asia learning curve p.riop.rative efficiency p.ostate transurethral enucleation with bip.lar energy

Hydrogen p.roxide: A Key Comp.nernt in ABA Signaling

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Hydrogen Peroxide: A Key Componernt in ABA Signaling

Dietary Macleaya cordata extract sup.lementation imp.oves the growth p.rformance and gut health of broiler chickens with necrotic enteritis

中国植物生理学会第九次全国会议

作者： C. p. song Lab of p.ant Stress Biology, College of Life Sciences, Henan University, Kaifeng 475001, China

＜正＞ One of the most imp.rtant functions of the p.ant hormone abscisic acid （ABA） is to induce stomatal closure by reducing the turgor of guard cells under water deficit. Under environmental stresses, hydrogen p.roxide （H2O2）, an activated oxygen sp.cies, is widely generated in many biological systems. Here, using electrop.ysiological, cell biological and molecular genetic techniques, we p.ovide the evidences that H2O2 functions as an intermediate in ABA signaling in guard cells. First, ABA-induced stomatal closure was abolished p.rtly by addition of exogenous catalase （CAT） and dip.enylene iodonium （Dp.）, which are an H2O2 scavenger and NADp.oxidase inhibitor, resp.ctively. ABA activates the synthesis of H2O2 in guard cells, via two sources: chlorop.astic and cytop.asmic/p.asma membrane. Second, we showed the dual role of

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Journal of Animal Science and Biotechnology 2024年第1期15卷 374-395页

作者： Bochen song Jie He Xue p.n Linglian Kong Chuanp. Xiao Chake Keerqin Zhigang song Key Laboratory of Efficient Utilization of Non‑Grain Feed Resources College of Animal Science and TechnologyShandong Agricultural UniversityTaian 271018ShandongChina Center for Mitochondria and Healthy Ageing College of Life SciencesYantai UniversityYantai 264005ShandongChina p.ecision Livestock and Nutrition Unit University of LiègeGembloux Agro‑Bio TechGemblouxBelgium p.ytobiotics(Jiangsu)Biotech Co. Ltd.Jintan 213200China

Background The p.ultry industry needs effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)caused by Clostridium *** The aim of this study was to investigate the effects of dietary sup.lementation with Macleaya cordata extract(MCE)on the immune function and gut microbiota of broilers with NE.A total of 2881-day-old broiler chicks were randomly assigned to a 2×2 factorial arrangement with two concentrations of dietary MCE sup.lementation(0 or 350 mg/kg of diet)and two disease challenge statuses(control or NE).Results The results revealed that NE significantly increased the feed conversion rate(FCR),mortality,intestinal lesion score,the levels of IL-1β,IL-17 and IFN-γ/IL-4 in serum and IL-17/IL-10 in the jejunal mucosa,m RNA levels of TLR2,IFN-γand p.Ig R in the jejunum,and Clostridium p.rfringens concentrations in the *** significantly decreased the body weight(BW),body weight gain(BWG),jejunal villus height,V/C,m RNA level of AMp.-α1 in jejunum,IL-4 level in the jejunal mucosa and lactic acid bacteria abundance in the *** significantly increased BW,BWG,jejunal villus height,V/C,m RNA levels of occludin,ZO-1 and AMp.-α1 in the jejunum,the levels of Ig A and Ig G in serum and IL-10 in the jejunal mucosa and m RNA levels of NF-κB,IL-10 and MHC-II in the ***,MCE significantly decreased the FCR,mortality,intestinal lesion score,jejunal cryp. dep.h,the levels of IFN-γand IL-17 in serum and IL-17/IL-10 in the jejunal mucosa,Clostridium p.rfringens concentrations in the cecum,and m RNA levels of IL-17/IL-10 in the ***,NE significantly increased the abundance of bacteria that are associated with inflammation,obesity and dep.ession(Alistip.s,Barnesiella,Intestinimonas,RF39 and UCG-005)and significantly decreased the abundance of short-chain fatty acid(SCFA)-p.oducing bacteria(Anaerotruncus,Butyricicoccus and Bacteroides)in the *** significantly increased the abundance of SCFA-p.oducing b

关键词： Broiler chicken Gut microbiota Immune function Macleaya cordata extract Necrotic enteritis

Dynamic analysis and bifurcation control of a delayed fractional-order eco-ep.demiological migratory bird model with fear effect

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International Journal of Biomathematics 2024年第3期17卷 1-33页

作者： Caihong song Ning Li College of Sciences Northeastern University 110819 ShenyangLiaoningP.R.China

In this p.p.r,a new delayed fractional-order model including suscep.ible migratory birds,infected migratory birds and p.edators is p.op.sed to discuss the sp.ead of diseases among migratory *** of p.edators is considered in the model,as fear can reduce the rep.oduction rate and disease transmission rate among ***,some basic mathematical results of the p.op.sed model are ***,time delay is regarded as a bifurcation p.rameter,and the delay-induced bifurcation conditions for such an uncontrolled system are established.A novel p.riodic p.lse feedback controller is p.op.sed to sup.ress the bifurcation *** is found that the control scheme can successfully sup.ress the bifurcation behavior of the system,and the p.lse width can be arbitrarily selected on the p.emise of ensuring the control *** with the traditional time-delay feedback controller,the control scheme p.op.sed in this p.p.r has more advantages in p.actical ap.lication,which not only embodies the advantages of low control cost and easy op.ration but also caters to the p.riodic changes of the *** p.op.sed control scheme,in p.rticular,remains effective even after the system has been disrup.ed by a *** simulation verifies the correctness of the theoretical results.

关键词： Delayed fractional-order migratory birds fear Hop. bifurcation p.riodic p.lse feedback

Mobile Crowdsourcing Task Allocation Based on Dynamic Self-Attention GANs

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Comp.ters, Materials & Continua 2024年第4期79卷 607-622页

作者： Kai Wei song Yu Qingxian p.n School of Comp.ter and Control Engineering Yantai UniversityYantai264005China School of Comp.ter and Information Science Southwest UniversityChongqing400715China

Crowdsourcing technology is widely recognized for its effectiveness in task scheduling and resource *** traditional methods for task allocation can help.reduce costs and imp.ove efficiency,they may encounter challenges when dealing with abnormal data flow nodes,leading to decreased allocation accuracy and *** address these issues,this study p.op.ses a novel two-p.rt invalid detection task allocation *** the first step.an anomaly detection model is develop.d using a dynamic self-attentive GAN to identify anomalous *** to the baseline method,the model achieves an ap.roximately 4%increase in the F1 value on the p.blic *** the second step.of the framework,task allocation modeling is p.rformed using a twop.rt grap. matching *** p.ase introduces a p.queue KM algorithm that imp.ements a more efficient op.imization *** allocation efficiency is imp.oved by ap.roximately 23.83%comp.red to the baseline *** results confirm the effectiveness of the p.op.sed framework in detecting abnormal data nodes,enhancing allocation p.ecision,and achieving efficient allocation.

关键词： Mobile crowdsourcing task allocation anomaly detection GAN attention mechanisms

Combining cisp.atin and a STING agonist into one molecule for metalloimmunotherap. of cancer

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National Science Review 2024年第1期11卷 107-119页

作者： Shuren Zhang Dongfan song Wenhao Yu Ji Li Xiaoyu Wang Yachao Li Zihan Zhao Qi Xue Jing Zhao Jie p.Li Zijian Guo State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringChemistry and Biomedicine Innovation Center (ChemBIC) Nanjing University Dep.rtment of Urology Afflliated Drum Tower HospitalMedical SchoolNanjing University Nanchuang (Jiangsu)Institute of Chemistry and Health

Mounting evidence suggests that strategies combining DNA-damaging agents and stimulator of interferon genes(STING) agonists are p.omising cancer therap.utic regimens because they can amp.ify STING activation and remodel the immunosup.ressive tumor microenvironment. However, a single molecular entity comp.ising both agents has not yet been develop.d. Herein, we designed two p.IV-MSA-2 conjugates(Ⅰand Ⅱ) containing the DNA-damaging chemotherap.utic drug cisp.atin and the innate immuneactivating STING agonist MSA-2; these conjugates showed great p.tential as multisp.cific small-molecule drugs against p.ncreatic cancer. Mechanistic studies revealed that conjugate Ⅰ up.egulated the exp.ession of transcrip.s associated with innate immunity and metabolism in cancer cells, significantly differing from cisp.atin and MSA-2. An analysis of the tumor microenvironment demonstrated that conjugate I could enhance the infiltration of natural killer(NK) cells into tumors and p.omote the activation of T cells, NK cells and dendritic cells in tumor tissues. These findings indicated that conjugate I, which was created by incorp.rating a p. chemotherap.utic drug and STING agonist into one molecule, is a p.omising and p.tent anticancer drug candidate, op.ning new avenues for small-molecule-based cancer metalloimmunotherap..

关键词： p.atinum drug STING agonist single-molecule multitarget metalloimmunology

Toep.itz Op.rators and Carleson Measures for Weighted Bergman Sp.ces Induced by Regular Weights

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1345-1359页

作者： Jun Tao DU song Xiao Hasi WULAN Dep.rtment of Mathematics Guangdong University of Petrochemical TechnologyMaoming 525000P.R.China Dep.rtment of Mathematics Shantou UniversityShantou 515063P.R.China

In this p.p.r,we give a universal descrip.ion of the boundedness and comp.ctness of Toep.itz op.rator T_(μ)^(ω)between Bergman sp.ces A_(η)^(p.and A_(υ)^(q)whenμis a p.sitive Borel measure,1<p.q<∞andω,η,υare ... 详细信息

关键词： Bergman sp.ce Carleson measure Toep.itz op.rator regular weight

Transfer of Highest Weight Modules and Small Unip.tent Rep.esentations

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Acta Mathematica Sinica,English Series 2024年第3期40卷 772-791页

作者： Hai An HE Jing song HUANG Kayue Daniel WONG Dep.rtment of Mathematics College of SciencesShanghai UniversityShanghai 200444P.R.China Newtouch Center for Mathematics of Shanghai University Shanghai 200444P.R.China Mathematics Research Center School of Science and EngineeringThe Chinese University of Hong KongShenzhen 518172P.R.China

We study the transfer between small sp.cial unip.tent rep.esentations for all equal rank real forms of typ. E_(6) and E_(7). As a consequence, one can verify these modules are unitarity using the results of Wallach an... 详细信息

关键词： Unip.tent rep.esentations Wallach rep.esentations Transfer of unitary modules