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Comparison of clinical outcomes of deep anterior lamellar keratoplasty and excimer laser assisted anterior lamellar keratoplasty in keratoconus

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 582-586页

作者： Kübra Serbest Ceylanoglu Bahri Aydin Mehmet Cuneyt ozmen Department of Ophthalmology Sincan State Hospital Department of Ophthalmology Gazi University Medical School

AIM: To compare and evaluate the clinical outcomes of deep anterior lamellar keratoplasty(DALK) and excimer laser assisted anterior lamellar keratoplasty(ELLK) in eyes with ***: In this study, 57 eyes of 56 patients operated between 2013 to 2017 were included. Thirty-one eyes underwent big-bubble DALK and twenty-six eyes underwent ELLK. Preoperative and at control visits complete ophthalmic examination was performed. RESULTS: The mean patient age at the time of DALK surgery was 27 y and mean follow-up period was 21±5.4 mo. The mean patient age at the time of ELLK surgery was 27 y and mean follow-up period was 40±18 mo. Mean best spectacle corrected visual acuity(BSCVA) at postoperative period was significantly higher for DALK group(0.66±0.11) versus ELLK group(0.4±0.2)(P<0.05). Descemet's membrane microperforation was occurred in 7 patients in DALK group versus in 1 patient in ELLK group. In 4 eyes, interface irregularity was developed in ELLK group. None of the patients in follow-up had graft rejection in both ***: In ELLK group, complication rate is lower, the surgical technique is simpler, faster and safer and also ELLK requires less experience with respect to DALK. Further, DALK can be performed unless satisfactory visual acuity is achieved after ELLK.

关键词： excimer laser assisted lamellar keratoplasty deep anterior lamellar keratoplasty big-bubble technique

Internal biliary fistula due to cholelithiasis:A single-centre experience

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World Journal of Gastroenterology 2007年第34期13卷 4606-4609页

作者： Arife Polat Duzgun Mehmet Mahir ozmen Mehmet Vasfi Ozer Faruk Coskun Department of 3rd Surgery Ankara Numune Teaching and Research Hospital Ankara Turkey

AIM： To discuss about the perioperative problems encountered in patients with internal biliary fistula （IBF） caused by cholelithiasis.METHODS： In our hospital, 4 130 cholecystectomies were carried out for symptomatic cholelithiasis from January 2000 to March 2004 and only 12 patients were diagnosed with IBF. The perioperative data of these 12 IBF patients were analyzed retrospectively.RESULTS： The incidence of IBF due to cholelithiasis was nearly 0.3%. The mean age was 57 years. Most of the patients presented with non-specific complaints. Only two patients were considered to have IBF when gallstone ileus was observed during the investigations. Nine patients underwent emergency laparotomy with a pre-operative diagnosis of acute abdomen. In the remaining three patients, elective laparoscopic cholecystectomy was converted to open surgery after identification of IBF. Ten patients had cholecystoduodenal fistula and two patients had cholecystocholedochal fistula. The mean hospital stay was 23 d. Two wound infections, three bile leakages and three mortalities were observed.CONCLUSION： Cholecystectomy has to be performed in early stage in the patients who were diagnosed as cholelithiasis to prevent the complications like IBF which is seen rarely. Suspicion of IBF should be kept in mind, especially in the case of difficult dissection during cholecystectomy and attention should be paid in order to prevent iatrogenic injuries.

关键词： Internal biliary fistula Cholecystoduodenalfistula Cholelithiasis Iatrogenic injuries

An unusual cause ofileal perforation:Report of a case and literature review

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World Journal of Gastroenterology 2009年第21期15卷 2672-2674页

作者： Sami Akbulut Bahri Cakabay Cihan Akgul ozmen Arsenal Sezgin Mahsuni Mert Sevinc Department of Surgery Diyarbakir Education and Research Hospital Department of Radiology Dicle University Faculty of Medicine Department of Pathology Diyarbakir Education and Research Hospital

An ileal perforation resulting from a migrated biliary stent is a rare complication of endoscopic stent placement for benign or malignant biliary tract *** describe the case of a 59-year-old woman with a history of abdominal surgery in which a migrated biliary stent resulted in an ileal *** with comorbid abdominal pathologies,including colonic diverticuli,parastomal hernia,or abdominal hernia,may be at increased risk of perforation from migrated stents.

关键词： Adhesion Biliary stent Ileal perforation Migration Choledocholithiasis

A histological study of rabbit corneas after transepithelial corneal crosslinking using partial epithelial photoablation or ethanol treatment

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 959-963页

作者： Mehmet Cuneyt ozmen Ahmet Hondur Guldal Yilmaz Kamil Bilgihan Berati Hasanreisoglu Department of Ophthalmology Gazi University Department of Pathology Gazi University

AIM: To evaluate the histological changes after transepithelial corneal crosslinking(CXL) using partial thickness excimer laser ablation or epithelial ethanol application in an experimental rabbit ***: Right eyes of twenty-four rabbits were studied. Four eyes received total epithelial debridement(group I). Four eyes received partial thickness epithelial ablation with excimer laser(group II). Twelve eyes were treated with different durations(30s and 60s) and concentrations(18% to 48%) of ethanol(group III).Riboflavin was applied for 30 min intervals along with topical proparacaine drops with benzalkonium chloride,and 370 nm irradiation was performed for 30 min, while riboflavin was instilled every 3min. Four eyes(group IV)received 48% ethanol for 30 s without riboflavin and irradiation. Eyes were collected after 24 h and examined ***: All eyes in group I showed keratocyte loss in the superficial 300 μ of corneal storma. In group II, 1-4layers of epithelium were preserved and no keratocyte loss occurred. In group III, CXL after treatment with ethanol up to 24% concentration and up to 60 s revealed no keratocyte loss. CXL after treatment with 48% and higher ethanol concentrations yielded keratocyte loss in the superficial 200 μ to 300 μ of ***: Incomplete excimer laser ablation of the epithelium or treatment with ethanol up to 24%concentration and up to 60 s duration yielded no stromal keratocyte loss. To get the same histological appearance seen in epithelial debridement group, partial thicknessexcimer laser epithelial ablation or ethanol application is not adequate for transepithelial CXL.

关键词： crosslinking keratoconus transepithelial photoablation ethanol histology

Retinal vessel diameters and their correlation with retinal nerve fiber layer thickness in patients with pseudoexfoliation syndrome

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International Journal of Ophthalmology(English edition) 2015年第2期8卷 332-336页

作者： Mehmet Cuneyt ozmen Zeynep Aktas Burcin Kepez Yildiz Murat Hasanreisoglu Berati Hasanreisoglu Department of Ophthalmology Gazi University Medical School

AIM: To compare retinal artery-vein diameters(RAVDs)of patients with pseudoexfoliation(PSX) syndrome with healthy controls and investigate the correlations between retinal nerve fiber layer(RNFL) thickness parameters and ***: Seventeen eyes with PSX and 17 eyes of age-matched controls were included in the study. All participants underwent routine ophthalmological examination, Humphrey visual field and RNFL examination by using Stratus OCT. Retinal images were obtained by using a retinal camera(Topcon 501X).RAVDs were measured from inferior nasal, inferior temporal, superior nasal and superior temporal arcuates by using IMAGEnet software. Superior, inferior, nasal,temporal and average RNFL thicknesses were *** and RNFL parameters in groups and correlations were analyzed by Mann-Whitney U and Spearmann correlation ***: Only inferior quadrant and average RNFL thickness were detected thinner in the PSX group compared with control group(P =0.009, P =0.038,respectively). No statistically significant difference regarding RAVDs was found between two ***: RAVDs seems to be comparable in the PSX and control group. RNFL is thinner in the inferior quadrant in the PSX group. RNFL thickness and RAVDs show significant correlations in both groups. This correlation doesn’t seem to be specific to PSX.

关键词： pseudoexfoliation retinal nerve fiber layer thickness retinal artery-vein diameters

Failure Rate of Adenoidectomy and Reasons of Failure in the Short Term

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International Journal of Otolaryngology and Head & Neck Surgery 2012年第2期1卷 14-17页

作者： Süay ozmen Omer Afsin ozmen Otorhinolaryngology Clinics Inegol Government HospitalBursaTurkey Department of Otorhinolaryngology Medical FacultyUludag UniversityBursaTurkey

Objectives: The aim of the present study was to analyze the recovery rate of symptoms in patients with adenoid hypertrophy and investigate the role of nasal pathologies, allergy and gastroesophageal reflux (GER) as the reason of failure in patients with persistent symptoms. Patients and Methods: Patients undergoing adenoidectomy were enrolled in this study. There were 58 males and 42 females, aged between 1 - 13 years (mean ± SD: 4.9 ± 2.2 years). The parents of each child were questioned about the following symptoms;apnea, nasal obstruction, mouth breathing, snoring and nasal discharge. Presence or absence of nasal obstruction due to septal deviation and/or chonchal hypertrophy was noted. All children were evaluated for GER by upper gastrointestinal endoscopy or pH monitorization and for allergy by specific IgE analysis or skin prick test. Three months after the operation the children were re-examined and their parents were interviewed about persistent symptoms. Patients with persistent symptoms were re-evaluated with rigid endoscopy for residual adenoid vegetation. Results: Apnea was cleared in the entire group postoperatively. However, 9 patients complained of nasal obstruction, 16 patients had mouth breathing, 9 patients had snoring and 17 patients continued to have nasal discharge two months after the operation. Statistical assessment showed a significant difference for each symptom between the pre- and postoperative level (p Conclusions: Adenoidectomy alone is an effective treatment for nasal obstruction and obstructive sleep symptoms in children. Persistent obstructive symptoms are usually due to nasal pathology and allergy.

关键词： Adenoidectomy Nasal Obstruction Snoring

In-vivo corneal biomechanical analysis of unilateral keratoconus

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International Journal of Ophthalmology(English edition) 2015年第6期8卷 1141-1145页

作者： Orhan Ayar Mehmet Cuneyt ozmen Orkun Muftuoglu Mehmet Orcun Akdemir Mustafa Koc Kemal Ozulken Department of Ophthalmology Bulent Ecevit University Department of Ophthalmology Gazi University Department of Ophthalmology Medipol University Ulucanlar Eye Research and Education Hospital Kudret Eye Hospital

AIMTo evaluate and compare corneal biomechanical findings measured by ocular response analyzer, topographic and pachymetric findings in patients with unilateral keratoconus patients and healthy *** is an observational, case-control study. Patients with keratoconus in one eye and forme fruste keratoconus in the fellow eye were compared with sex and age matched with controls healthy subjects. All subjects were evaluated with rotating scheimpflug imaging system. The receiver-operating-characteristic curves were analyzed to evaluate the sensitivity and specificity of the ***-seven patients with keratoconus in one eye and forme fruste keratoconus in the fellow eye were compared with 40 eyes of 40 normal subjects. Corneal hysteresis (CH) was 8.0±1.7 mm Hg in keratoconus group, 8.3±1.6 mm Hg in forme fruste keratoconus group, and 9.8±1.6 mm Hg in control groups (P=0.54 between keratoconus and forme fruste keratoconus groups, P<0.01 between control group and other groups). Corneal resistance factor (CRF) was 7.1±2.2 mm Hg in keratoconus group, 7.8±1.2 mm Hg in forme fruste keratoconus group and 9.9±1.5 mm Hg in control group (P<0.001 between control group and other groups). Using receiver-operating-characteristic analysis, the area under curve values of the parameters to distinguish forme fruste keratoconus from control subjects were: CH (0.768), CRF (0.866). Best cut-off points were 9.3 mm Hg and 8.8 mm Hg for CH and CRF *** response analyzer parameters (CH and CRF) are found to be significantly lower in forme fruste keratoconus patients compared to normal control subjects.

关键词： forme fruste keratoconus keratoconus ocular response analyzer

Ataxia telangiectasia in Turkey:multisystem involvement of 91 patients

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World Journal of Pediatrics 2017年第5期13卷 465-471页

作者： Hacer Akturk Murat Sutcu Ayper Somer Sanem Piskin Manolya Acar Meral ozmen Umut Altinoglu Burak Tatli Nuran Salman Department of Pediatric Infectious Diseases and Clinical Immunology lstanbul Medical Facultylstanbul University Department of Pediatric Neurology lstanbul Medical Facultylstanbul University Department of Medical Genetics lstanbul Medical Facultylstanbul University

Background:Ataxia telangiectasia (AT) is a genetically based multisystemic *** aimed to make a comprehensive evaluation of multisystem involvement in AT by describing clinical features and outcome of 91 ***:Medical records of the patients who were diagnosed and followed by a multidisciplinary approach during a 27-year period (1988-2015) were reviewed ***:Forty six female and 45 male patients with a mean follow-up period of 39.13±4.28 months were *** mean age at the time of symptom onset and diagnosis were 15.4±1.09 months and 73.6144.11 months,*** abnormalities were progressive truncal ataxia,nystagmus,dysarthria,oculomotor apraxia and *** one patients (34.1%) became dependent on wheelchair at a mean age of 12.1±2.8 *** patients (12.1%) became bedridden by a mean age of 14.7±1.8 *** magnetic resonance imaging revealed pathological findings in 47/66 *** immunological parameters were determined in 51/91 patients:immunoglobulin (Ig)A deficiency (n=38),lymphopenia (n=30),IgG (n=15) and IgG2 (n=11) *** of recurrent sinopulmonary infections (n=45) and bronchiectasis (n=22) were found to be more common in patients with impaired immunological parameters (P=0.029and P=0.023,respectively).Malignancy developed in 5 patients,being mostly lymphoreticular in origin and resulted in death of 4 ***:AT is a long lasting disease with muitisystem involvement necessitating multidisciplinary follow up,as described in our *** diagnosis of malignancy and supportive treatments regarding pulmonary and neurological health may prolong survival and increase the quality of life.

关键词： ataxia telangiectasia immunodeficiency malignancies neurological impairment

Solid amine sorbents for CO_(2) capture by chemical adsorption: A review

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Petroleum 2017年第1期3卷 37-50页

作者： Elif ErdalÜnveren Bahar ozmen Monkul S¸erife Sarıoglan Nesrin Karademir Erdogan Alper Institute of Chemical Technology TUBITAK Marmara Research CenterGebze 41470KocaeliTurkey Chemical Engineering Department Hacettepe UniversityBeytepe 06800AnkaraTurkey

Amines are well-known for their reversible reactions with CO_(2),which make them ideal for CO_(2) capture from several gas streams,including flue *** this respect,selective CO_(2) absorption by aqueous alkanolamines is the most mature technology but the process is energy intensive and has also corrosion *** disadvantages can be diminished to a certain extent by chemical adsorption of CO_(2) *** most important element of the chemical adsorption of CO_(2) involves the design and development of a suitable adsorbent which consist of a porous support onto which an amine is attached or *** an adsorbent is often called as solid amine *** review covers solid amine-based studies which are developed and published in recent ***,the review examines several different types of porous support materials,namely,three mesoporous silica(MCM-41,SBA-15 and KIT-6)and two polymeric supports(PMMA and PS)for CO_(2) *** is given to the synthesis,modifications and characterizations-such as BET and PXRD data-of *** of these supports to obtain a solid amine sorbent through impregnation or grafting is reviewed *** is given to the adsorption mechanisms,material characteristics,and synthesis methods which are discussed in *** amount of original data are also presented which makes this review ***,relevant CO_(2) adsorption(or equilibrium)capacity data,and cyclic adsorption/desorption performance and stability of important classes of solid amine sorbents are critically *** include severa PEI or TEPA impregnated adsorbents and APTES-grafted systems.

关键词： Amine-impregnation Amine-grafting CO_(2)capture Chemical adsorption Mesoporous silica Solid amine sorbent Polymeric support Temperature swing adsorption