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Chinese Journal of Aeronautics 2018年第3期31卷 534-545页

作者： Marcio Augusto da silva SOUZA Weigang LI Reinaldo Crispiniano GARCIA Trans Lab Department of Computer Science University of Brasilia Department of Production Engineering University of Brasilia

The problem of capacity shortage in some airports needs to be dealt with sustainable solutions including a more efficient use of the existing runway slots at the airports. The Collaborative Decision Making（CDM） is an important approach applied to Air Traffic Management（ATM）to achieve this efficient use of the slots allocation. Using the Matching approach for two-sided markets of Game theory, the Top Trading Cycle CDM（TTC-CDM） algorithm developed in this research is an extension of the CDM approach aggregating the Ground Delay Program（GDP）of the air sector. The paper compared the developed TTC-CDM model to the existing models such as the conventional Compression algorithm in CDM, the Trade Cycle algorithm and the Deferred Acceptance CDM（da-CDM） model to evaluate the performance of the proposed model. Through a case study, the results show the effective application of TTC-CDM model to slot allocation in ATM and also presents the advantage of considering the preferences of airport managers beside ATC controllers and airlines in the decision processing.

关键词： Air traffic management Collaborative decision making Deferred acceptance Game theory Top trading cycles

The role of pro-inflammatory components, carcinoma-associated fibroblasts, and tumorassociated macrophages in ovarian cancer progression and metastasis

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Journal of Cancer Metastasis and Treatment 2023年第1期9卷 385-398页

作者： Josiany Carlos de Souza roberto silva Ribeiro Junior Tatiana Massariol Pimenta Bárbara da silva Martins Leticia Batista Azevedo Rangel Postgraduate Program in Biotechnology/RENORBIO Health Sciences CenterFederal University of Espirito SantoVitória 29047-105Brazil Department of Pharmaceutical Sciences Health Sciences CenterFederal University of Espirito SantoVitória 29047-105Brazil Biochemistry Program Health Sciences CenterFederal University of Espirito SantoVitória 29047-105Brazil

Ovarian cancer(OC)is associated with poor outcomes and challenges scientists and *** is usually diagnosed in advanced stages when it is frequently aggressive,chemoresistant,and *** most prevalent form of OC is epithelial ovarian cancer(EOC),which displays significant heterogeneity,enhancing the difficulty in managing the *** factors have been associated with the disease’s development and progression,especially those related to the tumor microenvironment(TME).Here,we highlight components of the ovarian TME in the disease development process,including pro-inflammatory pathways activated by interleukins,cytokines and chemokines,cancer-associated fibroblasts,tumor-associated macrophages,and epithelial-mesenchymal *** compiled evidence identifying TME factors promoting the development,chemoresistance,and metastasis,including cytokines,chemokines,growth factors,and tumor-associated *** identify potential targets for treatment and improving *** targets block or alter pathways associated with OC(especially EOC)progression.

关键词： CAFs interleukins ovarian cancer TAMs tumor microenvironment

Performance of masonry enclosure walls:lessons learned from recent earthquakes

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Earthquake Engineering and Engineering Vibration 2012年第1期11卷 23-34页

作者： Romeu silva Vicente Hugo Rodrigues Humberto Varum Aníbal Costa Jos António Raimundo Mendes da silva University of Aveiro Civil Engineering Department Campus Universitario de SantiagoAveiroPT3810-193Portugal University of Coimbra Civil Engineering Pinhal de MarrocosPolo ⅡCoimbraPT3030Portugal

This paper discusses the issue of performance requirements and construction criteria for masonry enclosure and infill walls. Vertical building enclosures in European countries are very often constituted by non-load-bearing masonry walls, using horizontally perforated clay bricks. These walls are generally supported and confined by a reinforced concrete frame structure of columns and beams/slabs. Since these walls are commonly considered to be nonstructural elements and their influence on the structural response is ignored, their consideration in the design of structures as well as their connection to the adjacent structural elements is frequently negligent or insufficiently detailed. As a consequence, nonstructural elements, as for wall enclosures, are relatively sensitive to drift and acceleration demands when buildings are subjected to seismic actions. Many international standards and technical documents stress the need for design acceptability criteria for nonstructural elements, however they do not specifically indicate how to prevent collapse and severe cracking, and how to enhance the overall stability in the case of moderate to high seismic loading. Furthermore, a review of appropriate measures to improve enclosure wall performance and both in-plane and out-of-plane integrity under seismic actions is addressed.

关键词： RC structures masonry enclosure walls infill walls in-plane out-of-plane cracking performanceimprovement

Coconut oil:what do we really know about it so far?

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Food Quality and Safety 2019年第2期3卷 61-72页

作者： Renan da silva Lima Jane Mara Block Department of Food Science and Technology Federal University of Santa CatarinaFlorianópolisBrazil

In recent years,coconut oil has emerged as a potential‘miracle’*** media vehicles and health specialists assure that this fat is capable of promoting health benefits,such as weight reduction,cholesterol lowering,prevention of cardiovascular diseases,and anti-inflammatory effect,among *** claims are used to market the product and boost its sales by coconut oil ***,governmental regulatory agencies in many countries are still sceptical about the benefits obtained by the consumption of coconut oil due to its high-saturated fatty acid *** light of such controversy,this review focused on analysing the published literature on the alleged health claims,in order to investigate if there is enough scientific evidence to support *** was verified that the metabolism of lauric acid,the major fatty acid in coconut oil,remains *** studies reported that the product was not efficient in weight ***,it has been reported that the consumption of coconut oil increased low-density lipoprotein cholesterol,consequently increasing the risk of cardiovascular *** general,the studies present conflicting results and there is a lack of long-term human-based clinical ***,as a saturated fat,coconut oil should be consumed with moderation and the health allegations should not be used to market the product,once they are not scientifically proven so far.

关键词： lauric acid saturated fatty acids medium-chain triglycerides LDL cholesterol cardiovascular diseases

Turbulent Inlet Conditions Modeling using Large-eddy Simulations

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Computer Modeling in Engineering & Sciences 2015年第2期104卷 105-132页

作者： M.M.R.damasceno J.M.Vedovoto A.da Silveira-neto UFU UberlandiaMGBrazil

Turbulence is a phenomenon which presents peculiarities when it is experimented or *** occurs due to its complexity and high sensibility to the inlet conditions of the turbulent flow fields,as well as the presence of a large range of time and length scales.A simplification for this situation is obtained with the use of approximations and turbulence *** the present work,the Largeeddy Simulations methodology was applied,aiming the modeling of the previously mentioned complexity,which consists in using a filter to resolve the large scales while the remaining scales were determined by classical and dynamic Smagorinsky *** different approximations for the inlet conditions were applied:white noise,Random Flow Generation(RFG)and Synthetic Eddy Method(SEM).It was possible to realize that the use of the dynamic Smagorinky model and the RFG or SEM methodologies resulted in a better characterization of the studied flow.

关键词： turbulent inlet conditions turbulence models large-eddy simulations

Ni/Carbon Hybrid Prepared by Hydrothermal Carbonization and Thermal Treatment as Support for PtRu Nanoparticles for Direct Methanol Fuel Cell

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Journal of Materials Science & Technology 2013年第8期29卷 747-751页

作者： Marcelo Marques Tusi Michele Brandalise Nataly Soares de Oliveira Polanco Olandir Vercino Correa Antonio Carlos da silva Juan Carlo Villalba Fauze Jaco Anaissi Almir Oliveira neto Estevam Vitorio Spinac Universidade Regional Integrada do Alto Uruguai e das Missoes-URI Av.Batista Bonoto Sobrinhos/nSao Vicente97700-000 SantiagoRSBrazil Instituto de Pesquisas Energticas e Nucleares-IPEN/CNEN-SP Av.Prof.Lineu Prestes2242Cidade Universitria05508-900 Sao PauloSPBrazil Universidade Estadual do Centro-Oeste-UNICENTRO R.Simeao Varela de S 03Vila Carli85040-080 GuarapuavaPRBrazil

Ni/Carbon was prepared in two steps： initially cellulose as carbon source and NiCl2·6H2O as catalyst of the carbonization process were submitted to hydrothermal treatment at 200 ℃ and further to thermal treatment at 900 ℃ under argon atmosphere. The obtained material contains Ni nanoparticles with face-centered cubic （fcc） structure dispersed on amorphous carbon with graphitic domains. PtRu/C electrocatalysts （carbon- supported PtRu nanoparticles） were prepared by an alcohol-reduction process using Ni/Carbon as support. The materials were characterized by thermogravimetric analysis, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy and tested as anodes in single direct methanol fuel cell （DMFC）. The performances of PtRu/C electrocatalysts using Ni/Carbon as support were superior to those obtained for PtRu/C using commercial carbon black Vulcan XC72 as support.

关键词： Cellulose Hydrothermal carbonization Alcohol-reduction process PtRu/C electrocatalysts Direct methanol fuel cell

A Finite Element Study of the Influence of Graphite Nodule Characteristics on a Subsurface Crack in a Ductile Cast Iron Matrix under a Contact Load

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Computer Modeling in Engineering & Sciences 2018年第10期117卷 59-71页

作者： Guilherme Suguinoshita Carlos Henrique da silva Marco Antonio Luersen Department of Mechanical Engineering Federal University of Technology-Parana(UTFPR)Rua Deputado Heitor Alencar Furtado5000CEP 81280-340CuritibaBrazil

This paper describes a study of the effects of graphite nodule characteristics on a subsurface crack in austempered ductile iron(ADI).A representative specimen of ADI,subjected to sliding contact load,is modeled using finite elements aiming to obtain the shear stress intensity factor(KII).The parameters varied were(i)the nodule diameter(two different values were considered),(ii)the distance between the nodule and the tip of the crack and(iii)the position of the load relative to the tip of the *** results of the numerical simulations show that the smaller diameter nodule has a larger influence on KII,suggesting a higher contact fatigue crack propagation rate in the material with the smaller *** results are the opposite of those observed in experimental studies and would appear to indicate that other factors should be also considered to ensure realistic estimates of the contact fatigue strength of ADI.

关键词： Austempered ductile iron subsurface crack stress intensity factor finite element analysis graphite nodule

Mapping of the Brazilian Groups Studying Nanocellulose

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Journal of Renewable Materials 2019年第5期7卷 429-440页

作者： Asaph Armando Jacinto Márcia Aparecida da silva Spinacé Center of Natural and Human Sciences Federal University of ABCSanto AndréSPBrazil

The nanocellulose is a material that has gained much attention in the recent ***,the relevance of Brazil in this field was evaluated concerning the scientific publications in Web of ***,the Brazilian groups were mapped using a bibliometric procedure on these ***,more factors were analyzed from them *** were the sources to extract the nanocellulose in Brazil,the methods to do it,the characterizations to determine its dimensions and the funding agencies of these *** results identified 69 Brazilian ***,the bacterial cellulose was the most common *** the acid hydrolysis was the most used *** its turn,the size characterization was mostly by scanning electron *** last,the most important agencies were the CNPq,the CAPES and the *** these points,it was possible to suggest the opportunities to develop the nanocellulose research in Brazil.

关键词： Nanocellulose bibliometry scientometrics scientific publication web of science

Natural enemies depend on remnant habitat size in agricultural landscapes

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Journal of Forestry Research 2015年第2期26卷 469-477页

作者： Mainara Xavier Jordani erica Hasui Vinicius Xavier da silva Laboratorio de Ecologia Animal Departamento de Zoologia e BotanicaUniversidade Estadual Paulista-UNESPRua Cristovao Colombo2265Jardim NazarethSao Jose Do Rio PretoSP CEP 15054-000Brazil Laboratorio de Ecologia de Fragmentos do Sul de Minas Gerais-ECOFRAG Instituto Ciencias da NaturezaUniversidade Federal de Alfenas-UNIFAL–MGRua Gabriel Monteiro da Silva700CentroAlfenasMG CEP 37130-000Brazil

In recent decades,the consequences of habitat fragmentation have been of growing concern,because it is particularly important to understand how fragmentation may affect biodiversity,an ecological *** tested two hypotheses：（1） that natural fragment size in agricultural landscapes indirectly affects the herbivore through effects on natural predator populations;and（2） predator activity into the crop reduces along the distance from the natural fragment *** 2008 and 2009,we conducted our study in seven forest remnants and in surrounding coffee plantations（fragments ranged from 6 to 105 ha,mean 49.28 ± 36.60 ha） in Southern Minas Gerais,*** were sampled by point counts,and insect predation was evaluated by using an artificial insect model（Koh and Menge 2006）.Our results suggest that although there were many potential predators（e.g.,wasps,ants,birds,and mammals）,birds were the most important taxon *** covariance analysis supported the hypothesis that patch size affected the number of larvae predation by overall taxi,but there was no support for a distance *** findings suggest that natural enemies’ ecological service（mainly from birds） declined with remnant reduction,which has implications not only for human welfare,but also in strengthening the economic justifications for conserving the remaining natural habitats and biodiversity in agricultural landscapes.

关键词： Ecosystem service Fragmentation Isolation Insectivore Predation

Yet Another Intelligent Code-Generating System： A Flexible and Low-Cost Solution

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Journal of Computer Science & Technology 2018年第5期33卷 940-965页

作者： Joao Fabricio Filho Luis Gustavo Araujo Rodriguez Anderson Faustino da silva Department of Informatics State University of Maringd Maringd-PR 87020-900 Brazil Federal University of Technology -- Parand Campo Mourao-PR 87301-899 Brazil

Modern compilers apply various code transformation algorithms to improve the quality of the target code. However, a complex problem is to determine which transformation algorithms must be utilized. This is difficult because of three reasons： a number of transformation algorithms, various combination possibilities, and several configuration possibil- ities. Over the last few years, various intelligent systems were presented in the literature. The goal of these systems is to search for transformation algorithms and thus apply them to a certain program. This paper proposes a flexible, low-cost and intelligent system capable of identifying transformation algorithms for an input program, considering the program＇s specific features. This system is flexible for parameterization selection and has a low-computational cost. In addition, it has the capability to maximize the exploration of available computational resources. The system was implemented under the Low Level Virtual Machine infrastructure and the results indicate that it is capable of exceeding, up to 21.36%, performance reached by other systems. In addition, it achieved an average improvement of up to 17.72% over the most aggressive compiler optimization level of the Low Level Virtual Machine infrastructure.

关键词： compiler code transformation iterative compilation knowledge representation machine learning