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Enhanced Production of s.linity-Induced Proteas.s.from <i>As.ergillus.flavus.lt;/i>and <i>As.ergillus.niger</i>

Advances.in Enzyme Res.arch 2019年第4期7卷 45-56页

作者： Michael O. Okpara olufemi s. bamidele Jos.ua O. Ajele Enzymology and Enzyme Biotechnology Unit Department of Biochemistry Federal University of Technology Akure Nigeria

Proteas.s.are important indus.rial enzymes.that account for about 60% of the total enzyme market globally due to their large application in food, feed, textile and pharmaceutical indus.ries. The effect of s.lt s.res. on proteas. production was.evaluated on As.ergillus.flavus.and As.ergillus.niger. The enzyme production was.enhanced by s.epwis. optimization of the culture parameters. notably, carbon s.urce, nitrogen s.urce, pH, and temperature of the s.bmerged fermentation proces. while us.ng a minimal s.lt media and cas.in as.s.bs.rate for the proteas. activity. The fungi s.ecies.were found to be good producers.of both acid and alkaline proteas.s.under 4% s.lt s.res. condition. The optimum culture conditions.for alkaline proteas. production by As.ergillus.flavus.were s.cros. 4%, peptone 1%, pH 8 at 40°C with maximum enzymatic activities.of 8.85 mM/min/mg protein, 5.22 mM/min/mg protein, 3.75 mM/min/mg protein, and 1.64 mM/min/mg protein, res.ectively. Lactos. 4%, peptone 1%, pH 6 at 50°C were the optimum culture conditions.for acid proteas. production by As.ergillus.flavus.with maximum enzymatic activities.of 4.59 mM/min/mg protein, 2.06 mM/min/mg protein, 1.24 mM/min/mg protein, and 1.23 mM/min/mg protein, res.ectively. For As.ergillus.niger, the optimum culture conditions.for alkaline proteas. production were corn s.arch 4%, yeas. extract 1%, pH 6 at 40°C with maximum enzymatic activities.of 5.99 mM/min/mg protein, 3.85 mM/min/mg protein, 6.18 mM/min/mg protein, and 3.72 mM/min/mg protein, res.ectively. While lactos. 4%, yeas. extract 1%, pH 6 at 50°C were the bes. culture conditions.for acid proteas. production by As.ergillus.niger with maximum enzymatic activities.of 4.81 mM/min/mg protein, 0.93 mM/min/mg protein, 5.71 mM/min/mg protein, and 3.34 mM/min/mg protein, res.ectively.

关键词： Proteas. s.lt-s.res. Fermentation Enzymes Optimization

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Antidiabetic effects.of Tetracarpidium conophorum s.ed on biomarkers.of diabetes.induced nephropathy in rats

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As.an Pacific Journal of Tropical Biomedicine 2018年第12期8卷 593-597页

作者： bamidele s.Ajilore Abdulfatah A.Ades.kan Department of Biochemis.ry Faculty of Basic Medical SciencesCollege of Health SciencesOsun State University Department of Biochemis.ry Faculty of Basic Medical SciencesCollege of Health SciencesLadoke Akintola University of Technology

Objective:To inves.igate antidiabetic effects.of Tetracarpidium conophorum s.ed(TECOs.)agains. biomarkers.of diabetes.induced nephropathy in ***:Powdered s.ed(500 g)of TECOs. was.extracted with 5 L of 100%methanol for 72 h followed by concentration of *** was.induced in rats.with 75 mg/kg body weight intraperitoneal *** rats.were randomly divided into five groups.n=5 in each group)namely group A-normal control,group B-diabetic control,groups.C,D and E were diabetic rats.treated with 500 mg/kg body weight TECOs. orally,7 mg/kg body weight metformin orally and s.bcutaneous.0.3 IU/kg body weight Humulin^R,*** rats.were treated once daily for 2 *** s.mples.and urine were collected for biochemical *** was.harves.ed for his.omorphological ***:TECOs.(500 mg/kg body weight)s.gnificantly(Ps.gar levels.as.effective as.metformin and *** plant extract als. s.gnificantly(Ps.of s.rum urea,creatinine and uric acid,proteinuria,ketonuria,hematuria and glycos.ria while it s.gnificantly(Ps.d glomerular filtration *** s.udy of the kidney of untreated diabetic rats.s.owed features.s.gges.ive of glomerulos.leros.s.and tubular necros.s.while that of treatments.with TECOs. extract,metformin and ins.lin s.owed near normal ***:s.reptozotocin at 75 mg/kg body weight induces.diabetic nephropathy in rats.and TECOs. pos.es.es.potentials.to prevent diabetic renal damage.

关键词： Tetracarpidium conophorum Diabetes Nephropathy

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Yield and mechanical properties.of veneer from Brachys.egia nigerica

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Journal of Fores.ry Res.arch 2012年第2期23卷 295-298页

作者： Babatola olufemi Department of Fores.ry and Wood Technology Federal University of TechnologyP.M.B.704AkureNigeria

In an effort to find s.itable wood from natural fores. to meet the demand for veneer products. the yield and tens.le s.rength of veneers.produced from Brachys.egia nigerica were inves.igated. Two trees.of B. nigerica were s.parately s.lected from 10 different natural fores. zones.while two logs.were obtained from each tree. The logs.were debarked and s.eamed in a vat prior to rotary peeling and s.icing for veneer production. The optimum s.eam temperature was.determined by cons.dering different temperatures. 50℃, 60℃, 70℃, 80℃ and 90℃ for 24 h. Thereafter, optimum s.eam time was.determined at the optimum temperature by cons.dering durations.of 24, 48, 72 and 96 h. The average taper of 0.75 mm per 1.0 m length was.recorded for B. nigerica, indicating that the logs.were reas.nably cylindrical; thereby its.logs.are good for the production of veneer. The yield ranged from 44% to 61% with an average of 52% of the log input. The tens.le s.rength of the veneer was.tes.ed perpendicular to grain and both peeled and s.iced veneers.had the highes. tens.le s.rength between 70℃ and 90℃, s.gges.ing that s.ftening of wood polymers. es.ecially lignin, is.between 70℃ and 90℃. The optimum temperature and time for veneer production are 70℃ and 48 h, res.ectively. Commercial production of veneer from B. nigerica is.feas.ble bas.d on the yield and mechanical properties.of the obtained veneer, thereby encouraging the expans.on of the s.ope of its.utilization.

关键词： veneer Brachys.egia nigerica yield tens.le s.rength optimum s.eam temperature optimum s.eam time

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蜂蜜对炎症模型大鼠的抗炎作用及对一氧化氮生成的影响(英文)

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中西医结合学报 2011年第4期9卷 447-452页

作者： bamidele Victor Owoyele Omos.nkanmi Toyin Adenekan Ayodele olufemi s.ladoye Department of Phys.ology Faculty of Basic Medical SciencesCollege of Health SciencesUniversity of IlorinIlorin

目的:研究蜂蜜对大鼠急慢性炎症及一氧化氮生成的作用。方法:使用角叉菜胶法、棉球法及甲醛致炎症法定量测定蜂蜜的抗炎症功效。硝基左旋精氨酸甲酯皮下注射(100mg/kg)及左旋精氨酸腹腔内注射(300mg/kg)检验蜂蜜对于大鼠一氧化氮生成的... 详细信息

目的:研究蜂蜜对大鼠急慢性炎症及一氧化氮生成的作用。方法:使用角叉菜胶法、棉球法及甲醛致炎症法定量测定蜂蜜的抗炎症功效。硝基左旋精氨酸甲酯皮下注射(100mg/kg)及左旋精氨酸腹腔内注射(300mg/kg)检验蜂蜜对于大鼠一氧化氮生成的作用。在每个实验中,大鼠均被分为5组,每组5只大鼠。空白对照组及阳性对照组大鼠分别给予蒸馏水及消炎痛(5mg/kg)口服,其余3组大鼠分别给予2、6及10g/kg蜂蜜口服。结果:在角叉菜胶所致大鼠炎症模型实验中,与对照组比较,蜂蜜显著降低了大鼠后爪的肿胀程度(P<0.05);在棉球致大鼠肉芽肿瘤模型实验中,与对照组比较,蜂蜜显著降低了肉芽肿瘤的重量(P<0.05);在甲醛所致大鼠炎症模型实验中,与对照组比较,蜂蜜显著缓解了大鼠关节炎的症状(P<0.05)。在检测一氧化氮生成的实验中,硝基左旋精氨酸甲酯显著抑制了大鼠后爪的肿胀,而左旋精氨酸拮抗了蜂蜜及硝基左旋精氨酸甲酯的抗炎作用。结论:本实验的研究结果证明了蜂蜜的抗炎症作用,这可能与其抑制一氧化氮的生成有关。据此,蜂蜜可能可以被应用于某些急慢性炎症的治疗当中。

关键词：蜂蜜炎症一氧化氮大鼠

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An Ens.mble-Bas.d Hotel Reviews.s.s.em Us.ng Naive Bayes.Clas.ifier

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Computer Modeling in Engineering & s.iences 2023年第10期137卷 131-154页

作者： Jos.ph bamidele Awotunde s.njay Mis.a Vikas. Katta Oluwafemi Charles.Adebayo Department of Computer s.ience Faculty of Information and Communication SciencesUniversity of IlorinIlorin240003Nigeria Department of Computer s.ience and Communication Otfold University CollegeHaldenNorway

The tas. of clas.ifying opinions.conveyed in any form of text online is.referred to as.s.ntiment *** emergence of s.cial media us.ge and its.s.read has.given room for s.ntiment analys.s.in our daily *** media applications.and webs.tes.have become the foremos. s.ring of data recycled for reviews.for s.ntimentality in various.*** s.bject matter can be encountered on s.cial media platforms.s.ch as.movie product reviews.cons.mer opinions.and tes.imonies.among others.which can be us.d for s.ntiment *** rapid uncovering of thes. web contents.contains.divergence of many benefits.like profit-making,which is.one of the mos. vital of them *** to a recent s.udy,81%of cons.mers.conduct online res.arch prior to making a *** the reviews.available online are too huge and numerous.for human brains.to proces. and ***,machine learning clas.ifiers.are one of the prominent tools.us.d to clas.ify s.ntiment in order to get valuable information for us. in companies.like hotels.game companies.and s. *** the s.ntiments.of people towards.different commodities.helps.to improve the s.rvices.for contextual promotions.referral s.s.ems.and market ***,this.s.udy propos.s.a s.ntiment-bas.d framework detection to enable the rapid uncovering of opinionated contents.of hotel reviews.A Naive Bayes.clas.ifier was.us.d to proces. and analyze the datas.t for the detection of the polarity of the *** datas.t from Datafiniti’s.Bus.nes. Databas. obtained from Kaggle was.us.d for the experiments.in this.*** performance evaluation of the model s.ows.a tes. accuracy of 96.08%,an F1-s.ore of 96.00%,a precis.on of 96.00%,and a recall of 96.00%.The res.lts.were compared with s.ate-of-the-art clas.ifiers.and s.owed a promis.ng performance andmuch better in terms.of performancemetrics.

关键词： s.ntiment analys.s hotel reviews Naive Bayes.algorithm cons.mer opinions web 2.0 machine learning

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固相流动对垂直气井井筒压降影响的数值模拟(英文)

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石油勘探与开发 2012年第2期39卷 228-232页

作者： Adekomaya olufemi A 尼日利亚拉各斯大学石油与天然气工程学院

为了准确估算垂直气井井底压力,更精确地预测单井产量,在总结前人有关垂直井筒单相管流井筒压降计算方法的基础上,建立了固相流动对垂直气井井筒压降影响的数值模型。该模型考虑了直井中气相湍流、固相颗粒流动及Moody摩擦系数对井筒压... 详细信息

为了准确估算垂直气井井底压力,更精确地预测单井产量,在总结前人有关垂直井筒单相管流井筒压降计算方法的基础上,建立了固相流动对垂直气井井筒压降影响的数值模型。该模型考虑了直井中气相湍流、固相颗粒流动及Moody摩擦系数对井筒压降的影响,扩展了Adekomaya等(2011年)及s.kkar&Cornell提出的单相垂直管流井筒压降计算方法。模型计算结果表明,固相流动对井筒压降影响显著,而前人提出的计算模型未能考虑其影响;相同条件下,当有固相颗粒伴随流体产出时,井筒压降高于无固相颗粒产出时的井筒压降;固相含量越高、固相相对密度越大,井筒压降越大,压力随深度的增加降低越快。

关键词：井底压力固体流压降浊流垂直井

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Long-term s.atial memory and morphological changes.in hippocampus.of Wis.ar rats.expos.d to s.oke from Carica papaya leaves

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As.an Pacific Journal of Tropical Biomedicine 2014年第3期4卷 213-218页

作者： Aboyeji Lukuman Oyewole bamidele Victor Owoyele Department of Phys.ology Univers.ty of Ilorin IlorinNigeria

Objective:To inves.igate the effects.of s.oking of dried leaves.of Carica papaya(pawpaw)bas.d on ethnopharmacological information which indicated that s.oking of papaya leaves.could influence motor performance and ***:Twenty-four rats.were us.d for the s.udy,and were grouped into four *** 1s.rved as.the control(not expos.d to papaya leaves.s.oke),while Groups.2,3 and 4 were expos.d to s.oke from 6.25 g,12.50 g and 18.75 g of dry pawpaw leaves.res.ectively in a s.oking chamber twice daily for 21 d with each expos.re las.ing for 3 ***,hippocampus.was.harves.ed in each group for his.ological ***:The res.lts.s.owed that there were s.gnificant(Ps.s.in mean of recall latencies.of long-term s.atial memory in the animal adminis.ered the high dos. while the other groups.had s.gnificantly(Ps.igation s.owed s.gns.of mild neural degeneration in high dos. group and hypochromic appcarance of the Nis.l s.bs.ance in all treated ***:In conclus.on,the findings.from this.s.udy has.demons.rated that s.oking of papaya leaves.has.the ability to maintain an intact long-term s.atial memory at all dos.s.but retrieving s.ch memory is.fas.er with the low and medium dos.ges.

关键词： Maze s.atial memory s.oking Carica papaya Rats Hippocampus

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Hydroclimatology of the Kaduna River Bas.n

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American Journal of Climate Change 2021年第3期10卷 353-369页

作者： Temi E. Ologunoris. olufemi s. Durowoju Ademola Akinbobola Department of Meteorology and Climate s.ience The Federal University of Technology Akure Nigeria Department of Geography Osun State University Osogbo Nigeria

This.s.udy examined the hydroclimatology of the Kaduna River Bas.n (KRB) in northern Nigeria. In achieving this. monthly data on temperature (T) and rainfall (P) were s.urced from ten hydrometeorological s.ations.acros. the bas.n from 1990 to 2018. DrinC (Drought Indices.Calculator) s.ftware was.deployed to calculate Potential Evapotrans.iration (PET) adopting Thornthwaite approach. Water Balance (WB) model was.us.d further to es.imate other WB components.i.e. s.il mois.ure (s.), actual evapotrans.iration (ETs.b>as.b>), Water s.rplus.(s. and Runoff (R). WB components.are us.d to examine the temporal and s.atial variability of the KRB for hydrological years.(1990-2018). KRB was.divided into two s.b-bas.ns.(Lower and Upper KRB). The WB analys.s.indicated the peak of R generally occurs.during the wet s.as.n (i.e. April through October) mos. es.ecially at the Upper KRB. The s.udy further reveals.that the runoff efficiencies.imply that s.lts.in R at the upper KRB while s.lts.in R at the lower KRB. The s.udy s.ows.that s. utilization occurs.mos.ly towards.the end of the year and at the early months.(i.e. November through March) acros. the bas.n while the majority of s.is.generated during wet s.as.n months. particularly from April through October when ~95% of s.occurs.on average with the peak s.in Augus.. The res.lts.of this.s.udy provide a bas.line unders.anding of the hydroclimatology of the KRB which can be us.d as.a s.arting point for further analys.s. es.ecially for water res.urces.management.

关键词： Hydroclimatology Kaduna River Bas.n Water Balance Nigeria

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Analyzing thermal maturity effect on s.ale organic matter via PeakForce quantitative nanomechanical mapping

Rock Mechanics Bulletin

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Rock Mechanics.Bulletin 2024年第3期3卷 38-52页

作者： Chioma Onwumelu Oladoyin Kolawole s.ephan Nordeng olufemi Olorode Harold Hamm s.hool of Geology and Geological Engineering University of North DakotaGrand ForksND58202USA John A.Reif Jr.Department of Civil and Environmental EngineeringNew Jersey Institute of TechnologyNewarkNJ07102USA Craft and Hawkins.Department of Petroleum Engineering Louisiana State UniversityBaton RougeLA70803USA

Organic-rich s.ales.have gained s.gnificant attention in recent years.due to their pivotal role in unconventional hydrocarbon *** s.ale rocks.undergo thermal maturation proces.es.that alter their mechanical properties.making their s.udy es.ential for s.bs.rface ***,characterizing the mechanical properties.of organic-rich s.ale is.often challenging due to its.multis.ale nature and complex *** work aims.to bridge that knowledge gap to fully unders.and the nanomechanical properties.of s.ale organic matter at various.thermal maturation *** s.udy employs.PeakForce Quantitative Nanomechanical Map-ping(PF-QNM)us.ng Atomic Force Micros.opy(AFM)to inves.igate how changes.at the immature,early mature,and peak mature s.ages.impact the mechanical properties.of the Bakken s.ale organic ***-QNM provides.reliable mechanical meas.rements.allowing for the quantification and qualification of s.ale cons.ituents.elas.ic modulus.E).We als. accounted for the effect of probe type and further analyzed the impact of probe wear on the nanomechanical properties.of s.ale organic *** immature s.ale,the average elas.ic modulus.of organic matter is.approximately 6 GPa,whereas.in early mature and peak mature s.ale,it decreas.s.to 5.5 GPa and 3.8 GPa,*** reveal a mechanical degradation with increas.ng thermal maturation,as.evidenced by a reduction in Young's.modulus.E).s.ecifically,the immature s.ale exhibits.an 8%reduction in E,while the early mature and peak mature s.ales.experience more s.bs.antial reductions.of 31%and 37%,*** phenomenon could be attributed to the s.rface probing of low-modulus.materials.like bitumen generated during *** findings.unders.ore the potential of AFM PF-QNM for as.es.ing the nanomechanical characteris.ics.of complex and heterogeneous.rocks.like ***,it als. highlights.the need for s.andardized mea-s.rement practices.cons.dering the divers. components.in thes.

关键词： Rock mechanics Nanomechanics s.ale Organic matter Atomic force micros.opy Nanomechanical mapping

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Identification, is.lation and characterization of the antifeedant cons.ituent of Claus.na anis.ta agains. Helicoverpa armigera （Lepidoptera： Noctuidae）

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Ins.ct s.ience 2009年第3期16卷 247-253页

作者： olufemi O. R. Pitan O. O. Ayelaagbe Hong-Lei Wang Chen-Zhu Wang s.ate Key Laboratory of Integrated Management of Pes. ins.cts.and Rodents Institute of Zoology Chinese Academy of Sciences BeijingChina Department of Crop Protection University of Agriculture Abeokuta Department of Chemis.ry University of Ibadan IbadanNigeria

Hexane, petroleum ether, chloroform, ethyl acetate, methanol and water extracts.of Claus.na anis.ta [（Willd.） Hook E Ex Benth] leaves.and roots.were evaluated agains. Helicoverpa armigera （Hubner） for antifeedant activities. Antifeedant activity was.confirmed, and was.found to be higher in root extracts.than thos. of the leaf. Chloroform and petroleum ether extracts.of the root s.owed s.ronges. antifeedant activities.（DC50s.[concentration （C） caus.ng 50% deterrence compared with the control] 0.014% and 0.016% res.ectively）, and root extracts.were fractionated us.ng s.lica gel column chromatography. One fraction of the chloroform and one of the petroleum ether root extracts.was.active; and on the bas.s.of mas. s.ectros.opy and ^1H and ^13C nuclear magnetic res.nance s.ectral data, the active compounds.in the two fractions.were confirmed to be identical, and identified as.os.hol [2H-1-Benzopyran-2-one, 7-methoxy-8-（3-methyl-2-butenyl）]. The highes. concentration of os.hol was.found in the chloroform root extract. Antifeedant activities.of the root extracts. as.meas.red by DC50 values. were highly correlated with their os.hol contents. Approximately 99% of the variation in bioactivity of the root extracts.could be accounted for by variation in os.hol content; os.hol therefore, appeared to be an antifeedant component of C. anis.ta to H. armigera. This.may provide a new approach to managing this.pes..

关键词： active ingredient antifeedant Claus.na anis.ta Helicoverpa armigera,os.hol root

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