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Medium-Term Results of Balloon Valvuloplasty of Native Pulmonary Valve Stenosis with and without Supravalvular Obstruction in Childhood

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Congenital Heart Disease 2022年第2期17卷 161-172页

作者： olivia lenoir Daniel Quandt Oliver Kretschmar Walter Knirsch Pediatric Cardiology Pediatric Heart CenterChildren’s Research CenterUniversity Children’s Hospital ZurichZurichSwitzerland University of Zurich ZurichSwitzerland

Objectives:Factors influencing results of balloon valvuloplasty(BVP)of pulmonary valve stenosis(PS)in children are ***:BVP has become the standard of care for PS,medium-term results are not uniform and depend on various ***:We analysed the medium-term results of BVP of PS in children in an observational,single centre *** for additional procedure was defined as outcome after initial ***:We included 143 children(83 female)at a median(IQR)age of 2.6(0.26–9.24)months and body weight of 5(3.4–8)kg at BVP with a follow–up of 5.04(1.6–10.2)*** used balloon size of 10(9–14)mm and maximal balloon pressure of 4(3.5–10)atm,resulting in balloon–to–pulmonary annulus ratio of 1.28(1.2–1.4).Systolic pressure gradient of PS was reduced with BVP(43.5 mmHg vs.14.0 mmHg,p<0.001)and confirmed by echocardiography(68.0 mmHg vs.25.0 mmHg,p<0.001)day 1 post *** BVP with associated supravalvular PS resulted in a relevant reduction of systolic pressure gradient in 23 of 31 patients(74.2%).Early additional procedure was necessary in 14 patients(9.8%)after 0.2(0.1–0.7)years due to residual PS(n=13)and infective endocarditis(n=1).Factors for additional procedures were associated supravalvular PS with a higher residual pressure gradient,but not genetic *** further follow–up of 5.04(1.6–10.2)years no further additional procedures were ***:Pulmonary BVP of native pulmonary valve stenosis leads to excellent medium-term results,even in 3 of 4 infants with associated supravalvular obstruction sufficient pressure relief can be obtained.

关键词： Pediatric catheter congenital pulmonary balloon valvuloplasty

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