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Energy shift： decline of easy oil and restructuring of eo-politics

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Frontiers in Energy 2016年第3期10卷 260-267页

作者： oliver R. INDERWILDI David A. KING Smith School of Enterprise and the Environment University of OxfordOxford OX1 3QY United Kingdom

This paper critically assesses the geopolitical and geo-economic impact of novel fuel resources on both resource exporters and importers. Presently, very strong political and economic forces drive the utilisation of domestic, unconventional oil and gas recovery in the West as these enhance energy security and ease balance of payment issues. The additional capacity generated by this trend has, supported by other effects such as Saudi Arabia＇s decision to maintain current production, triggered a significant reduction ofoil prices. Consequently, it is now oil exporters that struggle with the balance of payment issues and often these countries base their fiscal budget completely on fossil fuel revenues. In fact, these unconventional resources help turn the tide while oil exporters are now politically significantly weakened due to the increased energy sufficiency of the West. The catch is that the extraction of unconventional types ofoil has many environmental implications. So, internalising the environ- mental externalities have to be considered. This paper, therefore, assesses, next to geopolitics and geo-economics, the environmental implications of this trend.

关键词： energy security climatic change geo-economics geopolitics unconventional resources macroeconomics

Proposed framework for blockchain technology in a decentralised energy network

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Protection and Control of Modern Power Systems 2021年第1期6卷 396-406页

作者： oliver Dzobo Bessie Malila Lindokhuhle Sithole Department of Electrical&Electronic Engineering Science University of JohannesburgJohannesburgSouth Africa Department of Biomedical Engineering University of Cape TownCape TownSouth Africa

The integration of distributed renewable energy sources into the conventional power grid has become a hot research topic, all part of attempts to reduce greenhouse gas emission. There are many distributed renewable energy sources available and the network participants in energy delivery have also increased. This makes the management of the new power grid with integrated distributed renewable energy sources extremely complex. Applying the technical advantages of blockchain technology to this complex system to manage peer-to-peer energy sharing, transmission, data storage and build smart contracts between network participants can develop an optimal consensus mechanism within the new power grid. This paper proposes a new framework for the application of blockchain in a decentralised energy network. The microgrid is assumed to be private and managed by local prosumers. An overview description of the proposed model and a case study are presented in the paper.

关键词： Blockchain technology Distributed renewable energy sources Energy delivery Smart contract Distributed cloud storage system

How to derive a geovisualization from an application data model: an approach based on Semantic Web technologies

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International Journal of Digital Earth 2021年第7期14卷 874-898页

作者： Matthieu Viry Marlène Villanova-oliver Univ.Grenoble Alpes CNRSGrenoble INP(Institute of Engineering Univ.Grenoble Alpes)LIGGrenobleFrance

While ontological modelling and Semantic Web technologies are sometimes used to describe knowledge domains with a spatial component,there is still a lack of semantics to describe how to present this knowledge geovisually to the end user and how to automatize the *** this paper,we first present vocabularies to describe at a high level the elements that make up a *** then propose a method that describes at a semantic level how to obtain a geovisualization from an existing data *** method is based on our vocabularies and on a set of semantic rules encoding rich and complex operations on *** leads to the derivation of ontological knowledge,ready to be exploited to automate the creation of a *** method is implemented in a framework that uses Semantic Web *** singularity and the strength of our proposal is that it enables to describe a geovisualization through a RDF specification file,which once loaded in our system makes the geovisualization directly available for use from a Web *** result is obtained by extending a priori an application data model with ad hoc geovisualization semantics features and rules.

关键词： Knowledge representation Semantic Web geovisualization ontologies rule-based system

In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokines

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World Journal of Gastroenterology 2007年第22期13卷 3063-3070页

作者： Dennis Hoffmann Wibke Bayer oliver Wildner Department of Molecular and Medical Virology Institute of Microbiology and Hygiene Ruhr-University Bochum Bldg. MA Rm. 6/40 D-44801 Bochum Germany

AIM： To evaluate whether intratumoral expression of measles virus fusogenic membrane glycoproteins H and F （MV-FMG）, encoded by an adenovirus vector ***-HI F, alone or in combination with local coexpression of cytokines （IL-2, IL-12, IL-18, IL-21 or GM-CSF）, can serve as a platform for inducing tumor-specific immune responses in colon cancer.METHODS： We used confocal laser scanning microscopy and flow cytometry to analyze cell-cell fusion after expression of MV-FMG by dye colocalization. In a syngeneic bilateral subcutaneous MC38 and Colon26 colon cancer model in C57BL/6 and BALB/c mice, we assessed the effect on both the directly vector-treated tumor as well as the contralateral, not directly vector- treated tumor. We assessed the induction of a tumorspecific cytotoxic T lymphocyte （CTL） response with a lactate dehydrogenase （LDH） release assay.RESULTS： We demonstrated in vitro that transduction of MC38 and Colon26 cells with ***-H/F resulted in dye colocalization, indicative of cell-cell fusion, in addition, in the syngeneic bilateral tumor model we demonstrated a significant regression of the directly vector-inoculated tumor upon intratumoral expression of MV-FMG alone or in combination with the tested cytokines. We observed the highest anti-neoplastic efficacy with MV-FMG and lL-21 coexpression. The degree of tumor regression of the not directly vector-treated tumor correlated with the anti-neoplastic response of the directly vector-treated tumor. This regression was mediated by a tumor-specific CTL response.CONCLUSION： Our data indicate that intratumoral expression of measles virus fusogenic membrane glycoproteins is a promising tool both for direct tumor treatment as well as for tumor vaccination approaches that can be further enhanced by cytokine coexpression.

关键词： Adenovirus vectors Measles virus fusogenic membrane glycoproteins Colorectal cancer Interleukins

On Unsupervised Training of Multi-Class Regularized Least-Squares Classifiers

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Journal of Computer Science & Technology 2014年第1期29卷 90-104页

作者： Tapio Pahikkala Antti Airola Fabian Gieseke oliver Kramer ACM IEEE Department of Information Technology University of Turku Department of Computer Science University of Copenhagen Computer Science Department Carl von Ossietzky University of Oldenburg

In this work we present the first efficient algorithm for unsupervised training of multi-class regularized least- squares classifiers. The approach is closely related to the unsupervised extension of the support vector machine classifier known as maximum margin clustering, which recently has received considerable attention, though mostly considering the binary classification case. We present a combinatorial search scheme that combines steepest descent strategies with powerful meta-heuristics for avoiding bad local optima. The regularized least-squares based formulation of the problem allows us to use matrix algebraic optimization enabling constant time checks for the intermediate candidate solutions during the search. Our experimental evaluation indicates the potential of the novel method and demonstrates its superior clustering performance over a variety of competing methods on real world datasets. Both time complexity analysis and experimental comparisons show that the method can scale well to practical sized problems.

关键词： unsupervised learning multi-class regularized least-squares classification maximum margin clustering combinatorial optimization

Complementary and alternative medicines in irritable bowel syndrome: An integrative view

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World Journal of Gastroenterology 2014年第2期20卷 346-362页

作者： oliver Grundmann Saunjoo L Yoon Department of Medicinal Chemistry College of PharmacyUniversity of FloridaFL 32610United States Department of Adult and Elderly Nursing College of NursingUniversity of FloridaFL 32610United States

Irritable bowel syndrome(IBS)is a common gastrointestinal disorder with a high incidence in the general *** diagnosis of IBS is mainly based on exclusion of other intestinal conditions through the absence of inflammatory markers and specific *** current pharmacological treatment approaches available focus on reducing symptom severity while often limiting quality of life because of significant side *** has led to an effectiveness gap for IBS patients that seek further relief to increase their quality of *** and alternative medicines(CAM)have been associated with a higher degree of symptom management and quality of life in IBS *** the past decade,a number of important clinical trials have shown that specific herbal therapies(peppermint oil and Iberogast?),hypnotherapy,cognitive behavior therapy,acupuncture,and yoga present with improved treatment outcomes in IBS *** propose an integrative approach to treating the diverse symptoms of IBS by combining the benefits of and need for pharmacotherapy with known CAM therapies to provide IBS patients with the best treatment outcome *** steps in this direction are already being considered with an increasing number of practitioners recommending CAM therapies to their patients if pharmacotherapy alone does not alleviate symptoms sufficiently.

关键词： Irritable bowel syndrome Complementary and alternative medicine Hypnotherapy Cognitive behavioral therapy Herbal therapy Peppermint

Influence of high- and low-volume liver surgery in gallbladder carcinoma

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World Journal of Gastroenterology 2014年第48期20卷 18445-18451页

作者： Thorsten oliver Goetze Vittorio Paolucci Department of Surgery Ketteler-Krankenhaus 63071 Offenbach Germany

AIM: To clarify whether the performance of liver resections (LR) for incidental gallbladder carcinoma (IGBC)’s depends more on the experience of the hospitals in liver surgery than on complying with the guidelines in... 详细信息

关键词： Gallbladder carcinoma Radical cholecystectomy High-volume center German-registry Volume cut-off Hepatobiliary surgery

SCHAUSPIELER,JAGER UND GLADIATOREN:BEMERKUNGEN ZUR"TRUPPENBETREUUNG"IN DER KAISERZEITLICHEN ARMEE ROMS

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Journal of Ancient Civilizations 2022年第1期37卷 97-141,144,145页

作者： oliver Stoll Universitat Passau

*** und Kultur-getrennte Welten?Quellenzeugnisse wie das Grabepigramm des,Bauern und Soldaten'Priscus aus Kaisareia/Hadrianopolis’versetzen so manchen in Staunen:Denn dieser Mann kehrte nach dem ehrenvollen Dienst.

关键词： get Ein des

Confucianism in the Perspective of Global Science-A Review of Reconceptualizing Confucian Philosophy in the 21st Century

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Frontiers of Philosophy in China 2018年第1期13卷 150-163页

作者： oliver Davies School of Philosophy Renmin University of China Beijing 100872 China

Today, Confucianism appears as a pre-eminently philosophical approach to the human, which, though deeply rooted in an ancient history in Chinese-speaking lands, now also has the potential to become a global philosophy. In its prescription of a distinctively disciplined way of life, it parallels world religions. However, Confucianism makes no claim to revelation, and so potentially offers a universalist understanding of what it is to be a human being. The fact that the nature or meaning of embodied Confucian life also points to specific social and political structures--even though these may be subject to variation--further suggests that such a universalist anthropology could be one which potentially, though still anchored in philosophy, has concrete content. There are two main challenges to be faced, however. First, there is the need for a reconceptualization of Confucianism in order for it to function as a truly contemporary thought-form. Second, there is the need to discover ways in which the themes and concepts of Confucianism can meaningfully inform our contemporary social and political realities beyond the scope of Chinese language and history. However, these challenges have, in many ways, become less daunting in recent years. Today, there is a new openness for a transcultural, globally-oriented ethical thinking and presence which can foster stability in times of rapid and unpredictable change. And there is a new acceptance that such a practical philosophy, or philosophy of human practice, as a properly global phenomenon could have its origins in China.

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