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Agent-based modeling of COvID-19 outbreaks for New York state and UK:Parameter identification algorithm

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Infectious Disease Modelling 2022年第1期7卷 30-44页

作者： olga Krivorotko Mariia Sosnovskaia Ivan vashchenko Cliff Kerr Daniel Lesnic Institute of Computational Mathematics and Mathematical Geophysics Siberian Branch of the Russian Academy of Sciences 6 Prospect Akademika Lavrentieva StreetNovosibirsk630090Russia Novosibirsk State University 2 Pirogova StreetNovosibirsk630090Russia Institute for Disease Modeling Bill&Melinda Gates FoundationSeattleUSA University of Leeds LS29JTUK

This paper uses Covasim,an agent-based model(ABM)of COvID-19,to evaluate and scenarios of epidemic spread in New York State(USA)and the *** parameters such as contagiousness(virus transmission rate),initial number of infected people,and probability of being tested depend on the region's demographic and geographical features,the containment measures introduced;they are calibrated to data about COvID-19 spread in the region of *** the first stage of our study,epidemiological data(numbers of people tested,diagnoses,critical cases,hospitalizations,and deaths)for each of the mentioned regions were *** data were characterized in terms of seasonality,stationarity,and dependency spaces,and were extrapolated using machine learning techniques to specify unknown epidemiological parameters of the *** the second stage,the Optuna optimizer based on the tree Parzen estimation method for objective function minimization was applied to determine the model's unknown *** model was validated with the historical data of *** modeled results of COvID-19 spread in New York State and the UK have demonstrated that if the level of testing and containment measures is preserved,the number of positive cases in New York State remain the same during March of 2021,while in the UK it will reduce.

关键词： Epidemiology Agent-based modeling COvID-19 Interventions analysis Coronavirus data analysis Forecasting scenarios Reproduction number Optimization Parameter identification

INITIAL vALUE TECHNIQUES FOR THE HELMHOLTZ AND MAXWELL EQUATIONS

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Journal of Computational Mathematics 2007年第3期25卷 368-373页

作者： Frank Natterer olga Klyubina Department of Mathematics University of MünsterGermany

We study the initial value problem of the Helmholtz equation with spatially variable wave number. We show that it can be stabilized by suppressing the evanescent waves. The stabilized Helmholtz equation can be solved numerically by a marching scheme combined with FFT. The resulting algorithm has complexity n^2 log n on a n x n grid. We demonstrate the efficacy of the method by numerical examples with caustics. For the Maxwell equation the same treatment is possible after reducing it to a second order system. We show how the method can be used for inverse problems arising in acoustic tomography and microwave imaging.

关键词： Stability of elliptic initial value problems Parabolic wave equation Inverseproblems in acoustics and electromagnetics.

Biotechnical system based on fuzzy logic prediction for surgical risk classification using analysis of current-voltage characteristics of acupuncture points

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Journal of Integrative Medicine 2022年第3期20卷 252-264页

作者： Sergey Filist Riad Taha Al-Kasasbeh olga Shatalova Nikolay Korenevskiy Ashraf Shaqadan Zeinab Protasova Maksim Ilyash Mikhail Lukashov Department of Biomedical Engineering Southwest State UniversityKursk 305040Russian Federation Electrical Energy Department Balqa Applied UniversityAmman 11937Jordan Civil Engineering Department Zarqa UniversityZarqa Governorate 13222Jordan Saint-Petersburg National Research University of Information Technologies Mechanics and OpticsSaint-Petersburg 197101Russian Federation Pediatric Faculty Kursk State Medical UniversityKursk 305041Russian Federation

Objective:This study aimed to develop expert fuzzy logic model to assist physicians in the prediction of postoperative complications of prostatic hyperplasia before ***:A method for classification of surgical risks was *** effect of rotation of the current–voltage characteristics at biologically active points(acupuncture points)was used for the formation of classifier *** effect determined reversible and non-reversible changes in electrical resistance at acupuncture points with periodic exposure to a sawtooth probe ***,the developed method was tested on the prediction of the success of surgical treatment of benign prostatic ***:Input descriptors were obtained from collected data including current-voltage characteristics of 5 acupuncture points and composed of 27 arrays feeding in the *** maximum diagnostic sensitivity of the classifier for the success of a surgical operation in the control sample was 88%and for testing data set prediction accuracy was 97%.Conclusion:The use of tuples of current-voltage characteristic descriptors of acupuncture points in the classifiers could be used to predict the success of surgical treatment with satisfactory *** model can be a valuable tool to support physicians’diagnosis.

关键词： Biologically active point Acupuncture Current-voltage characteristic Descriptor Neural network

Perioperative coagulation activation after permanent pacemaker placement

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World Journal of Cardiology 2023年第4期15卷 174-183页

作者： Roman Kalinin Igor Suchkov vladislav Povarov Nina Mzhavanadze olga Zhurina Department of Cardiovascular Endovascular Surgery and Diagnostic RadiologyRyazan State Medical UniversityRyazan 390026Russia Department of Surgical Treatment of Cardiac Arrhythmias and Cardiac Pacing Ryazan State"Regional Clinical Cardiology Dispensary"Ryazan 390026Russia Scientific and Clinical Center for Hematology Oncology and ImmunologyRyazan State Medical UniversityRyazan 390026Russia

BACKGROUND Bradyarrhythmias are typically treated with permanent pacemakers(PM). The elimination of bradyarrhythmia by PM implantation improves the patient’s quality of life and prognosis, but it can also result in a number of sequalae. It is still unclear how PM implantation affects the hemostasis system’s parameters and how such parameters relate to different consequences after PM *** To assess the blood coagulation factor activity in PM patients throughout the perioperative *** Patients treated in the Department of Surgical Therapy of Cardiac Arrhythmias and Pacing at the Ryazan State "Regional Clinical Cardiology Dispensary" from April 2020 to December 2021 were included in the study. Before surgery, 7 and 30 d after PM placement, peripheral venous blood samples were withdrawn to measure the level of blood coagulation factor Ⅰ(FⅠ) and the activity of blood coagulation factors Ⅱ(FⅡ), Ⅴ(FⅤ), Ⅶ(FⅦ), Ⅷ(FⅧ), ⅸ(Fⅸ), ⅹ(Fⅹ), Ⅺ(FⅪ), Ⅻ(FⅫ). We used an automatic coagulometer Sysmex CA 660(Sysmex Europe, Germany) and reagents from Siemens(Siemens Healthcare Diagnostics Products GmbH, Germany).RESULTS The study included 146 patients. The activity of factors FⅤ [147.7(102.1-247.55)% vs 103.85(60-161.6)% vs 81.8(67.15-130.65)%, P = 0.002], FⅧ [80.4(60.15-106.25)% vs 70.3(48.5-89.1)% vs 63.7(41.6-88.25)%, P = 0.039], Fⅸ [86.2(70.75-102.95)% vs 75.4(59.2-88.3)% vs 73.9(56.45-93.05)%, P = 0.014], Fⅹ [188.9(99.3-308.18)% vs 158.9(83.3-230)% vs 127.2(95.25-209.35)%, P = 0.022], FⅪ [82.6(63.9-103.6)% vs 69.75(53.8-97.6)% vs 67.3(54.25-98.05)%, P = 0.002], FⅫ [87.6(67.15-102.3)% vs 78.9(63.4-97.05)% vs 81.2(62.15-97.4)%, P vity [157.9(109.7-245.25)% vs 130(86.8-192.5)% vs 144.8(103.31-185.6)%, P = 0.021] decreased at 7 d and increased at 30 d postoperatively. There were no statistically significant changes in the FvII activity within 30 d after PM placement [182.2(85.1-344.8)% vs 157.2(99.1-259)% vs 108.9(74.9

关键词： Hemostasis Blood coagulation Cardiac pacemaker Anticoagulants Postoperative complications

Influence of free fatty acid content and degree of fat saturation on production performance,nutrient digestibility,and intestinal morphology of laying hens

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Animal Nutrition 2023年第2期13卷 313-323页

作者： María Palomar Carlos Garces-Narro olga Piquer Roser Sala Alba Tres Jose AGarcía-Bautista María D.Soler AviFeed Science Department of Animal Production and HealthFacultad de VeterinariaUniversidad CEU Cardenal Herrera e CEU UniversitiesE-46115Alfara de PatriarcaValenciaSpain Animal Nutrition and Welfare Service Department of Animal and Food ScienceFacultat de VeterinariaUniversitat Autonoma de BarcelonaE-08193BellaterraBarcelonaSpain Departament de Nutrici Ciencies de l’Alimentaci i GastronomiaFacultat de Farmacia i Ciencies de l’AlimentaciUniversitat de BarcelonaE-08921Santa Coloma de GramenetBarcelonaSpain

This study was conducted to evaluate the effects of dietary free fatty acid(FFA)content and degree of fat saturation on production performance,lipid and calcium digestibility,and intestinal function of laying *** a 15-week period,a total of 144 laying hens(19 weeks old)were randomly assigned to 8 dietary treatments,which were obtained by gradually replacing crude soybean oil with soybean acid oil(AO),or crude palm oil with palm fatty acid distillate(FAD).Thus,there were 4 soybean and 4 palm diets with 6%added fat varying in their FFA percentage(10%,20%,30%,and 45%),following a 2×4 factorial *** treatment included 6 replicates with 3 birds per *** daily feed intake and final body weight were significantly higher in palm diets(Pversion *** levels of FFA in soybean diets resulted in lower egg production and higher egg weight(linear,Pvely affected the digestibility of EE and calcium(Pving little effect on FA *** was a significant interaction in the AME;lower values were reported in soybean diets as the dietary FFA percentage increased(linear,Pvillus height and higher villus height-to-crypt depth ratio than palm diets(Pvillus height-to-crypt depth ratio(linear,Pvarying dietary FFA content did not affect fat utilization as much as the degree of saturation did,supporting the use of AO and FAD as alternative fat ingredients.

关键词： Acid oil Fat by-product Fatty acid distillate Lipid Calcium

Processing Methods of Alkaline Hydrolysate from Rice Husk

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Rice science 2017年第4期24卷 235-240页

作者： olga D.AREFIEvA Liudmila A.ZEMNUKHOvA Anastasia A.KOvSHUN Anna v.KOvEKHOvA Far Eastern Federal University Vladivostok 690950Russian Federation Institute of Chemistry Far-Eastern BranchRussian Academy of SciencesVladivostok 690022Russian Federation

This paper devoted to finding processing methods of alkaline hydrolysate produced from rice husk pre-extraction, and discusses alkaline hydrolysate processing schemed and disengagement of some products： amorphous silica of various quality, alkaline lignin, and water and alkaline extraction polysaccharides. Silica samples were characterized： crude （air-dried）, burnt （no preliminary water treatment）, washed in distilled water, and washed in distilled water and burnt. Waste water parameters upon the extraction of solids from alkaline hydrolysate dropped a few dozens or thousand times depending on the applied processing method. Color decreased a few thousand times, turbidity was virtually eliminated, chemical oxygen demanded about 20–136 times; polyphenols content might decrease 50% or be virtually eliminated. The most prospective scheme obtained the two following solid products from rice husk alkaline hydrolysate： amorphous silica and alkaline extraction polysaccharide. Chemical oxygen demand of the remaining waste water decreased about 140 times compared to the silica-free solution.

关键词： rice husk alkaline hydrolysate silica lignin polysaccharide

3D model of Svecofennian Accretionary Orogen and Karelia Craton based on geology,reflection seismics,magnetotellurics and density modelling:Geodynamic speculations

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Geoscience Frontiers 2020年第3期11卷 999-1023页

作者： Michael v.Mints victor N.Glaznev olga M.Muravina Elena Yu Sokolova Geological Institute RASMoscowRussia voronezh State University VoronezhRussia Schmidt Institute of Physics of the Earth RASMoscowRussia All-Russian Research Geological Oil Institute MoscowRussia

A 3D model of deep crustal structure of the Archaean Karelia Craton and late Palaeoproterozoic Svecofennian Accretionary Orogen including the boundary zone is *** model is based on the combination of data from geological mapping and reflection seismic studies,along profiles 1-EU,4 B,FIRE-1-2 a-2 and FIRE-3-3 a,and uses results of magnetotelluric soundings in southern Finland and northern Karelia.A seismogeological model of the crust and crust-mantle boundary is compared with a model of subhorizontal velocity-density layering of the *** TTG-type crust of the Palaeoarchaean and Mesoarchaean microcontinents within the Karelia Craton and the Belomorian Province are separated by gently dipping greenstone belts,at least some of which are *** structure of the crust was determined mainly by Palaeoproterozoic tectonism in the intracontinental settings modified by a strong collisional compression at the end of the *** insights into structure,origin and evolution of the Svecofennian Orogen are *** accretionary complex is characterized by inclined tectonic layering:the tectonic sheets,~15 km thick,are composed of volcanic-sedimentary rocks,including electro-conductive graphite-bearing sedimentary rocks,and electro-resistive granitoids,which plunge monotonously and consecutively *** reaching the level of the lower crust,the tectonic sheets of the accretionary complex lose their distinct *** the seismic reflection pattern they are replaced by a uniform acoustically translucent medium,where separate sheets can only be traced *** crust-mantle boundary bears a diffuse character:the transition from crust to mantle is recorded by the disappearance of the vaguely drawn boundaries of the tectonic sheets and in the gradual transition of acoustically homogeneous and translucent lower crust into transparent *** the effect of endogenic heat flow,the accretionary complex underwent high-temperatu

关键词： Reflection seismics Magnetotellurics Svecofennian accretionary Orogen Svecofennian Ocean 3D crustal model velocity-density layering

Convective Instability and Appearance of Structured Flows for Diffusion in Multicomponent Gas Mixtures

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Transactions of Nanjing University of Aeronautics and Astronautics 2014年第2期31卷 142-146页

作者： vladimir N. Kossov~ olga v. Fedorenko Yelena A. Dyachenko Kazakh National Pedagogical University Almaty 050100 Republic of Kazakhstan Institute of Experimental and Theoretical Physics al-Farabi Kazakh National University Almaty 050038 Republic of Kazakhstan Kazakh Academy of Transport and Communications Names after M. Tynyshpayev Almaty 050012 Republic of Kazakhstan

The main objective of this article is to investigate the behavior of gaseous systems with two and more independent gradients or thermodynamic forces exhibiting complicated behavior,when the convective flows *** existence of structural formations in these systems is shown by the schlieren method and the fast-response *** linear analysis of stability can explain reasons of the appearance of convective instability in multicomponent gas mixtures.

关键词： diffusion instability of mechanical equilibrium theory of stability partial Rayleigh numbers

The role of NLRP3 inflammasome for microglial response to peripheral inflammation

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Neural Regeneration Research 2021年第2期16卷 294-295页

作者： olga Garaschuk Institute of Physiology Department of NeurophysiologyEberhard Karls University of TübingenTübingenGermany

Systemic inflammation is often accompanied by adaptive responses mediated by the central nervous system, such as lack of motivation andattention, fatigue, malaise, irritation oreven depression. This symptoms aresummar... 详细信息

关键词： motivation such NLRP3