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Photodynamic Therapy for Gynecological Diseases and Breast Cancer

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Clinical oncology and cancer researeh 2012年第1期9卷 9-17页

作者： Natashis Shishkova olga Kuznetsova Temirbolat Berezov Department of Biochemistry School of MedicinePeople's Friendship University of Russia

Photodynamic therapy （PDT） is a minimally invasive and promising new method in cancer treatment. Cytotoxic reactive oxygen species （ROS） are generated by the tissueqocalized non-toxic sensitizer upon illumination and in the presence of oxygen. Thus, selective destruction of a targeted tumor may be achieved. Compared with traditional cancer treatment, PDI has advantages including higher selectivity and lower rate of toxicity. The high degree of selectivity of the proposed method was applied to cancer diagnosis using fluorescence. This article reviews previous studies done on PDT treatment and photodetection of cervical intraepithelial neoplasia, vulvar intraepithelial neoplasia, ovarian and breast cancer, and PDT application in treating non-cancer lesions. The article also highlights the clinical responses to PDT, and discusses the possibility of enhancing treatment efficacy by combination with immunotherapy and targeted therapy.

关键词： photodynamic therapy photosensitizers cervical/vulvar intraepithelial neoplasia ovarian neoplasms breast neoplasms

Comparative Analyses of Russia,China,and the USA Initiatives in Central Asia

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Comparative Analyses of Russia,China,and the USA Initiatives...

作者： Popova olga 华东师范大学

学位级别：硕士

伴随着全球化及全球主义的进程,国际关系中的区域体系受到了越来越多的关注,区域性国际政治的重要性在持续上升。过去的十年中,中美俄根据各自在区域利益的变化,相应做出了调整其区域政策的行为。其中,三国在中亚的利益博弈被描述为“... 详细信息

伴随着全球化及全球主义的进程,国际关系中的区域体系受到了越来越多的关注,区域性国际政治的重要性在持续上升。过去的十年中,中美俄根据各自在区域利益的变化,相应做出了调整其区域政策的行为。其中,三国在中亚的利益博弈被描述为“新大博弈。本文对比分析了“欧亚经济联盟”、“一带一路”与“新丝绸之路”,重点关注了中美俄三国的倡议是如何被制定以及三国的精英又是如何理解其区域国际政治的。文章认为,中美俄在中亚的区域的倡议体现了大国对于中亚区域主义的不同理解。与俄罗斯和美国从领土角度来定义区域主义不同,中国强调区域主义的功能性,通过区域主义增加其与外部国家的联系。俄罗斯从领土性来看待区域主义,将区域主义看作是后苏联空间一体化创造有利条件的一种方式。美国的“新丝绸之路”倡议也具有地缘色彩,试图在“大中亚主义”的框架下整合中亚秩序,改变中亚地区格局。对区域秩序安排的不同视角带来了不同倡议之间互补的可能性。“一带一路”为“欧亚经济联盟”提供了新机遇。同时,中国通过“欧亚经济联盟”也为中国投资者获得了一个好的合作平台。中美两国有众多共同利益,可以在电力、海关管理和交通运输领域进行合作。通过对中美俄三国倡议在哈萨克斯坦的实施效果进行评估可以看到,“一带一路”提升了哈萨克斯坦与其它“一带一路”沿线国家的经济联系;“欧亚经济联盟”增加了联盟和哈萨克斯坦的经济实力;美国“新丝绸之路”为中亚国家建立了更强大的连通。本文尝试能通过梳理中美俄在中亚地区提倡的不同区域主义,评估这些倡议之间可能存在的挑战与合作,有助于推动倡议的落实以及维护中亚地区的和平与稳定。

关键词：中亚欧亚经济联盟新丝绸之路丝绸之路经济带外交政策

Growth of the tufted-tailed rat

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Integrative Zoology 2007年第4期2卷 205-211页

作者： Vololomboahangy R.RANDRIANJAFY olga RAMILIJAONA Daniel RAKOTONDRAVONY Department of Animal Biology and Ecology University of MahajangaMahajangaMadagascar Department of Animal Biology University of AntananarivoAntananarivoMadagascar

Eliurus myoxinus (Rodentia: Nesomyidae, Nesomyinae) is one of the four species of endemic Malagasy rodentsknown to exist in the Ankarafantsika National Park, northwestern Madagascar. In order to study growth parametersand to determine at which age E. myoxinus commences breeding, we used two different techniques: captivebreeding and a capture-mark-release field program in the species’ natural habitat. The data collected on thebreeding of E. myoxinus in captivity demonstrated that females can give birth to a litter of up to four pups, with upto four litters per calendar year. Reproduction of E. myoxinus was more likely to be continuous in captivity thanunder natural habitat conditions. If parturition failed, then post-partum mating occurred. Pups had a rapid lineargrowth phase from birth until 1 month of age. Between 1.5 and 2 months of age, the growth rate continued toincrease, but then decreased at around the time of weaning, which occurred by 3.5 months of age. The successivemaximum method of age determination showed that individuals at the “young” stage had an average body length of90 mm and a weight of 30 g and were between 1.5 and 2 months old. The greatest variation in measurements ofjuveniles occurred at the age of 3.5 months. At this stage, sub-adults resembled adults but their external genitaliawere not well developed. Individuals were classified as adults if they had reached a body length of 110 mm and abody weight of 40 g. This occurred at more than 4.5 months of age when the animals were generally reproductivelyactive. The Von Bertalanffy method indicated that individuals reach the adult stage by 6 to 7 months. Males grewmore rapidly than females, reaching adulthood by 5.5 months of age, whereas females only reached adulthoodseveral weeks later. This species is polygamous. The sex ratio of pups at birth favored females by approximately3:1. The higher proportion of female pups at birth may represent a survival strategy of this species, possiblyassociated w

关键词： captive breeding Eliurus myoxinus growth growth rate life cycle.

Composition and Physico-Chemical Properties of Meat from Capons Fed Cereals

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Journal of Integrative Agriculture 2013年第11期12卷 1953-1960页

作者： olga Díaz Luisana Rodríguez Alexandr Torres ngel Cobos Food Technology Division Department of Analytical ChemistryNutrition and Food ScienceFaculty of SciencesUniversity of Santiago de Compostela

Chemical composition, physico-chemical properties and fatty acid composition of breast and drumstick meat from capons （castrated male cockerels） fed cereals were studied. Three groups of capons were reared. One group was fed ad libitum the same commercial diet until the 4th mon of life. The last month of its life, the capons of this group were fed corn. The second and third group of capons were fed the same diet from caponization. The second group was fed mixture of corn （50%） and wheat （50%）. The third group of capons was fed 2/3 corn and 1/3 mixture of corn （50%） and barley （50%）. Capons were reared under free-range conditions and slaughtered at 150 d of age. Caponization was performed at 48 d. No signiifcant effects of feeding in chemical composition, pH, water holding capacity, drip and cooking losses and texture of the meat were observed. The meat of the third group （capons fed 83%corn） was more yellow and showed higher content of C18：2 than that of the other capons.

关键词： castrated male cockerel feeding meat quality fatty acids

A New Three-Dimensional(3D)Printing Prepress Algorithm for Simulation of Planned Surgery for Congenital Heart Disease

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Congenital Heart Disease 2023年第5期18卷 491-505页

作者： Vitaliy Suvorov olga Loboda Maria Balakina Igor Kulczycki Department of Surgical Diseases of Children Saint Petersburg State Pediatric Medical UniversitySaint PetersburgRussia Higher School of Theoretical Mechanics Peter the Great Saint Petersburg Polytechnic UniversitySaint PetersburgRussia

Background:Three-dimensional printing technology may become a key factor in transforming clinical practice and in significant improvement of treatment *** introduction of this technique into pediatric cardiac surgery will allow us to study features of the anatomy and spatial relations of a defect and to simulate the optimal surgical repair on a printed model in every individual ***:We performed the prospective cohort study which included 29 children with congenital heart *** hearts and the great vessels were modeled and printed *** of the same cardiac areas were taken in the same planes and points at multislice computed tomography images(group 1)and on printed 3D models of the hearts(group 2).Pre-printing treatment of the multislice computed tomography data and 3D model preparation were performed according to a newly developed ***:The measurements taken on the 3D-printed cardiac models and the tomographic images did not differ significantly,which allowed us to conclude that the models were highly accurate and *** new algorithm greatly simplifies and speeds up the preparation of a 3D model for printing,while maintaining high accuracy and level of ***:The 3D-printed models provide an accurate preoperative assessment of the anatomy of a defect in each *** new algorithm has several important advantages over other available *** enable the development of customized preliminary plans for surgical repair of each specific complex congenital heart disease,predict possible issues,determine the optimal surgical tactics,and significantly improve surgical outcomes.

关键词： 3D printing imaging in cardiac surgery congenital heart disease modelling in cardiac surgery pediatric cardiology algorithmic modelling of the heart medical imaging 3D modelling

LOS and NLOS identification in real indoor environment using deep learning approach

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Digital Communications and Networks 2024年第5期10卷 1305-1312页

作者： Alicja Olejniczak olga Blaszkiewicz Krzysztof K.Cwalina Piotr Rajchowski Jaroslaw Sadowski Faculty of Electronics Telecommunications and InformaticsGdansk University of Technology

Visibility conditions between antennas,***-of-Sight(LOS) and Non-Line-of-Sight(NLOS) can be crucial in the context of indoor localization,for which detecting the NLOS condition and further correcting constant position estimation errors or allocating resources can reduce the negative influence of multipath propagation on wireless communication and *** this paper a Deep Learning(DL) model to classify LOS/NLOS condition while analyzing two Channel Impulse Response(CIR) parameters:Total Power(TP) [dBm] and First Path Power(FP) [dBm] is *** experiments were conducted using DWM1000 DecaWave radio module based on measurements collected in a real indoor environment and the proposed architecture provides LOS/NLOS identification with an accuracy of more than 100% and 95% in static and dynamic senarios,*** proposed model improves the classification rate by 2-5% compared to other Machine Learning(ML) methods proposed in the literature.

关键词： Deep learning Machine learning LOS NLOS UWB

Review of state-of-the-art decision support systems (DSSs) for prevention and suppression of forest fires

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Journal of Forestry Research 2017年第6期28卷 1107-1117页

作者： Stavros Sakellariou Stergios Tampekis Fani Samara Athanassios Sfougaris olga Christopoulou Department of Planning and Regional Development University of Thessaly 38334 Volos Greece Department of Agriculture Crop Production and Rural Environment University of Thessaly 38446 Volos Greece

Forest ecosystems are our priceless natural resource and are a key component of the global carbon budget. Forest fires can be a hazard to the viability and sustainable management of forests with consequences for natural and cultural environments, economies, and the life quality of local and regional populations. Thus, the selection of strategies to manage forest fires, while considering both functional and economic efficiency, is of primary importance. The use of decision support systems(DSSs) by managers of forest fires has rapidly increased. This has strengthened capacity to prevent and suppress forest fires while protecting human lives and property. DSSs are a tool that can benefit incident management and decision making and policy, especially for emergencies such as natural disasters. In this study we reviewed state-of-the-art DSSs that use: database management systems and mathematical/economic algorithms for spatial optimization of firefighting forces; forest fire simulators and satellite technology for immediate detection and prediction of evolution of forest fires; GIS platforms that incorporate several tools to manipulate, process and analyze geographic data and develop strategic and operational plans.

关键词： Decision support systems Fire behavior simulation Forest fires Geographic information system Mathematical algorithms Risk management

Risk Management of the Oil and Gas Project in PJSC LUKOIL

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Risk Management of the Oil and Gas Project in PJSC LUKOIL

作者： olga Kozakevich 山东大学

学位级别：硕士

本文以俄罗斯石油和天然气PJSC(公共股份公司)LUKOIL为研究对象,目的是对公司油气项目面临的风险及如何应对进行研究。本文在风险类型系统化的基础上,识别了油气项目中的主要风险。在外部风险中,本文确定了政治,宏观经济风险,金融风险,... 详细信息

本文以俄罗斯石油和天然气PJSC(公共股份公司)LUKOIL为研究对象,目的是对公司油气项目面临的风险及如何应对进行研究。本文在风险类型系统化的基础上,识别了油气项目中的主要风险。在外部风险中,本文确定了政治,宏观经济风险,金融风险,法律风险,建筑风险和地质风险的类别。本文建议对以下类别的内部风险进行分析:生产活动的风险,支持活动的风险,流通领域的风险以及管理领域的风险。本文介绍了有关石油和天然气公司的石油开采和提炼部门对这些风险的专家评估结果,并提出了有关企业风险管理的建议。论文研究的基础数据来自媒体出版物,互联网信息材料,当前国家档案馆的材料,双边协议和条约。该研究的方法论基础有可持续发展的概念,生产数字化的概念,生产生命周期的理论,组织风险管理流程。论文实际数据使用来自俄罗斯卢克石油公司的实际石油和天然气项目。根据本文研究工作的需要,部分研究数据来自于二手数据。本文的结论和建议对改善石化企业的项目管理具有参考作用。

关键词：风险管理项目石油和天然气

New Design of Textile Vascular Prostheses for the Reconstruction of Small Diameter Vascular Blood Vessels

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Journal of Donghua University(English Edition) 2013年第5期30卷 401-405页

作者： CHRZANOWSKA olga STRUSZCZYK Marcin Henryk KRUCINSKA Izabella Department of Material and Commodity Sciences and Textile Metrology Center of Advanced Technologies of Human Friendly Textiles PRO HUMANO TEXFaculty of Material Technologies and Textile DesignUniversity of Technology

The general object of research is to design new idea of the semi-biodegradable,multilayered vascular prosthesis used for the reconstruction of significantly small diameter vascular vessels( microreconstruction). The paper studies the selection of appropriate sterilization technique for resorbable tubular structures made of poly( L-lactide-co-glicolide)( PLAGA) and nonbiodegradable tubular structures made of polypropylene( PP). The designed grafts are characterized by the physical properties as well as mechanical properties according to ISO 7198 ∶ 1998 ***,the process of the grafts fabrication will be explained considering the stages affected the critical properties of the elaborated textile implants. The increase of PLAGA melt-electrospun tubular structures mechanical properties was observed due to the thermal stabilization use. The ethylene oxide( EO) and steam sterilization had a destructive effect on the designed PLAGA meltelectrospun tubular, fibrous structures, whereas the irradiation yielded in the changes in mechanical and physical properties on the acceptable level,taking into account the future clinical applications.

关键词： vascular prostheses melt-electrospinning melt-blown sterilization