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作者： Olumuyiwa L.Ogegbo Wimal Dissanyake John Crowder olayinka Asekun Oluwole Familoni Christopher J.Branford-White S.W. AnnieBligh 张华琦尼日利亚拉各斯大学科学学院化学系

当今,代谢组学研究已广泛应用于解析领域,例如药物的发现和毒理学研究、疾病的诊断以及营养基因组学。由于代谢组学研究自身的优势,它被认为比其他传统的体外研究具备更为广泛的应用前景,目前将代谢组学应用于探索膳食中主要生物活性成...

当今,代谢组学研究已广泛应用于解析领域,例如药物的发现和毒理学研究、疾病的诊断以及营养基因组学。由于代谢组学研究自身的优势,它被认为比其他传统的体外研究具备更为广泛的应用前景,目前将代谢组学应用于探索膳食中主要生物活性成分的生化作用已成为研究热点。豆浆是由富含植物雌激素(异黄酮类)的大豆制成。所谓的植物雌激素包括大豆黄酮、三羟异黄酮、大豆黄素、异黄酮苷、染料木苷和黄豆黄苷。与人体中的雌激素相比,这

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Innovations in the Implementation of Polio Surveillance Enhancement Plan in Oyo State, Nigeria: Key Benefits, Lessons Learned, Challenges and Opportunities

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Health 2022年第4期14卷 442-455页

作者： Enya Bassey Bassey Walter Kazadi Mulomb Ahmed Mohamed Ahmed Khedr Rosemary Ifeoma Onyibe Olufunmilola Olawumi Kolude Oluwadare Marcus Oluwabukola Alawale Oluwatobi Adeoluwa Iyanda Omotunde Ogunlaja Taiwo Olabode Ladipo Maxwell Obeka Adeniyi Ayobami Adeniran Oluyinka Motunrayo Dania Olabumuyi Olubumi Olayide Oluwaseun Opeyemi Oni Moshood Babatunde Busari Faith Ehiaghe Ugba Ayobami Desmond Olatimehin Gbenga Stanley olayinka Abayomi Oluwasegun Ayinde Chinwe Grace Azuka Olufemi Toheeb Okuneye Ahmed Bello World Health Organization (WHO) Nigeria Country Office Abuja Nigeria Oyo State Emergency Operation Center Ministry of Health Ibadan Nigeria

Background: Nigeria attained the milestone of being certified wild poliovirus free in the year 2020. However, a drop in the key performance indicators of polio surveillance system was across various Local Government Areas (LGAs) in Oyo State. This drop highlighted the need for an innovative way of enhancing polio surveillance in Oyo State. Methods: This study was conducted in four phases and each phase utilized a cross-sectional study design and purposive sampling technique to select eligible LGAs and participants. LGAs that met at least two of the set-out criteria (had not reported at least a case of Acute Flaccid Paralysis (AFP) 12 months preceding the survey, with decline in AFP case detection rate, had not met AFP key indicators, are densely populated, and has an international border) were selected. A concurrent mixed method of data collection was utilized, and quantitative data were collected with a semi-structured questionnaire administered using Computer Assisted Personal Interviews (CAPI) during community active case search, health facility retroactive case search (HFRACS). Qualitative data collection was done through Focus Group Discussion (FGD). Surveillance intensification activities were conducted over eight weeks period. Data were analyzed using Microsoft Excel Software;summarization was done using frequencies and percentages while presentation was done using charts and spot maps. Results: A total of 1277, 49, 259 and 632 settlements, households and health facilities respectively were visited across 24 (73%) LGAs in Oyo State. Of the 150 suspected AFP cases identified, 45 (30%) were rejected cases, 33 (22%) were missed cases and 72 (48%) were true AFP cases. Non-Polio AFP Rate (NP-AFP rate) increased from 2.7 to 6.9 (P Conclusions: Innovative strategies implemented in AFP surveillance across Oyo State have resulted in improvement in AFP surveillance performance indicators in the State. There is therefore the need for dynamic and innovative ways of condu

关键词： Polio-Surveillance-Indicators Enhancement-Plan Innovations AFP-Case-Search

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