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Clinically Diagnosed Guillain-Barre Syndrome in Pregnancy: Case Report and Review of Literature

Case Reports in Clinical Medicine 2014年第8期3卷 487-490页

作者： Afolabi Korede Koledade Adekunle O. Oguntayo Sani A. Abubakar Godfrey K. Katung Sunday oladapo shittu Neurology Unit Internal Medicine Department Ahmadu Bello University Teaching Hospital Zaria Nigeria Obstetrics and Gynaecology Department Ahmadu Bello University Teaching Hospital Zaria Nigeria

Background: Guillain-Barre syndrome (GBS) is an autoimmune disorder characterized by a heterogeneous group of pathological and clinical entities. It is associated with ascending areflexic paralysis, some autonomic dysfunction and respiratory failure in severe cases and ultimately death if not promptly diagnosed and treated. It may be preceded by an antecedent event in about two-third of cases. This could be an upper respiratory tract infection, viral illness, recent history of vaccination, pregnancy, cancer or even trauma. The condition is exceedingly rare in pregnancy and only few cases have been reported in literature. Case Report: This is a case of a 28-year-old Gravida 3, Para 1+1 and Estimated Gestational Age of 30 weeks and 4 days. There was a history of upper respiratory tract infection eight weeks prior to presentation which spontaneously resolved. On examination, she was a young woman, anxious, weak, afebrile, not pale, the neck could not hold the head upright and there was bilateral non tender pitting pedal oedema extending to her mid-shin. There were no cranial nerve deficits and no sign of meningeal irritation. There were normal muscle bulk with global hypotonia and flaccid quadriparesis, Power was 3/5. The proximal groups of muscles were more affected than the distal parts. Reflexes were diminished globally with plantar flexor response. She had immunoglobulin as treatment. Conclusion: In a low resource setting like ours it is important to have a high index of suspicion of GBS when an apparently healthy gravid woman presents with progressive weakness of the limbs.

关键词： Guillain-Barre Syndrome Pregnancy Immunoglobulin Plasmapheresis

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Pregnancy Specific Beta-1 Glycoprotein in Women with Eclampsia, Kaduna State, Nigeria

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Open Journal of Immunology 2015年第5期5卷 260-265页

作者： Jim M. Banda Geoffrey C. Onyemelukwe Bolanle O. P. Musa oladapo S. shittu Zulai A. Sarkin-Pawa Aliyu A. Babadoko Aisha I. Mamman Adamu G. Bakari Suraj Junaid Pathology Department Faculty of Medicine Kaduna State University Kaduna Nigeria Immunology Unit Department of Medicine Ahmadu Bello University Teaching Hospital Zaria Nigeria Department of Obstetrics and Gynaecology Ahmadu Bello University Teaching Hospital Zaria Nigeria Department of Haematology and Blood Transfusion Ahmadu Bello University Teaching Hospital Zaria Nigeria Department of Medicine Ahmadu Bello University Teaching Hospital Zaria Nigeria Federal College of Veternary and Medical Laboratory National Veterinary and Research Institute Vom Nigeria

This was a comparative cross-sectional study of eclamptic and normal healthy pregnant women conducted in kaduna State, Nigeria to determine Pregnancy Specific beta-1 Glycoprotein (PSG-1) levels in the peripheral blood of third trimester women with eclampsia (EC;n = 38), normal healthy pregnant and non pregnant women controls (PC;n = 25 and NPC;n = 25 respectively), age and parity matched, attending labour rooms/wards and Antenatal Clinics (ANC) of Ahmadu Bello University Teaching Hospital Shika, Zaria and four other Hospitals in Kaduna state, Nigeria. Participants with smear positive malaria, seropositive for human immunodeficiency virus (HIV) or any other known clinical infection were excluded from this study. Pregnancy specific beta-1 glycoprotein levels were estimated using Quantikine ELISA kits. Data obtained were analyzed using SPSS version 20.0 (Chicago, USA) and Graph pad Prism 6.0. Results were expressed as mean ± standard deviation while Kruskal Wallis test was used to determine the significant differences. A p-value of less than 0.05 was considered to be significant. The mean serum level of PSG-1 in EC was 2.53 ± 0.11 pg/ml, PC;2.56 ± 0.03 pg/ml) and NPC;0.62 ± 0.20 pg/ml. There was no significant difference between EC and PC (P > 0.05). Pregnant women (with and without EC) had significantly higher mean serum values compared to NPC p < 0.05. While pregnancy was associated with high levels of PSG-1, the study did not support the hypothesis of low PSG-1 level in EC. A longitudinal study to capture changes in PSG-I levels in the course of pregnancy as they manifest is recommended.

关键词： Eclampsia Pregnancy Specific Beta-1 Glycoprotein

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Prevalence and Predictors of High-Risk HPV in Nigeria

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Advances in Infectious Diseases 2022年第4期12卷 745-757页

作者： Aigbe Gregory Ohihoin Patrick Azuka Okwuraiwe Adesola Zaidat Musa Gbenga Olorunfemi Chika Kingsley Onwuamah Fehintola Ige Olufemi Samuel Amoo Rosemary Audu Felix Okogbo Babafemi Daniyan Terrumun Swende Geoffrey Chukwubuike Onyemelukwe Haruna Daru Hadiza Usman oladapo shittu Jonah Musa Oliver Chukwujekwu Ezechi Innocent Achanya Ujah Nigerian Institute of Medical Research (NIMR) Lagos Nigeria School of Public Health University of Witwatersrand Johannesburg South Africa College of Medicine Ambrose Alli University Edo State Nigeria National Obstetric Fistula Center Abakaliki Ebonyi State Nigeria Benue State University Benue State Nigeria Ahmadu Bello University Zaria Kaduna State Nigeria University of Jos Jos Nigeria University of Maiduguri Borno State Nigeria

Introduction: Cervical cancer remains a major cause of morbidity and mortality among the female population in sub-Saharan Africa. Vaccination against human papillomavirus (HPV), the main causative agent, has the potential to eradicate cervical cancer. In-country evidence of sub-types of HPV associated with cervical cancer is scanty, thus necessitating this study. Methods: A cross-sectional study was performed using a multistage sampling technique. A molecular technique using the Cobas 4800 machine was used for genotyping. Results: 570 participants were recruited for the study. The mean age of the participants was 32.4 ± 5.2 years. The age of sexual debut ranged from 15 - 24 years with a median of 19 years. 194 participants were positive for high-risk HPV giving a prevalence of 34%. 3% (n = 17) were positive for HPV, 16. 4% (23) had a positive result for HPV, 18. 27% (n = 154) had a positive result for other high-risk groups (OHR) other than HPV 16 or 18. Positive status for high-risk HPV is associated with the presence of genital warts (OR = 7.5), a Positive HIV status (OR = 3.48), abnormal vaginal discharge (OR = 2.20), multiple sexual partners (OR = 2.30), and obesity (OR = 2.70). The prevalence of HIV in the study population was 6.84% (n = 39). Conclusion: Another High-risk HPV other than 16 and 18 appears to be the predominant form of HPV infection in Nigerian women. The risk of being positive for high-risk HPV is associated with the presence of genital warts, abnormal vaginal discharge, a positive HIV status, multiple sexual partners and Obesity. It is therefore necessary to disaggregate and study these high-risk sub-types.

关键词： HPV Cervical Cancer Prevalence Predictors Nigeria

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Prevalence and Predictors of High-Risk HPV in Nigeria

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Advances in Infectious Diseases 2022年第4期

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Storage stability of dried tomato slice

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International Journal of Agricultural and Biological Engineering 2013年第4期6卷 104-110页

作者： shittu S K Isiaka M Department of Agricultural Engineering Bayero UniversityKanoNigeria Department of Agricultural Engineering Ahmadu Bello UniversityZariaNigeria

Unlike fresh farm produce,processed fruits and vegetables such as sun dried tomatoes can be categorized as ambient temperature shelf stable ***,large quantities of these products yet easily go bad most especially when the appropriate conditions for their storage are not *** minimize these losses,it is important to know and exploit the optimum environmental conditions and moisture content range for the storage of the *** present study through systematic theoretical assertions employed by other researchers on other crops seeks to establish the storage stability of dried tomato slice at three probable temperatures of 10,30 and 45°*** showed that in this temperature range,upper limit moisture content varied between 6%-7.5%and 6.5%-8.3%*** adsorption and desorption,*** corresponding lower limit moisture contents varied between 4.29%-5.52%and 5.15%-6.29%*** order to minimize moisture migration into or out of dried tomato slice during storage,the study revealed that the product should be stored within 29%-62%relative humidity.

关键词： dried tomato storage stability moisture content humidity temperature

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Dual solutions of MHD stagnation point flow and heat transfer over a stretching/shrinking sheet with generalized slip condition

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Journal of Central South University 2015年第6期22卷 2376-2384页

作者： ABBAS Zaheer MASOOD Tahmina OLANREWAJU Philip oladapo Department of Mathematics The Islamia University of Bahawalpur Department of Mathematical Sciences Oduduwa University

An analysis was made to study the steady momentum and heat transfer characteristics of a viscous electrically conducting fluid near a stagnation point due to a stretching/shrinking sheet in the presence of a transverse magnetic field and generalized slip condition. Two flow problems corresponding to the planar and axisymmetric stretching/shrinking sheet were considered. By means of similarity transformations, the obtained resultant nonlinear ordinary differential equations were solved numerically using a shooting method for dual solutions of velocity and temperature profiles. Some important physical features of the flow and heat transfer in terms of the fluid velocity, the temperature distribution, the skin friction coefficient and the local Nusselt number for various values of the controlling governing parameters like velocity slip parameter, critical shear rate, magnetic field, ratio of stretching/shrinking rate to external flow rate and Prandtl number were analyzed and discussed. An increase of the critical shear rate decreases the fluid velocity whereas the local Nusselt number increases. The comparison of the present numerical results with the existing literature in a limiting case is given and found to be in an excellent agreement.

关键词： dual solutions stagnation-point MHD flow slip condition heat transfer numerical solution transverse magnetic fields

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Catalysis of semihydrogenation of acetylene to ethylene: current trends, challenges, and outlook

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Frontiers of Chemical Science and Engineering 2022年第7期16卷 1031-1059页

作者： Toyin D.shittu Olumide B.Ayodele Department of Chemical and Petroleum Engineering United Arab Emirates UniversityAl-Ain 15551United Arab Emirates Department of Micro and Nanofabrication International Iberian Nanotechnology LaboratoryBraga 4715-330Portugal School of Chemical Engineering Engineering CampusUniversity of Science MalaysiaNibong Tebal 14300Malaysia

Ethylene is an important feedstock for various industrial processes, particularly in the polymer industry. Unfortunately, during naphtha cracking to produce ethylene, there are instances of acetylene presence in the product stream, which poisons the Ziegler–Natta polymerization catalysts. Thus, appropriate process modification, optimization, and in particular, catalyst design are essential to ensure the production of highly pure ethylene that is suitable as a feedstock in polymerization reactions. Accordingly, carefully selected process parameters and the application of various catalyst systems have been optimized for this purpose. This review provides a holistic view of the recent reports on the selective hydrogenation of acetylene. Previously published reviews were limited to Pd catalysts. However, effective new metal and non-metal catalysts have been explored for selective acetylene hydrogenation. Updates on this recent progress and more comprehensive computational studies that are now available for the reaction are described herein. In addition to the favored Pd catalysts, other catalyst systems including mono, bimetallic, trimetallic, and ionic catalysts are presented. The specific role(s) that each process parameter plays to achieve high acetylene conversion and ethylene selectivity is discussed. Attempts have been made to elucidate the possible catalyst deactivation mechanisms involved in the reaction. Extensive reports suggest that acetylene adsorption occurs through an active single-site mechanism rather than via dual active sites. An increase in the reaction temperature affords high acetylene conversion and ethylene selectivity to obtain reactant streams free of ethylene. Conflicting findings to this trend have reported the presence of ethylene in the feed stream. This review will serve as a useful resource of condensed information for researchers in the field of acetylene-selective hydrogenation.

关键词： selectivity hydrogenation acetylene ethylene palladium

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Radiological characterization of building materials used in Malaysia and assessment of external and internal doses

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Nuclear Science and Techniques 2019年第3期30卷 82-96页

作者： shittu Abdullahi Aznan Fazli Ismail Supian Samat Nuclear Science Program Faculty of Science and Technology Universiti Kebangsaan Malaysia (UKM) Department of Physics Faculty of Science Gombe State University Centre for Frontier Science Faculty of Science and Technology Universiti Kebangsaan Malaysia (UKM)

In this study, the activity concentrations of ^(226)Ra,^(232)Th,^(222)Rn, and ^(40)K, emanation fractions(P),equilibrium equivalent concentration(EEC), and mass exhalation rates(E_m) of radon released from building materials used in Malaysia were studied using gamma-ray spectrometer with HPGe detector. Radiological parameters[activity concentration index(ACI), indoor air-absorbed dose rate(D_(in)), annual effective dose(AED_(in)) from external and internal(E_(Rn)), soft tissues(H_(ST)) and lung(H_L), and effective dose equivalent(H_(eff))] were estimated to evaluate radiological hazards due to the use of these building materials: sand, cement, gravel, bricks, tiles, fly ash, white cement, and ceramic raw materials. The measured P, EEC,and E_m vary from 10 to 30%, 0.9 to 22 Bq m^(-3), and 33 to 674 mBq h^(-1) kg^(-1), respectively, while the calculated ACI and AED_(in) vary from 0.1 ± 0.01 to 2.1 ± 0.1 and 0.1 ± 0.01 to 2.4 ± 0.6 mSv y^(-1), respectively. On the other hand, the internal annual effective dose ranges from 0.1 to 1.4 mSv y^(-1). The estimated radiological risk parameters were below the recommended maximum values, and radiological hazards associated with building materials under investigation are therefore negligible.

关键词： Indoor radon Emanation fraction Equilibrium equivalent concentration Mass exhalation rate Annual effective dose Effective dose equivalent

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Land tenure security,place satisfaction and loyalty in the peri-urban area of Ibadan City,Nigeria

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Regional Sustainability 2022年第4期3卷 346-355页

作者： Taiwo oladapo BABALOLA Institute of Governance Humanitiesand Social SciencesPan African UniversityYaoundé06000Cameroon

Land tenure security is pertinent to achieving the sustainable development agenda in cities where land is needed and useful for development *** empirical research has been done to prove the importance of tenure security for investment,resilience,conservation,food security,as well as health and well-being,but it has not been clarified if and how land tenure security could adequately influence place loyalty and satisfaction with the residential environment,as it is clear that place loyalty and satisfaction are pertinent to inclusive *** the case of Ibadan City,the study examined how different dimensions of tenure security could determine residents’place loyalty and *** study employed a survey cross-sectional research design to distribute 514 structured questionnaires to household heads across 4 sampled peri-urban local government areas while 452 were retrieved for *** regression analysis model was employed to understand the association between tenure security dimensions and satisfaction(as model I)and loyalty(as model II).For model I,F=8.640,P=0.000,R=0.555,and R^(2)=0.308 were obtained;while for model II,F=9.157,P=0.001,R=0.415,and R^(2)=0.173 were *** thus means that residents’place loyalty and satisfaction can partly be explained by tenure *** particular,respondents with no eviction experience,recognized property rights,and invulnerable to eviction have higher odds of being satisfied and ***,we recommend protection,improvement,and upgrading of land tenure security as one of the means to promote place loyalty and satisfaction,which is essential to achieving inclusive and sustainable development.

关键词： Land tenure security Place satisfaction Place loyalty Urban governance Peri-urban area Sustainability African city

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Machine learning for advanced energy materials

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Energy and AI 2021年第1期3卷 22-48页

作者： Yun Liu oladapo Christopher Esan Zhefei Pan Liang An Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARChina

The screening of advanced materials coupled with the modeling of their quantitative structural-activity relation-ships has recently become one of the hot and trending topics in energy materials due to the diverse challenges,including low success probabilities,high time consumption,and high computational cost associated with the traditional methods of developing energy *** this,new research concepts and technologies to promote the research and development of energy materials become *** latest advancements in ar-tificial intelligence and machine learning have therefore increased the expectation that data-driven materials science would revolutionize scientific discoveries towards providing new paradigms for the development of en-ergy ***,the current advances in data-driven materials engineering also demonstrate that the application of machine learning technology would not only significantly facilitate the design and development of advanced energy materials but also enhance their discovery and *** this article,the importance and necessity of developing new energy materials towards contributing to the global carbon neutrality are presented.A comprehensive introduction to the fundamentals of machine learning is also provided,including open-source databases,feature engineering,machine learning algorithms,and analysis of machine learning ***,the latest progress in data-driven materials science and engineering,including alkaline ion battery materials,pho-tovoltaic materials,catalytic materials,and carbon dioxide capture materials,is ***,relevant clues to the successful applications of machine learning and the remaining challenges towards the development of advanced energy materials are highlighted.

关键词： Energy materials Artificial intelligence Machine learning Data-driven materials science and engineering Prediction of materials properties Design and discovery of energy materials

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