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Open Journal of Nursing 2013年第1期3卷 122-129页

作者： Tomoko Takeuchi Taisuke Togari Makoto oe.Yukie Takemura Hiromi Sanada Faculty of Liberal Arts The Open University of Japan Chiba Japan Faculty of Nursing Tokyo Healthcare University Tokyo Japan graduate School of Medicine The University of Tokyo Tokyo Japan Research Hospital The Institute of Medical Science The University of Tokyo Tokyo Japan

The current research conducted a longitudinal study of new graduate nurses at 3 times-prior to their employment as nurses and 3 months and 1 year afterward. This study yielded 3 findings. 1) The mental health of new graduate nurses significantly worsens 3 months after employment as a nurse and mental health 1 year after employment as a nurse was significantly worse than that before employment. 2) A sense of coherence (SOC) is the ability to cope with stressors, and the 3 components of SOC decreased significantly in the year after employment as a nurse. 3) The mental health of new graduate nurses was significantly affected by a low SOC and by previous diminishing of SOC. Findings suggested the importance of support to sustain and improve the mental health of new graduate nurses and the importance of approaches in the workplace to encourage the development of SOC.

关键词： Longitudinal Study Mental Health New graduate Nurses Sense of Coherence (SOC)

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利用复合电析装置降低电极消耗

重特技术 1990年第1期 51-56页

作者： Prenn,oe

Three-Component Coupling Catalyzed by Phosphine: Preparation of α-Amino γ-Oxo Acid Derivatives

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International Journal of Organic Chemistry 2012年第2期2卷 111-116页

作者： Yohei oe.Takeshi Inoue Hiroaki Kishimoto Mitsuhiro Sasaki Tetsuo Ohta Isao Furukawa Department of Biomedical Information Faculty of Life and Medical Sciences Doshisha University Kyotanabe Kyoto 610-0394 Japan Department of Biomedical Information Faculty of Life and Medical Sciences Doshisha University Kyotanabe Kyoto 610-0394 Japan Department of Molecular Science and Technology Faculty of Engineering Doshisha University Kyotanabe Kyoto 610-0394 Japan Department of Molecular Science and Technology Faculty of Engineering Doshisha University Kyotanabe Kyoto 610-0394 Japan

The three-component coupling reaction of ethyl propiolate (1), phthalimide (2), and aldehyde (3) catalyzed by tripheny- lphosphine, was developed. A solution of an equivalent amount of 1 and 2 in benzaldehyde (3a) in the presence of 30 mol% of PPh3 was heated at 100?C for 48 h to give N-(1-ethoxycarbonyl-3-oxo-3-phenylpropyl)phthalimide (4a) in 83% yield. This reaction was thought to proceed via vinylphosphonium salt formed from the reaction of ethyl propiolate (1) with triphenylphosphine in situ.

关键词： Three-Component Coupling Phosphine 2-Amino-4-Oxocarboxylic Acid

Silicon-based microe.ectrode arrays for stimulation and signal recording of in vitro cultured neurons

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Science China(Information Sciences) 2011年第10期54卷 2199-2208页

作者： PAN HaiXian 1,L XiaoYing 1 ,WANg Zhigong 2,REN TianLing 3,FANg Tao 1,ZHANg Jie 1,ZHOU ChangJian 3 & WANg Ligang 3 1 State Key Laboratory of Bioe.ectronics,Southeast University,Nanjing 210096,China 2 Institute of RF-& oe.ICs,Southeast University,Nanjing 210096,China 3 Institute of Microe.ectronics,Tsinghua University,Beijing 100084,China 1. State Key Laboratory of Bioe.ectronics Southeast University Nanjing 210096 China2. Institute of RF-& OE-ICs Southeast University Nanjing 210096 China3. Institute of Microelectronics Tsinghua University Beijing 100084 China

Microe.ectrode arrays (MEAs) for stimulation and signal recording of in vitro cultured neurons are *** MEA is composed of 60 independent electrodes with 59 working ones and one reference *** electrodes are divided into 30 *** each pair of electrodes,four independent states can be realized to define the accessing modes of neurons cultured on the surface of the electrodes.A total MEA covers an area of 10 mm×10 *** are fabricated in a silicon-based semiconductor *** implemented MEA is bonded on a specially designed printed-circuit-board (PCB) and surrounded by a culture *** impedance measurement has been made to verify the electrical characteristics of *** surface was modified to enhance the biocompatibility.A series of PC12 cells culture experiments validates the effectiveness of the *** extracellular signal recording experiment with acetylcholine (Ach) as a stimulant has been carried out,and the results show the feasibility of MEAs for extracellular action potential *** electrical stimulation and recording experiments have been carried out *** indicate that MEAs can be used for extracellular stimulation,recording,simultaneous stimulation and recording,and isolation of PC12 cells network cultured in vitro.

关键词： microe.ectrode arrays (MEAs) extracellular recording stimulation and recording neurons net-work in vitro

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高强度混凝土轻质骨料的特性

电子建设科技情报 1992年第1期 13-22页

作者： gjoe.,oe.卓华

用溅射的SiO2膜作为锌扩散掩模制作gaInAsP/InP平面条形激光器

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微纳电子技术 1981年第2期 71-79页

作者： Kunishige oe.姚晓峨

本文研究了用溅射的 SiO2膜作为锌扩散掩模制作的 gaInAsP/InP 双异质结平面条形激光器的激射特性对条宽的依赖关系。条宽10、15、20μm的激光器以基模模式工作,每面微分量子效率大于20%,而条宽5μm 的激光器即使正好在阈值以上也以多... 详细信息

本文研究了用溅射的 SiO2膜作为锌扩散掩模制作的 gaInAsP/InP 双异质结平面条形激光器的激射特性对条宽的依赖关系。条宽10、15、20μm的激光器以基模模式工作,每面微分量子效率大于20%,而条宽5μm 的激光器即使正好在阈值以上也以多横模工作。而且条宽5μm 激光器的阈值电流大大增加,与条宽较大的条形激光器相比,其激射波长向更短的波长漂移。条宽15μm 的激光器显示出良好的模式特性,直到输出功率为每面22mW 时仍都以基横模工作,而且在较宽的电流范围内以单纵模工作。本文讨论了这种激射特性对条宽依赖关系的形成原因,并且假设用溅射的 SiO2作掩模进行条区锌扩散是造成这种依赖关系的主要原因。

关键词：激光器输出功率双异质结光激射器电子器件激射波长溅射真空沉积

gluconacetobacter hansenii gK-1 Ingestion for 8 Weeks Improves Skin Discomfort in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study

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Food and Nutrition Sciences 2024年第11期15卷 1085-1094页

作者： Mariko oe.Mengwei Yuan Keiko Kuriyama Yumi Takeda Mamoru Kimura Ryosuke Matsuoka Naoki Miura Jun Muto R&D Division Kewpie Corporation Tokyo Japan Miura Medical Clinic Osaka Japan Department of Dermatology Graduate School of Medicine Ehime University Toon Japan

gluconacetobacter hansenii gK-1 is an acid-resistant gram-negative bacterium used in vinegar brewing. Oral ingestion of gK-1 was previously reported to help maintain immunity and reduce nasal discomfort. Considering the suggested mechanism of action of activation of regulatory T cells via TLR4 to control Th1/Th2 balancing, gK-1 is also assumed to reduce skin discomfort secondary to immune reactions;however, this has not been validated in humans. Thus, we conducted a randomized, double-blind, placebo-controlled, parallel-group study on 100 healthy Japanese men and women (mean age, 47.6 ± 1.01 years) aged 20–64 years who consumed gK-1 (9 × 109 cells) daily for 8 weeks. Visual analog scale for overall, facial, arm, and leg skin discomfort was assessed before and after ingestion. The cumulative days of skin discomfort during the ingestion period were assessed. Compared with the placebo group, the g. hansenii gK-1 group had a significantly lower visual analog scale for overall and facial skin discomfort after 8 weeks and cumulative days of skin discomfort. Moreover, there were no adverse events attributable to g. hansenii gK-1. This study confirmed that oral ingestion of g. hansenii gK-1 contributed to skin integrity. The study protocol was preregistered at the Clinical Trials Registry System (registration no. UMIN000053005, December 7, 2023).

关键词： Acetic Acid Bacteria Ingestion Skin Itch Paraprobiotics Functional Food

A 9.95-11.5gb/s Full Rate CDR with Jitter Attenuation Pll in 65-nm CMOS Technology

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A 9.95-11.5Gb/s Full Rate CDR with Jitter Attenuation PLL in...

An Efficient Synthesis of 2,3-Diaminoacid Derivatives Using Phosphine Catalyst

2011 IEEE 13th International Conference on Communication Technology(ICCT 2011)

作者： Xuehui Chen Yingmei Chen Institute of RF-& oe.ICs Southeast University 210096 Nanjing China

A Pll based clock and data recovery （CDR） circuit aided with jitter attenuation Pll using 65-nm CMOS technology is presented in this *** CDR employs a dual-loop architecture where the frequency-locked loop acts as an acquisition aid to the phase-locked *** two loops share the charge-pump （CP）,the LC voltage-controlled oscillator （VCO） and the loop filter through a multiplexer （MUX） and a lock detector （LD）.An additional jitter attenuation Pll is used to simultaneously meet jitter tolerance and jitter transfer specifications defined in g.8251 of optical transport network （ITU-T OTN）.The simulation results show that the peak-to-peak jitter of the recovered clock and data is 5.17ps and is 2.3ps *** core of the whole chip consumes 72mA current from a 1.0V supply.

关键词： CDR jitter g.8251 frequency-locked loop phase locked loops

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International Journal of Organic Chemistry 2014年第3期4卷 189-194页

作者： Yohei oe.Hiroaki Kishimoto Nahoko Sugioka Daisuke Harada Yukio Sato Tetsuo Ohta Isao Furukawa Department of Biomedical Information Faculty of Life and Medical Sciences Doshisha University Kyoto Japan Department of Molecular Science and Technology Faculty of Engineering Doshisha University Kyoto Japan

Ethyl 2,3-diphthalimidoylpropanoate was effectively synthesized from ethyl propynoate with two equivalents of phthalimide catalyzed by triphenylphosphine in good yield. The choice of reaction media was important for selective synthesis of the desired 2,3-diaminocarboxylic acid derivatives. The reaction is considered to occur through a zwitterionic intermediate derived from the reaction of the α,β-unsaturated ester with triphenylphosphine.

关键词： Addition Alkynes Amino Acids Catalysis Multi-Component Reaction

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目标定向多普勒雷达装置

贵州航天 1995年第2期 4-10页

作者：董真 Ritt.,oe