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21st IUBMB and 12th FAoBMB International Congress of Biochemistry and Molecular Biology

作者： Rana Rohini Aiguel Yilmaz simpson j Pete Matthews j Steve Spear Abigall Atkins Heien Byme Bernadette Imperial College London UK

＜正＞Recognition of highly specific pathogen-associated molecular patterns by Toll-like receptors（TLRs） initiates innate *** intracellular Toll/ Interleukin-1（TIR） domain of TLRs,is responsible for recruitment of downstream adapter proteins through homotypic TIR-TIR interactions that initiates the signaling cascade,culminating in proinflammatory ***-like proteins from pathogenic bacteria have been implicated to inhibit upregu-

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石灰性稻田土壤上化肥氮损失的研究

土壤学报 1989年第4期26卷 337-343页

作者：朱兆良 j.R.simpson 张绍林蔡贵信陈德立 j.R.Freney A.V.jackson 中国科学院南京土壤研究所 Division of Plant Industry CSIRO Canberra Australia. Division of Environmental Mechanics CSIRO Canberra Australia.

在田间用^(15)N示踪技术和微气象学的质量平衡法研究了石灰性稻田土壤上化肥氮的损失。结果表明:(1)碳铵和尿素在有水层下混施作基肥,氮素总损失分别高达72%和63%;其中氨挥发达到39%和30%,分别占总损失的54%和48%;都远高于以往在中性水... 详细信息

在田间用^(15)N示踪技术和微气象学的质量平衡法研究了石灰性稻田土壤上化肥氮的损失。结果表明:(1)碳铵和尿素在有水层下混施作基肥,氮素总损失分别高达72%和63%;其中氨挥发达到39%和30%,分别占总损失的54%和48%;都远高于以往在中性水稻土区酸性土壤上测得的结果。(2)石灰性稻田土壤氨挥发量大,是造成其氮素总损失远高于酸性稻田土壤的根本原因。两种土壤上,氮肥的反硝化损失量(差减法)似没有明显的差异。(3)石灰性土壤上氨挥发量大的主要原因是其高的土壤和灌溉水的pH。石灰性土壤的高pH和光照充足,促进了田面水中藻类的生长。由此引起的日间田面水pH的上升促进了尿素的氨挥发,而对碳铵的氨挥发的促进则不大。

关键词：石灰性土壤稻田化肥氮

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不同原棉和不同梳棉机加工的条子喂入不同气流纺纱机的比较

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国外纺织技术(纺织分册) 1984年第10期 11-15页

作者： j.simpson 周开宇

引言最初用于棉纺的气流纺纱机是无除杂装置的。由于纺纱杯内积杂,就必需使用非常洁净的原棉或者采用双联梳棉这类的棉条准备工序。第二代的气流纺纱机在开松辊或分梳辊部分加装了除杂装置。而且,也改进了纺纱杯的设计以最大限度地减... 详细信息

引言最初用于棉纺的气流纺纱机是无除杂装置的。由于纺纱杯内积杂,就必需使用非常洁净的原棉或者采用双联梳棉这类的棉条准备工序。第二代的气流纺纱机在开松辊或分梳辊部分加装了除杂装置。而且,也改进了纺纱杯的设计以最大限度地减少积杂。最新型的气流纺纱机能令人满意地加工含杂很多的棉条;但是,在确定开清棉、梳棉和纺纱

关键词：除杂装置开清棉分梳辊纺纱杯捻系数棉箱环锭纺纱机梳棉工序熟条均匀度试验仪

开清棉和梳棉的除杂作用对气流纺纱杯积杂的影响

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国外纺织技术 1981年第35期 2-6页

作者： j.simpson 朱德明

引言排除杂质,气流纺纱比环锭纺纱更加重要。因而,对于气流纺纱,开清棉除杂作用要加强,尤其要去除细小尘杂,还有在给棉罗拉与纺纱杯之间大多数气流纺机已经组合成刺辊型除杂器。梳理和除杂作用极好的双

关键词：纺纱杯机器纺织机械零部件除杂纺纱工艺开清棉气流纺机梳棉排杂原棉气流纺纱机转杯纺纱机纺纱机械批号生条定向度

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土壤中的反硝化作用和缔合氮的转化

河南大学学报(自然科学版) 1977年 73-79页

作者： George Stanford ,j.o.Legg ,Stanislaw Dzienia ,E.C.simpson,jr. ,王庭梧 ,王德甫

目前普遍认为,由于土壤中的生物反硝化作用,导致差不多所有的硝酸根都转变成了氮气和一氧化二氮（威勒与德威奇1954,诺密克1956,布伦纳与肖氏1958,卡迪与巴塞洛缪1960,库珀与史密斯1963）。相反,麦克雷等人（1968）发现,施加于四种菲律... 详细信息

目前普遍认为,由于土壤中的生物反硝化作用,导致差不多所有的硝酸根都转变成了氮气和一氧化二氮（威勒与德威奇1954,诺密克1956,布伦纳与肖氏1958,卡迪与巴塞洛缪1960,库珀与史密斯1963）。相反,麦克雷等人（1968）发现,施加于四种菲律宾洪积土壤中的K15No3,6星期后有4.5～39％转变成了有机N。在使用15No3-的研究中,以往都没有检测到15N示踪的NH1+（威勒和德威奇1954;诺密克1956;布伦纳与肖氏1958;麦克雷等人1968）。

关键词：异化作用蒂姆克兰分解代谢反硝化作用硝酸根气态产物反硝化微生物右旋糖己糖葡萄糖 NH

Everything you always wanted to know about metallic hydrogen but were afraid to ask

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Matter and Radiation at Extremes 2020年第3期5卷 25-30页

作者： Eugene Gregoryanz Cheng ji Philip Dalladay-simpson Bing Li Ross T.Howie Ho-Kwang Mao Centre for Science at Extreme Conditions and School of Physics and Astronomy University of EdinburghEdinburgh EH93FDUnited Kingdom Center for High Pressure Science and Technology Advanced Research Shanghai 201203China Key Laboratory of Materials Physics Institute of Solid State PhysicsChinese Academy of SciencesHefei 230031China

The hydrogen molecule is made from the first and lightest element in the periodic *** hydrogen gas is either compressed or cooled,it forms the simplest molecular *** solid exhibits many interesting and fundamental physical *** is believed that if the density of the solid is increased by compressing it to very high pressures,hydrogen will transform into the lightest known metal with very unusual and fascinating properties,such as room temperature superconductivity and/or *** this article,we provide a critical look at the numerous claims of hydrogen metallization and the current experimental state of affairs.

关键词： hydrogen metallic solid

Evaluation of Real-Time 16S rDNA PCR and Pyrosequencing for Routine Identification of Bacteria in joint Fluid and Tissue Specimens

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open journal of Medical Microbiology 2011年第1期1卷 1-6页

作者： Naomi j. Gadsby Alev onen Sally-Anne Phillips Luke Tysall Steffen j. Breusch Hamish simpson jayshree Dave Elzbieta Czarniak Kate E. Templeton 不详

16S rDNA PCR and sequencing are powerful tools for bacterial detection and identification, although their routine use is not currently widespread in the field of clinical microbiology. The availability of pyrosequencing now makes 16S rDNA assays more accessible to routine diagnostic laboratories, but this approach has had limited evaluation in general diagnostic practice. In this study we evaluated a real-time 16S rDNA PCR and pyrosequencing assay for use in a routine microbiology laboratory, by retrospectively testing joint fluid and joint tissue specimens received for conventional culture. We found that use of the real-time 16S rDNA assay was clinically valuable in this specimen type because it enabled us to identify a small number of culture-negative infections. Although faster and less labour-intensive, we found that the utility of pyrosequencing for pathogen identification is still hampered by shorter read lengths compared to conventional (Sanger) sequencing. Combining results from both molecular and conventional culture methods, bacteria were only detected in 11.8% specimens in this study. However, the detection rate was increased to 18.6% if specimens were only included from patients with a documented clinical suspicion of infection. In conclusion, while pyrosequencing had significant advantages in speed and ease-of-use over conventional sequencing, multiple reactions will be required to deliver comparable species-level identification, thus negating many of the benefits of using the technique. We found that 16S rDNA PCR and sequencing should be rationally targeted on the basis of good clinical information in the routine diagnostic setting, and not used as a general screening test for the exclusion of bacterial infection in joint specimens.

关键词： 16S rRNA Real-Time PCR Sequencing Pyrosequencing orthopaedic Infection

天然变形的深变质长英质岩石中相边界的活动性:扩散蠕变的证据

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地质科学译丛 1993年第1期10卷 17-23页

作者： Robert j.W.Gower Carol simpson 宋媛 Department of Earth and Planetary Sciences the Johns Hopkins University Baltimore MD21218 USA

引言显微构造分析的目的之一,是辨别在变形时或其后控制岩石的相和颗粒边界的形成和运动的颗粒尺度的过程.同构造的颗粒边界运动或动态结晶的结构证据已在实验和天然变形的矿物中认出.一般认为这种重结晶是一个守恒过程,通过材料单矿物... 详细信息

引言显微构造分析的目的之一,是辨别在变形时或其后控制岩石的相和颗粒边界的形成和运动的颗粒尺度的过程.同构造的颗粒边界运动或动态结晶的结构证据已在实验和天然变形的矿物中认出.一般认为这种重结晶是一个守恒过程,通过材料单矿物区的颗粒边界的形成和迁移在化学成分和晶体构造方面仅有轻微的变化.但是,地球化学研究表明,在许多天然变形中,化学引起的物质转移是普遍的.它将会造成颗粒形态组构,这不仅是等化学的动态重结晶,而且也是由于颗粒尺度的反应和扩散所造成的.

关键词：长英质岩石深变质相边界蠕变

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Extremely low-volume, high-intensity interval training improves exercise capacity and increases mitochondrial protein content in human skeletal muscle

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open journal of Molecular and Integrative Physiology 2013年第4期3卷 202-210页

作者： jasmin K. Ma Trisha D. Scribbans Brittany A. Edgett j. Colin Boyd Craig A. simpson jonathan P. Little Brendon j. Gurd Department of Emergency Medicine Kingston General Hospital Kingston Canada Department of Health and Social Development University of British Columbia Okanagan Kelowna Canada Department of Kinesiology Queen’s University Kingston Canada

Purpose: The purpose of the present study was to evaluate whole-muscle content of several proteins involved in the regulation of skeletal muscle mitochondrial protein content and anaerobic capacity following 4 weeks of extremely low-volume high-intensity interval training (HIT). Methods: Young, healthy, recreationally active adult males (n = 8) trained 4 times a week for 4 weeks on a cycle ergometer. Each session involved 4 min of total exercise comprised of eight 20 s intervals at ~170% of peak aerobic power separated by 10 s rest. Muscle biopsies were taken prior to (pre) and ~72 hrs post-training (post). Par- ticipants completed an incremental peak oxygen up- take (Vo2peak) test and a Wingate test pre-, mid-, and post-training. Results: Vo2peak was elevated (p p ost-training (pre: 40.5 ± 3.8 ml·kg-1·min-1, mid: 43.4 ± 2.5 ml·kg-1·min-1, post-: 47.2 ± 2.9 ml·kg-1·min-1). Wingate mean power also increased with training (pre-: 701.0 ± 73.0 W, mid-: 745.5 ± 73.3 W, post-: 786.8 ± 80.0 W). While maximal citrate synthase activity was unchanged, protein expression of the mitochondrial protein cytochrome c oxidase (CoX) subunit I (+27%;p p p = 0.08) increased. Increases (p α (+19%), and nuclear PGC-1α (+46%) were also observed after 4 weeks of HIT. No changes were observed in the whole-muscle contents of PDHe1a, PDK4, SIRT1, mToR, S6K1, MCT1, or PFK protein. Conclusions: These results demonstrate that several mitochondrial protein (but not citrate synthase activity), PGC-1α protein content, and exercise capacity can be improved in only 4 min of total training time per day, 4 days per wk using HIT cycle training.

关键词： PGC-1α Mitochondrial Biogenesis High-Intensity Interval Training SIRT1 Aerobic Fitness