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CARDIoRESPIRAToRY EFFECTS oF LA- TANoPRoST AND BETAXoLoL IN PA-TIENTS WITH PRIMARY oPEN ANGLE GLAUCoMA

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国际眼科杂志 2003年第1期3卷 37-38页

作者： E.F.Erkin P.Celik o.kayikcioglu H.Deveci A.Sakar Faculty of Medicine Celal Bayar University TurkeyFaculty of Medicine Celal Bayar University TurkeyFaculty of Medicine Celal Bayar University TurkeyFaculty of Medicine Celal Bayar University TurkeyFaculty of Medicine Celal Bayar University Turkey

Purpose: The assess cardiorespiratory changes in primary open angle glaucoma (PoAG) palients using latanoprost or betaxoloL Methods: Thirty newly diagnosed PoAG patients without any systemic diseases were randomly div... 详细信息

关键词：原发性开角型青光眼患者拉担前列素倍他洛尔药理作用心肺功能

CoMPARISoN oF SELF -INSTILLATIoN FRoM MULTI-DoSE AND SINGLE DoSE EYE DRoP BoTTLES IN ELDERLY PA-TIENTS

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国际眼科杂志 2003年第1期3卷 57-57页

作者： o.kayikcioglu T.Erakagun S.Egilmez C.Akkin Department of ophthalmology Faculty of Medicine Celal Bayar UniversityDepartment of Ophthalmology Fac-ulty of Medicine Ege University TurkeyDepartment of Ophthalmology Fac-ulty of Medicine Ege University TurkeyDepartment of Ophthalmology Fac-ulty of Medicine Ege University Turkey

Purpose: To determine the location of self-intilled eye drops from single-dose and multi-dose dispensers in the elderly patients. Methods: Location of self-instilled eye drops of 60 elderly (age 61.6±8.9) and 60 young patients (age 22.4±2.6) from a multi-dose and single dose eye-drop bottle was determined and scored on a transparent schema alligned over the eye during instillation. Results: The right eye scores were significantly

关键词：青光眼老年患者多剂量滴瓶单剂量滴瓶眼药水自行滴注比较研究

Prognostic value of claudin 18.2 expression in gastric adenocarcinoma

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World Journal of Gastrointestinal oncology 2023年第2期15卷 343-351页

作者： Erkan kayikcioglu Ramazan oğuz Yüceer Bulent Cetin Kamuran Yüceer Nermin Karahan Department of Medical oncology Suleyman Demirel UniversityIsparta 32260Turkey Department of Pathology Isparta City HospitalIsparta 32360Turkey Department of Internal Medicine Suleyman Demirel UniversityFaculty of MedicineIsparta 32360Turkey Department of Pathology Suleyman Demirel UniversityIsparta 32360Turkey

BACKGRoUND Claudin 18.2(CLDN18.2)is a cell surface protein expressed by gastric cancer *** monoclonal antibody zolbetuximab binds CLDN18.2-positive cancer cells and causes cancer cell death.A few studies researched the prognostic effect of CLDN18.2 expression in metastatic gastric *** To identify the prognostic value of CLDN18.2 expression in patients with metastatic gastric *** This study was conducted with 65 patients over the age of 18 who were diagnosed with metastatic gastric *** investigated the effect of CLDN18.2 expression on clinicopathological characteristics(age,sex,histological grade,Lauren classification,family history,metastatic site,HER2 expression)and prognosis for patients with metastatic gastric *** CLDN18.2 expression was positive in 73.8%(48)of the *** the median 17.7-mo follow-up period,89.2%(58)of the patients *** progression-free survival and overall survival(oS)were 6 mo(95%confidence interval:1.6-10.4)and 12 mo(95%confidence interval:7.5-16.5).There was no statistically significant correlation between CLDN18.2 expression and clinicopathological characteristics of the *** univariate and multivariate Cox regression analysis,there was no correlation between clinicopathological characteristics of patients and progression-free survival or *** CLDN18.2 expression was quite high in patients with gastric adenocarcinoma,identifying the proportion of the patients in whom zolbetuximab would be *** is no statistically significant correlation with clinicopathological characteristics and ***18.2 is not a prognostic marker in patients with gastric adenocarcinoma,although it is predictive.

关键词： Gastric adenocarcinoma Claudin 18.2 overall survival Clinicopathological characteristics

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女性生殖道放线菌感染

世界核心医学期刊文摘（妇产科学分册） 2005年第5期1卷 18-18页

作者： kayikcioglu F Akif Akgul M Haberal A Faruk Demir o 张虹 Department of Gynecology SSK Ankara Matern. Women’s Hlth. T. Etlik TR06010 Ankara Turkey

objectives: To analyze clinical and laboratory characteristics of patients wit h pelvic actinomyces. Study design: We studied five patients with pelvic actinom yces who were admitted between January 1, 2002 and December 31,2002. The initial complaints, diagnostic methods, therapeutic alternatives and results of the the rapies were examined. Results: The ages of the cases varied between 32 and 52 ye ars old. All five patients had been using an intrauterine device. Three cases ha d hydronephrosis due to infection. Two patients were diagnosed postoperatively w hile the other three cases were diagnosed with cervical smear and endometrial bi opsy; penicillin G was administered to all. The patients are still under surveil lance, and without any problems. Conclusion: In patients with an intrauterine de vice, actinomyces should be remembered in differential diagnosis of pelvic infec tions. Preoperative diagnosis is of the utmost importance in order to prevent mo rbidity of this infiltrative infection. Longterm penicillin therapy proved to be successful. Complicated or resistant cases to medical therapy should be candida tes for surgical therapy.

关键词：放线菌感染盆腔感染侵袭性感染子宫内膜活检宫内节育器宫颈涂片肾盂积水鉴别诊断研究设计诊断方法