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Psychopathological outcomes and defence mechanisms in clinically healed adults with a paediatric cancer history: an exploratory study

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General Psychiatry 2021年第4期34卷 60-68页

作者： Antonino Petralia Emanuele Bisso Ilaria Concas Antonino Maglitto nunzio bucolo Salvatore Alaimo Andrea Di Cataldo Maria Salvina Signorelli Alfredo Pulvirenti Eugenio Aguglia Department of Clinical and Experimental Medicine Psychiatry UnitUniversity of CataniaSchool of MedicineCataniaItaly Department of Mathematics and Computer Science University of CataniaCataniaItaly Department of Clinical and Experimental Medicine Pediatric Hemato-Oncology UnitUniversity of CataniaSchool of MedicineCataniaItaly

Background The incidence of paediatric cancers has increased in recent years;however,with advances in the treatment of paediatric cancer,almost 80%of children and adolescents who receive a diagnosis of cancer become long-term *** the high stress levels associated with cancer,it becomes important to ascertain the risk and likelihood of psychiatric disorders in adult paediatric cancer *** This study aims to investigate the relationship between defence styles and predisposition to psychiatric diseases in adults with a history of paediatric *** We performed an explorative study on a sample of 66 clinically healed adults with a history of paediatric cancer(survivors)during follow-up visits at the University Hospital‘Policlinico G Rodolico’of Catania(Italy)and 98 healthy controls among medicine *** administered the Defence Mechanism Inventory(DMI)to assess defence *** Symptom Checklist-90-Revised(SCL-90-R)and the Davidson Trauma Scale(DTS)were administered to assess psychopathological *** conducted comprehensive statistical analysis based on correlation analysis and mediation analysis to investigate the relationship between defence styles and psychopathological outcomes in survivors compared with *** The survivors obtained statistically significant lower values in TAO,PRO and TAS defence styles and a higher value in *** groups showed non-pathlogical mean scores in DTS and SCL-90-R(with an exception of the obsessive-compulsive subscale),with lower mean values among *** results of mediation analysis showed that TAS had mediation effects on interpersonal sensitivity,anxiety,PSDI,GSI and avoidance,while TAO had mediation effects on DTS total score and ***,for these psychopathological indices,the effect of the oncological pathology was indirect and mediated by TAO or *** analysis exlcluded mediation effects between the remaining variables and defence *** Integrati

关键词： clinically pathological TAO

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