This study was undertaken to examine the applicability of the SWAT model in Gumera river basin upstream of Lake Tana, Ethiopia for simulating stream runoff and sediment load. The area of river basin was discretized in...
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This study was undertaken to examine the applicability of the SWAT model in Gumera river basin upstream of Lake Tana, Ethiopia for simulating stream runoff and sediment load. The area of river basin was discretized into 24 sub-catchments using ArcSWAT interface of the model. The semi automated Sequential Uncertainty Fitting (SUFI2) and fully automated Parameter Solution (ParaSol) calibration process built in SWAT calibration and uncertainty program (SWAT-CUP) were used to calibrate the model parameters using time series of flow and sediment load data of 1994 to 2002 and validated with the observed data from years 2003 to 2006. The performance of the model was evaluated using statistical and graphical methods to assess the capability of the model in simulating the runoff and sediment yield for the study area. The coefficient of determination (R2) and nse values for the daily runoff by using [ParaSol] optimization technique was obtained as 0.72 and 0.71 respectively for the calibration period and 0.79 and 0.78 respectively for the validation period, R2 and nse values of monthly flow calibration using SUFI2 are 0.83 and 0.78 respectively for validation it was 0.93 and 0.93. For monthly sediment yield by using SUFI2 calibration technique the model evaluation coefficients R2 and NS for calibration was computed as 0.61 and 0.60 respectively, for validation it was 0.84 and 0.83 respectively. The sensitivity analysis on 13 runoff producing parameters was also carried out and discussed.
In verifying antiretroviral efficacy of a Nigerian broad spectrum antiviral medicine (Antivirt®), the Nigerian Institute of Medical Research certified it safe by toxicological test on laboratory animals, before commen...
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In verifying antiretroviral efficacy of a Nigerian broad spectrum antiviral medicine (Antivirt®), the Nigerian Institute of Medical Research certified it safe by toxicological test on laboratory animals, before commencing treatment of three HIV/AIDS patients whose viral loads varied widely (millions, hundreds of thousands and thousands). To overcome errors associated with such wide differences in subject-classes, percentages of viral load-reductions were calculated instead of comparing their viral loads. After first month of the Antivirt®-treatment, means of ranked viral loads of the patients significantly (P ≤ 0.05) increased from 10.00 ± 7.21 to 11.30 ± 5.51 (-41.03% infection-reduction rate) instead of reducing. From second month of the trial, their viral loads started to reduce, continuously, so that their infection-reduction rates have been increasing from that -41.03%, to -38.22% in the second month;23.98% in the third month;31.76% in the fourth month and 64.12% after the fifth month.
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