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Hierarchical structures hydrogel evaporator and superhydrophilic water collect device for efficient solar steam evaporation

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Nano Research 2021年第4期14卷 1135-1140页

作者： Wenwei Lei Sovann Khan Lie Chen norihiro Suzuki Chiaki Terashima Kesong Liu Akira Fujishima Mingjie Liu Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China Photocatalysis International Research Center Tokyo University of Science2641 YamazakiNodaChiba 278-8510Japan

Efficient light absorption and trapping are of vital importance for the solar water evaporation by hydrogel-based photothermal conversion *** strategies are focused on the development of the composition and structure of the hydrogers internal *** our point of view,the importance of the surface structure of hydrogel has usually been underestimated or *** inspired by the excellent absorbance and water transportation ability of biological surface structure,the hierarchical structured hydrogel evaporators(HSEs)increased the light absorption,trapping,water transportation and water-air interface,which is the beneficial photothermal conversion and water *** HSEs showed a rapid evaporation rate of 1.77 kg·m^(-2)·h^(-1)at about 92%energy efficiency under one sun(1 kW·m^(-2)).Furthermore,the superhydrophilic window device was used in this work to collect the condensed water,which avoids the light-blocking caused by the water mist formed by the small droplets and the problem of the droplets stick on the device dropping back to the bulk *** with the excellent photothermal conversion hydrogel and superhydrophilic window equipment,this work provides efficient evaporation and desalination of hydrogel-based solar evaporators in practical large-scale applications.

关键词： light-trapping large-scale hierarchical structure hydrogel evaporator solar steam evaporation superhydrophilic window

Mechanical properties of nerve roots and rami radiculares isolated from fresh pig spinal cords

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Neural Regeneration Research 2015年第11期10卷 1869-1873页

作者： norihiro Nishida Tsukasa Kanchiku Junji Ohgi Kazuhiko Ichihara Xian Chen Toshihiko Taguchi Department of Orthopedic Surgery Yamaguchi University Graduate School of Medicine Faculty of Engineering Yamaguchi University Non-Profit Organization Corporation Japan Orthopedic Biomechanics Institute Faculties of Engineering Yamaguchi University

No reports have described experiments designed to determine the strength characteristics of spinal nerve roots and rami radiculares for the purpose of explaining the complexity of symptoms of medullary cone lesions and cauda equina syndrome. In this study, to explain the pathogenesis of cauda equina syndrome, monoaxial tensile tests were performed to determine the strength characteristics of spinal nerve roots and rami radiculares, and analysis was conducted to evaluate the stress-strain relationship and strength characteristics. Using the same tensile test device, the nerve root and ramus radiculares isolated from the spinal cords of pigs were subjected to the tensile test and stress relaxation test at load strain rates of 0.1, 1, 10, and 100 s-1 under identical settings. The tensile strength of the nerve root was not rate dependent, while the ramus radiculares tensile strength tended to decrease as the strain rate increased. These findings provide important insights into cauda equina symptoms, radiculopathy, and clinical symptoms of the medullary cone.

关键词： nerve regeneration cauda equina syndrome monoaxial tensile tests radiculopathy strength characteristics stress-strain relationship lumbar spinal canal stenosis paralysis spinal cord neural degeneration

Withdrawing method of the stiffening tube incidentally inserted into the descending colon

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World Journal of Gastroenterology 2005年第34期11卷 5390-5391页

作者： Shinsaku Fukuda Tatsuya Mikami Tadashi Shimoyama norihiro Hanabata Hideki Iwamura Akihiro Munakata First Department of Internal Medicine Hirosaki University School of Medicine Hirosaki Japan Tsugaru Center Hospital for Adult Tsugaru Japan

We experienced a very rare complication of colonoscopy,a migration of stiffening tube into the colorectum. We herein introduce a withdrawing method of migrating stiffening tube incidentally inserted into the colorectum.A 65-year-old Japanese woman underwent colonoscopy because of abdominal discomfort. We used stiffening tube to insert the scope to the proximal colon because of her redundant sigmoid colon. When withdrawing the scope,we realized that the tube was fully inside the *** could not remove the tube instantly, and it reached the splenic flexure, finally. We reinserted the scope through the migrating tube, straightened the scope, and withdrew it holding a slight angle of the scope over the proximal end of the tube. Then, we could safely remove the tube along with the scope through the anus.

关键词： Colonoscopy Complication Migration Stiffening tube

Autoimmune pancreatitis complicated by gastric varices:A report of 3 cases

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World Journal of Gastroenterology 2012年第31期18卷 4228-4232页

作者： norihiro Goto Jun Mimura Toshinao Itani Motohito Hayashi Yukari Shimada Tomoaki Matsumori Department of Gastroenterology Nishi-Kobe Medical CenterHyogo 651-2273Japan

We present three cases of autoimmune pancreatitis(AIP) complicated by gastric *** 1:A 57-yearold man was diagnosed with AIP complicated by gastric varices and splenic vein *** was not detected at the time of the *** AIP improved using steroid therapy,the splenic vein was reperfused,and the gastric varices disappeared;case 2:A 55-year-old man was diagnosed with AIP complicated by gastric varices,splenic vein obstruction,and *** the AIP improved using steroid therapy,the gastric varices and splenic vein obstruction did not resolve;case 3:A 68-year-old man was diagnosed with AIP complicated by gastric varices,splenic vein obstruction,and *** gastric varices,splenic vein obstruction,and AIP did not improve using steroid *** three cases suggest that gastric varices or splenic vein obstruction without splenomegaly may be an indication for steroid therapy in patients with AIP because the complications will likely become irreversible over time.

关键词： Autoimmune Pancreatitis Gastric varices

Inhibition of KL-6/MUC1 glycosylation limits aggressive progression of pancreatic cancer

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World Journal of Gastroenterology 2014年第34期20卷 12171-12181页

作者： Huan-Li Xu Xin Zhao Ke-Ming Zhang Wei Tang norihiro Kokudo Department of Pharmacology School of Basic Medical SciencesCapital Medical University Department of Hepatobiliary Surgery 302 Hospital of Chinese People’s Liberation Army Hepato-Biliary-Pancreatic Surgery Division Department of SurgeryGraduate School of MedicineUniversity of TokyoTokyo 113-8654Japan

AIM: To evaluate the significance of KL-6/MUC1 (a type of MUC1) glycosylation in pancreatic cancer progression.

关键词： Benzyl-N-acetyl-alpha-galactosaminide Glycosylation KL-6/MUC1 Pancreatic carcinoma Tunicamycin

Clinicopathological utility of sialoglycoconjugates in diagnosing and treating colorectal cancer

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World Journal of Gastroenterology 2014年第20期20卷 6123-6132页

作者： Yoshinori Inagaki Jianjun Gao Peipei Song norihiro Kokudo Munehiro Nakata Wei Tang Hepato-Biliary-Pancreatic Surgery Division Department of Surgery Graduate School of Medicine the University of Tokyo Tokyo 113-8655 Japan Department of Applied Biochemistry Tokai University Hiratsuka Kanagawa 259-1292 Japan

Aberrant expression of glycoconjugates occurs during malignant transformation of cancer *** of sialoglycoconjugates in particular may play an important role in the progression,i.e.,invasion or metastasis,of *** types of sialoglycoconjugates have been investigated to clarify their biological significance and clinical utility in diagnosing and treating colorectal *** review focuses specifically on expression of mucin(MUC)1 and it suggests that MUC1with the specific structure of a sialo-oligosaccharide has biological significance in determining the metastatic potential of colorectal cancer cells and clinicopathological utility in evaluating the effectiveness of treatments and the prognosis for patients with colorectal *** studies are expected to contribute to the expanded use of cancer-associated sialoglycoconjugates in cancer diagnosis and therapy.

关键词： Sialoglycoconjugates Sialic acid Mucin 1 Colorectal cancer Invasion Metastasis

Characteristics of gas evolution profiles during coal pyrolysis and its relation with the variation of functional groups

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International Journal of Coal Science & Technology 2018年第4期5卷 452-463页

作者： Lu Zhang Shichao Qi norihiro Takeda Shinji Kudo Junichiro Hayashi Koyo Norinaga Department of Applied Science for Electronics and Materials Kyushu University6-1Kasuga KoenKasugaFukuoka 816-8580Japan Institute for Materials Chemistry and Engineering Kyushu University6-1Kasuga KoenKasugaFukuoka 816-8580Japan

Strict relation between the substituents or functional groups attached to the coal macromolecules and the generation of the volatile products, e.g., CH4 H2O, CO, CO2, etc., during the coal pyrolysis is an important but confusing subject. In this paper, quadrupole mass spectronletry, gas chromatography, and ^l3C nuclear magnetic resonance are applied to real-time monitoring the formations of volatile products, off-line quantitative determination of the total products from the pyrolysis of a sub-bituminous coal (SC), and the changes of diverse substitents in the SC along with coke foamation, respectively. These measurements are also performed for the pyrolysis of a caking coal to contrast SC. The qualitative and quantitative data reveal that, during coal pyrolysis, the functional groups related with the formation of CO, i.e., ether, carbonyl, and anhydride, can directly gen erate CO via bond breaking, or take a detour of the formation of other intermediates via condensation and recombination firstly. Moreover, the formations of CO2 and CH4 are related to the direct removal of -COO- and -CH3,respectively.

关键词： Light gas evolution Carbonization QMS GC ^13C NMR

Long-term effects of lamivudine treatment in Japanese chronic hepatitis B patients

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World Journal of Gastroenterology 2011年第24期17卷 2945-2952页

作者： Masayuki Murata norihiro Furusyo Mami Unno Eiichi Ogawa Kazuhiro Toyoda Hiroaki Taniai Hachiro Ohnishi Jun Hayashi Department of General Internal Medicine Kyushu University Hospital Department of Environmental Medicine and Infectious Disease Faculty of Medical SciencesKyushu University

AIM： To analyze the association between the emergence of tyrosine-methionine-asparatate-asparatate （YMDD） mutants （reverse transcription; rtM204I/V） and deterioration of liver function during long-term lamivudine treatment of Japanese patients with chronic hepatitis B virus （HBV） infection. METHODS： The data of 61 consecutive Japanese pa- tients with chronic hepatitis B who underwent continu- ous lamivudine treatment for more than 24 mo and had a virological response were analyzed. Analysis of YMDD mutants was done by real-time polymerase chain reaction with LightCycler probe hybridization assay for up to 90 mo （mean, 50.8 too; range, 24-90 too）.RESULTS： A mixed mutant-type （YMDD ＋ tyrosine-iso- leucine-asparatate-asparatate： YIDD or tyrosine-valineasparatate-asparatate： YVDD） or a mutant-type （YIDD or YVDD） were found in 57.4% of 61 patients at i year, 78.7% of 61 patients at 2 years, 79.6% of 49 patients at 3 years, 70.5% of 34 patients at 4 years, 68.4% of 19 patients at 5 years, 57.1% of 14 patients at 6 years, and 33.3% of 6 patients at 7 years. Of the 61 patients, 56 （92%） had mixed mutant- or a mutant-type. Only 5 （8%） had no mutants at each observation point. Vi- rological breakthrough was found in 26 （46.4%） of 56 patients with YMDD mutants, 20 of whom had a hepa- titis flare-up： the remaining 30 （53.6%） had neither a virological breakthrough nor a flare-up. All 20 patients who developed a hepatitis flare-up had a biochemical and virological response after adefovir was added to the lamivudine treatment. CONCLUSION： Our results suggest that it is possible to continue lamivudine treatment, even after the emergence of YMDD mutants, up to the time that the patients develop a hepatitis flare-up.

关键词： Tyrosine-methionine-asparatate-asparatatemutant Hepatitis B virus Lamivudine Drug resistance

Transient receptor potential vanilloid 1-immunoreactive signals in murine enteric glial cells

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World Journal of Gastroenterology 2016年第44期22卷 9752-9764页

作者： Masahiro Yamamoto Mitsue Nishiyama Seiichi Iizuka Shigeaki Suzuki norihiro Suzuki Sadakazu Aiso Jin Nakahara Tsumura Research Laboratories Tsumura & Co. Department of Neurology Keio University School of Medicine Department of Anatomy Keio University School of Medicine

AIM To investigate the possible involvement of transient receptor potential vanilloid 1(TRPV1) in maturation of enteric glial cells(EGCs).METHODS Immunohistochemical and immunocytochemical techniques were used to analyze EGC markers in myenteric plexus(MP) as well as cultured MP cells and EGCs using TRPV1 knockout(KO) *** We detected TRPV1-immunoreactive signals in EGC in the MP of wild-type(WT) but not KO mice. Expression of glial fibrillary acidic protein(GFAP) immunoreactive signals was lower at postnatal day(PD) 6 in KO mice, though the difference was not clear at PD 13 and PD 21. When MP cells were isolated and cultured from isolated longitudinal muscle-MP preparation from WT and KO mice, the yield of KO EGC was lower than that of WT EGC, while the yield of KO and WT smooth muscle cells showed no difference. Addition of BCTC, a TRPV1 antagonist, to enriched EGC culture resulted in a decrease in the protein ratio of GFAP to S100 B, another EGC/astrocyte-specific marker. CONCLUSION These results address the possibility that TRPV1 may be involved in the maturation of EGC, though further studies are necessary to validate this possibility.

关键词： Enteric glial cells Enteric nervous system Glial fibrillary acidic protein S100B Smooth muscle cells