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Multiple Major Thrombo-Embolic Events, including Stroke, in a Patient with Combined Congenital Anti-Thrombin III Deficiency and MTHFR Homozygous Mutation

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World Journal of Cardiovascular Diseases 2017年第3期7卷 71-78页

作者： Islam I. Zaid nora I. Abbas Ehab Shaker Foad Abd-Allah Departement of Neurology Faculty of Medicine Cairo University Cairo Egypt Departement of Critical Care Medicine Faculty of Medicine Cairo University Cairo Egypt

We report a case of a young male patient suffering from congenital Anti-Thrombin III (AT III) deficiency, presented with four major thrombotic events. These events were acute coronary syndrome (Non-ST elevation myocardial infarction), cerebral infarction, peripheral acute upper limb (UL) ischemia and bilateral extensive deep venous thrombosis. The latter two developed despite that the patient was receiving full anticoagulation therapy. His International normalized ratio (INR) was 2.5. Eventually, the patient developed pulmonary embolism and died. He had a prominent family history of thrombotic events. Screening for AT III deficiency in young patients with thrombotic event (thrombophilia) is essential especially those having family history of the latter. This is justified as thrombotic events may occur in up to 80% of these patients. Our patient with 4 major thrombotic events ending in fatality in less than 1 month deserves the nomenclature.

关键词： Thrombophilia Thrombosis Congenital AT III Deficiency Stroke Acute Coronary Syndrome Deep Venous Thrombosis Acute Limb Ischemia

Energy Audit in the Meat Processing Industry—A Case Study in Hermosillo,Sonora Mexico

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Journal of Environmental Protection 2016年第1期7卷 14-26页

作者： nora Munguia Luis Velazquez Tania Poom Bustamante Rafael Perez Johannes Winter Markus Will Bernd Delakowitz Sustainability Graduate Program Industrial Engineering Department University of Sonora Hermosillo Mexico Work Environment Department University of Massachusetts Lowell Lowell MA USA Faculty of Mathematics and Natural Sciences University of Applied Sciences Zittau/Gorlitz Zittau Germany

The meat processing industry, due to its high energy consumption, needs to be assessed in an energy usage basis. This paper reports the results and implications of an energy audit in a meat processing industry. In addition, this work provides a comprehensive and practical approach to energy saving measures in the assessed company to recognize factors that can determine a possible transition to sustainable patterns of electricity consumption. The paper described the application to energy auditing, developed by AFNOR (2014) for efficient energy management along with ISO 50001 (energy management systems). For a more specific energy auditing the guide described by Dall “O” (2013) was used. In this case, a study of an integrative characterization of the company’s energy consumption is made. The research has been divided in two main sections: the first includes an analysis about the characterization of the energy consumption within a meat processing company in the three sustainable approaches such as economical, societal and mainly environmental implications;second, a proposal for strategic energy management measures focusing on high consumer types of facilities. The results obtained allow the identification of main processes with significant correlations in terms of energy consumption within the company. This data has the potential for energy savings. The data acquisition process prompts the development of practical and accessible energy efficiency measures. In addition, a benchmarking analysis with several tools is performed. Altogether, this work gives guidance on the implementation of energy auditing in industries within its geographical and industrial sector limitations.

关键词： Energy Efficiency Energy Audits Energy Consumption Industrial Buildings

优秀的空气质量源于专业生物实验室通风换气设备的定期维护保养

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实验与分析 2015年第4期 24-25页

作者： nora Eckert Wisag工业服务控股公司

实验室空气质量必须达到标准，这不仅是为了在实验室中工作的实验员．也是为了实验室中那些非常敏感的实验样本。出于这一原因，德国海德堡市的欧洲分子生物实验室，会对实验室的通风换气设备定期进行维护保养。

关键词：生物实验室通风换气设备空气质量维护保养海德堡市实验员

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管理变革渐进式执行

软件世界 2005年第6期 73-74页

作者： nora Denzel 动成长企业战略和软件产品事业部

唯有提高灵活性方能使企业从容驾驭变革,而不为变革所羁绊。具备管理变革的能力,方能打造出灵活应变的成功企业。

关键词：管理变革渐进式执行高灵活性企业

The Institutionalization of Life Cycle Assessment in Mexico

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Journal of Environmental Protection 2015年第8期6卷 804-812页

作者： nora Munguia Clara Rosalia Alvarez Rafael Perez Alma Flores Francisco Martinez Luis Velazquez Sustainability Graduate Program University of Sonora Hermosillo Mexico Institute of Agro-Livestock Sciences Autonomous University of Mexico State Toluca Mexico

This article presents a study of Life Cycle Assessment (LCA) at a slaughterhouse located in north-western Mexico with the purpose of testing the premise of a low degree of institutionalization of Industrial Ecology in Mexico. The article aims at analyzing the current role played by the Mexican academia in increasing the degree of institutionalization of the concept of LCA in northwestern Mexico. There was conducted a life cycle analysis study according to the standards ISO 14040: 2006, NMX-SAA-14040-IMNC-2008NOM in a Federally Inspected Type (TIF by Spanish acronym) Slaughterhouse in the state of Sonora in Northwest Mexico. The slaughter process was characterized by observing the production tasks during several walkthroughs the production lines and by having short interviews with workers, supervisors, and the manager. The CH4 emissions were calculated using the guidelines suggested by the Intergovernmental Panel on Climate Change (IPCC 2006). The present LCA case study revealed opportunities for improving the environmental performance of the slaughterhouse by taking measures such as the reduction of CH4 from enteric fermentation since methane was one of the main greenhouse gases responsible for climate change. Although, the LCA generated reliable information in terms of climate change or water eutrophication, the chances of implementing sustainable initiatives were unlikely because the benefits to reduce the impacts to climate change or to reduce the water crisis would be unnoticeable and unaffordable for companies. Findings in this study also confirmed the importance of Mexican universities for promoting and conducting more LCA studies among private and public organizations in order to guide firms towards this tool. The case study here presented gives insights to LCA stakeholders in Mexico to implement or improve the effectiveness of their potential LCA initiatives through the identification of strategies, opportunities, and barriers.

关键词： Institutionalization Academia LCA Sustainability Slaughterhouse Mexico

Evaluation of the in vivo effect of ivermectin on Schistosoma mansoni in experimentally-infected mice

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Journal of Coastal Life Medicine 2014年第10期 817-823页

作者： Amira Taman Samar El-Beshbishi nora El-Tantawy Amira El-Hawary Manar Azab Department of Medical Parasitology Faculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Pathology Faculty of MedicineMansoura UniversityMansoura 35516Egypt

Objective:To evaluate the effect of ivermectin on mice experimentally infected with Schistosoma ***:Ivermectin was given to mice 42 days *** two treatment regimens:a single dose of 25 mg/kg or the same dose for two consecutive ***:In both regimens,there were significant reductions in female worms,hepatic tissue egg count and early immature ova,in addition to significant reductions in the count and size of hepatic *** same dose for two consecutive days resulted in significant reductions in male,total worms,and intestinal tissue egg *** both regimens,scaning electron microscopy revealed tegumental alternations as bleb formation,erosion and necrosis more evident with the double *** addition,high dose showed extensive erosions of male worms with destruction of the gynaecophoric *** females,marked destruction of the tegumental surface was extending to both ventral and oral ***:lvermnectin has promising anti--schistosomal ***,further research is needed to test the effect of ivermectin on schistosomiasis especially in combination with other antischistosomal agents,to avoid any possible resistance from monotherapy.

关键词： Schistosoma mansoni Ivermectin Praziquantel Scanning electron microscopy Tegument Glutamate

Mangroves and Pollution Control

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Mangroves and Pollution Control

Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico

第四届中国红树林学术会议

作者： nora F.Y. Tam Y.S. Wong Department of Biology and Chemistry City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong PRC. Vice-President and Department of Biology Hong Kong University of Science and Technology Clearwater Bay Kowloon Hong Kong PRC.

Due to rapid industrialization and urbanization, marine pollution becomes more and more serious in recent decades. Excess nutrients in coastal water cause eutrophication and red tide problems;while toxic chemicals pose harmful effects to our environments and human health. Mangroves, located between land and sea, have long been used as convenient waste dumping sites and inadvertently received untreated wastewater from various sources. The special properties of mangroves, such as high primary productivity and large nutrient demand, rapid litter decomposition and nutrient cycling, active and diverse microorganisms associated with sediments and roots suggest that mangroves have self-purification ability. Many people actually claimed that mangroves could be used to purify pollutants from wastewater and remedy contaminated sediment;however, systematic and scientific research on these areas is still rare. In the past ten years, according to a "quick search" using "Science Direct" , almost 1,000 SCI papers were published in "mangroves", but only 21 were on ’mangrove and sewage", and less than 10 were on "mangrove and bioremediation". It is clear that more research is needed to understand the significance of mangrove ecosystems as pollution control measures. The use of constructed wetland as wastewater treatment facility has attracted more and more attention in the past three decades, especially in North America, Europe and recently in Asia. Thousands of constructed wetland treatment systems of various sizes and capacities have been built. Plants such as common reeds, cattails, bulrush, etc. have been used. However, these plants require frequent harvesting which may make affect the consistency of the treatment efficiency. Disposal of plant materials is another operation problem. Mangroves, perennial woody plants, do not require any harvesting, their high productivity and nutrient demand, and their salinity tolerance actually make them good alternatives. The presentation will

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World Journal of Gastroenterology 2015年第41期21卷 11552-11566页

作者： Omar Ramos-Lopez Erika Martinez-Lopez Sonia Roman nora A Fierro Arturo Panduro Department of Molecular Biology in Medicine Civil Hospital of Guadalajara "Fray Antonio Alcalde" Guadalajara Jalisco Mexico and Health Sciences Center University of Guadalajara

Liver cirrhosis(LC) is a chronic illness caused by inflammatory responses and progressive fibrosis. Globally, the most common causes of chronic liver disease include persistent alcohol abuse, followed by viral hepatitis infections and nonalcoholic fatty liver disease. However, regardless of the etiological factors, the susceptibility and degree of liver damage may be influenced by genetic polymorphisms that are associated with distinct ethnic and cultural backgrounds. Consequently, metabolic genes are influenced by variable environmental lifestyle factors, such as diet, physical inactivity, and emotional stress, which are associated with regional differences among populations. This Topic Highlight will focus on the genetic and environmental factors that may influence the metabolism of alcohol and nutrients in the setting of distinct etiologies of liver disease. The interaction between genes and environment in the current-day admixed population, Mestizo and Native Mexican, will be described. Additionally, genes involved in immune regulation, insulin sensitivity, oxidative stress and extracellular matrix deposition may modulate the degree of severity. In conclusion, LC is a complex disease. The onset, progression, and clinical outcome of LC among the Mexican population are influenced by specific genetic and environmental factors. Among these are an admixed genome with a heterogenic distribution of European, Amerindian and African ancestry; a high score of alcohol consumption; viral infections; a hepatopathogenic diet; and a high prevalence of obesity. The variance in risk factors among populations suggests that intervention strategies directed towards the prevention and management of LC should be tailored according to such population-based features.

关键词： Genomic medicine Polymorphisms Viral hepatitis Obe

Acute pancreatitis revealing ulcerative colitis—A case report

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Open Journal of Gastroenterology 2014年第1期4卷 16-18页

作者： nora Bousfiha Iliass Iliass Charif Mohamed el Abkari Adil Ibrahimi Ihsane Mellouki School of Medicine and Pharmacy of Fez Sidi Mohammed Ben Abdellah University Fez Morocco

The association of acute pancreatitis with ulcerative colitis [UC] has been described in the literature. It is usually induced by drugs, but sometimes it may be idiopathic. This association remains rare. We report the case of a patient who was treated in our department. Medical observation: Mr. KA, a 60-year-old man, was admitted in our unit for management of acute epigastric. The clinical examination at the admission was normal. After eliminating a cardiac or surgical cause, the diagnosis of acute pancreatitis was made on the basis of the presence of a serum lipase up to 5 times the normal level and pain intensity. An abdominal scanner tomography was performed for the assessment of the pancreatitis. It has shown a pancreatitis stage C associated with a thick rectosigmoidien that was discovered incidentally. Symptomatology was enriched 10 days after by the occurrence of rectal bleeding. A lower endoscopy was performed after the improvement of the pancreatitis and had shown an ulcerative colitis on pancolitis which was confirmed by biopsy. In order to search other causes of this pancreatitis, other tests were made [a biliary IRM, endoscopic ultrasonography, autoimmune tests] and the results were negative. We concluded an idiopathic pancreatitis. The ulcerative colitis was classified as moderate and the patient was put on oral corticosteroids with degression. The evolution was marked by a clinical and biological improvement of pancreatitis and colitis. Conclusion: The association of idiopathic pancreatitis with ulcerative colitis is rare. The case of our patient is the first case reported in our series with 400 cases of ulcerative colitis diagnosed in our service.

关键词： Acute Pancreatitis Ulcerative Colitis