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Dietary analysis of Homonota darwini (Squamata:Gekkonidae) in Northern Patagonia

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Current Zoology 2010年第4期56卷 406-410页

作者： Marcelo e.KUN Carla PIANTONI John D.KreNZ nora r.ibargüe.goytía Departamento de Zoología Centro Regional Universitario Bariloche Universidad del Comahue Unidad Postal Universidad del Comahue Smithsonian Institution NHB MRC 163 Department of Biological Sciences Minnesota State University Departamento de Zoologia Centro Regional Universitario Bariloche Universidad del Comahue Unidad Postal Universidad del Comahue Instituto de Investigación en Diversidad y Medio Ambiente (INIBIOMA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICeT)

Our study investigated the diet of the southernmost gecko in the world, Homonota darwini. Fifty-three specimens were captured during spring and summer in four locations in Patagonia, Argentina. The stomach contents of the specimens were identified, and we tbund that prey consisted of six main groups： Coleoptera, Hymenoptera, Homoptera and Araneae, and the adults and larvae of moth Lepidoptera. Lepidoptera was the major dietary component. The presence of ants and moths as common prey suggests an ambush feeding strategy. In spring, females consumed more ants than males although no other dietary differences between males and females were evident. We tbund nine geckos with empty stomachs and six parasitized by nematodes. Presence of empty stomachs corroborates previous observations of other nocturnal geckos and non-gecko lizards. reduced foraging success of nocturnal lizards could be due to difficulty in prey detection due to dim light, reduced or erratic activity of insect prey at night, or shorter activity times of geckos relative to diurnal success. Sex and season were not associated with the incidence of empty stomachs. Principal component analysis showed that four food alternatives correlated with season. The constraint of nocturnality, coupled with low night-time temperatures restricting feeding to only a few hours after sunset, appear to have caused a generality of diet which may limit energy acquisition. We conclude that H. darwini is an arthropod generalist and likely an ambush forager, as are many other nocturnal gekkonids

关键词： Nocturnal lizards Diet Gekkonidae Patagonia PCA

Friction and wear performance of polyether ether ketone(PeeK)polymers in three lubrication regimes

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Friction 2024年第4期12卷 670-682页

作者： Davide MASSOCCHI nora LeCIS Marco LATTUADA Davide SCAGLIA Steven CHATTerTON Paolo PeNNACCHI Department of Mechanical engineering Politecnico di MilanoMilan 20156Italy eni SpA Downstream product R&DLombardia 20097Italy eurobearings S.r.L. Lombardia 29016Italy

This experimental study investigates the friction and wear of three coatings commonly used in industrial applications,particularly in hydrodynamic *** three materials under investigation were Babbitt,polyether ether ketone(PeeK)reinforced with 15%carbon fibers,and PeeK reinforced with 20%carbon *** first polymer material was extruded,while the other was produced by fused deposition modelling(FDM).The materials were subjected to sliding tests in a pin-on-disc configuration,with a steel ball serving as the counter *** tests were conducted at room temperature,with a load of 10 N and under three different lubrication conditions:dry,grease,and *** linear speed was set at 0.3 m/s for the dry and semi-solid lubrication tests,while for the oil tests,the speed was set at 0.25 m/*** greases used had consistency grades of NGLI 000 and NGLI *** ISO VG 68 circulation oil was used for the oil lubrication ***,thermodynamic analyses were performed under the most severe conditions(i.e.,dry)to investigate the steel-Babbitt and steel-PeeK contact.

关键词： hydrodynamic bearings polyether ether ketone(PeeK)polymers additive manufacturing grease lubrication sliding oil lubrication ball-on-disk tribology

Thermal biology and locomotor performance in Phymaturus calcogaster:are Patagonian lizards vulnerable to climate change?

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Integrative Zoology 2021年第1期16卷 53-66页

作者： rosa L.OBreGÓN Jose A.SCOLArO nora r.ibargüe.goytía Marlin MeDINA Instituto de Diversidad y evolución Austral (CENPAT-CONICET)Puerto MadrynArgentina Facultad de Ciencias Naturales Universidad Nacional de la Patagonia San Juan BoscoTrelewArgentina Instituto de Investigaciones en Biodiversidad y Medioambiente Consejo Nacional de Investigaciones Científicas y Técnicas(INIBIOMA-CONICET)San Carlos de BarilocheArgentina Centro de Investigación esquel de Montaña y estepa Patagónica Consejo Nacional de Investigaciones Científicas y Técnicas(CIEMEP-CONICET)EsquelArgentina

Behavioral and physiological traits of ectotherms are especially sensitive to fluctuations of environmental *** particular,niche-specialist lizards are dependent on their physiological plasticity to adjust to changing environmental *** of the genus Phymaturus are viviparous,mainly herbivorous,and inhabit only rock promontories in the steppe environments of Patagonia and the ***,we examine the vulnerability of the southernmost Phymaturus species to global warming:the endemic Phymaturus calcogaster,which lives in a mesic environment in eastern *** studied body temperatures in the field(T_(b)),preferred body temperatures in a thermogradient(T_(pref)),the operative(T_(e))and environmental temperatures,and the dependence of running performance on body *** had a mean T_(b)(27.04℃)and a mean Te(31.15℃)both lower than their preferred temperature(T_(pref)=36.61℃)and the optimal temperature for running performance(T_(o)=37.13℃).Lizard activity seems to be restraint during the early afternoon due high environmental ***,both,the high safety margin and warming tolerance suggest that the expected increase in environmental temperatures due to global warming(IPCC report in 2018)would not threaten,but indeed enhance locomotor performance in this population.

关键词： climate change cold environment locomotor performance Patagonia Phymaturus

reproductive strategies in males of the world’s southernmost lizards

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Integrative Zoology 2017年第2期12卷 132-147页

作者： Jimena B.FerNÁNDeZ Marlin MeDINA erika L.KUBISCH JoséA.SCOLArO nora r.ibargüe.goytía INIBIOMA-CONICeT Zoology DepartmentCentro Regional Universitario Bariloche InstituteUniversidad Nacional del ComahueSan Carlos de BarilocheArgentina CIeMeP-CONICeT Biology DepartmentUniversidad Nacional de la Patagonia San Juan BoscoEsquelArgentina CeNPAT-CONICeT Universidad Nacional de la Patagonia San Juan BoscoTrelewArgentina

reproductive and life history patterns in reptiles are tightly related to the environmental conditions,so male reproductive cycles have been historically characterized as continuous,for tropical lizards,or seasonal,for temperate ***,males of Liolaemus and Phymaturus lizards(Liolaemidae),from cold temperate climates of high altitudes or latitudes in Argentina and Chile,have developed a variety of reproductive cycles to coordinate with the short female reproductive season and to deal with the low frequency of reproductive females in the *** gonadal histology and morphological analysis,we describe the male reproductive biology,fat storage and sexual dimorphism of the viviparous lizards Liolaemus sarmientoi and Liolaemus magellanicus that inhabit an austral grass steppe at 51°S,in the southern limit of the American *** of *** and *** are reproductively available during the entire activity season of approximately 5 *** addition,males of both species exhibit greater body sizes than females in morphological variables relevant in sexual ***,females of both species exhibit larger inter-limb length than conspecific males,which suggests fecundity selection to increase space for a larger litter *** continuous sperm production throughout the activity season allows these liolaemids to mate at any time when females ovulate,representing a selective advantage to deal with the short activity season and the adversities of the cold environment they inhabit.

关键词： adaptations Liolaemidae reproductive activity sexual dimorphism temperate-cold environments

Non-pancreatic hyperlipasemia:A puzzling clinical entity

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World Journal of Gastroenterology 2024年第19期30卷 2538-2552页

作者： Krisztina eszter Feher David Tornai Zsuzsanna Vitalis Laszlo Davida nora Sipeki Maria Papp Division of Gastroenterology Department of Internal MedicineFaculty of MedicineUniversity of DebrecenDebrecen H-4032Hajdu-BiharHungary Kalman Laki Doctoral School of Biomedical and Clinical Sciences Faculty of MedicineUniversity of DebrecenDebrecen H-4032Hungary

BACKGrOUND Increased lipase level is a serological hallmark of the diagnosis of acute pancreatitis(AP)but can be detected in various other diseases associated with lipase leakage due to inflammation of organs surrounding the pancreas or reduced renal clearance and/or hepatic *** non-pancreatic hyperlipasemia(NPHL)is puzzling for attending physicians during the diagnostic procedure for *** would be clinically beneficial to identify the clinical and laboratory variables that hinder the accuracy of lipase diagnosis with the aim of improve it.A more precise description of the NPHL condition could potentially provide prognostic factors for adverse outcomes which is currently *** To perform a detailed clinical and laboratory characterization of NPHL in a large prospective patient cohort with an assessment of parameters determining disease *** A Hungarian patient cohort with serum lipase levels at least three times higher than the upper limit of normal(ULN)was prospectively evaluated over 31 *** were identified using daily electronic laboratory reports developed to support an ongoing observational,multicenter,prospective cohort study called the eASY trial(ISrCTN10525246)to establish a simple,easy,and accurate clinical scoring system for early prognostication of *** of NPHL was established based on≥3×ULN serum lipase level in the absence of abdominal pain or abdominal imaging results characteristic of *** A total of 808 patients[male,n=420(52%);median age(IQr):65(51-75)years]were diagnosed with≥3×ULN serum lipase levels.A total of 392 patients had AP,whereas 401 had NPHL with more than 20 different *** and acute kidney injury(AKI)were the most prevalent etiologies of NPHL(27.7%and 33.2%,respectively).The best discriminative cut-off value for lipase was≥666 U/L(sensitivity,71.4%;specificity,88.8%).The presence of AKI or sepsis negatively affected the diagnostic performance of *** w

关键词： Non-pancreatic hyperlipasemia Acute pancreatitis Glycoprotein 2 Acute kidney injury Sepsis Mortality

Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 341-349页

作者： nora A.elsayed Fatma SM Moawed esraa SA Ahmed Ahmed Hammad Omayma Ar Abo-Zaid Biochemistry and Molecular Biology Department Faculty of Vet.Med.Benha UniversityBenha cityEgypt Health radiation research National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt radiation Biology Department National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt

Objective:To assess the hepatoprotective effects of flavone on nicotine-induced liver ***:Thirty-six rats were allocated into six groups:the control group,the nicotine group,the flavone alone groups(10 and 25 mg/kg/body weight),and the nicotine groups treated with flavone(10 and 25 mg/kg/body weight).Liver function,oxidative stress,Nrf2 pathway(HO-1,Nrf2,and Keap-1),and inflammatory markers(IL-17,TNF-α,and NF-κB)were ***,a histopathological examination of liver tissues was ***:Nicotine increased liver damage,inflammation,and oxidative ***,flavone suppressed nicotine-induced liver enzymes,oxidative stress,and inflammation,as manifested by increased antioxidants and decreased malondialdehyde level,liver enzymatic activities,and inflammatory ***(10 and 25 mg/kg/body weight)also reduced the level of Keap-1 and increased HO-1 and Nrf2 levels in the liver of nicotine-exposed ***:Flavone has hepatoprotective properties and may slow the progression of liver injury by reducing oxidative stress,liver enzymes,and inflammation possibly via the Nrf2 pathway.

关键词： Flavone Nicotine Liver Nrf2 HO-1 NF-κB

Metabolic dysfunction-associated steatotic liver disease-associated fibrosis and cardiac dysfunction in patients with type 2 diabetes

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World Journal of Cardiology 2024年第10期16卷 580-594页

作者： Simona Cernea Danusia Onișor Andrada Larisa roiban Theodora Benedek nora rat Department M3/Internal Medicine I George Emil Palade University of MedicinePharmacyScience and Technology of Târgu MureșTârgu Mureş540142Romania Diabetes Nutrition and Metabolic Diseases Outpatient UnitEmergency County Clinical HospitalTârgu Mureş540136Romania Department Me2/Internal Medicine VII George Emil Palade University of MedicinePharmacyScience and Technology of Târgu MureşTârgu Mureş540142Romania Gastroenterology Clinic MureșCounty Clinical HospitalTârgu Mureş540103Romania Diabetes Compartment MediașMunicipal HospitalMediaș551030Romania Doctoral School of Medicine and Pharmacy George Emil Palade University of MedicinePharmacyScienceand Technology of Târgu MureşTârgu Mureş540142Romania Department M3/Internal Medicine VI George Emil Palade University of MedicinePharmacyScienceand Technology of Târgu MureşTârgu Mureş540142Romania Department of Cardiology Emergency County Clinical HospitalTârgu Mureş540136Romania

BACKGrOUND Metabolic dysfunction-associated steatotic liver disease(MASLD),particularly in the presence of liver fibrosis,increases the risk of cardiovascular morbidity and mortality,but the nature of the cardio-hepatic interaction in the context type 2 diabetes mellitus(T2DM)is not fully *** To evaluate the changes in cardiac morphology and function in patients with T2DM and MASLD-associated liver *** T2DM patients with MASLD underwent a medical evaluation that included an assessment of lifestyle,anthropometric measurements,vital signs,an extensive laboratory panel,and a standard *** fibrosis was evaluated using two scores[Fibrosis-4(FIB4)and Non-alcoholic fatty liver disease-Fibrosis Score(NFS)],and subjects were classified as having advanced fibrosis,no fibrosis,or an indeterminate *** correlations between structural and functional cardiac parameters and markers of liver fibrosis were evaluated through bivariate and multiple regression *** significance was set at Prom 267 T2DM-MASLD subjects with complete assessment was *** with scores indicating advanced fibrosis exhibited higher interventricular septum and left ventricular(LV)posterior wall thickness,atrial diameters,LV end-systolic volume,LV mass index(LVMi),and epicardial adipose tissue thickness(eATT).Their mean ejection fraction(eF)was significantly lower(49.19%±5.62%vs 50.87%±5.14%vs 52.00%±3.25%;P=0.003),and a smaller proportion had an eF≥50%(49.40%vs 68.90%vs 84.21%;P=0.0017).Their total and mid LV wall motion score indexes were higher(Pey had markers of diastolic dysfunction,with a higher e/e’ratio[9.64±4.10 vs 8.44(2.43-26.33)vs 7.35±2.62;P=0.026],and over 70%had lateral e’valuesecond,though without significant differences between *** multiple regression analyses,FIB4 correlated with left atrium diameter(LAD;β=0.044;Pright

关键词： Metabolic dysfunction-associated steatotic liver disease Type 2 diabetes mellitus Liver fibrosis Cardiac dysfunction Sex-hormone binding protein

Hard life for sons in the nest?Sex-dependent offspring mortality in Great Tits in urban and forest areas

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Avian research 2024年第1期15卷 91-97页

作者： nora Agh Henriett Anna Dalvári Krisztián Szabó Ivett Pipoly András Liker HUN-reN-Pe evolutionary ecology research Group University of PannoniaH-8200VeszpremPf.1158.Hungary Behavioral ecology research Group Center for Natural SciencesUniversity of PannoniaH-8200Pf.1158.VeszpremHungary Molecular ecology research Group Department of EcologyUniversity of Veterinary Medicine BudapestH-1400Pf.2.BudapestHungary Synlab Hungary Ltd. H-1211Weiss Manfr´ed Str.5-7BudapestHungary

Sex-biased mortality can occur in birds during development,for example due to sexual differences in energy requirement and/or environmental sensitivity,or the effects of sex hormones or sex differences in the expression of mutations linked to sex *** extent of sex-bias in mortality may also be related to environmental conditions that influence offspring development and *** areas often provide poorer conditions for nestling development resulting in higher offspring mortality compared to natural areas,which may accelerate sex differences in offspring mortality in *** test this hypothesis,we examined the sex ratio of dead offspring in Great Tits(Parus major),using 427 samples of unhatched eggs and dead nestlings collected in two urban and two forest sites between 2013 and *** ratio of males in the whole sample of dead offspring(56.9%)was significantly higher than expected by an 1:1 ratio,and the strongest sex biases were detected in urban areas(57.6%males)and in young nestlings(es).However,the sex ratios of dead offspring did not differ significantly among study sites and between offspring developmental stages.29.3%of unhatched eggs contained a visible embryo,and the proportion of embryo-containing unhatched eggs did not differ significantly between urban and forest study *** results suggest male-biased offspring mortality in Great Tits,and highlight the need of large datasets to detect subtle differences between habitats and developmental stages.

关键词： Great Tit Urbanization Nestling mortality Sex related differences

recovery rates and long-term olfactory dysfunction following COVID-19 infection

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 121-128页

作者： Melanie Dias Zara Shaida nora Haloob Claire Hopkins eNT Department Guy's HospitalLondonUK

Objectives:Olfactory dysfunction is one of the most recognized symptoms of COVID-19,significantly impacting quality of life,particularly in cases where recovery is *** review aims to explore patterns of olfactory recovery post-COVID-19 infection,with particular focus on delayed *** Sources:Published literature in the english language,including senior author's own work,online and social media platforms,and patients'anecdotal ***:A comprehensive review of the literature was undertaken by the authors with guidance from the senior author with expertise in the field of ***:Based on self-report,an estimated 95%of patients recover their olfactory function within 6 months post-COVID-19 ***,psychophysical testing detects higher rates of persistent olfactory *** has been found to continue for at least 2 years postinfection;negative prognostic indicators include severe olfactory loss in the acute phase,female sex,and older *** in quantitative and qualitative disturbance in prolonged cases likely reflects both peripheral and central pathophysiological *** of many of the reviewed studies reflect lack of psychophysical testing and baseline olfactory ***:Post-COVID-19 olfactory dysfunction remains a significant health and psychosocial *** evidence is improving awareness and knowledge among clinicians to better support patients through their olfactory rehabilitation,with hope of recovery after several months or *** research is needed to better understand the underlying pathogenesis of delayed recovery,identify at risk individuals earlier in the disease course,and develop therapeutic targets.

关键词： anosmia COVID-19 olfaction parosmia recovery